• Title/Summary/Keyword: Dead end

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Regression models for interval-censored semi-competing risks data with missing intermediate transition status (중간 사건이 결측되었거나 구간 중도절단된 준 경쟁 위험 자료에 대한 회귀모형)

  • Kim, Jinheum;Kim, Jayoun
    • The Korean Journal of Applied Statistics
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    • v.29 no.7
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    • pp.1311-1327
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    • 2016
  • We propose a multi-state model for analyzing semi-competing risks data with interval-censored or missing intermediate events. This model is an extension of the 'illness-death model', which composes three states, such as 'healthy', 'diseased', and 'dead'. The state of 'diseased' can be considered as an intermediate event. Two more states are added into the illness-death model to describe missing events caused by a loss of follow-up before the end of the study. One of them is a state of 'LTF', representing a lost-to-follow-up, and the other is an unobservable state that represents the intermediate event experienced after LTF occurred. Given covariates, we employ the Cox proportional hazards model with a normal frailty and construct a full likelihood to estimate transition intensities between states in the multi-state model. Marginalization of the full likelihood is completed using the adaptive Gaussian quadrature, and the optimal solution of the regression parameters is achieved through the iterative Newton-Raphson algorithm. Simulation studies are carried out to investigate the finite-sample performance of the proposed estimation procedure in terms of the empirical coverage probability of the true regression parameter. Our proposed method is also illustrated with the dataset adapted from Helmer et al. (2001).

Fouling behaviours of two stages microalgae/membrane filtration system applied to palm oil mill effluent treatment

  • Teow, Yeit Haan;Wong, Zhong Huo;Takriff, Mohd Sobri;Mohammad, Abdul Wahab
    • Membrane and Water Treatment
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    • v.9 no.5
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    • pp.373-383
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    • 2018
  • Fouling by solids and microorganisms is the major obstacle limiting the efficient use of membrane wastewater treatment. In our previous study, two stages microalgae/membrane filtration system was proposed to treat anaerobic digested palm oil mill effluent (AnPOME). This two stages microalgae/membrane filtration system had showed great potential for the treatment of AnPOME with high removal of COD, $NH_3-N$, $PO_4{^{3-}}$, TSS, turbidity, and colour. However, fouling behavior of the membrane in this two stages microalgae/membrane filtration system was still unknown. In this study, empirical models that describe permeate flux decline for dead-end filtration (pore blocking - complete, intermediate, and standard; and cake layer formation) presented by Hermia were used to fit the experimental results in identifying the fouling mechanism under different experimental conditions. Both centrifuged and non-centrifuged samples were taken from the medium with 3 days RT intervals, from day 0 to day 12 to study their influence on fouling mechanisms described by Hermia for ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO) filtration mode. Besides, a more detailed study on the use of resistance-in-series model for deadend filtration was done to investigate the fouling mechanisms involved in membrane filtration of AnPOME collected after microalgae treatment. The results showed that fouling of UF and NF membrane was mainly caused by cake layer formation and it was also supported by the analysis for resistance-in-series model. Whereas, fouling of RO membrane was dominated by concentration polarization.

Finite element model updating effect on the structural behavior of long span concrete highway bridges

  • Altunisik, A.C.;Bayraktar, A.
    • Computers and Concrete
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    • v.14 no.6
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    • pp.745-765
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    • 2014
  • In this paper, it is aimed to determine the finite element model updating effects on the structural behavior of long span concrete highway bridges. Birecik Highway Bridge located on the 81stkm of Sanliurfa-Gaziantep state highway over Firat River in Turkey is selected as a case study. The bridge consist of fourteen spans, each of span has a nearly 26m. The total bridge length is 380m and width of bridge is 10m. Firstly, the analytical dynamic characteristics such as natural frequencies and mode shapes are attained from finite element analyses using SAP2000 program. After, experimental dynamic characteristics are specified from field investigations using Operational Modal Analysis method. Enhanced Frequency Domain Decomposition method in the frequency domain is used to extract the dynamic characteristics such as natural frequencies, mode shapes and damping ratios. Analytically and experimentally identified dynamic characteristics are compared with each other and finite element model of the bridge is updated to reduce the differences by changing of some uncertain parameters such as section properties, damages, boundary conditions and material properties. At the end of the study, structural performance of the highway bridge is determined under dead load, live load, and dynamic loads before and after model updating to specify the updating effect. Displacements, internal forces and stresses are used as comparison parameters. From the study, it is seen that the ambient vibration measurements are enough to identify the most significant modes of long span highway bridges. Maximum differences between the natural frequencies are reduced averagely from %46.7 to %2.39 by model updating. A good harmony is found between mode shapes after finite element model updating. It is demonstrated that finite element model updating has an important effect on the structural performance of the arch type long span highway bridge. Maximum displacements, shear forces, bending moments and compressive stresses are reduced %28.6, %21.0, %19.22, and %33.3-20.0, respectively.

Reliability-Based Design of Sight Distance, a Revisit (신뢰성을 고려한 도로 시거 설계의 제고)

  • Lee, Seul-Gi;Lee, Yong-Jae;Kim, Sang-Gi
    • Journal of Korean Society of Transportation
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    • v.24 no.1 s.87
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    • pp.121-131
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    • 2006
  • Considering characteristics of drivers and vehicles with proper and reliable ways in highway design Procedures can ensure high level of highway safety. However, it is almost impossible to take into account all factors of drivers and vehicles influencing on the highway safety because of their uncertain and random nature. To detour the dead-end, the nature are usually assumed as simple homogeneous and deterministic one. Although the restricted assumption makes the system simple, it can produce serious problems due to lack of considering variability in the system. This paper develops a reliability-based method for determining stopping sight distance(SSD) and intersection sight distance (ISD), which are crucial elements in highway alignment design. In the study, Hasofer-Lind method is adopted. which is a well-known first-order second moment reliability method (AFOSM) The results in this study show that if mean, variance, and distribution of a particular driver-vehicle parameter are known, more reliable sight distances can be applied in highway design procedures because we can reflect uncertainties and randomness. Thus, the Probabilistic method could be adopted in designing the sight distance(s) with the desired reliability level.

An Inquiry into the Taboo of the Burial Shroud (수의의 금기에 관한 고찰)

  • 남민이
    • The Research Journal of the Costume Culture
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    • v.7 no.3
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    • pp.50-57
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    • 1999
  • Folk belief, which originated with the rise of human existence is a fundamental and comprehensive mode of living that reflects sociocultural conditions. Adherents of folk belief accept a certain thing to be true and real without scientific authority and absolute certainty. Taboo can be seen as a king of folk belief. The object of this study is to examine the taboos in relation to the manufacturing process and the quality of the shroud and to shrouding customs. I will also try to find out the meaning and significance in this. Through this task, I hope to contribute to the enhanced understanding of the cultural characteristics, the spiritual life, and the views on after life of the Korean people. In Korea, it is considered to be propitious to prepare the shroud on the intercalary month of the leap year , as it allows one to enjoy longevity healthy and sound. Moreover, as this belief gives credence and repose while preparing for the “final departure”, this custom is relatively well observed. From the taboo concerning leap months, we infer that death as viewed as a commencement of a new life, which reveals a positive view on afterlife. This can be seen as a return to the origin of anti-universal space in this “bonus” month of anti-universal time. Taboos on the manufacturing process of the shroud is related to the belief that it allows the deceased to go the nest world without any hesistation or disturbances. This symbolizes the immortality of the human soul: I. e. that the human spirit does not end in this world but continues on to the next. Taboos concerning the preparation process of the shroud as well as various other taboos are related to the belief that preparation for the shroud should be done in sincerity and secredness with a thoughtful consideration for the deceased. This can be perceived as an implication to sanctity for the dead.

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Biodegradation of Aromatic Compounds by Nocardioform Actinomycetes

  • CHA CHANG-JUN;CERNIGLIA CARL E.
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2001.11a
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    • pp.157-163
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    • 2001
  • Mycolic acid-containing gram-positive bacteria, so called nocardioform actinomycetes, have become a great interest to environmental microbiologists due to their metabolic versatility, multidegradative capacity and potential for bioremediation of priority pollutants. For example, Rhodococcus rhodochrous N75 was able to metabolize 4-methy1catechol via a modified $\beta$-ketoadipate pathway whereby 4-methylmuconolactone methyl isomerase catalyzes the conversion of 4-methylmuconolactone to 3-methylmuconolactone in order to circumvent the accumulation of the 'dead-end' metabolite, 4-methylmuconolactone. R. rhodochrous N75 has also shown the ability to transform a range of alkyl-substituted catechols to the corresponding muconolactones. A novel 3-methylmuconolactone-CoAsynthetase was found to be involved in the degradation of 3-methylmuconolactone, which is not mediated in a manner analogous to the classical $\beta$-ketoadipate pathway but activated by the addition of CoA prior to hydrolysis of lactone ring, suggesting that the degradative pathway for methylaromatic compounds by gram-positive bacteria diverges from that of proteobacteria. Mycobacterium sp. Strain PYR-l isolated from oil-contaminated soil was capable of mineralizing various polyaromatic hydrocarbons (PAHs), such as naphthalene, phenanthrene, pyrene, fluoranthrene, 1-nitropyrene, and 6-nitrochrysene. The pathways for degradation of PAHs by this organism have been elucidated through the isolation and characterization of chemical intermediates. 2-D gel electrophoresis of PAH-induced proteins enabled the cloning of the dioxygenase system containing a dehydrogenase, the dioxygenase small ($\beta$)-subunit, and the dioxygenase large ($\alpha$)-subunit. Phylogenetic analysis showed that the large a subunit did not cluster with most of the known sequences except for three newly described a subunits of dioxygenases from Rhodococcus spp. and Nocardioides spp. 2-D gel analysis also showed that catalase-peroxidase, which was induced with pyrene, plays a role in the PAH metabolism. The survival and performance of these bacteria raised the possibility that they can be excellent candidates for bioremediation purposes.

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Charicteristics of Wonsam on An-dong Kim Clan's Tomb Relics in the later Chosun Dynasty (안동김씨모 출토 조선후기 원삼의 특징)

  • Lee Tae-Ok;Kim Hye-Young;Cho Woo-Hyun
    • Journal of the Korea Fashion and Costume Design Association
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    • v.7 no.2
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    • pp.61-74
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    • 2005
  • Wonsam, a type of korean women's gown in Choseon Dynasty, was used as a small ceremonial costume for queens, crown princesses and princesses and as a grand ceremonial costume for royal concubines and wives of high rank officials. It was also worn as a wedding dress for commoners. In the families of illustrious officials, it was also used as burial accessories or garments for the dead. In this context, Wonsam is a formal dress for the people's most important four ceremonies of coming-of-age, marriage, funeral, and ancestor worship. It is worth emphasizing the costume since it was widely and importantly used by all ranks of women, from royal families to commoners. Through the Wonsam of An-dong Kim Clan's, we can see what the society was like at the end of Choseon Dynasty. First, a status system that strictly divided costumes for each class, was, in many parts, broken down. Second, the highly wrought patterns and texture of fabrics of the Wonsam reveal that it was granted from Court, or, if woven by the Kim family, it is considered to be produced by the Court's craftsman or through technical transfer, considering that the weaving skills used are as good as those in Courts. Third, regarding the precise needlework that is uncomparable to textiles used by other illustrious officials families, the Wonsam is considered to be granted from Court or, produced through the needlework skills that were handed down from needlewomen in Courts. The Wonsam of An-dong Kim Clan's has noble beauty in it, with outstanding weaving skills, fabrics, needlework and shape. Thus, it is no exaggeration to say that it has those qualities to be the standard costume that inherits the tradition of Korean people.

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Evaluation for Approximate Bending Moment Coefficients of Non-Composite Form Deck One-Way Slab considering Unequaled Elastic Deflection of Steel Beams (철골보의 부동탄성처짐을 고려한 비합성데크 일방향 슬래브의 근사적인 휨모멘트 계수 평가)

  • Kim, Ho Soo;Lim, Young Do
    • Journal of Korean Society of Steel Construction
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    • v.18 no.3
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    • pp.373-383
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    • 2006
  • In a steel structural system, noncomposite form deck one-way slab is the plate element supported by four-edged steel beams with unequaled stiffness. However, design criterion has analyzed the one-way slab as the continuous beam. Because the end beams that support the one-way slab have elastic supports t hat cause different deflections according to the support conditions and locations, the bending moments corresponding to the support ic support effect is not considered in the design criterion. Accordingly, to conduct a reasonable estimation of approximate moment coefficients considering the unequaled elastic support conditions, this study analyzes and estimates various models with varia bles for the ratios of live load to dead load and pattern arangements of live loads and span lengths. The analytical methods considering the finite three-dimensional plate element, the two-dimensional elastic support and the infinite stifnes suport are performed.

Internet Access Charging under High Quality Contents Delivery (고품질 콘텐츠 제공환경하에서 인터넷 접속료 책정방안)

  • Jung, Choong-Young
    • The Journal of the Korea Contents Association
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    • v.17 no.11
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    • pp.588-599
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    • 2017
  • This paper analyzes internet access model between ISP, CP and end users where CP uses various technologies to provide direct access to ISP owning subscribers to consume its own contents in low cost and high quality. The level of access charge depends on the competitiveness of CP market. When CP market is perfect competitive, the level of access charge is identical to that of social optimum while when CP market is monopoly, the level of access charge is influenced by the sensitivity of the contents price to access charge for CP. The dead weight loss due to monopoly market in CP can be removed by the regulation of access charge. Socially optimal access charge in monopoly market of CP is lower than that in competitive market. This is because the regulator wants to set access price to lower level to reduce welfare loss from monopoly in CP market where CP determines the price to over marginal cost.

Effect of rc Mutation on Semen Characteristics, Spermatogenic Tissues and Testosterone Profile in Blind Rhode Island Red Cockerels

  • Arshami, J.;Cheng, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.701-705
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    • 2007
  • Seven rc mutant and seven normal male birds (Rhode Island Red suie, RIR) were used in this study to determine the effects of rc mutation on semen characteristics, testosterone profile and spermatogenic tissues. All birds were randomly selected at week 12 of age and housed in individual cages and were fed and watered ad libitum. The birds were exposed to a 14L:10D light cycle during experiment. Semen were collected at weeks 22 to 23 from each bird twice a week and evaluated for semen volume (SV), sperm concentration (SC), total sperm count (TSC), percent of sperm motility (%SM), dead sperm (%DS), and sperm metabolic activity (SMA). To determine the testosterone concentration (TC) in plasma, blood was collected at weeks 12, 16 and 18. Testicular tissue were collected, processed and evaluated for semineferous tubule diameter (STD), round spermatid number (RSN), percent elongated sperm (%ES) and semineferous tubules length (STL). Body weight (BW), comb weight (CW) and testes weight (TW) were weighted at the end of experiment (week 23). The SV, TSC and %SM were significantly higher in normal birds but the %DS was higher in blind birds (p<0.05). The SC did not differ significantly between the two groups but its value was higher in normal birds. The sperm metabolic activity in the first h of collection did not differ significantly between the two groups but after 24 h, the level of SMA in normal group was significantly higher (p<0.05). The level of TC did not differ significantly between the two genotype groups but normal birds had higher TC in all collections except the last one. The STD, RSN, %ES and STL in normal birds were higher when compared to blind birds but the differences were insignificant except for ES percent. The BW, CW and TW between the two groups did not differ significantly but the weights were higher in normal group compared to blind birds. Statistical analysis of semen characteristics, testosterone profile and histological factors were indicated detrimental effects of rc mutation in prepubertal RIR blind male birds due to lack of light.