• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.851-856
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• 2016

Background: Breast cancer is a major health problem among women around the world. Recent developments in screening and treatment have greatly improved the prognosis of patients with breast cancer in developed countries. However, in developing countries breast cancer mortality remains high.Breast cancer awareness is a first and important step in reducing breast cancer mortality. The development of a validated instrument to measure breast cancer awareness is crucial for the understanding and implementation of suitable health education programs to facilitate early deletion and minimize mortality. Objective: The objective of this study was to develop an instrument for the assessment of breast cancer awareness in Thai women. Materials and Methods: This methodological study was conducted in two stages: (1) literature searches and semi-structured interviews were conducted to generate items of the breast cancer awareness scale (B-CAS) which were subsequently examined for content and face validity, and (2) an exploration of the factor structure of the resulting instrument and an examination of its reliability. Data were collected using a self-administered questionnaire in Thai women aged 20-64 in August, 2015. Results: A total of 219 women (response rate 97.4 %) participated in this validation study. The B-CAS contains five domains with 53 items on breast cancer awareness: 1) knowledge of risk factors, 2) knowledge of signs and symptoms, 3) attitude to breast cancer prevention, 4) barriers of breast screening, and 5) health behavior related to breast cancer awareness. Items with a content validity index < 0.80 were excluded, and factor structure for the remaining items reflected the hypothesized five factor model. The scales based on all retained items was shown to have strongly internal consistency reliability (Cronbach's ${\alpha}=0.86$). Conclusions: The B-CAS provides good psychometric properties to assess breast cancer awareness in women. It can be used to examine breast cancer awareness in Thai women and it could lead to the development and evaluation of suitable educational interventions for raising breast cancer awareness. Future research should focus on further validating the B-CAS including an assessment of construct and criterion-based validity.

• 유통과학연구
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• 제13권11호
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• pp.79-92
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• 2015

Purpose - The aim of this study is to develop an empirical model of the effects of traditional market service quality factors on customer value, relationship quality, and behavior. The specific objectives of the study are as follows: 1) to classify study objects into cultural tourism markets and non-cultural tourism markets as well as to verify the differences in service quality among the two markets and, 2) to present practical service marketing methods that fit with the characteristics of the traditional markets by amending the five quality evaluation items of SERVQUAL (a multiple-item scale for measuring service quality)to suit the characteristics of the traditional markets and establish the relationship among customer value, relationship quality, and behavior intention. Research design, data, and methodology - The study methods of empirical investigation are as follows. First, this study selected for a study object the Suwon Paldalmun Gate Market to represent the cultural tourism market, and general traditional markets to represent the non-cultural tourism market. This study also conducted personal interviews in order to increase the response rate and collected a total of 418 responses between March 18, 2014 and April 05, 2014. The total of 418 responses used for this study excluded 14 responses that had either misleading information or missing values. Results - This study verified the perceived differences of service quality based on traditional market specialization through an independent sample t-test. It appeared that the perceived service quality of the cultural tourism market was generally higher than that of the non-cultural tourism market. This study executed a path analysis in order to examine the effects of service quality factors on customer value, relationship quality, and behavior intention. This study also comprehensively analyzed the specialized market and non-specialized market separately. Although there were some differences among the results, the overall results were uniform. It appeared that convenience, reliability, and empathy, among the service quality factors, exerted meaningful effects on customer value. On the other hand, convenience, reliability, responsiveness, and empathy, excluding the tangibles, exerted meaningful effects on the relationship quality. In addition, it appeared that all service quality factors exerted meaningful effects on the customer value, relationship quality, and behavior intention. Therefore, the study verified that all of the hypotheses formulated in the study were generally adopted. Conclusions - The implication of this study may be classified into academic and practical implication as follows. With respect to the academic implication, it seems that this study is among the early studies to verify the differences between the cultural tourism market and the non-cultural tourism market. The practical implication of this study is that the perceived service quality, such as convenience, reliability, responsiveness, and tangibles, excluding empathy, was higher in the cultural tourism market than in the non-cultural tourism market. This means that customer satisfaction is enhanced by governmental aid such as hardware, software, and information and communications technology.

• 한국항해항만학회지
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• 제29권6호
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• pp.537-545
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• 2005

제주도는 전통적으로 전년 내내 온화한 해양기후조건을 가지고 있으며 청정한 자연환경과 극적인 해안경관으로 세계적인 휴양지로 유명하다. 그러나 우리나라 곳곳의 해안지역에서처럼 제주도 역시 해안구조물 건설 및 항만 재개발에 자연환경의 변화에 따른 예측하지 못한 해안침식 문제가 심각하게 대두되고 있다. 이들 지역에서는 섬의 남쪽 해안선에서 침식으로 인한 해안선의 급격한 변화를 보이는 것은 물론 해안선 절벽까지도 무너져 내리는 현상까지 나타나고 있다. 이미 선진국에서는 여러 해안공학자 및 연구자들이 해안침식에 대한 연구를 오랫동안 심도 있게 다루어 왔으나 우리나라에서는 아직 이 방면에 연구 활동이 미약하고 기초연구자료도 미흡하여 대책공법의 수립에 어려움이 존재하며, 무분별한 대책공법의 시행으로 인해 청정해안 환경에 복잡하고 치명적인 영향을 초래할 우려가 있다. 이에 본 연구에서는 외국에서의 여러 사례를 조사하고 해안선 침식방지는 물론 환경친화적이고 친수기능을 겸비한 종합적인 방재 대책공법으로 인공리프, 부유식 방파제 그리고 이중원통 케이슨식 방파제를 찾아내어 제안하고자 하였다. 제안된 방법은 수치모델을 통해 대상해역에 적용하여 그 결과를 비교하여 그 타당성을 평가해 보았다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.2059-2065
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• 2013

This goal of this research was to evaluate the cost-effectiveness of the National Cancer Screening Program (NCSP) for breast cancer in the Republic of Korea from a government expenditure perspective. In 2002-2003 (baseline), a total of 8,724,860 women aged 40 years or over were invited to attend breast cancer screening by the NCSP. Those who attended were identified using the NCSP database, and women were divided into two groups, women who attended screening at baseline (screened group) and those who did not (non-screened group). Breast cancer diagnosis in both groups at baseline, and during 5-year follow-up was identified using the Korean Central Cancer Registry. The effectiveness of the NCSP for breast cancer was estimated by comparing 5-year survival and life years saved (LYS) between the screened and the unscreened groups, measured using mortality data from the Korean National Health Insurance Corporation and the National Health Statistical Office. Direct screening costs, indirect screening costs, and productivity costs were considered in different combinations in the model. When all three of these costs were considered together, the incremental cost to save one life year of a breast cancer patient was 42,305,000 Korean Won (KW) (1 USD=1,088 KW) for the screened group compared to the non-screened group. In sensitivity analyses, reducing the false-positive rate of the screening program by half was the most cost-effective (incremental cost-effectiveness ratio, ICER=30,110,852 KW/LYS) strategy. When the upper age limit for screening was set at 70 years, it became more cost-effective (ICER=39,641,823 KW/LYS) than when no upper age limit was set. The NCSP for breast cancer in Korea seems to be accepted as cost-effective as ICER estimates were around the Gross Domestic Product. However, cost-effectiveness could be further improved by increasing the sensitivity of breast cancer screening and by setting appropriate age limits.

• 컴퓨터교육학회논문지
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• 제23권4호
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• pp.49-59
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• 2020

초중등 교육에서 AI 교육을 어떻게 할지에 대한 논의가 막 시작된 시점에서, 본 연구는 디자인씽킹 기반의 AI 교육 프로그램을 개발, 적용하고 AI 교육 프로그램의 효과를 분석하고자 하였다. AI 교육 프로그램에서 학생들은 자신이 관심있는 AI 문제를 탐색, 정의하고, 필요한 데이터를 수집하여 AI 모델을 구축한 후 스크래치를 활용하여 프로젝트를 개발하였다. AI 교육 프로그램의 효과를 분석하기 위해 SW효과성 측정 지표를 활용하여 학습자의 AI의 가치 인식에 대한 변화와 AI 효능감의 변화를 분석하였다. 또한 AI 프로젝트에 대한 전반적인 인식을 살펴보았다. 연구 결과, AI 효능감은 실제 프로젝트를 수행해보는 경험을 통해 유의미하게 높아졌다. 또한 AI로 문제를 해결하는 것과 관련된 효능감은 프로그래밍 언어 활용 수준이 영향을 미치는 것으로 나타났다. 디자인씽킹 프로세스에 따라 진행된 AI 프로젝트에 대한 학습자의 전반적인 인식은 긍정적이었으며, AI 프로젝트 각 단계(AI 문제 이해 및 문제 탐색, 실습, 문제 정의, 문제해결 아이디어 구현, 평가 및 발표)에 대한 인식 역시 긍정적으로 나타났다. 이러한 긍정적 인식은 프로그래밍 언어활용 수준이 높은 학생들이 더 높게 나타났다. 이러한 결과를 바탕으로 AI 교육을 위한 시사점을 제안하였다.

• 한국ITS학회 논문지
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• 제16권2호
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• pp.92-104
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• 2017

기존의 도로교통의 속도관리 목표는 이동성 및 안전성 개선을 목표로 운영되어 왔으며, 환경적 측면과 에너지 효율 측면에 대한 고려는 미미하였다. 하지만, 최근 들어 기후변화로 인한 경제적 피해규모가 증가하고 있으며, 외부적 여건변화에 따라 환경가치는 상승할 것으로 예상된다. 또한, 교통부문에서의 탄소배출량 저감정책은 개인교통수단에서 대중교통으로 의 전환 및 친환경자동차 개발에만 집중되어있어 상대적으로 도로운영의 개선을 통한 저감 노력이 부족하다는 평가를 받았다. 향후 우리나라의 자동차 보유대수는 증가할 것으로 예상되므로 이에 대한 적응전략 및 대비책이 필요한 시점이다. 이를 위해서는 기존의 이동성 중심의 도로운영 정책에서 환경측면을 고려한 정책으로, 도로운영의 패러다임 전환을 통해 구현할 수 있을 것으로 판단된다. 교통운영 측면에서 온실가스 배출량을 저감하기 위해서는 현재 도로상에서 어느 정도 온실가스가 배출되는지를 실시간으로 모니터링 할 수 있어야 한다. 본 연구에서는 실시간으로 수집되는 교통자료를 이용하여 5분 후의 상태를 예측하고 이를 통해 실시간 온실가스 배출량 모니터링 시스템을 구축할 수 있는 방법론을 제안하였다.

• 한국직업건강간호학회지
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• 제9권1호
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• pp.39-48
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• 2000

Hyperlipemia is the most leading risk factor of cardiovascular disease which is the main cause of death in Korea. However, there is a tendency to neglect the prevention and treatment since it has no specific symptoms. It has been reported that the level of serum-lipid can be lowered by the improvement of eating habits. Therefore, it is highly likely that the development of programs on the improvement of eating habits through behavioral theory is required to the community nursing practice. The theory of planned behavior, which assumes that human behaviors are determined by one's intention to carry out the behavior, can be characterized by the point that behaviors are not only individual factors but also social behaviors relating to subjective norms. It is widely recognized that this theory has a high predictability on health behavior due to it's simplicity clearness, and measurability as well as high quality of being general. Thus, the theory of planned behavior could be useful in developing a model of a health promotion program to the change of behaviors of the risk group of cardiovascular disease. Consequently, based on the theory of planned behavior, the purpose of this study is to develop an intention promotion program of the diet, and then to testify the effects. The sample of this study consisted of 26 industrial workers who had proved hyperlipemia from a medical examination in 1996 (experimental group 13, control group 13). The intention promotion program, which includes education, monitoring, pressure, counselling on the level of individuals, families and organizations, was conducted for 10 weeks The purpose of this program was to promoting intention of the diet through changes of the prerequisite factors of intention such as behavioral belief, outcome evaluation, normative belief and control belief. When it came to data analysis, the ${\chi}^2$-test and Fisher's Exact test were used to compare the general characteristics between the experimental and the control group, an independent t-test for the other variables. ANOVA was used to the test hypothesis, and the Pearson correlation test for variable's correlation. The results of this study can be summarized as follows ; 1) There was a significant increase in the intention(F=18.51, p=.00) of diet in the experimental group. 2) Diets(F=32.51, p=.001) in the experimental group were better carried out than in the control group. 5) There was a moderate correlation between the intention of diet and performance (r=.587. p=.003). From the results, it can be concluded that the intention promotion program is very effective, leading to the change of health promotion behavior. Above all, it is really valuable that the intention promotion program in this study regards health promotion behavior as a social behavior and that intervention was done on the level of family and organization. Consequently, when performing a health promotion program, social approach elevating the intention should go hand in hand in order to make the program effective.

• IMMUNE NETWORK
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• 제12권2호
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• pp.58-65
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• 2012

Background: A cell line with transfected Wilms' tumor protein 1 (WT1) is has been used for the preclinical evaluation of novel treatment strategies of WT1 immunotherapy for leukemia due to the lack of appropriate murine leukemia cell line with endogenous WT1. However, silencing of the transgene occurs. Regarding the effects of hypomethylating agents (HMAs) on reactivation of silenced genes, HMAs are considered to be immune enhancers. Methods: We treated murine WT1- transfected C1498 (mWT1-C1498) with increasing doses of decitabine (DAC) and azacitidine (AZA) to analyze their effects on transgene reactivation. Results: DAC and AZA decreased the number of viable cells in a dose- or time-dependent manner. Quantification of WT1 mRNA level was analyzed by real-time polymerase chain reaction after mWT1-C1498 treated with increasing dose of HMA. DAC treatment for 48 h induced 1.4-, 14.6-, and 15.5-fold increment of WT1 mRNA level, compared to untreated sample, at 0.1, 1, and $10{\mu}M$, respectively. Further increment of WT1 expression in the presence of 1 and $10{\mu}M$ DAC was evident at 72 h. AZA treatment also induced up-regulation of mRNA, but not to the same degree as with DAC treatment. The correlation between the incremental increases in WT1 mRNA by DAC was confirmed by Western blot and concomitant down-regulation of WT1 promoter methylation was revealed. Conclusion: The in vitro data show that HMA can induce reactivation of WT1 transgene and that DAC is more effective, at least in mWT1-C1498 cells, which suggests that the combination of DAC and mWT1-C1498 can be used for the development of the experimental model of HMA-combined WT1 immunotherapy targeting leukemia.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2005년도 춘계학술대회 논문집
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• pp.11-19
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• 2005

제주도는 전통적으로 전년 내내 온화한 해양기후조건을 가지고 있으며 청정한 자연환경과 극적인 해안경관으로 세계적인 휴양지로 유명하다. 그러나 우리나라 곳곳의 해안지역에서처럼 제주도 역시 해안구조물 건설 및 항만 재개발에 자연환경의 변화에 따른 예측하지 못한 해안침식문제가 심각하게 대두되고 있다. 이들 지역에서는 섬의 남쪽 해안선에서 침식으로 인한 해안선의 급격한 변화를 보이는 것은 물론 해안선 절벽까지도 무너져 내리는 현상까지 나타나고 있다. 이미 선진국에서는 여러 해안공학자 및 연구자들이 해안침식에 대한 연구를 오랫동안 심도 있게 다루어 왔으나 우리나라에서는 아직 이 방면에 연구 활동이 미약하고 기초연구자료도 미흡하여 대책공법의 수립에 어려움이 존재하며, 무분별한 대책공법의 시행으로 인해 청정해안 환경에 복잡하고 치명적인 영향을 초래할 우려가 있다. 이에 본 연구에서는 외국에서의 여러 사례를 조사하고 해안선 침식방지는 물론 환경친화적이고 친수기능을 겸비한 종합적인 방재 대책공법으로 인공리프, 부유식 방파제 그리고 이중원통 케이슨식 방파제를 찾아내어 제안하고자 하였다. 제안된 방법은 수치모델을 통해 대상해역에 적용하여 그 결과를 비교하여 그 타당성을 평가해 보았다.

• 한국건축시공학회지
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• 제16권6호
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• pp.505-512
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• 2016

철근콘크리트 건축물의 대형화 및 고층화에 대응하여 고성능 콘크리트가 개발되어 사용되고 있지만 레올로지 특성평가가 적절히 이뤄지지 않아 시공설계를 위한 수치해석에 소성점도 및 항복값의 책정이 적절하지 못한 실정이며 이로 인해 경화된 콘크리트 품질 안정화에 많은 문제점을 나타내고 있다. 본 연구에서는 고로슬래그 미분말 혼입 시멘트 페이스트를 대상으로 물분체비 및 치환율을 실험인자로 응결진행하의 시간경과에 따른 컨시스턴시 곡선을 측정하였다. 빙함모델로 가정한 회귀분석을 통해 소성점도 및 항복값을 산출한 결과 물분체비가 작을수록 초결 전후의 변화가 급격한 것을 알 수 있었다. 치환율을 40%까지 상승시키더라도 자유수변화와 고로슬래그 미분말의 불투수성 산화피막 형성에 의한 코팅효과가 상쇄되어 큰 변화로 관찰되지 않았다.