• 문화기술의 융합
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• 제10권2호
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• pp.493-498
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• 2024

최근 생성형 인공지능 기술이 급속도로 발전함에 따라, 이를 실무에 활용하는 방법에 대한 관심이 높아지고 있다. 또한 사용자 요구에 부합하는 결과물을 생성하기 위한 프롬프트 엔지니어링의 중요성이 새롭게 조명되고 있다. 이러한 생성형 인공지능의 새로운 활용 가능성을 탐구하는 것은 중요한 가치를 지닐 수 있다. 본 연구는 대표적인 생성형 인공지능인 챗지피티 4.0을 활용하여 온라인 고객 리뷰 데이터 분석을 통한 효과적인 사용자 경험 평가 방법을 제안하는 것을 목적으로 한다. 사용자 경험 평가 방법은 사용자 경험 계층의 6단계 요소인 '기능성', '신뢰성', '사용성', '편의성', '감성', '의미성'을 기반으로 수행되었다. 본 연구를 위해 프롬프트 엔지니어링의 이해도를 높이고 사용자경험 계층의 명확한 개념을 파악하는 문헌연구를 수행하고, 이를 기반으로 프롬프트를 작성 및 수집된 온라인 고객 리뷰 데이터 분석을 통한 사용자 경험 평가 방법을 위한 실험이 수행되었다. 본 연구에서 우리는 사용자 경험 요소에 대한 정확한 정의 및 분류 과정에 대한 설명 입력 시, 챗지피티는 사용자 경험 평가에 대한 우수한 성능을 나타냈으나, 시간적 제약으로 다량의 데이터 분석에 한계를 나타냈음을 밝힌다. 우리는 사용자 경험 평가에 챗지피티 4.0을 활용하는 방법을 소개하고 제안함으로써 UX 분야의 발전에 공헌할 수 있는 것으로 기대한다.

• Molecules and Cells
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• 제47권3호
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• pp.100033.1-100033.13
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• 2024

Considering the recent increase in the number of colorectal cancer (CRC) cases in South Korea, we aimed to clarify the molecular characteristics of CRC unique to the Korean population. To gain insights into the complexities of CRC and promote the exchange of critical data, RNA-sequencing analysis was performed to reveal the molecular mechanisms that drive the development and progression of CRC; this analysis is critical for developing effective treatment strategies. We performed RNA-sequencing analysis of CRC and adjacent normal tissue samples from 214 Korean participants (comprising a total of 381 including 169 normal and 212 tumor samples) to investigate differential gene expression between the groups. We identified 19,575 genes expressed in CRC and normal tissues, with 3,830 differentially expressed genes (DEGs) between the groups. Functional annotation analysis revealed that the upregulated DEGs were significantly enriched in pathways related to the cell cycle, DNA replication, and IL-17, whereas the downregulated DEGs were enriched in metabolic pathways. We also analyzed the relationship between clinical information and subtypes using the Consensus Molecular Subtype (CMS) classification. Furthermore, we compared groups clustered within our dataset to CMS groups and performed additional analysis of the methylation data between DEGs and CMS groups to provide comprehensive biological insights from various perspectives. Our study provides valuable insights into the molecular mechanisms underlying CRC in Korean patients and serves as a platform for identifying potential target genes for this disease. The raw data and processed results have been deposited in a public repository for further analysis and exploration.

• Korean Journal of Radiology
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• 제21권12호
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• pp.1345-1354
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• 2020

Objective: To evaluate radiomics analysis in studies on mild cognitive impairment (MCI) and Alzheimer's disease (AD) using a radiomics quality score (RQS) system to establish a roadmap for further improvement in clinical use. Materials and Methods: PubMed MEDLINE and EMBASE were searched using the terms 'cognitive impairment' or 'Alzheimer' or 'dementia' and 'radiomic' or 'texture' or 'radiogenomic' for articles published until March 2020. From 258 articles, 26 relevant original research articles were selected. Two neuroradiologists assessed the quality of the methodology according to the RQS. Adherence rates for the following six key domains were evaluated: image protocol and reproducibility, feature reduction and validation, biologic/clinical utility, performance index, high level of evidence, and open science. Results: The hippocampus was the most frequently analyzed (46.2%) anatomical structure. Of the 26 studies, 16 (61.5%) used an open source database (14 from Alzheimer's Disease Neuroimaging Initiative and 2 from Open Access Series of Imaging Studies). The mean RQS was 3.6 out of 36 (9.9%), and the basic adherence rate was 27.6%. Only one study (3.8%) performed external validation. The adherence rate was relatively high for reporting the imaging protocol (96.2%), multiple segmentation (76.9%), discrimination statistics (69.2%), and open science and data (65.4%) but low for conducting test-retest analysis (7.7%) and biologic correlation (3.8%). None of the studies stated potential clinical utility, conducted a phantom study, performed cut-off analysis or calibration statistics, was a prospective study, or conducted cost-effectiveness analysis, resulting in a low level of evidence. Conclusion: The quality of radiomics reporting in MCI and AD studies is suboptimal. Validation is necessary using external dataset, and improvements need to be made to feature reproducibility, feature selection, clinical utility, model performance index, and pursuits of a higher level of evidence.

• 한국음향학회지
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• 제43권1호
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• pp.78-88
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• 2024

수중 소음 측정이 가능한 수동 소나에 수신된 선박 방사소음은 Detection of Envelope Modulation on Noise(DEMON) 분석으로 얻은 선박 정보를 사용하여 선박 식별과 분류가 가능하다. 하지만 낮은 신호대잡음비(Signal-to-Noise Ratio, SNR) 환경에서는 DEMON 그램 내 선박 정보가 담겨있는 표적 주파수선을 분석 및 파악하는데 어려움이 발생한다. 본 논문에서는 낮은 SNR 환경에서 보다 정확한 표적 식별을 위해 딥러닝 기법 중 의미론적 분할을 사용하여 표적 주파수선들을 추출하는 연구를 수행하였다. SNR과 기본 주파수를 변경시키며 생성한 모의 DEMON 그램 데이터를 사용하여 의미론적 분할 모델인 U-Net, UNet++, DeepLabv3+를 학습 후 평가하였고, 학습된 모델들을 이용하여 캐나다 조지아 해협에서 측정한 선박 방사소음 데이터셋인 DeepShip으로 제작한 DEMON 그램 예측 성능을 비교하였다. 모의 DEMON 그램으로 학습된 모델을 평가한 결과 U-Net이 성능이 가장 높았으며, DeepShip으로 만든 DEMON 그램의 표적 주파수선을 어느 정도 추출할 수 있는 것을 확인하였다.

• BMB Reports
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• 제57권3호
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• pp.161-166
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• 2024

Aberrant DNA methylation plays a critical role in the development and progression of colorectal cancer (CRC), which has high incidence and mortality rates in Korea. Various CRC-associated methylation markers for cancer diagnosis and prognosis have been developed; however, they have not been validated for Korean patients owing to the lack of comprehensive clinical and methylome data. Here, we obtained reliable methylation profiles for 228 tumor, 103 adjacent normal, and two unmatched normal colon tissues from Korean patients with CRC using an Illumina Infinium EPIC array; the data were corrected for biological and experiment biases. A comparative methylome analysis confirmed the previous findings that hypermethylated positions in the tumor were highly enriched in CpG island and promoter, 5' untranslated, and first exon regions. However, hypomethylated positions were enriched in the open-sea regions considerably distant from CpG islands. After applying a CpG island methylator phenotype (CIMP) to the methylome data of tumor samples to stratify the CRC patients, we consolidated the previously established clinicopathological findings that the tumors with high CIMP signatures were significantly enriched in the right colon. The results showed a higher prevalence of microsatellite instability status and MLH1 methylation in tumors with high CMP signatures than in those with low or non-CIMP signatures. Therefore, our methylome analysis and dataset provide insights into applying CRC-associated methylation markers for Korean patients regarding cancer diagnosis and prognosis.

• 아태비즈니스연구
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• 제14권4호
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• pp.67-85
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• 2023

Purpose - This study seeks to investigate the determinants of global sourcing intention in clothing sewing industry, in particular with its focus on women's knit wear production. Design/methodology/approach - This study collected a unique set of qualitative data through 31 in-depth interviews with fashion brands, promotion agencies, and sewing factories between July 2023 and October 2023. In addition, it analyzed the dataset using the MAXQDA to complement the research findings. Findings - We have two findings. First, the interviewees commonly mentioned the following factors as reasons for considering global sourcing: the human factors(aging of skilled technicians and labor shortages), the financial factors(gap in production unit prices at home and abroad), the relational factors(lack of novelty), and the physical factors(loss of production infrastructure and network), while the human factors(skilled workforce), the production factors(delivery date and product quality), and the relational factors(timely communication and mutual trust) as reasons for continuing domestic sourcing. Additional code analysis of interview also supports this finding. On the other hand, there was also a subtle difference between buyers(brands) and suppliers(promotion agencies and processing plants), and buyers consider the exact delivery date critical so that they could see trend-sensitive women's knit wear on time, and suppliers took production costs, labor costs, and labor shortages, which are financial factors, more seriously. Research implications or Originality - This study provides a richer and more balanced view of existing literature, which has generally tended to introduce global sourcing across the clothing industry despite the existence of various diversity within the industry. In addition, through qualitative research, we introduce that the sewing industry is carried out according to complex factors, and by revealing and categorizing the determinants of global sourcing, we supplement the existing research on the clothing sewing industry centered on survey. On a practical note, this study introduces that there is a difference in view of domestic sourcing and global sourcing between buyers(brands) and suppliers(promotion agencies and sewing factories), suggesting practical implications for revitalizing networks and deriving win-win cooperation network models among members in the future.

• 한국지리정보학회지
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• 제27권1호
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• pp.81-98
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• 2024

본 연구는 시민들이 직접 체감하는 더위인 체감더위를 열환경 단위로 설정하여 공간적 요인과의 상관관계를 분석하고 체감더위 예측 모형을 개발하였다. 체감더위를 수집하기 위해 리빙랩이라는 시민 참여형 연구방법론을 적용하여 시민들이 직접 체감더위를 기록하고 주변의 온도를 측정하도록 하였다. 수집한 체감더위 정보의 입력지점에 기반하여 주변 도시공간적 요소를 수집하여 통계 분석을 위한 데이터셋을 구축하였다. 구축한 데이터를 활용하여 로지스틱 회귀분석을 수행하였다. 분석 결과, 기온은 주변 공간환경에 영향을 받으며, 건물 높이, 녹지율, 도로율과 음의 상관관계를 가지고, 기온과 천공률과 양의 상관관계를 가진다고 분석되었다. 또한 도로율, 천공률, 녹지율 순으로 체감더위에 강한 영향을 미치는 것으로 나타났다. 본 연구의 결과는 기후변화 대응을 위한 국지적인 열환경 대책을 마련하기 위한 열환경 평가의 기초자료로 활용될 수 있을 것으로 기대된다.

• 한국지구과학회지
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• 제45권3호
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• pp.192-202
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• 2024

해양재분석 자료는 관측 자료를 수치 모델에 동화함으로, 관측 자료의 시공간적인 제약을 극복하고 해양 변수 간의 물리적 상호작용을 고려한 격자화된 고해상도 정보를 제공함으로써 해양순환 및 기후 연구에 광범위하게 사용되고 있다. 이 연구에서는 기존에 생산된 12년간(2011년부터 2022년까지)의 북서태평양 지역해양 재분석 자료를 확장하여 30년간(1993년부터 2022년까지)의 1/24° 수평해상도를 갖는 장기 재분석 자료(K-ORA22E)를 생산하고, 이를 분석하여 한반도 주변해역에서의 장기 해양기후변화를 진단하였다. K-ORA22E 데이터를 통해 한반도 주변 해역의 수온 상승 경향을 분석한 결과, 쿠로시오 확장역에서 쿠로시오의 경로가 지난 30년 동안 1년에 약 6 km 씩 북상하였으며, 쿠로시오 경로의 북쪽에서 수온 상승이 두드러졌다. 한반도 주변 해역 중에서는 동해에서 수온 상승이 가장 뚜렷했다. 특히, 동해에서는 표층보다는 중층에서 수온 상승이 두드러졌으며, 동한난류의 수온 상승률은 전 지구 평균보다 2-3배 높았다. 황해저층냉수가 출현하는 황해 중앙부에서는 장기적으로 수온이 상승하였으나, 한반도 서해안과 남해안에서는 수온이 오히려 감소하는 경향이 나타났다. 이러한 수온의 장기변화의 공간적인 차이는 쿠로시오 해류의 북상에 따른 열수송의 경로와 밀접한 관련이 있을 것으로 보인다. 이 연구에서 구축된 K-ORA22E와 같은 고해상도 지역 해양 재분석 자료는 한반도 주변 해역의 장기 변동성을 이해하고 기후 변화의 영향을 분석하는 데 중요한 기초 자료로 활용될 수 있을 것이다.

• Journal of Gastric Cancer
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• 제24권3호
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• pp.341-352
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• 2024

Purpose: Textbook outcome is a comprehensive measure used to assess surgical quality and is increasingly being recognized as a valuable evaluation tool. Delta-shaped anastomosis (DA), an intracorporeal gastroduodenostomy, is a viable option for minimally invasive distal gastrectomy in patients with gastric cancer. This study aims to evaluate the surgical outcomes and calculate the textbook outcome of DA. Materials and Methods: In this retrospective study, the records of 4,902 patients who underwent minimally invasive distal gastrectomy for DA between 2009 and 2020 were reviewed. The data were categorized into three phases to analyze the trends over time. Surgical outcomes, including the operation time, length of post-operative hospital stay, and complication rates, were assessed, and the textbook outcome was calculated. Results: Among 4,505 patients, the textbook outcome is achieved in 3,736 (82.9%). Post-operative complications affect the textbook outcome the most significantly (91.9%). The highest textbook outcome is achieved in phase 2 (85.0%), which surpasses the rates of in phase 1 (81.7%) and phase 3 (82.3%). The post-operative complication rate within 30 d after surgery is 8.7%, and the rate of major complications exceeding the Clavien-Dindo classification grade 3 is 2.4%. Conclusions: Based on the outcomes of a large dataset, DA can be considered safe and feasible for gastric cancer.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제27권4호
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• pp.206-214
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• 2024

Purpose: Few studies have reported the prevalence of inflammatory bowel disease unclassified (IBDU) among Korean pediatric IBD (PIBD) population. To address this gap, we used two tertiary centers and nationwide population-based healthcare administrative data to estimate the prevalence of Korean pediatric IBDU at the time of diagnosis. Methods: We identified 136 patients aged 2-17 years with newly diagnosed IBD (94 Crohn's disease [CD] and 42 ulcerative colitis [UC]) from two tertiary centers in Korea between 2005 and 2017. We reclassified these 136 patients using the revised Porto criteria. To estimate the population-based prevalence, we analyzed Korean administrative healthcare data between 2005 and 2016, which revealed 3,650 IBD patients, including 2,538 CD and 1,112 UC. By extrapolating the reclassified results to a population-based dataset, we estimated the prevalence of PIBD subtypes. Results: Among the 94 CD, the original diagnosis remained unchanged in 93 (98.9%), while the diagnosis of one (1.1%) patient was changed to IBDU. Among the 42 UC, the original diagnosis remained unchanged in 13 (31.0%), while the diagnoses in 11 (26.2%), 17 (40.5%), and one (2.4%) patient changed to atypical UC, IBDU, and CD, respectively. The estimated prevalences of CD, UC, atypical UC, and IBDU in the Korean population were 69.5%, 9.4%, 8.0%, and 13.1%, respectively. Conclusion: This study is the first in Korea to estimate the prevalence of pediatric IBDU. This prevalence (13.1%) aligns with findings from Western studies. Large-scale prospective multicenter studies on PIBDU are required to examine the clinical features and outcomes of this condition.