• Genomics & Informatics
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• v.20 no.2
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• pp.21.1-21.14
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• 2022

The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based on the next-generation sequencing technology. The nasal swabs were collected from patients with influenza-like illness in Thailand during 2017-2018. Then, the influenza A viruses were detected by reverse transcription-quantitative polymerase chain reaction and isolated by MDCK cells. The viral genomes were amplified and sequenced by Illumina MiSeq platform. Whole genome sequences were used for characterization, phylogenetic construction, mutation analysis and nucleotide diversity of the viruses. The result revealed that 90 samples were positive for the viruses including 44 of A/H1N1 and 46 of A/H3N2. Among these, 43 samples were successfully isolated and then the viral genomes of 25 samples were completely amplified. Finally, 17 whole genomes of the viruses (A/H1N1, n=12 and A/H3N2, n=5) were successfully sequenced with an average of 232,578 mapped reads and 1,720 genome coverage per sample. Phylogenetic analysis demonstrated that the A/H1N1 viruses were distinguishable from the recommended vaccine strains. However, the A/H3N2 viruses from this study were closely related to the recommended vaccine strains. The nonsynonymous mutations were found in all genes of both viruses, especially in hemagglutinin (HA) and neuraminidase (NA) genes. The nucleotide diversity analysis revealed negative selection in the PB1, PA, HA, and NA genes of the A/H1N1 viruses. High-throughput data in this study allow for genetic characterization of circulating influenza viruses which would be crucial for preparation against pandemic and epidemic outbreaks in the future.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.2
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• pp.143-150
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• 2021

The recent spread of novel and highly variant pathogenic viruses, including the coronavirus (SARS-CoV-2), has increased the demand for diagnostic testing for rapid confirmation. This has resulted in investigating the functional capability of each space, and preparing facility guidelines to secure the safety of medical technologists. During viral evaluations, there is a requirement of negative pressure facilities along with thread separation, during pre-treatment of samples and before nucleic acid amplification. Space composition therefore needs to be planned by considering unidirectional air flow. This classification of safety management facilities is designated as biosafety level 2, and personal protective equipment is placed accordingly. In case of handling dangerous materials, they need to be carried out of the biosafety cabinet, and sterilizers are required for suitable disposal of infectious agents. A common feature of domestic laboratories is maintenance of the sample pre-treatment space at a negative pressure of -2.5 Pa or less, and arranging separate pre-treatment and reagent preparation spaces during the test process. We believe that the data generated in this study is meaningful, and offers an efficient direction and detailed flow for separation of the inspection process and space functions. Moreover, this study introduces construction of the laboratory by applying the safety management standards.

• Journal of Aerospace System Engineering
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• v.16 no.6
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• pp.54-63
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• 2022

Recently, electric propulsion aircraft with various propeller mounting positions have been under construction. The position of the propeller relative to the wing can significantly affect the aerodynamic performance of the aircraft. Placing the propeller in front of the wing produces a complex swirl flow behind or around the propeller. The up/downwash induced by the swirl flow can alter the wing's local effective angle of attack, causing a change in the aerodynamic load distribution across the wing's spanwise direction. This study investigated the influence of the distance between a propeller and a wing on the aerodynamic loads on the wing. The swirl flow generated by the propeller was modelled using an actuator disk theory, and the wing's aerodynamics were analysed with the VSPAERO tool. Results of the study were compared to wind tunnel test data and established that both axial and spanwise distance between the propeller and the wing positively affect the wing's lift-to-drag ratio. Specifically, it was observed that the lift-to-drag ratio increases when the propeller is positioned higher than the wing.

• Journal of the Korean Geotechnical Society
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• v.38 no.7
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• pp.25-37
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• 2022

In this paper, a small-scale model testing system was developed using a series of small-scale model tests to analyze the mechanism of compaction pile formation and evaluate the quality of controlled grading aggregates proposed as an alternative material to the sand compaction pile (SCP) method and granular compaction pile (GCP). These are the most typical ground improvement methods in field practice, particularly for soft grounds. However, the SCP has faced difficulties due to the supply shortage of natural sand and the corresponding price surge of sand. The GCP is limited in marine soft grounds because of the failure occurring at the pile tip caused by excessive expansion of the deeper bulbs, leading to uneven bulb formation. The uniformity of compacted pile bulbs is critical to ensuring the bearing capacity and quality of the compaction pile. This study aims to evaluate the performance of the new material and controlled grading aggregates using small-scale model tests simulating field compaction process to investigate its potential application in comparison with SCP. The compaction piles are examined in four cases according to different materials used for compaction pile and clay strength. The compaction pile materials, which are made of sand and controlled grading aggregates, used in this study were compared to reveal the mechanism of the bulb creation. The experimental data confirm that the bulb formation quality of the traditional sand and the new material, controlled grading aggregates are comparable. The compaction pile made of controlled grading aggregates presents higher bearing capacity than that of marine sand.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.34 no.4
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• pp.128-134
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• 2022

Nakdong river estuary is being operated with the goal of expanding the period of seawater inflow from this year to 2022 every month and creating a brackish water area within 15 km of the upstream of the river bank. In this study, the deep learning algorithm Long Short-Term Memory (LSTM) was applied to predict the salinity of the Nakdong Bridge (about 5 km upstream of the river bank) for the purpose of rapid decision making for the target brackish water zone and prevention of salt water damage. Input data were constructed to reflect the temporal and spatial characteristics of the Nakdong River estuary, such as the amount of discharge from Changnyeong and Hamanbo, and an optimal model was constructed in consideration of the hydraulic characteristics of the Nakdong River Estuary by changing the degree according to the sequence length. For prediction accuracy, statistical analysis was performed using the coefficient of determination (R-squred) and RMSE (root mean square error). When the sequence length was 12, the R-squred 0.997 and RMSE 0.122 were the highest, and the prior prediction time showed a high degree of R-squred 0.93 or more until the 12-hour interval.

• Journal of the Korean Association of Geographic Information Studies
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• v.25 no.2
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• pp.30-47
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• 2022

This study analyzed the characteristics of cold air flow according to spatial types in urban areas of Changwon-si, Gyeongsangnam-do. The spatial types were classified by cluster analysis considering the land use map, building information, and topographic characteristics produced on the Changwon biotope map. The amount of cold air and wind speed were derived by KLAM_21 modeling. As a result, spatial types were classified into a total of 14 types considering the density and height of buildings, land use types, and topographic characteristics. Cold air flow was found to generate cold air in the valley of the forest area outside urban area, move through roads and open spaces, and accumulate in the low-lying national industrial complex, and then spread cold air throughout the urban areas. There was a lot of cold air flow in the tall building area, and the cold air accumulation was less in the slope and ridge areas. The results of this study were able to understand the characteristics of cold air flow according to building density, land use type, and topography, which will be usefully used as basic data for urban wind road construction to mitigate climate and improve air quality in urban areas.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.6
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• pp.491-496
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• 2021

In line with the modern era in which the safety of underground facilities and the use of underground information are increasingly emphasized, the state is pushing for more precise and accurate underground spatial information to be secured and utilized. Therefore, we need to pay more attention to subsurface geospatial data. In the future, the Ministry of Land, Infrastructure and Transport will actively utilize the 15 types of Integrated Underground Geospatial Information Map(6 types of underground facilities, 6 types of underground structures, 3 types of ground) that the Ministry of Land, Infrastructure and Transport is building as three-dimensional underground spatial information, and contribute greatly to improving national safety and convenience in underground construction. expected to do However, when a site manager requests an Integrated Underground Geospatial Information Map with a mobile device, if the large-capacity integrated underground space map is not quickly transmitted over the wireless section and is not serviced, it causes inconvenience to the site manager and delays work. In this paper, the goal of this paper is to enable field managers to quickly receive a tiled Integrated Underground Geospatial Information Map with minimal information exchange. Therefore, the tiling system is configured according to the dataset for high-speed Mobile Integrated Underground Geospatial Information Map transmission. In addition, a transmission system for the Mobile Integrated Underground Geospatial Information Map is established, and a TCP/IP (Transmission Control Protocol/Internet Protocol)-based spatial information tiling transmission protocol dedicated to the on-site Integrated Underground Geospatial Information Map is developed.

• Journal of Korean Home Economics Education Association
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• v.34 no.1
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• pp.151-165
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• 2022

The aim of this study is to examine the effectiveness of non-face-to-face classes conducted due to the COVID-19 crisis. In order to achieve this goal, a non-face-to-face class with flipped learning was applied in one subject of clothing major held at 'S' University in Cheongju, Korea. In addition, this study tried to analyze the differences between pre- and post-non-face-to-face classes in problem analysis ability, resource/information/technology literacy, convergent thinking ability as core competencies, and overall learning satisfaction. As a result, after participating in the non-face-to-face class in which the flipped learning was applied, the students recognized that their abilities improved in the three problem-solving competency sub-areas, and their overall learning satisfaction also increased. The effectiveness of non-face-to-face classes in the field of clothing and fashion has been mainly measured in fashion design and clothing construction courses. However, based on the results of this study, it can be suggested that non-face-to-face classes in a theory-oriented lecture-type class can be effective methods for improving students' core competencies such as problem-solving skills if teaching-learning methods such as flipped learning are applied. Therefore, the results of this study will be useful data for designing differentiated non-face-to-face class strategies in a theory-oriented lecture-type class to improve the core competencies of college students.

• International Journal of Computer Science & Network Security
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• v.22 no.11
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• pp.141-148
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• 2022

The development of the education system and the labor market today requires new conditions for unification and functioning, the introduction of an innovative culture in the field of Education. The construction of modern management of innovative development of a higher education institution requires consideration of the existing theoretical, methodological and practical planes on which its formation is based. The purpose of the article is to substantiate the modern paradigm of organizing the mechanism of managing the innovative development of higher education institutions. Innovation in education is represented not only by the final product of applying novelty in educational and managerial processes in order to qualitatively improve the subject and objects of management and obtain economic, social, scientific, technical, environmental and other effects, but also by the procedure for their constant updating. The classification of innovations in education is presented. Despite the positive developments in the development of Education, numerous problems remain in this area, which is discussed in the article. The concept of innovative development of higher education institutions is described, which defines the prerequisites, goals, principles, tasks and mechanisms of university development for a long-term period and should be based on the following principles: scientific, flexible, efficient and comprehensive. The role of the motivational component of the mechanism of innovative development of higher education institutions is clarified, which allows at the strategic level to create an innovative culture and motivation of innovative activity of each individual, to make a choice of rational directions for solving problems, at the tactical level - to form motives for innovative activity in the most effective directions, at the operational level - to monitor the formation of a system of motives and incentives, to adjust the directions of motivation. The necessity of the functional component of the mechanism, which consists in determining a set of steps and management decisions aimed at achieving certain goals of innovative development of higher education institutions, is proved. The monitoring component of the mechanism is aimed at developing a special system for collecting, processing, storing and distributing information about the stages of development of higher education institutions, prediction based on the objective data on the dynamics and main trends of its development, and elaboration of recommendations.

• Environmental and Resource Economics Review
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• v.31 no.2
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• pp.233-260
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• 2022

In this paper, we analyzed how oil price fluctuations affect stock price by industry using the non-parametric quantile causality test method. We used weekly data of WTI spot price, KOSPI index, and 22 industrial stock indices from January 1998 to April 2021. The empirical results show that the effect of changes in oil prices on the KOSPI index was not significant, which can be attributed to mixed responses of diverse stock prices in several industries included in the KOSPI index. Looking at the stock price response to oil price by industry, the 9 of 18 industries, including Cloth, Paper, and Medicine show a causality with oil prices, while 9 industries, including Food, Chemical, and Non-metal do not show a causal relationship. Four industries including Medicine and Communication (0.45~0.85), Cloth (0.15~0.45), and Construction (0.5~0.6) show causality with oil prices more than three quantiles consecutively. However, the quantiles in which causality appeared were different for each industry. From the result, we find that the effects of oil price on the stock prices differ significantly by industry, and even in one industry, and the response to oil price changes is different depending on the market situation. This suggests that the government's macroeconomic policies, such as industrial and employment policies, should be performed in consideration of the differences in the effects of oil price fluctuations by industry and market conditions. It also shows that investors have to rebalance their portfolio by industry when oil prices fluctuate.