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Effects of Acute Changes in the Energy and Protein Intake Levels over the Short-term on the Maternal Milk Amino Acid Concentrations in Lactating Mares

  • Matsui, A.;Inoue, Y.;Asai, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제18권6호
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    • pp.855-860
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    • 2005
  • This study was designed to test the effects of changes in energy and protein intake levels on the maternal milk amino acid concentrations over the short-term in lactating mares. Three lactating mares were enrolled for the study 7 weeks after parturition. A low-energy and low-protein diet (LEP) was administered during the first week of the study, followed by administration of a high-energy and high-protein diet (HEP), again for a week (day 1 to day 7), and milk was sampled thrice daily at intervals of 8 h during the study period. The mean amino acid concentrations in the maternal milk, except for those of proline, serine and valine, were significantly higher in the HEP feeding period than during the LEP feeding period (p<0.05). The sum of the concentrations of all the amino acids (TAA) in the maternal milk samples during the HEP and LEP feeding periods was 1,644.9${\pm}$26.9 and 1,542.3${\pm}$36.0 mg/100 g, respectively, the difference between the two was not significant. When the ratio of each amino acid concentration to the TAA in the maternal milk was analyzed, there were significant differences between the HEP and LEP feeding periods for all amino acids, except glycine, serine, alanine and histidine. It was found that the concentrations of glutamic acid+glutamine, serine, threonine, arginine and valine were significantly higher (p<0.05) on day 1 than on day 7 during the LEP feeding period, and there were no such differences during the HEP feeding period. In regard to the effects of changes in the energy and protein intake levels in lactating mares, no changes in milk amino acid concentrations were found following administration of HEP for a week, whereas 7 days of administration of LEP was associated with a decrease in the amino acid concentrations.

A Thirteen-week Oral Dose Subchronic Toxicity Study of Isaria sinclairii in Rats

  • Ahn, Mi-Young;Han, Jea-Woong;Jee, Sang-Deok;Hwang, Jae-Sam;Hwang, Seok-Jo;Hong, Yoo-Na;Kim, Sung-Nam
    • Toxicological Research
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    • 제23권4호
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    • pp.363-371
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    • 2007
  • Isaria sinelairii (IS) was orally administered at doses of 0, 0.04, 0.2, and 1 g/kg/day over a 13-week period. There were no observed clinical signs or deaths related to treatment in all the groups tested. Therefore, the approximate lethal oral dose of I. sinclairii was considered to be higher than 1 g/kg in rats. Throughout the administration periods, no significant changes in diet consumption, ophthalmologic findings, organ weight, clinical pathology (hematology, clinical chemistry, coagulation, and urinalysis) or gross pathology were detected. Minor changes were found in hematological parameters for the 0.04 g/kg/day and 0.2 g/kg/day IS treated groups (triglyceride reductions of $20.1{\sim}46.6%$ and platelet increases), but all changes were within physiological range. Microscopic examination failed to identify any treatment-related histopathologic changes in the organs of the IS-treated rats other than nuclear enlargement (cellular atypia) of the tubular regions in the medulla of the kidney in the high dose group. From these results, one can conclude that the no-observed effect level (NOAEL) of I. sinclairii is less than 0.04 g/kg/day in rats.

The Main and Interaction Effects of Day-care Experiences and Maternal Parenting Behavior on Preschoolers' Problem Behaviors (보육경험과 어머니의 양육행동이 유아의 문제행동에 미치는 주효과와 상호작용 효과)

  • Choi, Mi Na;Shin, Nana
    • Korean Journal of Childcare and Education
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    • 제11권2호
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    • pp.283-310
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    • 2015
  • The purpose of this study was to examine the main and interaction effects of day-care experiences and maternal parenting behavior on preschoolers' externalizing and internalizing problem behaviors. A total of 248 preschoolers(112 boys and 136 girls) and their mothers participated in this study. Mothers provided information about their children's day-care experiences(i.e., age of entry, hours per week, days per week, and number of day care centers attended by the preschoolers), their parenting behavior, and their children's problem behavior. Data were analyzed using correlations, multiple and hierarchical regressions, and post-hoc analysis suggested by Aiken and West(1991). First, preschoolers who frequently changed day-care centers showed higher levels of aggression. Second, maternal logical explanation, coercive and neglecting parenting behavior significantly influenced preschoolers' externalizing and internalizing problem behavior. Finally, interactions of day-care experiences and maternal parenting behavior were significant in predicting preschoolers' problem behavior. These findings suggest that day-care experiences need to be considered with other family variables in predicting preschoolers' developmental outcomes.

Effects of Aerobic Exercise Plus Lifestyle Modification Program on Obese-Induced Metabolic Syndrome in Obese Adolescent Girls (유산소운동과 생활양식 프로그램 병행이 비만 여자청소년의 비만유래 대사증후군에 미치는 효과)

  • Park, Chan-Ho;Park, Tae-Gon
    • Journal of Life Science
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    • 제19권2호
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    • pp.198-205
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    • 2009
  • The purpose of this study was to find out the effects of a 12-week aerobic exercise plus lifestyle modification on obese-induced metabolic syndrome in obese adolescent girls. A total of 52 obese adolescent girls (13-14 years old; body mass index (BMI) ${\geq}$95th percentiles for age and sex) purposely assigned to aerobic exercise group (AEG, n=15), aerobic exercise plus lifestyle modification group (ALG, n=18), or control group (CG, n=19). The AEG completed 12 weeks of walking exercise (30-60 min/day, 65-75% HRmax, 6 days/week), the ALG completed 12 weeks of walking exercise (30-60 min/day, 65-75% HRmax, 6 days/week) and behavior modification (60 min/day, 1 day/week), and the CG continued their normal life. The presence of the metabolic syndrome and component risk factors were determined before and after 12-week programs. The total prevalence of the metabolic syndrome was 48.1% in this sample (25/52) of participants at baseline. After the programs the prevalence of the metabolic syndrome was improved in the AEG and ALG 33.3, 27.8%, respectively. Group analyses showed significant difference in risk factors of the metabolic syndrome such that the AEG and ALG had significantly greater improvements in waist circumference, triglycerides, blood glucose and systolic blood pressure than the CG, while there were no significant difference in HDL cholesterol and diastolic blood pressure. Also there was no group difference between AEG and ALG in all measured metabolic risk factors after the programs. These results indicate that the positive changes of the ALG were not associated with lifestyle modification (behavior modification) but associated with aerobic exercise. However, long-term follow up studies are necessary to clarify the additive effect of the behavior modification on the metabolic syndrome.

Short-Term Load Forecasting using Relationship of Temperature and Load (온도와 부하의 관계를 이용한 단기부하예측)

  • Lee, Kyung-Hun;Lee, Yun-Ho;Kim, Jin-O;Lee, Hyo-Sang
    • Proceedings of the KIEE Conference
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    • 대한전기학회 2001년도 추계학술대회 논문집 전력기술부문
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    • pp.272-274
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    • 2001
  • This paper presents a model for short-term load forecasting using relationship of temperature and load. We made one-day ahead load forecasting model using hourly normalized load and 11 dummy variables that were classified by day characteristics such as day of the week, holiday, and special holiday.

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Acute Toxicity and Four-week Intravenous Toxicity Studies of Intralipidos (Intralipidos에 대한 급성독성 및 4주간 정맥 내 반복투여 독성시험)

  • Li, Guang-Xun;Che, Jeong-Hwan;Kang, Byeong-Cheol;Lee, Won-Woo;Ihm, Jong-Hee;Jung, Ji-Yun;Yi, Beoung-Hi;Nam, Jeong-Seok;Park, Jae-Hak;Lee, Yong-Soon
    • Toxicological Research
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    • 제14권3호
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    • pp.443-452
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    • 1998
  • This sutdy was carried out to investigate the acute toxicity and foru-week intravenous toxicity of the intralipidos in rats and rabbits. The acute toxicity study of Intralipidos was performed in Spragur-Dawley (SD) rats. Intralipidos was administered by intravenous to maximum dose 200 ml/kg. $LD_{50}$ of intralipidos was found 139.5ml/kg and 153.8ml/kg in male female SD rats. Four-week toxicity of intralipidos using New Zealand White Rabbit and SD rats. The Rabbit and Rats were administered by intravenous seven days per week for 28 days, with dosage of 15, 6, 2 ml/kg/day and 20, 6, 2ml/kg/day, respectively. Animals treated with intralipidos did not cause any death and show any clinical signs. They did not show any significant changes of body weight, feed uptake and water consumption. They were not significantly different from the control group in urinalysis, ocular examination hematological, serum biochemical value and histopathological examination. Therefore, Intralipidos was not indicated to have any toxic effect in the Rabbits and Rats, when it was administrated by intravenous below the dosage 15ml/kg/day and 20 ml/kg/day for four weeks.

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Effects of Nutrition Counseling on Diet and Nutritional Status of Cancer Patients on Radiotherapy (영양 상담이 방사선 치료를 받는 암환자의 식이 섭취와 영양 상태에 미치는 영향)

  • 백희영
    • Journal of Nutrition and Health
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    • 제33권2호
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    • pp.193-201
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    • 2000
  • This study was conducted to investigate the effectiveness of nutrition counseling on the dietary intake and nutritional status cancer patients undergoing radiotherapy treatment. The study was conducted over 6 week period and included 104 patients : 66 received nutrition counseling as the variable group of 42 male and 24 female and 38 patients received no counseling as the control group of 19 male and 19 female. Nutrition counseling was accompanied with the radiation therapy and adminstered via counseling session and distribution of printed material during radiation therapy for 6 weeks. Nutrition counseling aimed at maintaining a balanced diet and preventing weight loss of subjects, guideline used for energy and protein intake were 35kcal/kg IBW and 1.5-2.0g/kg IBW, respectively. Over the course of the study, the counseling group increased significantly in comparison to the control group's energy intake, evidenced by the counseling group's initial mean daily energy intake of 1932.0kcal, and 4 and 6 week mean energy intake values of 2046.6kcal, 2066kcal, respectively. But mean energy values of control group was 1614.3kcal at 4 week. Th energy intake per weight values and protein intake per weight values for initial, 4 and 6 week intervals for counseling group were 33.2kcal/kg, 33.7kcal/kg, 34.0kcal/kg, and 1.48g/kg, 1.58g/kg, 1.59g/kg, respectively. Based on results, nutrition counseling had positive effects on both the variety of diet and energy intake of the variable group, mostly due to an increase in dairy product and egg consumption. In addition, the percentage of counseling group patients who consumed all 5 food group increased from 48.5% to 54.5%. Sufficient energy intake and protein consumption seem to be important factors in weight loss prevention, evidenced by weight gain by subjects in the counseling group who had 36.1kcal/kg/day mean energy intake and 1.77g/kg/day mean protein intake after 4 weeks. Counseling group subjects experiencing weight loss had lower intake and 1.77g/kg/day mean protein intake after 3 weeks. Counseling group subjects experiencing weight loss had lower intakes of 29.3kcal/kg/day for energy and 1.33g/kg/day for protein during the same period. Another significant factor in weight loss prevention of the counseling group could be the variety of diet. The dietary variety scores(DVS) of both counseling and control groups differed significantly : the counseling group had a mean score of 34 while the control group of patients. At the end of the study, the mean percentage of subjects within each group having a DDS 5 was higher in the counseling group (54.5% v.s. 24.0%). In this study, nutrition counseling for cancer patients undergoing radiation therapy proved to be effective in preventing weight loss, a major complication during radiotherapy. Nutrition counseling not only increased protein and energy intake, but also had desirable effects on variety or diversity of diet.

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The Histologic Findings and the Expression of Laminin in the Mucosa of the Rat Trachea During (백서 기관 점막의$SO_2$ 노출 후 회복과정의 조직학적 관찰 및 laminin의 발현에 관한 연구)

  • Lee, Hyung-Seok;Tae, Kyung;Cho, Seok-Hyun;Han, Jang-Hee;Jeong, Jin-Suck
    • Korean Journal of Bronchoesophagology
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    • 제8권1호
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    • pp.29-34
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    • 2002
  • Background and Objectives : Sulfur dioxide gas is one of the major airborne Pollutants noxious to human in industrialized countries. The most vulnerable areas in the human respiratory system were the trachea and main bronchi and a gradient of decreasing damage was observed in the peripheral tracheobronchial tree. Induced functional alteration was increased mucosal permeability, and morphological changes were epithelial sloughing, intracellular edema, mitochondrial swelling, widened intercellular spaces, and ciliary cytoplamic extrusions. The laminins are a family of extracellular matrix glycoproteins localized in the basement membrane. Their primary role is cell-matrix attachment, but many additional biologic activities, including Promoting cell growth and migration, tumor growth and metastasis, wound repair, and graft survival, have been demonstrated. Materials and Methods : Histologic changes and expression of laminin in tracheal mucosa sacrificed at 1 day, 2 day, 3 day, 1 week, 2 weeks, and 3 weeks after continued SO2 exposure of 250 ppm for 30 minutes a day(to 7week) were studied in rats. In this study, mild immune reaction for laminin was noted at the apical cytoplasm of epithelial cells and basement membrane one day after a 7 week $SO_2$ exposure. The cilia and nucleoi of epithelial cells were normal and no immune reaction was noted in Goblet cells. The lamina propria of the tracheal tissue was infiltrated by monocytes and lymphocytes. Results : At 24 hours after exposure, all tracheal cells except Goblet cells revealed a mild immune reaction for laminin. No immune reactions were noted in the basement membrane. At 72 hours after exposure, mild or moderate immune reactions for laminin was seen in the tracheal cell cytoplasm. Irregular faint immune reaction for laminin was noted in the basement membrane. At 1 week after exposure, strong immune reaction for laminin was detected over all tracheal cells, and the basement membrane was seen clearly. At 2~3 weeks after exposure, strong immune reaction for laminin was seen in all tracheal epithelial cells except Goblet cells and a mild immune reaction was partly revealed in the basement membrane. Conclusion : Our study suggests that 502 produces histologic damage on the tracheal mucosa. Longer duration after exposure of $SO_2$ makes more progressive healing on the tracheal mucosa and increased immunoreactivity for laminin.

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Clinical study of Slim Cushion on the decrease effect of the girth of the lower half of body (슬림 큐션의 하반신 둘레 감소에 대한 임상적인 연구)

  • Kim Gyeang Cheal;Hwang Won Deuk
    • Journal of Physiology & Pathology in Korean Medicine
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    • 제18권3호
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    • pp.854-856
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    • 2004
  • The purpose of this study was to investigate the effects of Slim Cushion on the decrease of the girth of the lower half of body. We used Slim Cushion for health appliance of woman's hypogastrium. We collected 30 woman patients with obesity and then expremented Slim Cushion 15 mintues × 3 times I day, during 12 weeks. We checked the weight of body, the girth of navel and pelvis and thigh for every week. The results were as follows: The decrease of weight was not significant. The decrease of navel girth was significant change 3, 4, 5, 6, 7, 8 week times (p<0.05) and very significant 9, 10, 11, 12 week times. The decrease of pelvis girth was significant change 4, 5, 6, 7, 8 week times (p<0.05) and very significant 9, 10, 11, 12 week times(p<0.01). The decrease of thigh girth was significant change 6, 7, 8, 9, 10, 11 week times (p<0.05) and very significant 12 week times(p<0.01).

The Determinants of Health Promoting Behavior of Industrial Workers (산업장 근로자의 건강증진행위와 자아개념 및 건강의 중요성 인식에 관한 연구)

  • Kim, Chung Nam
    • Korean Journal of Occupational Health Nursing
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    • 제7권1호
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    • pp.5-19
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    • 1998
  • This descriptive-correlational study was conducted to identify the major factors affecting health promoting behaviors. 344 workers who employed in four different manutacturing plants in Taegu and Kyungbuk area were selected by convenience sampling method. Data were collected from April let to April 18th, 1998 by ready structured questionaires. The purpose of this study was to offer the basic data for health promotion theory development and health promotion strategy planning. This study was based on Pender's Health Promotion Model and examined three variables health promoting behavior, self-concept and perceived importance of health. The Life Style and Health Habit Assessment scale(LHHA) developed by Pender(1982).The Self-concept scale developed by Choi(1972) and the Health Value scale developed by Wallston, Maides and Wallston(1980) were used for this study. Data was analyzed by percentage, mean. t-test. ANOVA, Pearson Correlation Coefficient, and Stepwise Multiple Regression. The major findings of this study are as follows ; 1. The average level of health promoting behavior practice was 63.2% and possible range was from 62 to 248 point. The mean score of respondent's positive self-concept was 75.8. 81.4% of respondents put a high priority on the importance of health. 2. There was a significant difference between the practice level in the category of general self care and less amount of working hours per day(P=0.000), less amount of working hours per week(P=0.000). There was a significant difference between the practice level in the category of nutrition and age(0.002), marital status(0.000), working hour per day(0.008), working hours per week(0.001), There was a significant difference between the practice level in the category of nutriton and sex(0.000), age(0.000), marital status(0.025), education level(0.000), working hours per day(0.002), working hours per week(0.006). There was a significant difference between the practice level in the category of sleep and rest and age(0.003), marital status(0.002), working hours per day(0.001), working hours per week(0.001). There was a significant difference between the practice level in the category of stress management and working hours per day(0.001), working hours per week(0.002). There was a significant difference between the practice level in the category of self-actualization and working hours per day(0.050). 3. General characteristics influencing the respodent's self-concept were level(P=0.009) and worksite(P=0.001). 4. The results of the hypothesis tests are as follows The first hypothesis, that "The respondent who have more positive self-concept will have higher scores in the practice of health promoting behavior." was supported(r=0.2973, P=0.0001). The second hypothesis that "The respondent who have higher perception level on importance of health will have higher scores in the practice health promoting behavior." was rejected(r=- 0665, P=0.2225). 5. The most important factor that affects health promoting behavior practice was working hours per week(6.0%). The combination of working hours per week, age, education level accounted for 10.0% of the variance in health promoting behavior. In conclusion, the results of this study on industrial workers supported Pender's health promotion model in partial and showed the relatedness between self concept and the practice of health promoting behavior. Further research is required to find factors influencing health promoting behaviors of industrial workers.

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