• Title/Summary/Keyword: Data-science

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Antiproliferative Effect of Extracts, Fractions and Compound from Vitex rotundifolia on Human Cancer Cells (순비기 나무(Vitex rotundifolia) 추출.분획물 및 화합물의 인체 암세포 증식억제 효과)

  • Kim, You-Ah;Lee, Jung-Im;Kim, Hae-Jin;Kong, Chang-Suk;Nam, Taek-Jeong;Seo, Young-Wan
    • Journal of Applied Biological Chemistry
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    • v.52 no.4
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    • pp.180-186
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    • 2009
  • Whole plants of Vitex rotundifolia were extracted for 2 days with methylene chloride ($CH_2Cl_2$) followed by extraction of the residue for an additional 2 days. The same procedure was also applied using methanol (MeOH). The two crude extracts were combined and partitioned between $CH_2Cl_2$ and $H_2O$. The organic layer was further partitioned between n-hexane and 85% aq. MeOH, and the aqueous layer was also further fractionated with n-BuOH and $H_2O$, successively. From the 85% aq. MeOH fraction, one compound was isolated through the repeated HPLC. According to the results of physicochemical data including NMR and MS, the chemical structure of the compound was determined as artemetin (1). The antiproliferative effects of the crude extracts, fractions, and compound against HT1080, AGS, MCF-7 and HT-29 human cancer cells were compared with the control by using MTT assay. In the comparative analysis, the 85% aq. MeOH fraction exhibited the strongest antiproliferative effects on human cancer cell lines in a dose-dependent manner (p<0.05). In addition, exposure of compound 1 isolated from 85% aq. MeOH fraction led to strong antiproliferative effect in HT1080 cancer cell lines. These results suggest that the extracts and compound isolated from V. rotundifolia may be used as potential chemopreventive and chemotherapeutic agents.

The Effects of Supplementation of Ascidian Tunic Shell into Laying Hen Diet on Egg Quality (산란계 사료에서 우렁쉥이껍질 첨가가 계란 품질에 미치는 영향)

  • Kim, E.Mi.
    • Journal of Animal Science and Technology
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    • v.44 no.1
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    • pp.45-54
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    • 2002
  • This study was conducted to evaluate the feeding value of ascidian tunic shell the effects of its dietary supplementation on laying performance, egg-yolk pigmentation, egg-shell strength and egg taurine content. A total of 168 brown layers at the age of 29wks in commercial cage were fed for 4 wks with 7 different diets containing ascidian tunic shel1(AST) at varying levels of 0$\sim$5% Dm or 0% AST with 100ppm carophyll red. No differences were found in egg production and weight among the treatments indicating that ascidian tunic shell did not adversely affect the laying performances. Adding the ascidian tunic shell to the diets increased egg-yolk pigmentation compared to the control and resulted in simillar or better effect on egg-yolk pigmentation compared to 100ppm carophyll red. The data suggest that ascidian tunic shell may be used as feed ingredients in layer diet enrichment of egg-yolk pigmentation in the place of carophyll red(chemical pigment). Specific gravity and breaking strength of egg shell were significantly increased by the adding ascidian tunic shell to the diet, suggesting that ascidian tunic shell may be used as feed ingredients for increasing egg shell strength. Also taurine content of egg was significantly increased with increasing supplementation of ascidian tunic shell to the diet(p<0.05). Therefore, ascidian tunic shell may be used as feed ingredients in laying hen diet to improve egg quality such as egg-yolk pigmentation, egg-shell strength and egg taurine enrichment.

Relationship Between Ultrasonic and Carcass Measures for Meat Qualities in Hanwoo Steers (한우 거세우에 있어서 생체단층조사기법에 의한 육질판정과 도축 육질 측정치와의 관계)

  • Kim, H. C.;Lee, D. H.;Choi, S. B.;Jeon, G. J.
    • Journal of Animal Science and Technology
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    • v.45 no.2
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    • pp.183-190
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    • 2003
  • Data from live animal real time ultrasound (RTU) measures from 127 Hanwoo steers were used to assess nutritional physiology and relationship between RTU measures and real carcass measures represented meat quality. Traits considered were longissimus muscle area, fat thickness, and marbling score imaged and scanned using RTU by month and those of carcass measures at about 24 month of age. On this study, increasing pattern for longissimus muscle area would be closely related to growth pattern (p<0.01) and it of fat thickness would be related to quadratic effect of ages. Marbling score would be related to aging, that is, individual deviates of scores were distinctly characterized after 17 mo. even though they were started at about 11 mo. Correlation estimates between RTU measures and corresponding carcass traits were over 0.6 after 17 month of age for all traits considered and these estimates were high as 0.90 after 22 month of age. From this study, Real-time ultrasound measurement would be valuable after 15-17 mo. and measures at about 22 mo. would be helpful to decide age for slaughtering. To utilize these techniques for beef cattle breeding via progeny testing program, 15 mo. RTU measures would be efficiency rather than 12 mo. of other beef breeds. Further study to find genetic variation of RTU measures was needed to utilize these technologies for beef breeding.

Comparison and Decision of Exposure Coefficient for Calculation of Snow Load on Greenhouse Structure (온실의 적설하중 산정을 위한 노출계수의 비교 및 결정)

  • Jung, Seung-Hyeon;Yoon, Jae-Sub;Lee, Jong-Won;Lee, Hyun-Woo
    • Journal of Bio-Environment Control
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    • v.24 no.3
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    • pp.226-234
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    • 2015
  • To provide the data necessary to determine exposure coefficients used for calculating the snow load acting on a greenhouse, we compared the exposure coefficients in the greenhouse structure design standards for various countries. We determined the exposure coefficient for each region and tried to improve on the method used to decide it. Our results are as follows: After comparing the exposure coefficients in the standards of various countries, we could determine that the main factors affecting the exposure coefficient were terrain roughness, wind speed, and whether a windbreak was present. On comparing national standards, the exposure coefficients could be divided into three groups: exposure coefficients of 0.8(0.9) for areas with strong winds, 1.0(1.1) for partially exposed areas, and 1.2 for areas with dense windbreaks. After analyzing the exposure coefficients for 94 areas in South Korea according to the ISO4355 standard, all of the areas had two coefficients (1.0 and 0.8), except Daegwallyeong (0.5) and Yeosu (0.6), which had one coefficient each. In South Korea, the probability of snow is greater inland than in coastal areas and there are fewer days with a maximum wind velocity > $5m{\cdot}s^{-1}$ inland. When determining the exposure coefficients in South Korea, we can subdivide the country into three regions: coastal areas with strong winds have an exposure coefficient of 0.8; inland areas have a coefficient of 1.0; and areas with dense windbreaks have an exposure coefficient of 1.2. Further research that considers the number of days with a wind velocity > $5m{\cdot}s^{-1}$ as the threshold wind speed is needed before we can make specific recommendations for the exposure coefficient for different regions.

Irrigation Control for Improving Irrigation Efficiency in Coir Substrate Hydroponic System (코이어 배지 수경재배에서 관수효율 향상을 위한 급액 제어)

  • Yoo, Hyung-Joo;Choi, Eun-Young;Lee, Yong-Beom
    • Journal of Bio-Environment Control
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    • v.24 no.3
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    • pp.153-160
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    • 2015
  • The objectives of this study were to determine optimal length of off-time between irrigation cycles to improve irrigation efficiency using a frequency domain reflectometry (FDR) sensor-automated irrigation (FAI) system for tomato (Solanum lycopersicum L.) cultivation aimed at minimizing effluent from coir substrate hydroponics. For treatments, the 5-minute off-time length between 3-minute run-times (defined as 3R5F), 10-minute off-time length between 3-minute run-times (defined as 3R10F), or 15-minute off-time length between 5-minute run-times (defined as 5R15F) were set. During the 3-minute or 5-minute run-time, a 60mL or 80mL of nutrient solution was irrigated to each plant, respectively. Until 62 days after transplant (DAT) during the autumn to winter cultivation, daily irrigation volume was in the order of 3R5F (858mL) > 5R15F (409mL) > 3R10F (306mL) treatment, and daily drainage ratio was in the order of 3R5F (44%) > 5R15F (23%) > 3R10F (14%). Between 63 and 102 DAT, daily irrigated volume was in the order of 5R15F (888mL) > 3R5F (695mL) > 3R10F (524mL) with the highest drainage ratio, 19% (${\pm}2.6$), at the 5R15F treatment. During the spring to summer cultivation, daily irrigation volume and drainage ratio per plant was higher in the 3R5F treatment than that of the 3R10F treatment. For both cultivations, a higher water use efficiency (WUE) was observed under the 3R10F treatment. Integrated all the data suggest that the optimal off-time length is 10 minutes.

Study on the correlation between nutrition knowledge, dietary attitudes of guardians, and nutritional status of infants and toddlers - Nutrition-Plus program in Jeonju (보호자의 영양지식 및 식생활태도와 영유아의 영양상태와의 관계연구 - 전주지역 영양플러스 참여자를 중심으로)

  • Song, Eun Young;Rho, Jeong Ok
    • Journal of Nutrition and Health
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    • v.51 no.3
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    • pp.242-253
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    • 2018
  • Purpose: The purpose of the study was to identify the nutrition knowledge, dietary attitudes of guardians, and nutritional status of infants and toddlers as well as the relationships between these variables. Methods: The participants were selected among applicants for low-income family financing provided by the government and included 115 infants and toddlers as well as their guardians. Demographic data, nutrition knowledge, dietary attitudes, and nutrition intakes were assessed using a self-administered questionnaire, biochemical examination, and 24 Hour-Recall method. Results: The score for guardians' nutrition knowledge was 12.97 points of a possible 15, and the score for dietary attitudes was 53.38 points of a possible 75. The nutrition knowledge and dietary attitudes showed significant differences by education level (p < 0.05) and family structure (p < 0.05). Energy intakes of subjects aged 6 ~ 24 months and over 25 months were lower than the DRI for Koreans. The intakes of carbohydrates, protein, and fat of subjects aged 6 ~ 24 months and over 25 months showed no significant differences by level of nutrition knowledge or dietary attitudes. The intake of Ca of subjects aged over 12 months showed significant differences by level of nutrition knowledge (p < 0.05). The intakes of Thiamin of subjects aged 6 ~ 11 months and P of subjects aged over 12 months showed significant differences by level of dietary attitudes (p < 0.05). There was a small positive correlation between education level and nutrition knowledge as well as between dietary attitudes. Nutrition knowledge showed a positive correlation with dietary attitudes. There was a positive correlation between nutrition knowledge and Ca, Riboflavin, as well as Vit C levels. Conclusion: Therefore, it is necessary to consider an educational program for increasing the practical application of knowledge to nutrition management for improvement of nutrition intake in infants and toddlers.

Optical Properties of Sea Water in Sagami Bay, Japan (일본 상모만에서의 해수의 광학적 성질)

  • YANG Yong-Rhim
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.20 no.2
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    • pp.119-125
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    • 1987
  • Optical properties of sea water were studied in the Sagami Bay, Japan, based on the data obtained from six oceanographic stations in June, 1985. The observation of surface irradiance and underwater irradiance of sea water for eight kind of wavelengths (378, 422, 481, 513, 570, 621, 653, 677 nm) of sun light was conducted using the underwater irradiameter $(Isigawa\;\#\;SR-8)$. The mean attenuation coefficient of the sea water was appeared to be 0.166 $(0.061\~0.644)$ and the attenuation coefficient of the sea water for wavelength appeared such as 0.121 for 378 nm, 0.105 for 422 nm, 0.097 for 481 nm, 0.099 for 513 nm, 0.138 for 570 nm, 0.253 for 621 nm, 0.258 for 653 nm, 0.253 for 677 nm. The transparency was 12.9 m $(7.2\~18m)$, water color was $(5\~10m)$ in the study area and the sun altitude was $70.79^{\circ}\;(57.44^{\circ}\~78.42^{\circ}C)$ The relationship between attenuation coefficient (K) ana transparency (D) was $K=2.87/D(1.06/D\~5.48/D)$. The rates of light penetration for eight kind of wavelenths (378, 422, 481, 513, 570, 621, 653, 677 nm) were computed with reference to the surface light intensity respectively, The mean rate of light penetration in proportion to depths were $77.93\%\;(52.52\~94.06\%)$ in 1 m layer, $35.46\%\;(4.00\~73.64\%)$ in 5m layer, $18.71\%\;(0.24\~54.23\%)$ in 10m layer and $7.00\%\;(0.007\~27.58\%)$in 20m layer. The rate of light penetration at the transparency layer with reference to the surface light intensity was shown as $13.02\%\;(0.42\~34.78\%)$.

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Breakfast Consumption Pattern, Diet Quality and Health Outcomes in Adults from 2001 National Health and Nutrition Survey (2001년 국민건강영양조사에 나타난 아침식사유형에 따른 식사의 질과 건강상태)

  • Shim, Jae-Eun;Paik, Hee-Young;Moon, Hyun-Kyung
    • Journal of Nutrition and Health
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    • v.40 no.5
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    • pp.451-462
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    • 2007
  • This study was conducted to investigate breakfast consumption pattern in relation to diet quality and health outcomes of Korean adults. Data are from 2001 National Health and Nutrition Survey. Dietary information of 3406 adults aged $30{\sim}49$ years and their socio-demographic characteristics, blood lipid profile, fasting blood glucose, blood pressure, anthropometric measurements were analyzed. According to the breakfast consumption of the subjects, they were classified to breakfast skippers and eaters and the eaters' breakfast staple types were defined as RICE, BREAD, NOODLES, MIXED (mixed types including several grain-based dishes), and OTHERS. The proportions of breakfast consumption patterns were 18.4% for skippers, 71.1% for RICE, 2.6% for BREAD, 1.6% for NOODLES, 4.0% for MIXED, and 2.4% for OTHERS. Breakfast skippers had lower daily nutrients intake than breakfast eaters but their health outcomes did not differ from those of eaters. Instead, men with BREAD pattern had higher blood cholesterol and women in NOODLE pattern had higher blood glucose and lower HDL cholesterol. The BREAD pattern breakfast had higher energy contribution from fat and lower nutrient densities and the subjects in BREAD pattern had higher level of household income. Men's BREAD pattern breakfast consisted more animal products than that of women. There was high probability of undernutrition among women in NOODLE pattern and their mean household income was the lowest. From these results, in Korea, breakfast staple types have different food patterns and there was need for developing healthy food patterns appropriate to each staple type. The breakfast consumption pattern had influences on nutrient adequacy of the diet and health outcomes and seemed to represent socio-economic status. These could be used in doing nutrition education in community.

Dietary assessment according to intake of Korean soup and stew in Korean adults: Based on the 2011~2014 Korea National Health and Nutrition Examination Survey (한국 성인의 국물 음식류 섭취에 따른 식생활 평가 : 2011~2014 국민건강영양조사 자료를 이용하여)

  • Kwon, Yong-Suk;Han, Gyusang
    • Journal of Nutrition and Health
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    • v.49 no.5
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    • pp.335-346
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    • 2016
  • Purpose: This study was conducted to conduct dietary assessment of Korean adults according to intake of Korean soup and stew. Methods: To accomplish this study, 20,926 adults aged 19 yr or higher who participated in the dietary intake survey (24 h recall method) were analyzed from the data of the 2011~2014 Korea National Health and Nutrition Examination Survey (KNHANES). The items included in the soup and stew were guk, tang, jjigae, jijimi, and jeongol. Results: Intakes of soup and stew of subjects were divided into quartiles; intake range by quartile was Q1: < 22.96 g, Q2: 22.96~98.75 g, Q3: 98.75~212.23 g, and Q4: $${\geq_-}212.24g$$. In the case of the Q4 group, male, married, employed, higher educated, and high income subjects showed increased intakes of soup and stew. In addition, sodium intake among nutrient intakes increased from 3,849.04 mg in Q1 group to 5,363.57 mg in Q4 group. Intakes of cereals/grains, potatoes/starches, legumes, seeds/nuts, vegetables, mushrooms, fruits, meat, fishes/shell fishes, milks/dairy products, oils/fats, and seasonings among all foods significantly increased from Q1 group to Q4 group. Lastly, in the multivariable regression analysis, male, higher age, married, eating breakfast, consumption of snacks, prepared meals from home/institution, average eating-out frequency per week, energy consumption, and sodium intake related parameters increased intake of Korean soup and stew. Conclusion: Excessive intake of sodium was related to high blood pressure and metabolic syndrome. Thus, there are needs to improve dietary guidelines and nutrition education for balanced intake of soup and stew.

The Related Factors of Atopic Dermatitis Severity in Elementary School Students (일부 초등학생에서 아토피 피부염 증상 관련요인)

  • Choi, Kyung-Mi;Kim, Keon-Yeop;Lee, Moo-Sik;Hong, Jee-Young;Bae, Seok-Hwan;Hwang, Hye-Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.2
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    • pp.759-764
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    • 2011
  • This study was conducted to provide the basic data for the health management of the primary school, by finding and analyzing the factors affecting the degrees of atopic dermatitis symptom's severeness. The subjects of our study were collected 273 pupils mothers, whose children are undergoing through the atopic symptoms. The investigation process took the entire month of the November in 2006. The result of the older the pupils, the severer their symptoms(p<0.05). The longer the period(p<0.01), the more widely spread over the body, and the severer the symptoms(p<0.01). In the dietary habit, the more meat they eat, the severer the symptom(p<0.05). and in relation to the eating the food outside home, the more frequently they eat the fast-food, the severer the symptom. In the multiple logistic regression analysis, using the degrees of atopic dermatitis symptom's severeness as the dependent variables. it is discovered that the longer infection period they have and the more frequently they have the fast-food, the severer the symptom of the atopic dermatitis. The parent's love for the child, the monthly cost for the management of the infection, and the parent's feeling toward the child, can have a greate influence on the physical health, the feelings and the relation with the friends of the infected child, when the child shows the symptoms of scratching his skin. The conclusions of When all the results above are put together, the dietary habit of eating the meals mostly prepared with the meat should be corrected, and the education to form the pupil's right dietary habit, such as, putting the limit on the fast-food, must be made, in order to prevent the symptom of the atopic dermatitis from getting worse. And by the recognizing the atopic dermatitis as the family health problem, the comprehensive family health management, including the mother should be made.