• Title/Summary/Keyword: De-yi

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Clinical Observations on Treatment for Chinese Patients with Gastrointestinal Stromal Tumors

  • He, Zhan-De;Huang, Xin-En;Zhou, Jian-Nong
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5111-5113
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    • 2015
  • Background: To investigate the diagnostic and treatment methods for Chinese patients with gastrointestinal stromal tumor (GIST). Materials and Methods: From January 2004 to June 2014, patients diagnosed with primary GIST and treated by a single medical team in the Department of Digestive Disease of XuYi Hospital of Traditional Chinese Medicine were retrospectively recruited. Re-examination and follow-up was conducted regularly and abdominal enhanced CT, blood biochemistry and responses to surgery or imatinib were recorded. Results: A total of 15 patients were enrolled, including 9 male and 6 female patients, with an average age of 54 years (ranging from 32-81 years). The primary symptoms were abdominal uncomfortable in 5 patients, abdominal pain in 6 patients as well as nausea and vomiting in 4 patients. One patient was diagnosed with bowl obstruction at the first visit. All patients were treated with surgery, and tumor site was confirmed 1 esophagus, 6 stomach, 4 small bowel, and 4 colorectal and all patients were pathologically diagnosed with GIST. Immunochemical test positive for CD 117 was found 12 patients, and positive for CD 34 in7 patients. The median follow-up time was 24 months (range of 3-63). Three metastasis were confirmed 1.5, 2 and 2.6 years postoperatively. Three patients were treatment by imatinib postoperatively. Conclusions: Surgery remains the main treatment method for Chinese patients with GIST and imatinib could be feasible and safe for treating Chinese patients with GIST.

Combined Effects of Aerobic Exercise Training and Diacylglycerol Ingestion on Blood Lipid Profiles and Resting Metabolic Rate Changes in Obese Man (유산소운동과 diacylglycerol 섭취가 비만인의 혈중 지질성분 및 안정 시 대사량의 변화에 미치는 영향)

  • Lee, Moon-Youl;Paik, Il-Young;Kwak, Yi-Sub
    • Journal of Life Science
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    • v.20 no.8
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    • pp.1261-1267
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    • 2010
  • The aim of this study was to investigate the combined effects of aerobic training and diacylglycerol ingestion on lipid profiles and resting metabolic rate changes in obese men. The subjects were divided into 3 groups: the Diacylglycerol group (D, n=6), aerobic training group (E, n=6), and diacylglycerol ingestion and aerobic training group (DE, n=6). Diacylglycerol was ingested and aerobic exercise training performed for 12 weeks. The information from the research was calculated through a Windows SPSS/PC+ Ver. 12.0K statistics package to standardize the means and deviations for each group. Then, two-way repeated measures ANOVA was used to evaluate the research hypothesis. Percent body fat, blood lipid profiles and resting metabolic rate changes were tested to evaluate the combined effect of aerobic exercise training and diacylglycerol ingestion. The results of this study were as follows; DG ingestion was shown to have a positive effect on body weight and body fat, while having a negative effect on resting metabolic rate changes. However, aerobic training was shown to have a positive effect on all factors including body weight, body fat, and resting metabolic rate. In conclusion, DG ingestion and exercise training were not shown to have synergistic effects on resting metabolic rate changes, percent body fat and lipid profiles, while aerobic exercise training was shown to have a positive effect on resting metabolic rate changes, percent body fat, and lipid profiles. To investigate the therapeutic effect of DG ingestion and aerobic exercise for obese men, analysis of catecholamine, cAMP, HSL, or insulin sensitivity should be considered.

Multi-Round CPA on Hardware DES Implementation (하드웨어 DES에 적용한 다중라운드 CPA 분석)

  • Kim, Min-Ku;Han, Dong-Guk;Yi, Ok-Yeon
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.49 no.3
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    • pp.74-80
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    • 2012
  • Recently at SCIS2011, Nakatsu et. al. proposed multi-round Correlation Power Analysis(CPA) on Hardware Advanced Encryption Standard(AES) to improve the performance of CPA with limited number of traces. In this paper, we propose, Multi-Round CPA to retrieve master key using CPA of 1round and 2round on Hardware DES. From the simulation result for the proposed attack method, we could extract 56-bit master key using the 300 power traces of Hardware DES in DPA contes. And it was proved that we can search more master key using multi-round CPA than using single round CPA in limited environments.

Is Minimal Acupuncture an Adequate Control in Clinical Trials? (최소 침(Minimal Acupuncture)이 침 임상연구에서 적절한 대조군인가?)

  • Chae, Youn-Byoung;Kim, Song-Yi;Lee, Hye-Jung;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • v.25 no.2
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    • pp.71-85
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    • 2008
  • Objective : Acupuncture, one of the Oriental medical treatment techniques in East Asia, is growing in popularity all over the world. Based on bibliographical and clinical data, the depth of needling, i.e. superficial or deep needling, has been considered to be a variable as potential modifiers of needling effects, such as localization, manipulation of the needle, or elicitation of DeQi. The purpose of this review is to summarize clinical trials using minimal acupuncture and to evaluate its appropriateness as a control. Methods : A survey of computerized literature searches for randomized controlled trials using minimal acupuncture revealed that a total of 10 studies were published until April 2008. Results : Results obtained from clinical trials showed that acupuncture were more effective than minimal acupuncture in 3 out of 10 trials, while others were no more effective than control. However, minimal acupuncture might neither be a inert placebo nor be indiscriminable. Conclusion : Minimal acupuncture as 'placebo' controls seems misleading and scientifically unacceptable.

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DNA Barcoding of the Marine Protected Species Parasesarma bidens (Decapoda: Sesarmidea) from the Korean Waters

  • Kim, So Yeon;Yi, Chang Ho;Kim, Ji Min;Choi, Woo Yong;Kim, Hyoung Seop;Kim, Min-Seop
    • Animal Systematics, Evolution and Diversity
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    • v.36 no.2
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    • pp.159-163
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    • 2020
  • Parasesarma bidens(De Haan, 1835) has been designated as a marine protected species by the Act on conservation and management of marine ecosystems. This crab has been recorded only from Jeju-do and Geomun-do, Republic of Korea. In this study, we describe for the first time the mitochondrial cytochrome c oxidase subunit I(COI) sequences of P. bidens. The intra-specific genetic distance among the Korean populations and between the Korean and Chinese populations ranged from 0% to 0.9% and 1.9% to 2.7%, respectively. The inter-specific genetic distances among the four Parasesarma species ranged from 10.9% to 12.8%. The finding of this study will be helpful to better describe P. bidens using COI DNA barcodes and can be used as basic data for their restoration and conservation research.

Role of star formation and resulting properties from equal mass disk merger simulations

  • Ji, In-Chan;Peirani, Sebastien;Yi, Suk-Young
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.1
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    • pp.40.1-40.1
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    • 2012
  • In the hierarchical universe, galaxy merger is predicted to be frequent, and thus it is an important element for understanding galaxy evolution. In particular, star formation is greatly enhanced during the merger. The aim of this study is to understand the position and rate change of star formation caused by equal-mass edge-on mergers. We use the GADGET2- N-body/SPH code, and fully consider gas cooling, star formation, and supernova feedback. We show the star formation rate (SFR), and the magnitude and color evolution of the merger remnants for 18 different configurations varying orbit elements and inclinations of host galaxies against orbit planes. Then we construct the mock images of the remnants and investigate on how equal-mass galaxy merger affects the SFR and color/magnitude evolution while considering dust reddening. We conclude that over 90% mass of SF in equal-mass merger is in the central region. SF in tidal feature involves a small fraction of new stars and thus is difficult to detect unless deep imaging is performed. Around 55 ${\pm}$ 5 percent of gas turns into stars until the final coalescence which typically corresponds to 0.8, 1.2, and 2.5 Gyr for direct, parabolic, and elliptical orbit, respectively. This result is roughly consistent with Cox et al. 2000. We plan to implement this result into semi-analytic model of galaxy formation. Caveats and future work on merging conditions are discussed.

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Paracentric Inversions Found in Prenatal Diagnosis

  • Lee, Shin Yeong;Lee, Bom Yi;Park, Ju Yeon;Choi, Eun Young;Lee, Yeon Woo;Oh, Ah Rum;Ryu, Hyun Mee;Park, So Yeon
    • Journal of Genetic Medicine
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    • v.10 no.2
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    • pp.104-108
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    • 2013
  • Purpose: This study was designed to confirm whether the paracentric inversions of fetuses and parents may be harmless. Materials and methods: We report 10 cases (0.14%) with paracentric inversions among 7,181 prenatal cases observed during prenatal diagnosis performed at Cheil General Hospital between January 2009 and June 2013. We used cytogenetic GTL- and RBG-banding techniques. Results: Of the 10 cases, nine cases were transmitted from each of the parents, and one case was de novo. Nine cases were phenotypically normal up to one month of age after birth. One case was lost to follow-up. We present prenatal diagnosis and follow-up examination of the fetuses with paracentric inversion. Conclusion: Based on our cases, most paracentric inversions are considered to be harmless. The precise identification of paracentric inversions might be clinically important and helpful for genetic counseling.

SENP2 Regulates Hepatocellular Carcinoma Cell Growth by Modulating the Stability of β-catenin

  • Shen, Huo-Jian;Zhu, Hong-Yi;Yang, Chao;Ji, Fu
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3583-3587
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    • 2012
  • SUMOylation has emerged as an important post-translational modification that modulates the localization, stability and activity of a broad spectrum of proteins. A dynamic process, it can be reversed by a family of SUMO-specific proteases (SENPs). However, the biological roles of SENPs in mammalian development and pathogenesis remain largely elusive. Here, we demonstrated that SENP2 plays a critical role in the control of hepatocellular carcinoma cell growth. SENP2 was found to be down-regulated in hepatocellular carcinoma (HCC) tissues and over-expression suppressed the growth and colony formation of HCC cells. In contrast, silencing of SENP2 by siRNAs promoted cancer cell growth. We further found that stability of ${\beta}$-catenin was markedly decreased when SENP2 was over-expressed. Interestingly, the decrease was dependent on the de-SUMOylation activity of SENP2, because over-expression of a SENP2 catalytic mutant form had no obviously effects on ${\beta}$-catenin. Our results suggest that SENP2 might play a role in hepatocellular carcinoma cell growth control by modulating the stability of ${\beta}$-catenin.

TNM Stages and Prognostic Features of Colorectal and Mucinous Adenocarcinoma Patients: a Meta Analysis

  • Chen, Jing-Xiang;Tang, Xu-Dong;Xiang, De-Bing;Dong, Xiao-Ling;Peng, Fang-Yi;Sun, Gui-Yin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3427-3430
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    • 2012
  • Aim: The significance of the mucinous adenocarcinoma in TNM staging and prognosis for colorectal tumor patients is still controversial. The aim was to provide a meta-analysis for TNM staging and prognostic features of colorectal tumors. Methods: 30 individual case-control studies were finally included into this meta-analysis, involving a total of 444,489 cancer cases and 45,050 mucinous adenocarcinomas, of relations with TNM staging and prognostic features. Results: Compared to non-mucinous adenocarcinoma patients, the TNM IV stage accounted for a larger percentage of mucinous adenocarcinomas (OR=1.48, 95%CI 1.28-1.71, POR<0.001) and the prognosis was significantly poor (HR=1.06, 95%CI 1.04-1.08, P<0.001). After heterogeneity testing, the results was similar to the holistic approach outcome (HR=1.48, 95%CI 1.35-1.62, P<0.001). Conclusion: Compared to patients with non-mucinous adenocarcinomas, mucinous adenocarcinoma patients with later TNM staging make up a big percentage, and mucinous adenocarcinoma is an independent risk factor for poor prognosis.

EVALUATION OF SPEED AND ACCURACY FOR COMPARISON OF TEXTURE CLASSIFICATION IMPLEMENTATION ON EMBEDDED PLATFORM

  • Tou, Jing Yi;Khoo, Kenny Kuan Yew;Tay, Yong Haur;Lau, Phooi Yee
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2009.01a
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    • pp.89-93
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    • 2009
  • Embedded systems are becoming more popular as many embedded platforms have become more affordable. It offers a compact solution for many different problems including computer vision applications. Texture classification can be used to solve various problems, and implementing it in embedded platforms will help in deploying these applications into the market. This paper proposes to deploy the texture classification algorithms onto the embedded computer vision (ECV) platform. Two algorithms are compared; grey level co-occurrence matrices (GLCM) and Gabor filters. Experimental results show that raw GLCM on MATLAB could achieves 50ms, being the fastest algorithm on the PC platform. Classification speed achieved on PC and ECV platform, in C, is 43ms and 3708ms respectively. Raw GLCM could achieve only 90.86% accuracy compared to the combination feature (GLCM and Gabor filters) at 91.06% accuracy. Overall, evaluating all results in terms of classification speed and accuracy, raw GLCM is more suitable to be implemented onto the ECV platform.

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