• Journal of Microbiology and Biotechnology
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• 제20권5호
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• pp.950-957
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• 2010

Serratiopeptidase (SRP), a 50 kDa metalloprotease produced from Serratia marcescens species, is a drug with potent anti-inflammatory property. In this study, a powerful statistical design, evolutionary operation (EVOP), was applied to optimize the media composition for SRP production in shake-flask culture of Serratia marcescens NRRL B-23112. Initially, factors such as inoculum size, initial pH, carbon source, and organic nitrogen source were optimized using one factor at a time. The most significant medium components affecting the production of SRP were identified as maltose, soybean meal, and $K_2HPO_4$. The SRP so produced was not found to be dependent on whey protein, but rather was notably induced by most of the organic nitrogen sources used in the study and free from other concomitant protease contaminant, as revealed by protease inhibition study. In addition, experiments were performed using different sets of EVOP design with each factor varied at three levels. The experimental data were analyzed with a standard set of statistical formula. The EVOP-optimized medium, with maltose 4.5%, soybean meal 6.5%, $K_2HPO_4$ 0.8%, and NaCl 0.5% (w/v), gave a SRP production of 7,333 EU/ml, which was 17-fold higher than the unoptimized media. The application of EVOP resulted in significant enhancement of SRP production.

• 한국ITS학회 논문지
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• 제9권4호
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• pp.60-67
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• 2010

꾸준히 증가하는 차량으로 인한 교통문제를 적절한 신호운영 전략을 이용하여 교통흐름을 효율적으로 배분하고 교통군의 흐름을 향상시키기 위한 노력이 시행되고 있다. 최근 국가경쟁력 강화위원회에서는 "기초 법질서 확립을 위한 교통운영체계 선진화 방안"을 발표하여 교통사고, 혼잡비용, 온실가스, 법규위반 등의 문제점을 해결하기 위하여 한국 교통운영 체계를 국제표준에 맞게 수정하는 안을 제시하였다. 본 연구에서는 교통운영체계 개편시 나타나는 효과를 분석하기 위하여 대전시를 사례로 중심으로 좌회전금지, 보호/비보호 혼용 사용시 나타나는 효과를 다양한 시나리오를 통해 정량적으로 분석하였다. 좌회전 금지는 신호현시수를 줄여 신호주기를 줄이는 장점이 있다. 좌회전 금지 지점의 좌회전교통량을 하류부로 이동시켜 U턴을 주어 현시수를 줄인 결과 제어지체는 54.2초에서 22.7초로 크게 향상되었으며, 줄어든 현시로 인하여 농도원네거리방향은 제어지체가 122.2초(F)에서 16.9초(B)로 크게 향상되었다. 또한, 보호/비보호 좌회전을 도입한 결과 좌회전 교통량에 대한 제어지체가 27.0초에서 12.1초로 크게 감소하였다. 향후 좌회전 베이 유무에 따른 비보호 좌회전 허용 기준마련에 대한 연구가 필요하다.

• Nuclear Engineering and Technology
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• 제52권9호
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• pp.2130-2137
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• 2020

The standard method for calculating anti-neutrino emissions from a reactor involves knowing the fractional fission rates for the most important fissioning nuclides in the reactor. To calculate these rates requires detailed reactor physics calculations based upon the reactor design, fuel design, burnup dependent fuel composition, location of specific fuel assemblies in the core and detailed operational data from the reactor. This has only been published for a few reactors during specific time periods, whereas to be of practical use for anti-neutrino reactor monitoring it is necessary to be able to predict these on the publicly available information from any reactor, especially if using these data to subtract the anti-neutrino signal from other reactors to identify an undeclared reactor and monitor its operation. This paper proposes a method to estimate the fission fractions for a specific reactor based upon publicly available information and provides a database based upon a series of spent fuel inventory calculations using the FISPIN10 code and its associated data libraries.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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• pp.244-247
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• 2003

All over the value chain, a logistics information system must satisfy several requirements about gathering and sharing related information. For example, distributors or forwarders need up-to-date information for scheduling and managing their logistics resources. Meanwhile, consignors or consignees want to know the dynamic information about current states or location of their goods. Such information is dependent upon the quality of data sets collected throughout the logistics processes. Thus, gathering accurate data promptly is the essential factor for the success of a logistics information system. However, there are limits in reducing both time-gap and man-power for datn sourcing, since this process is done manually or by using bar codes and scanning devices. Smart-tag can be the alternative to such n time-consuming and inefficient operation, especially for handling piles of goods. The tag includes a micro-chip containing data which is remotely readable by readers with antenna. Logistics system with Smart tag can provide all the information anywhere and anytime, and it will increase the efficiency of logistics and satisfaction of users. In this paper, we propose a conceptual architecture for smart-tag based logistics system and describe its functions.

• 설비공학논문집
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• 제26권10호
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• pp.467-473
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• 2014

Since the operating conditions of HVAC systems are different from those for which they are designed, on-going commissioning is required to optimize the energy consumed and the environment in the building. This study presents a methodology to analyze operational data and its applications. A predicted operation model is to be produced through a statistical data analysis using multiple regressions in SPSS. In this model, the dependent variable is the pre-cooling time, and the independent variables include the power output of the supply air inverter during pre-cooling, the supply air set temperature during pre-cooling, the indoor temperature-indoor set temperature just before pre-cooling, supply heat capacity, and the lowest outdoor air temperature during non-cooling/non-heating hours. The correlation coefficient R2 of the multiple regression model between the pre-cooling hour and the internal/external factors is of 0.612, and this could be used to provide information related to energy conservation and operating guidance.

• 한국음향학회지
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• 제25권7호
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• pp.312-318
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• 2006

기존의 립싱크 시스템은 음소 분할 후, 각각의 음소를 인식하는 2단계의 과정을 거쳤다. 하지만, 정확한 음소 분할의 부재와 음성이 끊긴 분할 된 음소로 이루어진 훈련 데이터들은 시스템의 전체 성능을 크게 떨어뜨렸다. 이런 문제를 해결하기 위해 Head-Body-Tail (HBT) 모델을 이용한 단모음 연속어 인식 기술을 제안한다. 주로 소규모 어휘를 다루는데 적합한 HBT 모델은 Head 와 Tail 부분에 문맥 종속 정보를 포함하여 앞 뒤 문맥에 따른 조음효과를 최대한 반영한다. 또한, 7개의 단모음을 입모양이 비슷한 세 개의 클래스로 분류하여, 클래스에 종속적인 코드북 3개를 가진 반연속HMM (Hidden Markov Model)을 적용하여 시스템을 최적화하고, 변이 부분이 큰 단어의 처음과 끝은 연속HMM의 8 믹스쳐 가우시안 구조를 사용하여 모델링하였다. 제안한 방법은 HBT구조의 연속HW과 대등한 성능을 보이지만, 파라미터 수는 33.92% 감소하였다. 파라미터 감소는 계산 양을 줄여주므로, 시스템이 실시간으로 동작 가능하게 한다.

• 한국항공운항학회지
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• 제25권3호
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• pp.51-60
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• 2017

Estimation of the taxi-out and taxi-in times of aircraft on a airport surface is one of the essential features of Departure Manager (DMAN). Especially for an airport with multiple runways and large ramp areas, estimation of the taxi-out and taxi-in times are mainly dependent on the taxi routes on airport surface. This paper described the method of automatic extraction of the the taxi routes using the ASDE track data and the Dijkstra algorithm based on the node-link model of a airport surface movements. In addition, we analyzed the ground operation status of Incheon International Airport using the extracted taxi routes.

• 한국항공운항학회지
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• 제18권4호
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• pp.100-105
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• 2010

This study is to analyze the performance for ADS-B(Automatic Dependent Surveillance-Broadcast) operations by the Balanced Scorecard(BSC). It is also to collect the opinions of users(pilots, air traffic controllers and ground operators) relating ADS-B and to use the results as data about preparing political measures of aviation safety. For these purpose, BSC model redesigned on 4 different points of view is used for measuring the performance of the ADS-B operation. The proposed perspectives are affairs effectiveness, user orientation, system orientation and the capacity. As the results of this study, it is showed that the continuous development of ADS-B should be required and the users must be involved in the activities, additionally, the relevant authorities should try to be drawn the user-oriented results through the process.

• 한국정밀공학회지
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• 제15권2호
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• pp.107-113
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• 1998

Grinding operation has difficulty in satisfying the qualitative knowledge based on the skilful expert as well as the quantitative data for all user. Design of grinding database based on the frame-based model is more effective method for utilizing the empirical and qualitative knowledge. In this paper. basic strategy to develop the grinding database by taking frame-based model, which is strongly dependent upon experience and intuition, is described. Grinding database based on the frame based model for designing the interaction and inference among the slots is accomplised by the object-oriented paradigm system.

• Korea-Australia Rheology Journal
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• 제16권2호
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• pp.85-90
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• 2004

The present study investigated the deformability of red blood cells (RBC) and its effect on whole blood viscosity using a laser-diffraction slit-rheometer (LDSR). The LDSR has been recently developed with significant advances in laser-diffractometry design, operation and data analysis. While shear stress levels in a slit flow are continuously decreasing, both the deformation of red blood cells and the shear stress were simultaneously measured. Additionally, the viscosity of whole blood was measured using the LDSR. The present study found that the whole blood viscosity is strongly dependent on the RBC deformability. The less deformable the RBCs are, the higher the blood viscosity is.