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Recent Discovery of Secondary Mineral Deposits in an Idaho Lava Tube

  • Kesner, David W.
    • Journal of the speleological society of Korea
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    • no.4
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    • pp.33-39
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    • 1996
  • Secondary mineral deposits of gypsum, mirabilite, thenardite, crisobolite have long been known and, in fact, are quite common in lava tubes of southwest Idaho. Until recently, calcium carbonate were found in a few tubes in very small amounts and were thought to be qu are. The recent ‘rediscovery’ of Helen's Hidden Hide - Away lava tube h significantly changed this thinking. The deposits in this lava tube are only quite extensive but extremely varied in structure. As this is a v recent discovery, only basic preliminary work will be presented in t paper. It is hoped this will stimulate intrest for further and more inte study of the lava tubes of southwestern Idaho.

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LARGE TIME CONVERGENCE FOR A CHEMOTAXIS MODEL WITH DEGENERATE LOCAL SENSING AND CONSUMPTION

  • Philippe Laurencot
    • Bulletin of the Korean Mathematical Society
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    • v.61 no.2
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    • pp.479-488
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    • 2024
  • Convergence to a steady state in the long term limit is established for global weak solutions to a chemotaxis model with degenerate local sensing and consumption, when the motility function is C1-smooth on [0, ∞), vanishes at zero, and is positive on (0, ∞). A condition excluding that the large time limit is spatially homogeneous is also provided. These results extend previous ones derived for motility functions vanishing algebraically at zero and rely on a completely different approach.

Long-Term Durability of Infliximab for Pediatric Ulcerative Colitis: A Retrospective Data Review in a Tertiary Children's Hospital in Japan

  • Shimizu, Hirotaka;Arai, Katsuhiro;Takeuchi, Ichiro;Minowa, Kei;Hosoi, Kenji;Sato, Masamichi;Oka, Itsuhiro;Kaburaki, Yoichiro;Shimizu, Toshiaki
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.1
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    • pp.7-18
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    • 2021
  • Purpose: The long-term efficacy and safety of infliximab (IFX) in children with ulcerative colitis (UC) have not been well-evaluated. Here, we reviewed the long-term durability and safety of IFX in our single center pediatric cohort with UC. Methods: This retrospective study included 20 children with UC who were administered IFX. Results: For induction, 5 mg/kg IFX was administered at weeks 0, 2, and 6, followed by every 8 weeks for maintenance. The dose and interval of IFX were adjusted depending on clinical decisions. Corticosteroid (CS)-free remission without dose escalation (DE) occurred in 30% and 25% of patients at weeks 30 and 54, respectively. Patients who achieved CS-free remission without DE at week 30 sustained long-term IFX treatment without colectomy. However, one-third of the patients discontinued IFX treatment because of a primary nonresponse, and one-third experienced secondary loss of response (sLOR). IFX durability was higher in patients administered IFX plus azathioprine for >6 months. Four of five patients with very early onset UC had a primary nonresponse. Infusion reactions (IRs) occurred in 10 patients, resulting in discontinuation of IFX in four of these patients. No severe opportunistic infections occurred, except in one patient who developed acute focal bacterial nephritis. Three patients developed psoriasis-like lesions. Conclusion: IFX is relatively safe and effective for children with UC. Clinical remission at week 30 was associated with long-term durability of colectomy-free IFX treatment. However, approximately two-thirds of the patients were unable to continue IFX therapy because of primary nonresponse, sLOR, IRs, and other side effects.

Manipulation of Tissue Energy Metabolism in Meat-Producing Ruminants - Review -

  • Hocquette, J.F.;Ortigues-Marty, Isabelle;Vermorel, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.5
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    • pp.720-732
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    • 2001
  • Skeletal muscle is of major economic importance since it is finally converted to meat for consumers. The increase in meat production with low costs of production may be achieved by optimizing muscle growth, whereas a high meat quality requires, among other factors, the optimization of intramuscular glycogen and fat stores. Thus, research in energy metabolism aims at controling muscle metabolism, but also liver and adipose tissue metabolism in order to optimize energy partitioning in favour of muscles. Liver is characterized by high anabolic and catabolic rates. Metabolic enzymes are regulated by nutrients through short-term regulation of their activities and long-term regulation of expression of their genes. Consequences of liver metabolic regulation on energy supply to muscles may affect protein deposition (and hence growth) as well as intramuscular energy stores. Adipose tissues are important body reserves of triglycerides, which result from the balance between lipogenesis and lipolysis. Both processes depend on the feeding level and on the nature of nutrients, which indirectly affect energy delivery to muscles. In muscles, the regulation of rate-limiting nutrient transporters, of metabolic enzyme activities and of ATP production, as well as the interactions between nutrients affect free energy availability for muscle growth and modify muscle metabolic characteristics which determine meat quality. The growth of tissues and organs, the number and the characteristics of muscle fibers depend, for a great part, on early events during the fetal life. They include variations in quantitative and qualitative nutrient supply to the fetus, and hence in maternal nutrition. During the postnatal life, muscle growth and characteristics are affected by the age and the genetic type of the animals, the feeding level and the diet composition. The latter determines the nature of available nutrients and the rate of nutrient delivery to tissues, thereby regulating metabolism. Physical activity at pasture also favours the orientation of muscle metabolism, towards the oxidative type. Consequently, breeding systems may be of a great importance during the postnatal life. Research is now directed towards the determination of individual tissue and organ energy requirements, a better knowledge of nutrient partitioning between and within organs and tissues. The discovery of new molecules (e. g. leptin), of new molecular mechanisms and of more powerful techniques (DNA chips) will help to achieve these objectives. The integration of the different levels of knowledge will finally allow scientists to formulate new types of diets adapted to sustain a production of high quality meat with lower costs of production.

Watch and Wait in Lebanese Chronic Lymphocytic Leukemia Patients: How Relevant is it?

  • Lutfallah, Antoine Abi;Kourie, Hampig Raphael;Eid, Roland;Farhat, Fadi;Ghosn, Marwan;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.215-217
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    • 2016
  • Background: Chronic lymphocytic leukemia (CLL) is the most frequent form of leukemia in Europe and North America, and it mainly affects older individuals. Many approaches are implemented in the management of CLL from a watch and wait (W&W) strategy to chemotherapeutic regimens. We here reviewed our clinical practice for the relevance of the W&W strategy in Lebanese CLL patients. Materials and Methods: A total of 95 patients with CLL diagnosed in four institutions in Lebanon, between 1992 and 2013, were selected and their files were reviewed. Characteristics of these patients were noted including age, sex, RAI and Binet scores, CBC values, presence of hepatomegaly or splenomegaly, performance of bone marrow biopsy or peripheral blood flux cytometry for diagnosis, adoption of W&W strategy, different chemotherapeutic regimens and the indications for treatment. Results: Some 38 patients (40%) diagnosed with CLL were women and 57 (60%) were men with a mean age of 65.1 years [36-89]. Of the total, 50.5%, 17.2%, 14%, 7.5% and 10.8% had an RAI score at diagnosis of 0, 1, 2, 3 and 4, respectively, while 65.6%, 17.2% and 17.2% had Binet scores of I, II and III. The mean lymphocyte count at diagnosis was $39885/mm^3$ [1596-290000], the mean hemoglobin level was 12.7 g/dl [6.2-17] and the mean platelet count was $191255/mm^3$ [14000-458000]. While 26.3% of patients with CLL had splenomegaly, only 7.4% had hepatomegaly. Some 33.7% had undergone a bone marrow biopsy, 66.3% flow cytometry of circulating blood and 5.3% a lymph node biopsy. Overall, the W&W was adopted in 62.4% (58) of patients with a mean duration of 37.7 months [3-216]. The W&W was used in 82.6%, 73.3%, 46.2%, 14.3% and 0% of patients having RAI scores of 0, 1, 2, 3 and 4, respectively, and, it was used in 80%, 46.7% and 6.25% with Binet scores of I, II and III. The most frequent indication for treatment was anemia and thrombocytopenia, accounting for 32.7% of cases. The most frequently used chemotherapeutical regimens were chlorambucil until the end of the last century and flufarabine-cyclophosphamide-rituximab during the last decade. Conclusions: This retrospective review of CLL clinical practice showed an important implementation of the W&W strategy with a long duration, especially in early stage cases with low RAI or Binet scores.

An Efficient Chloride Ingress Model for Long-Term Lifetime Assessment of Reinforced Concrete Structures Under Realistic Climate and Exposure Conditions

  • Nguyen, Phu Tho;Bastidas-Arteaga, Emilio;Amiri, Ouali;Soueidy, Charbel-Pierre El
    • International Journal of Concrete Structures and Materials
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    • v.11 no.2
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    • pp.199-213
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    • 2017
  • Chloride penetration is among the main causes of corrosion initiation in reinforced concrete (RC) structures producing premature degradations. Weather and exposure conditions directly affect chloride ingress mechanisms and therefore the operational service life and safety of RC structures. Consequently, comprehensive chloride ingress models are useful tools to estimate corrosion initiation risks and minimize maintenance costs for RC structures placed under chloride-contaminated environments. This paper first presents a coupled thermo-hydro-chemical model for predicting chloride penetration into concrete that accounts for realistic weather conditions. This complete numerical model takes into account multiple factors affecting chloride ingress such as diffusion, convection, chloride binding, ionic interaction, and concrete aging. Since the complete model could be computationally expensive for long-term assessment, this study also proposes model simplifications in order to reduce the computational cost. Long-term chloride assessments of complete and reduced models are compared for three locations in France (Brest, Strasbourg and Nice) characterized by different weather and exposure conditions (tidal zone, de-icing salts and salt spray). The comparative study indicates that the reduced model is computationally efficient and accurate for long-term chloride ingress modeling in comparison to the complete one. Given that long-term assessment requires larger climate databases, this research also studies how climate models may affect chloride ingress assessment. The results indicate that the selection of climate models as well as the considered training periods introduce significant errors for mid- and long- term chloride ingress assessment.

What is the Meaning of Black in Korean Traditional Mourning Dress?

  • Park, Saet Byul;DeLong, Marilyn
    • International Journal of Costume and Fashion
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    • v.14 no.2
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    • pp.81-96
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    • 2014
  • The meanings of colors vary with time and space. For the most important events in a person's life, such as wedding or funeral, people use color to symbolize their identities or roles. Traditionally, the colors of dress had indicated the wearer's age, class, or marital status in Korea. However, Korea's exposure to western cultures has affected in many dimensions of its modern history. Especially, influenced by social change, the traditional dress has undergone many modifications in forms, silhouettes, materials, and color. However, women's mourning dress has been maintained as a long lasting tradition and the use of white in mourning dress has been regarded as a norm until recently, while men have worn a regular black suit with a black tie. But, the shift from white to black in mourning dress has been observed in recent mourning practices. To examine this change of color in Korean traditional mourning dress, a historical approach utilizing multiple resources, such as interview, observations of events, documents, and archival records was applied.

The Application of Pre-Breakdown Partial Discharge Detection Method for Breakdown of Investigation of Long Distance XLPE Cable (장조장 XLPE 케이블 절연 파괴 원인 규명을 위한 전구차단 장치의 응용)

  • Lee, C.Y.;Kim, D.W.
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1827-1829
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    • 2002
  • This paper describes AC test for long delivered drum length of cable using pre-breakdown partial discharge detection(PPD) method, which can be applied to observe the causes of electrical breakdown of EHV XLPE insulation. This method is to de-energize applied voltage to cable rapidly using pre-breakdown partial discharge, and is able to prevent complete breakdown. By this effect, defects such as voids, metal particles and protrusion in cable can be observed clearly. AC resonant test set was used for PPD method. Localization of partial discharge was performed by time difference detection of the traveling wave. Accuracy of localization was 1% to the length of test cable. Through several experiments with XLPE cable, successful results of PPD method were obtained.

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Interference Effects of Low-Power Devices on the UE Throughput of a CR-Based LTE System

  • Kim, Soyeon;Sung, Wonjin
    • Journal of electromagnetic engineering and science
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    • v.14 no.4
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    • pp.353-359
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    • 2014
  • Recently, the use of mobile devices has increased, and mobile traffic is growing rapidly. In order to deal with such massive traffic, cognitive radio (CR) is applied to efficiently use limited-spectrum resources. However, there can be multiple communication systems trying to access the white space (unused spectrum), and inevitable interference may occur to cause mutual performance degradation. Therefore, understanding the effects of interference in CR-based systems is crucial to meaningful operations of these systems. In this paper, we consider a long-term evolution (LTE) system using additional spectra by accessing the TV white space, where low-power devices (LPDs) are licensed primary users, in addition to TV broadcasting service providers. We model such a heterogeneous system to analyze the co-existence problem and evaluate the interference effects of LPDs on LTE user equipment (UE) throughput. We then present methods to mitigate the interference effects of LPDs by 'de-selecting' some of the UEs to effectively increase the overall sector throughput of the CR-based LTE system.