• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.1
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• pp.168-174
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• 1998

This study was conducted to determine whether Mildronate, an analogue of carnitine, influences blood alcohol concentration and hang-over syndrome in rabbits and healthy college male students. In the animal study, ten rabbits were randomly divided into two groups. One hundred mg per 1kg body weight of Mildronate was injected twice into five rabbits before injecting 50% ethanol; the rest of rabbits were injected with saline. The human study was performed with two sections. Each section of the study was conducted by a two-phase cross-over design with a four day wash-out period. All volunteers took Mildronate in one phase, and took a placebo in the next phase. The difference between the two sections was related to the time of taking the Mildronate pill and the amount of alcohol consumed. Blood alcohol concentrations were not significantly different between in those taking Mildronate and in those taking the placebo in both the human and the animal study. However, the concentration of serum aspartate aminotransferase(AST, GOT), the indicator of liver cell damage, was lowered in those taking Mildronate, compared to those taking the placebo. Also, headache and heartburn among hang-over syndrome patients were less severe with Mildronate. In conclusion, taking Mildronate prior to drinking alcohol can somewhat reduce liver cell damage and hang-over syndrome without stimulating alcohol metabolism.

• Smart Structures and Systems
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• v.21 no.2
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• pp.171-185
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• 2018

Maintenance of deteriorated bridge structures has always been one of the challenging issues in developing countries as it is directly related to daily life of people including trade and economy. An effective maintenance strategy is highly dependent on timely inspections on the bridge health condition. This study is intended to investigate an approach for detecting bridge damage for the long-term health monitoring by use of copula theory. Long-term measured data for the seven-span plate-Gerber bridge is investigated. Autoregressive time series models constructed for the observed accelerations taken from the bridge are utilized for the computation of damage indicator for the bridge. The copula model is used to analyze the statistical changes associated with the modal parameters. The changes in the modal parameters with the time are identified by the copula statistical properties. Applicability of the proposed method is also discussed based on a comparison study among other approaches.

• Journal of Korean Biological Nursing Science
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• v.15 no.2
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• pp.74-81
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• 2013

Purpose: This study was conducted to explore the health effects of exposure to oil-contaminated water in G village near the area of Daecheon beach on which air force had test fired. Methods: Eighty residents consented and were divided into three groups; 33 residents(drinking well water and still living there), 23 residents(drinking well water but do not live there any more), and 24 residents(did not drink well water but live there now: control group). Data were collected from August to September, 2010 from the survey questionnaires, general health examination, specific functional test, and biological marker tests. Results: Current residents showed higher levels of body mass index, blood pressure, and fasting blood glucose that are related to adult diseases. 64 participants received specific test for cancer. Only one person had esophageal cancer. Perchloroethylene was not found in the Urine Samples. Current residents showed a higher level of 8-hydroxydeoxyguanosine, an indicator of oxidative damage, and there was a statistically significant difference after correcting the confounding variables. Conclusion: We need education programs for managing the risk factors that are related to adult diseases in people who are now living in this village. We also need to expand further studies for investigating oxidative damage indicators.

• Current Photovoltaic Research
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• v.3 no.4
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• pp.112-115
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• 2015

In this study, the surface of ITO films was modified using $N_2-O_2$ molecular plasma, and the effects of oxygen concentration in the plasma on the ITO surface properties were investigated. Upon plasma treatment of ITO films, the surface roughness of ITO films seldom changed up to the oxygen concentration in the range of 0% to 40%, while the roughness of the films slightly changed at or above the oxygen concentration of 60%. The contact angle of water droplet on ITO films dramatically changed with varying oxygen concentration in the plasma, and the minimum value was found to be at the oxygen concentration of 20%. The plasma resistance at this condition exhibited a maximum value, and the change of resistance showed an inverse relationship compared to that of contact angle. From these results, it was conjectured that the chemical reactions in the sheath of the molecular plasma dominated more than the physical actions due to energetic ion bombardment, and also the plasma resistance could be used as an indirect indicator to qualitatively diagnosis the state of plasma during the plasma treatment.

• Journal of Chest Surgery
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• v.22 no.3
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• pp.402-415
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• 1989

Extracorporeal circulation leads to functional disorder and structural damage of organs, especially hematologic and pulmonary system, mainly by sequestration of neutrophils and deposition of macrophages at lung. Then, proteases are secreted, which insult vascular basement membrane of pulmonary capillary and alveolar septa of the lung. Among these, the most important protease at lung is elastase, because major component of lung is elastin. For prevention of lung injury, inactivators or antidotes to elastase should be necessary and Alpha 1-Proteinase Inhibitor is the elastase inactivator. Clinical experimental study was carried out to investigate the immediate postoperative change of serum Alpha 1-PI level following cardiopulmonary bypass for 20 heart cases [congenital 16 cases, acquired 4 cases] and 10 control [subtotal gastrectomy] cases. Also preliminary study was performed for 31 cases of open heart patients. The results were as follows: l. Immediate postoperative serum levels of Alpha 1-PI was significantly decreased at open heart surgery group [P< 0.005], but not decreased at control group. 2. There were no significant difference in change of serum Alpha 1-PI level between and membrane and bubble oxygenator group.Z 3. There were no significant difference in changes of serum Alpha 1-PI level between CHD and AHD. Alpha 1-PI is consumed at lung during cardiopulmonary bypass and increase after operation compensatedly and protect multiple organic damage especially lung. Therefore, Alpha 1-PI can be indicator for evaluation of prevention and treatment of pump-lung syndrome.

• Wind and Structures
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• v.29 no.3
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• pp.177-194
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• 2019

While establishing adequate load paths in the light-frame wood structures is critical to maintain the overall structural integrity and avoid significant damage under extreme wind events, the understanding of the load paths is limited by the high redundant nature of this building type. The objective of the current study is to evaluate the system effects and investigate the load paths in the wood structures especially the older buildings for a better performance assessment of the existing building stock under high winds, which will provide guidance for building constructions in the future. This is done by developing building models with configurations that are suspicious to induce failure per post damage reconnaissance. The effect of each configuration to the structural integrity is evaluated by the first failure wind speed, amajor indicator beyond the linear to the nonlinear range. A 3D finite-element (FE) building model is adopted as a control case that is modeled using a validated methodology in a highly-detailed fashion where the nonlinearity of connections is explicitly simulated. This model is then altered systematically to analyze the effects of configuration variations in the model such as the gable end sheathing continuity and the gable end truss stiffness, etc. The resolution of the wind loads from scaled wind tunnel tests is also discussed by comparing the effects to wind loads derived from large-scale wind tests.

• Journal of Ocean Engineering and Technology
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• v.37 no.3
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• pp.111-121
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• 2023

This paper intends to introduce the applicability of HydroQus to a problem of a tanker collision against a semi-submersible type floating offshore wind turbine (FOWT). HydroQus is a plug-in based on potential flow theory that generates interactive hydroforces in a commercial Finite element analysis (FEA) code Abaqus/Explicit. Frequency response analyses were conducted for a 10MW capacity FOWT to obtain hydrostatic and hydrodynamic constants. The tanker was modeled with rigid elements, while elastic-plastic elements were used for the FOWT. Mooring chains were modeled to implement station keeping ability of the FOWT. Two types of fracture models were considered: constant failure strain model and combined failure strain model HC-LN model composed of Hosford-Coulomb (HC) model & localized necking (LN) model. The damage extents were evaluated by hydroforces and failure strain models. The largest equivalent plastic strain observed in the cases where both restoring force and radiation force were considered. Stress triaxiality and damage indicator analysis showed that the application of HC-LN model was suitable. It could be stated that applications of suitable failure strain model and hydrodynamics into the collision simulations were of importance.

• 대한핵의학회:학술대회논문집
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• 2001.05a
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• pp.4-10
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• 2001

The radionuclide therapy is a protocol for tumor control by administering radionuclides as the cytotoxic agents. Radionuclides concentrated at the site of cancerous lesion are expected to kill the cancerous cells with minimal injury to the normal tissue. The efficacy of every radionuclide treatment can be evaluated by examining the toxicity to the lesion differentiated from that to the normal tissue. Radiation dosimetry is the procedure of quantitating the energy absorbed by target volumes of interest. Dosimetric information plays an indicator of the expected radiation damage and thus the therapeutic efficacy. This paper summarizes the dosimetric aspects in radionuclide therapy in terms of radionuclides of use, radiation dosimetry methodology and considerations for each treatment in practical use.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.911-916
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• 2005

Noise map is a presentation of existing data or predicted noise situation in terms of noise indicator. However, it has shortcoming for assessing the number of people exposed, or the number of dwellings affected to any relevant limit values of noise level in certain areas. In this study, so called over-ride value noise mapping is proposed to make up for the shortcoming by using over-ride function of object-oriented programming and it is to show the guard of the area where it is satisfied the standard of option, or it is not satisfactory. Over-ride value noisemap data is combined with topography layer, population and house statistics, and GIS space statistical analysis. The over-ride value noise mapping can also he applied to make the road traffic noisemap, the railroad noisemap, the aircraft noisemap, and the industrial site noisemap This can express noise damage information more exactly.

• Journal of the Korean Institute of Landscape Architecture
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• v.28 no.2
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• pp.97-107
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• 2000

This study aims to develop the model of evaluation on greenspace to increase the sustain ability of the planning and management for site-scale development projects. The results of this study can be summarized as follows: (1) The comprehensive principles of sustainable development projects were established, which include coexistence of man and nature, reflection of ecological principles, minimization of environmental pollution and damage, recycling and reuse of materials. (2) According to established principles, the evaluation criteria were classified into seven categories as follows: retention of ample greenspace, formation of greenspace as a habitat, species diversity of vegetation, consideration of indigenous plants, construction of green network, conservation of greenspace, and reuse of plant materials. (3) As a result of the analysis of questionnaire of experts, evaluation model was worked out with which we can evaluate environmental friendliness greenspace. And, the final evaluation indicators for greenspace are the rate of greeneries volume, securing habitat, indigenous plants, reuse of plant materials, and species diversity of vegetation, and the indicator of greenspace conservation.