• Ocean and Polar Research
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• v.41 no.2
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• pp.107-120
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• 2019

The frequency analysis of scientific terms using bibliographic information is a simple concept, but as relevant data become more widespread, manual analysis of all data is practically impossible or only possible to a very limited extent. In addition, as the scale of oceanographic research has expanded to become much more comprehensive and widespread, the allocation of research resources on various topics has become an important issue. In this study, the frequency analysis of scientific terms was performed using text mining. The data used in the analysis is a general-purpose scholarship database, totaling 2,878 articles. Hypoxia, which is an important issue in the marine environment, was selected as a research field and the frequencies of related words were analyzed. The most frequently used words were 'Organic matter', 'Bottom water', and 'Dead zone' and specific areas showed high frequency. The results of this research can be used as a basis for the allocation of research resources to the frequency of use of related terms in specific fields when planning a large research project represented by single word.

• Journal of Microbiology and Biotechnology
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• v.31 no.5
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• pp.726-732
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• 2021

In this study, we evaluated the immune-enhancing activity of kimchi-derived Lactobacillus plantarum 200655 on immune suppression by cyclophosphamide (CP) in ICR mice. Animals were fed distilled water or 1×10⁹ colony-forming unit/kg B.W. 200655 or Lactobacillus rhamnosus GG as a positive control for 14 days. An in vivo model of immunosuppression was induced using CP 150 and 100 mg/kg B.W. at 7 and 10 days, respectively. Body weight, spleen index, spleen weight, and gene expression were measured to estimate the immune-enhancing effects. The dead 200655 (D-200655) group showed an increased spleen weight compared to the sham control (SC) group. Similarly, the spleen index was significantly higher than that in the CP-treated group. The live 200655 (L-200655) group showed an increased mRNA expression of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-6 in splenocytes. Also, the iNOS and COX-2 mRNA expression was upregulated in the L-200655 group compared to the CP-only (SC) group. The phosphorylation of ERK and MAPK was also upmodulated in the L-200655 group. These results indicate that L. plantarum 200655 ameliorated CP-induced immune suppression, suggesting that L. plantarum 200655 may have the potential to enhance the immune system.

• Smart Structures and Systems
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• v.26 no.6
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• pp.781-796
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• 2020

Prediction of total sediment load is essential in an extensive range of problems such as the design of the dead volume of dams, design of stable channels, sediment transport in the rivers, calculation of bridge piers degradation, prediction of sand and gravel mining effects on river-bed equilibrium, determination of the environmental impacts and dredging necessities. This paper is aimed to investigate and predict the total sediment load of the Wadi Arbaat in Eastern Sudan. The study was estimated the sediment load by separate total sediment load into bedload and Suspended Load (SL), independently. Although the sediment records are not sufficient to construct the discharge-sediment yield relationship and Sediment Rating Curve (SRC), the total sediment loads were predicted based on the discharge and Suspended Sediment Concentration (SSC). The turbidity data NTU in water quality has been used for prediction of the SSC in the estimation of suspended Sediment Yield (SY) transport of Wadi Arbaat. The sediment curves can be used for the estimation of the suspended SYs from the watershed area. The amount of information available for Khor Arbaat case study on sediment is poor data. However, the total sediment load is essential for the optimal control of the sediment transport on Khor Arbaat sediment and the protection of the dams on the upper gate area. The results show that the proposed model is found to be considered adequate to predict the total sediment load.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.4
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• pp.1-13
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• 2013

Objectives: In this study, it was carried out to evaluate the acute oral toxicity of Root of Polygala teunifolia Willd. in Sprague-Dawley (SD) rats. Methods: Male and female rats were administered orally with Root of Polygala teunifolia Willd. water extract of 1,000 mg/kg (low dosage group), 2,000 mg/kg (middle dosage group) and 4,000 mg/kg (high dosage group). We daily observed number of deaths, clinical signs and gross findings for 7 days. After 7 days, we measured body and organs weight. Also we analyzed hematological changes. Results: No dead SD rats and no clinical signs were found during the experiment period. Also other specific changes were not found between control and treated groups in hematology and serum biochemistry. But we found out histopathological changes in liver fat tissues of female. In addition, there were no significant changes of gross body and individual organs weight. Conclusions: These results suggest that water soluble extract of Root of Polygala teunifolia Willd. has not acute oral toxicity and oral $LD_{50}$ value was over 4,000 mg/kg in SD rats.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.59 no.2
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• pp.188-193
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• 2014

Seed viability testing provides valuable information for assessing seed lot germinability. However, most testing methods require destruction of seed prior to test. Because the dissected seeds for viability test cannot be used further evaluation, the nondestructively X-ray photography technique that can be applied for the evaluation of seed quality has been developed. In order to know the validity and accuracy of X-ray photography technique in seed evaluation test that conducted to remove the abnormal seed from a seed lot, we have compared the results from tetrazolium viability test, germination test and X-ray contrast method in cotton. Metallic salts treatment increased the efficiency of X-ray photographic method by enhancing the penetration of X-ray in abnormal or damaged seeds rather than normal seeds that have strong and well-organized tissues in seed. Cotton seeds presoaked for 16 hr in distilled water followed by soaking into metallic salt solution (5% NaI in water) for 60 min were easily classified seeds into dead seed and viable seed based on the radiography images obtained by X-ray radiation. We concluded that soft X-ray photography was reliable to find out the various defective characters due to heat and mechanical damage of seeds.

• Journal of Korean Society of Water and Wastewater
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• v.22 no.1
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• pp.105-112
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• 2008

Disinfection is a basic and effective microorganism inactivation method and historically contributed a decrease in waterborne diseases. To guarantee the disinfection ability, improving T in CT value is important. Many indexes are used to estimate the hydraulic efficiency, however, these are black-box analysis. Therefore it is need to develope new estimation method. In this study, internal short-circuiting estimation method (ISEM) is developed using CFD and we inquire into the factor which causes increase of $T_{10}/T$ value as LW ratio increases. And the effect of shape on the relation of LW ratio and $T_{10}/T$ is analyzed. As LW ratio increases, internal short-circuiting index (ISI) of influent and effluent zone is rapidly reduced and recirculation and dead zone are reduced in channel zone. Therefore, as the $T_{10}/T$ value converges maximum value, ISI curve is changed from "V" shape to "U" shape and hydraulic efficiency is improved especially in downstream portion of clearwell. The less the shape ratio(width/length of clearwell) is the less the $T_{10}/T$ value is at a same LW ratio because the portion of turning zone increases as shape ration decreases, therefore more boundary separation is generated.

• Journal of The Korean Society of Agricultural Engineers
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• v.59 no.4
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• pp.1-15
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• 2017

Eutrophication of surface waters is of concern worldwide, because it can result in many undesirable water-quality and ecological problems, such as hypoxic 'dead' zones and harmful algal blooms, both associated with considerable economic costs. In this study, we used LSM (Land Surface Model) to simulate nitrogen in five major rivers in the Southern Korean Peninsula. The main objective of this research was to enhance nitrogen data for input of LM3V model in South Korea. Input data for nitrogen fluxes were categorized into three sections including agriculture fertilizer, livestock manure, atmosphere deposition, biological fixation, and sewage pollutants were used as the nitrogen input. For using LM3V model, the nitrogen input data were regenerated by considering states of agriculture and industry in South Korea at a $1/8^{\circ}$ resolution. Then, we simulated stream/river flows and N loads throughout the entire drainage networks in South Korea at a $1/8^{\circ}$ resolution. By using the same parameters for the entire country ($100,210km^2$), composed of 5 river basins with varying climate and land use, the model simulates spatial (11 sites) and temporal (1999~2010) patterns of flows and nitrate-N loads are resonable by comparing observed flow and nitrate-N loads. The r (Pearson's linear correlation) for water temperature, flow and nitrate-N at river were 080~0.93, 0.62~0.92 and 0.5~0.9 respectively. Based on enhanced N input data and model results, we find that LM3V model as land surface model can be applied in South Korea with interaction of atmosphere and land conditions.

• The Korean Journal of Emergency Medical Services
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• v.9 no.1
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• pp.33-41
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• 2005

In Korea, the number of those who were drowned of the dead by 'accident and injury' ranked the third of causes of death is over 2,300 people a year. So the Ministry of Home Affairs arranged '119 drowning rescue team' at frequent occurrence regions of drowning temporarily as a part of drowning rescue measures during every summer season and made perfection more perfect for safety control and rescue services at prevention areas of accidents. However, considering that the number of professional drowning rescuers is small and it is managed temporarily only for summer, the placement of special rescue team equipped with professional education and qualification should be ensured and quick lifesaving and first-aid treatment should be conducted, since much time is required to arrive at accident place after receiving accident report at 119 office, rapid rescue and relief have not been achieved. Therefore, the placement of special rescue team should be increased for reducing the personal damages by considering regional characteristics and in particular placement of more drowning rescue teams in Jeonnam region which has more seas and rivers is needed This study aims at analyzing relief activities and statistics to cope with water accidents and achieve qualitative growth of first-aid services, examining actual conditions of water accident relief team and personnel assignment, providing first-aid services of good quality and establishing improvement methods to increase operation of relief team.

• The Journal of the Korea Contents Association
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• v.15 no.6
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• pp.529-538
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• 2015

This study was carried out to evaluate the acute oral toxicity of Corydalis turtschaninovii BESS. in Sprague-Dawley(SD) rats. Male and female rats were administered orally with Corydalis turtschaninovii BESS water extract. We measured the number of death by clinical signs and gross findings for 7 days. After 7 days, we measured the whole body and individual organs' weight. We also analyzed hematological changes. The result, no dead SD rats and no clinical signs were found during the experiment period. Also other specific changes were not found between control and treated groups in hematology and serum biochemistry. The results indicated that there were no significant changes of gross body and individual organs weight in SD rats. These results suggest that water soluble extract of Corydalis turtschaninovii BESS. has not acute oral toxicity in SD rats.

• Korean Journal of Veterinary Pathology
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• v.5 no.1
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• pp.9-16
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• 2001

To investigate the effects of safflower seed supplementation diet on the hepatic injury of rats administered with carbon tetrachloride (CCI$_4$), histopathological changes were assessed following acute and chronic administration in rats. In acute cases, all rats in group fed with 10% safflower seed supplementation diet survived despite the administration of lethal doses of $CCl_4$. However, most rats in group fed with control diet died. The hepatic injuries of survived rats, in the histopathological findings, were mild compared to those of dead rats. In the chronic cases, livers of group 2 fed with control diet were more progressive in fatty changes and centrilobular necrosis than those of group 3 fed with 20%safflower seed diet. However, after six weeks, livers of group 2 and 3 showed severe necrosis and mild fibrosis at the same time. Group 5 fed with 10% safflower seed supplementation diet and water containing 0.05% phenobarbital sodium showed mild fatty changes and necrosis compared with group 4 fed with control diet and water containing 0.05% phenobarbital sodium at sixth week. At 8 to 10 wee71s after the administration of $CCl_4$, severe fibrosis. fatty changes and marked necrosis were observed in group 4, but hepatic injuries were less severe in group 5. The present results suggested that safflower seed has some protective effect in hepatic lesions and consequently delay the progression of hepatic fibrosis.