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http://dx.doi.org/10.5392/JKCA.2015.15.06.529

Toxicity study to Ensure the Safety of Corydalis turtschaninovii BESS  

Lee, Seung-Byum (세명대학교 외식경영학과)
Ha, Hun-Yong (세명대학교 한방바이오융합과학부)
Publication Information
The Journal of the Korea Contents Association / v.15, no.6, 2015 , pp. 529-538 More about this Journal
Abstract
This study was carried out to evaluate the acute oral toxicity of Corydalis turtschaninovii BESS. in Sprague-Dawley(SD) rats. Male and female rats were administered orally with Corydalis turtschaninovii BESS water extract. We measured the number of death by clinical signs and gross findings for 7 days. After 7 days, we measured the whole body and individual organs' weight. We also analyzed hematological changes. The result, no dead SD rats and no clinical signs were found during the experiment period. Also other specific changes were not found between control and treated groups in hematology and serum biochemistry. The results indicated that there were no significant changes of gross body and individual organs weight in SD rats. These results suggest that water soluble extract of Corydalis turtschaninovii BESS. has not acute oral toxicity in SD rats.
Keywords
Corydalis turtschaninovii BESS; Herbal Medicine; Toxicity; Functional Foods;
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