• 한국의사학회지
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• 제32권1호
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• pp.33-42
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• 2019

Objective : Describe the phenomenon of "clear qi below, turbid qi above" as found in the Somun Eumyangeungsangdaelon (Major Essay on Yinyang Resonances and Appearances 素問 陰陽應象大論) and compare this pattern with water-grain dysentery and flatulence symptom patterns in the Sanghallon (Treatise on Cold Damage). Method : Study the annotation of the Hwangjenaegyeong (Yellow Emperor's Internal Classic 黃帝內經) and compare the results with the Sanghallon's water-grain dysentery and flatulence. Conclusions and Results : The causes of water-grain dysentery and flatulence are associated with the ascending and descending properties of Yin and Yang. Additionally, these symptoms can also be caused by pathogenic heat, turbid pathogenic factors, and interruption of the movement of clear and turbid qi. Aspects of water-grain dysentery resemble several patterns found in the Sanghallon. If caused by a weakness of yang qi, it resembles Sayeoktang (四逆湯) syndrome. Weakness of spleen qi resembles Ijungtang (理中湯) syndrome. Flatulence is similar to fullness in the chest syndrome, which in the Sanghallon is caused by an obstruction of cold qi. If there is excessive cold, water-grain dysentery is similar to the syndrome of Gyeolhyung (結胸). If the qi is not scattered, deficiency syndrome is similar to Gyejigejagyaktang (桂枝去芍藥湯) syndrome and excess syndrome is similar to Mahwangtang (麻黃湯) syndrome. When flatulence is caused by fever in chest, it is similar to Chijasitang (梔子?湯) syndrome. When caused by heat and phlegm build up in chest, it is similar to Sipjotang (十棗湯) syndrome.

• 대한원격탐사학회지
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• 제35권4호
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• pp.545-560
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• 2019

Unlike other critical forest diseases, pine pitch canker in Korea has shown rather mild symptoms of partial loss of crown foliage and leaf discoloration. This study used high-resolution satellite images to detect and monitor canopy decline by pine pitch canker. To enhance the subtle change of canopy reflectance in pitch canker damaged tree crowns, multi-temporal analysis was applied to two KOMPSAT multispectral images obtained in 2011 and 2015. To assure the spectral consistency between the two images, radiometric corrections of atmospheric and shadow effects were applied prior to multi-temporal analysis. The normalized difference vegetation index (NDVI) of each image and the NDVI difference (${\Delta}NDVI=NDVI_{2015}-NDVI_{2011}$) between two images were derived. All negative ΔNDVI values were initially considered any pine stands, including both pitch canker damaged trees and other trees, that showed the decrease of crown foliage from 2011 to 2015. Next, $NDVI_{2015}$ was used to exclude the canopy decline unrelated to the pitch canker damage. Field survey data were used to find the spectral characteristics of the damaged canopy and to evaluate the detection accuracy from further analysis.Although the detection accuracy as assessed by limited number of field survey on 21 sites was 71%, there were also many false alarms that were spectrally very similar to the damaged canopy. The false alarms were mostly found at the mixed stands of pine and young deciduous trees, which might invade these sites after the pine canopy had already opened by any crown damages. Using both ${\Delta}NDVI$ and $NDVI_{2015}$ could be an effective way to narrow down the potential area of the pitch canker damage in Korea.

• Journal of Veterinary Science
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• 제21권5호
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• pp.78.1-78.15
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• 2020

Background: Enteritis is one of the most frequently reported symptoms in piglets infected with porcine circovirus type 2 (PCV2), but the immunopathogenesis has not been reported. Objectives: This study examined the effect of a PCV2 infection on the intestinal mucosal immune function through morphological observations and immune-related molecular detection. Methods: Morphological changes within the ileum of piglets during a PCV2 infection were observed. The expression of the related-molecules was analyzed using a gene chip. The immunocyte subsets were analyzed by flow cytometry. The secretory immunoglobulin A (SIgA) content was analyzed by enzyme-linked immunosorbent assay. Results: The PCV2 infection caused ileal villus damage, intestinal epithelial cells exfoliation, and an increase in lymphocytes in the lamina propria at 21 days post-infection. Differentially expressed genes occurred in the defense response, inflammatory response, and the complement and coagulation cascade reactions. Most of them were downregulated significantly at the induction site and upregulated at the effector site. The genes associated with SIgA production were downregulated significantly at the induction site. In contrast, the expression of the Toll-like receptor-related genes was upregulated significantly at the effector site. The frequencies of dendritic cells, B cells, and CD8⁺T cells were upregulated at the 2 sites. The SIgA content decreased significantly in the ileal mucosa. Conclusions: PCV2 infections can cause damage to the ileum that is associated with changes in immune-related gene expression, immune-related cell subsets, and SIgA production. These findings elucidated the molecular changes in the ileum after a PCV2 infection from the perspective of intestinal mucosal immunity, which provides insights into a further study for PCV2-induced enteritis.

• 한국응용곤충학회지
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• 제61권4호
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• pp.639-640
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• 2022

집나방과(Yponomeutidae)에 속한 작은상제집나방(Saridoscelis sphenias Meyrick)은 2016~2017년 전남 진도와 완도에서 채집된 개체를 동정하여 2020 국내 미기록 종으로 보고되었으며, 마취목(Pieris japonica)과 진달래과에 속한 모새나무(Vaccinium bracteatum Thunb.)와 Leucothoe grayana Maxim. var oblongifolia (Miq.)가 기주식물로 알려져 있었다. 이 종은 2014년 8월 제주특별자치도 블루베리 재배지에서 처음 발견된 후 미정착된 것으로 취급되었으나, 2018년에 이어 2019년에도 제주시와 서귀포시 여러 블루베리 농장에서 발생이 확인되었다. 그 후 2020년부터는 노지 과원에서도 발견되고 있다. 부화유충이 처음 신초 줄기 속으로 침입하여 가해하다가 중간크기로 자란 후 탈출하여 몇 개의 신초를 그물로 철하고 집단적으로 가해하는 등 특이한 피해증상이 나타난다. 향후 피해가 우려되는 해충으로 피해증상과 생활사를 간단히 보고한다.

• Journal of Yeungnam Medical Science
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• 제41권1호
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• pp.45-47
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• 2024

Peripheral nerves may be affected or injured for several reasons. Peripheral nerve damage can result from trauma, surgery, anatomical abnormalities, entrapment, systemic diseases, or iatrogenic injuries. Trauma and iatrogenic injuries are the most common causes. The ulnar, median, and radial nerves are the most injured nerves in the upper extremities, while the sciatic and peroneal nerves are the most injured nerves in the lower extremities. The clinical symptoms of peripheral nerve damage include pain, weakness, numbness/ tingling, and paresthesia. Therefore, early diagnosis and appropriate treatment of peripheral nerve injuries are crucial. If a peripheral nerve injury is left untreated, it can lead to severe complications and significant morbidity. The sciatic nerve is one of the most affected nerves. This nerve is generally injured by trauma and iatrogenic causes. Children are more susceptible to trauma than adults. Therefore, sciatic nerve injuries are observed in pediatric patients. When the sciatic nerve is damaged, pain, weakness, sensory loss, and gait disturbances can occur. Therefore, the diagnosis and treatment of sciatic nerve injuries are important to avoid unexpected consequences. Ultrasound can play an important role in the diagnosis of peripheral nerve injury and the follow-up of patients. The aim of this case report is twofold. First, we aimed to emphasize the critical role of ultrasonographic evaluation in the diagnosis of peripheral nerve injuries and pathologies. Second, we aimed to present this case, which has distinguishing features, such as the existence of periostitis ossificans progressiva with sciatic neurotmesis due to a traumatic glass injury.

• 환경생물
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• 제39권3호
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• pp.319-328
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• 2021

토마토반점위조바이러스(TSWV)는 고추, 토마토 등 경제적으로 중요한 작물에 심각한 피해를 주는 바이러스들 중 한 종이다. TSWV의 넓은 기주범위, 매개충인 총채벌레 방제의 어려움 및 TSWV의 효과적인 치료제가 없기 때문에, 저항성 품종을 사용하는 것이 TSWV를 예방하는 가장 효과적인 수단이 될 수 있다. 본 연구에서는 토마토에서 분리된 TSWV 분리주(SW-TO2)의 유전학적·생물학적 특성을 구명하고, 최근에 국내에서 분리된 구기자, 머위, 당귀 TSWV 분리주와 비교하였다. 순수분리된 SW-TO2는 28종의 지표식물 중 토마토를 포함한 17종에서 원형반점, 모자이크 증상 등 전신감염 증상을 보였다. SW-TO2의 유전자 계통분석 결과 국내에서 분리된 고추, 구기자 TSWV 분리주와 98~99%의 상동성을 보이며 같은 그룹에 속하였다. TSWV 저항성 평가를 위한 생물검정법을 확립하고, 시판되고 있는 고추와 토마토 품종을 대상으로 4종의 TSWV 분리주에 대한 저항성 평가를 검정하였다. TSWV 저항성 평가는 첫째, 접종엽에 괴사반점 증상이 나타나거나 병징이 없는 경우, 둘째, 상엽에 병징이 없는 경우, 셋째, 상엽을 RT-PCR 진단한 결과 음성이 나왔을 경우 등 3가지 조건이다 충족될 때 저항성으로 평가하였다.

• Clinical and Experimental Pediatrics
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• 제56권12호
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• pp.540-544
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• 2013

Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however, Down syndrome with multiple neurologic conditions is rare. Here, we have reported a case of Down syndrome in a 10-year-old girl who presented with asymptomatic moyamoya syndrome, atlantoaxial subluxation with spinal cord compression, and basal ganglia calcification. To the best of our knowledge, this is the first report of Down syndrome, in a child, which was accompanied by these 3 neurologic complications simultaneously. As seen in this case, patients with Down syndrome may have neurologic conditions without any obvious neurologic symptoms; hence, patients with Down syndrome should be carefully examined for the presence of neurologic conditions.

• Journal of Preventive Medicine and Public Health
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• 제15권1호
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• pp.205-211
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• 1982

This survey was conducted to find out demage done to the farmers by Agrochemicals in a rural area of Korea from January to October, 1980. Choon Sung Gun, Kang Won Province was the survey area and the 412 males were surveyed among all those that have sprayed agrochemicals during 10 Months in 1980. Obtained results and findings from this survey are summarized as follows; 1. The total spray days of 413 males were 3,114 days and avarage spray days per person were 7.54 days. Also avarage spray hours per person were 4.7 hours. 2. The incidence rate per 100 persons of self-recognized skin manifestation was 12.6 persons and incidence rate per spray day was 2.7 percent. The incidence rate per 100 persons of self-recognized intoxication was 23.0 persons and incidence rate per spray day was 3.6 percent. 3. In cases where mask was not used, when it was syrayed in hot weather, when stronger solution was used, the results were higher percentage in self-recognized intoxication (P<0.01). 4. The symptoms of self-recognized intoxication were headache (55.8%), dizziness (46.9%), nausea (17.7%), fatigue (17.0%), and vomiting (17.0%), 5. Number of intoxication per 100 used standardized unit by agrochemicals was parathion (93.8 spells), sumithion (91.8 spells) and folithion (66.7 spells). 6. Treatment was done by health facility utilization (27 cases), visits to drug store (13 cases) and visits to health center (7 cases).

• 한국식품영양학회지
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• 제23권4호
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• pp.435-439
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• 2010

The aim of this study was to evaluate the anti-inlfammatory effects of Glycyrrhiza glabra Linne extract on ulcerative colitis induced by 3% dextran sulfate sodium in mice. The experimental animals were divided into six groups: control(normal), DSS-induced colitis(control), 1 mg/kg, 10 mg/kg, and 100 mg/kg of Glycyrrhiza glabra Linne extract, and 150 mg/kg 5-aminosalicylic acid(5-ASA)(positive control). We evaluated the pathological disease activity index(DAI), change in weight, colon mucosa damage and myeloperoxidase(MPO) in colon mucosa. Treatment with 10 mg/kg and 100 mg/kg of Glycyrrhiza glabra Linne extract led to significant loss of body weight, the decrease of MPO activity and clinical symptoms such as DAI and histological change. In particular, 100 mg/kg Glycyrrhiza glabra Linne extract led to markedly greater improvement than 150 mg/kg 5-ASA treatment. These results suggest that Glycyrrhiza glabra mediated anti-inflammatory action on colorectal sites may be a useful therapeutic approach to ulcerative colitis.

• 한국어병학회지
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• 제6권2호
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• pp.197-204
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• 1993

Flounder culture has been developed mainly in the western parts of japan, and, to date, following six bacterial diseases have been reported. Bacterial white enteritis occurs in 16 to 30-day-old flounder larvae and often causes mass mortality in seed production. Bacterium named Vibrio sp. INFL invades and multiplies in the mucosae of posterier part of intestine, and causes desquamative enteritis. Gliding bacterial disease occurs mostly in juvenile stage and in spring to summer. Diseased signs are partial discoloration and erosion of skin and fins. Histologically, epidermis are removed, and the causative bacterium, Flexibacter maritimus, multiplies on the surface of demis and invades into the muscular tissue. Vibriosis caused by Vibrio anguillarum and related organisum is one of the well-known diseases among marine fish. Outbreaks of the disease in flounder culture are relatively few, but mass mortalities in fingerlings due to the disease were reported. An outbreak of nocardiosis in the autumn of 1984 has been reported, but since then the disease scarcely occurred. The disease is characterized by formation of abscesses under the skin and white nodes in the gill, heart, spleen and kidney. Streptococcicosis occurs frequently in recent years. Beta-hemolytic streptococcus is the causative bacterium, which possesses the same biochemical and serological characteristics as $\beta$-streptococci isolated from some marine and freshwater fish, and is seemed to related to Streptococcus iniae. Edwardsiellosis is the disease that causes most damage in flounder culture in Japan. Characteristic symptoms are swelling of abdomen and intestinal protrusion from the anus due to accumulation of ascites. Edwardsiella tarda, a well-known pathogen of freshwater fish, is the causative bacterium of the disease.