• Journal of Ginseng Research
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• 제28권1호
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• pp.18-26
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• 2004

The effect of Panax ginseng administration in muscle inflammatory process induced after eccentric exercise, that causes myofibrillar disruption, was studied. Changes in lipid peroxidation, inflammation, glycogen levels in muscle and release of myocellular proteins to blood were measured. The analyses were performed immediately after eccentric exercise and over week since this period are necessary for the muscle damage-repair cycle. The ginseng extract (100 mg kg$^{-1}$ ) was orally administered to rats for three months, before the eccentric exercise performance. The results showed the protective role of ginseng against skeletal muscle damage. This effect could be associated with their membrane stabilising capacity since creatine kinase (CK) activity was significantly decreased 96 h post-exercise from 523$\pm$70 to 381$\pm$53 and 120 h post-exercise from 443$\pm$85 to 327$\pm$75 in treated animals. $\beta$-glucuronidase activity, as indicator of inflammation, showed a significant reduction of about 15-25% in soleus, vastus and triceps in these post-exercise times. The lipid peroxidation, measured by malondyaldehyde levels, was significantly decreased in the 24 h post-exercise period in soleus and vastus intermedius muscles and on the recovery period. Finally ginseng administration reduced significantly the decrease of the glycogen levels immediately after exercise and when the regenerative process took place (72-168 h post exercise). Collectively, the results have showed that ginseng did not inhibit the vital inflammatory response process associated with the muscle damage-repair cycle but presumably ameliorate the injury.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2002년도 학술대회지
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• pp.159-175
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• 2002

The effect of Panax ginseng administration in muscle inflammatory process induced after eccentric exercise, that causes myofibrillar disruption, was studied. Changes in lipid peroxidation, inflammation, glycogen levels in muscle and release of myocellular proteins to blood were measured. The analyses were performed immediately after eccentric exercise and over week since this period are necessary for the muscle damage-repair cycle. The ginseng extract $(100\;mg\;kg^{-1})$ was orally administered to rats for three months, before the eccentric exercise performance. The results showed the protective role of ginseng against skeletal muscle damage. This effect could be associated with their membrane stabilising capacity since creatine kinase (CK) activity was significantly decreased 96 h post-exercise from $523{\pm}70\;to\;381{\pm}53$ and 120 h post-exercise from $443{\pm}85\;to\;327{\pm}75$ in treated animals. ${\beta}-glucuronidase$ activity, as indicator of inflammation, showed a significant reduction of about $15-25\%$ in soleus, vastus and triceps in these post-exercise times. The lipid peroxidation, measured by malondyaldehyde levels, was significantly decreased in the 24 h postexercise period in soleus and vastus intermedius muscles and on the recovery period. Finally ginseng administration reduced significantly the decrease of the glycogen levels immediately after exercise and when the regenerative process took place (72-168 h post exercise). Collectively, the results have showed that ginseng did not inhibit the vital inflammatory response process associated with the muscle damage-repair cycle but presumably ameliorate the injury.

• 자원환경지질
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• 제52권6호
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• pp.573-586
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• 2019

우리나라 전역을 대상으로 공간 분석 기반 지진 위험 지도를 작성하고 지진 취약 지역을 평가하였다. 지진 피해에 영향을 미치는 지질학적 특성을 고려하여 지표를 선정하였으며, 지진 활동 위험과 관련된 확률론적 지진 위험도 및 단층 특성, 지진 피해 위험과 연관된 기반암 심도 정보가 이용되었다. 각 지표는 정규 크리깅, 선 밀도 및 가변적 지역 평균 기반 단순 크리깅과 같은 GIS 및 지구 통계학 기법을 활용하여 공간 정보로 구축되었다. 구축된 세 가지 공간 정보는 연구 목적, 자료의 해상도 및 정확도에 따라 가중치를 할당하여 통합되었다. 지진 활동 위험 지표인 확률론적 지진 위험도와 단층 선 밀도의 경우 데이터의 불확실성이 비교적 크기 때문에 경향성 만을 반영하고자 먼저 가중 합한 후, 지진 피해 위험 지표인 기반암 심도 분포와 통합되었다. 이를 통해 세 가지 공간 자료의 분석에 기반한 지진 위험 지도가 작성되었으며, 우리나라 남동부와 북서부 지역이 지진 위험도가 높은 것으로 평가되었다. 본 연구 결과는 지진 재해를 최소화하기 위한 지진 대응 시스템을 구축하는데 기초 자료로 활용될 수 있을 것으로 기대된다.

• 한국지진공학회논문집
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• 제5권3호
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• pp.65-71
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• 2001

원자력발전소(원전)는 운전기준지진(OBE) 초과지진 발생시 안전성 검사와 시험을 위하여 운전을 정지하여야 하는데, 계측된 지진기록의 누적절대속도(CAV)계산 값이 0.16g-sec를 초과하고 OBE 응답스펙트럼을 초과하면 OBE를 초과한 것으로 고려하게 된다. 이 CAV 기준은 발전소의 지진 특성과 구조물의 특성에 따라 다르므로, 발전소에 적합한 CAV 기준을 설정하여야 한다. 국내 원전에 적합한 CAV 기준 값을 설정하기 위하여, 각 방향에서의 지진하중에 일관되게 반응하도록 고안한 원통모양의 아크릴 봉을 조립한 지진손상표시기(SDI)를 제작, 진동대 시험을 통하여 지진의 세기를 평가하고 국내 원전 내진설계에 적용된 CAV값을 계산한 결과0.3~0.5g-sec으로 나타나 OBE 초과기준으로 CAV기준 값(0.16g-sec)의 적용은 충분히 보수적인 값으로 나타났다. 본 연구를 통하여 개발된 SDI는 발전소 운전원이 OBE 초과 여부를 판단하는데 도움을 줄 수 있을 뿐만 아니라 운전 정지 후 원전의 지진 피해도를 정량적으로 판단하여 조치를 취하는 도구로 활용될 수 있을 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제16권11호
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• pp.1577-1582
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• 2003

This study was conducted to determine the effects of prophylactic supplementation of vitamin E and Se on oxidative damage and antioxidant status. Fifteen healthy male buffalo (Bubalus bubalis) calves between the age of 6 to12 months were divided into three groups of five animals each: Group I-control, group II-endotoxic shock group infused with lyophilized E coli endotoxin @ 5 ${\mu}g$/kg body wt, and group III-supplemented with vitamin E @ 250 mg and Se @ 7.5 mg, one month prior to induction of endotoxic shock. All the animals in group II and group III exhibited signs of endotoxic shock. When the endotoxic shock was induced, there was significant (p<0.05) increase in the circulating levels of malonyl dialdehyde MDA (an indicator of lipid peroxidation). In the supplemented group III the magnitude of formation of MDA was also less as compared to group II at every stage of study. There was significant (p<0.05) decrease in circulating levels of SOD, GSH-Px, Catalase and G-6-PD activity from the normal (0 h) value with passage of time. As a result of endotoxic shock, these values reached a lowest value, and then showed a tendency towards the 0 h value. Prophylactic supplementation with vitamin E and Se was successful in reducing the quantum of oxidative damage due to formation of free radicals because of endotoxic shock.

• 대한기계학회논문집A
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• 제28권10호
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• pp.1467-1474
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• 2004

In this study, a new damage identification method for beam-like structures with a fatigue crack is proposed. which does not require comparative measurement on an intact structure but require several measurements at different level of excitation forces on the cracked structure. The idea comes from the fact that dynamic behavior of a structure with a fatigue crack changes with the level of the excitation force. The 2$^{nd}$ spatial derivatives of frequency response functions along the longitudinal direction of a beam are used as the sensitive indicator of crack existence. Then, weighting function is employed in the averaging process in frequency domain to account for the modal participation of the differences between the dynamic behavior of a beam with a fatigue crack at the low excitation and one at the high excitation. Subsequently, a damage index is defined such that the location and level of the crack may be identified. It is shown from the analysis of vibration measurements in this study that comparison of frequency response characteristics of a beam with a single fatigue crack at different level of excitation forces enables an effective detection of the crack.

• 한국화재소방학회논문지
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• 제29권4호
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• pp.89-94
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• 2015

본 연구는 국민 소방안전의식 수준에 적합한 눈높이 소방안전정책을 실행하는데 도움을 주기 위하여, 소방안전의식 지표를 개발하고 국민 소방안전의식을 조사하기 위한 목적으로 실행되었다. 이를 위하여 소방안전의식에 대해 정의를 하고 이를 효율적으로 측정할 수 있는 지표를 예방, 경보, 대피, 소화, 피해확대방지의 5가지 분야로 세분화하여 소방안전의식 측정지표를 도출하였다. 지표개발은 파라슈라만(Parasuraman) 방식을 이용하였으며 국내 외 선행연구 자료와 전문가 회의를 거쳐 개발하였다. 개발된 지표를 활용하여 한국갤럽에 의뢰하여 국민 소방안전의식을 조사하였고 이를 분석한 결과 대피의식이 가장 낮았고 다음이 소화, 경보, 예방, 피해확대 방지 순으로 나타났다.

• 한국압력기기공학회 논문집
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• 제12권2호
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• pp.50-57
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• 2016

The study presents structural integrity assessment of ductility degradation of a baffle former assembly by performing finite element analysis considering real loading conditions and stress triaxiality. Variations of fracture strain curves of type 304 austenitic stainless steel with stress triaxiality are derived based on the previous study results. Temperature distributions during normal operation such as heat-up, steady state, and cool-down are calculated via finite element temperature analysis considering gamma heating and heat convection with reactor coolant. Variations of stress and strain state during long operation period are also calculated by performing sequentially coupled temperature-stress analysis. Fracture strain is derived by using the fracture curve and the stress triaxility. Finally, variations of ductility degradation damage indicator with the fracture strain and the equivalent inelastic strain are investigated. It is found that maximum value of the ductility degradation damage index continuously increases and becomes 0.4877 at 40 EFPYs. Also, the maximum value occurs at top and middle inner parts of the baffle former assembly before and after 20 EFPYs, respectively.

• Smart Structures and Systems
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• 제11권1호
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• pp.19-34
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• 2013

The objective of this paper is to develop on-line system parameter estimation and damage detection technique from the response measurements through using the Recursive Covariance-Driven Stochastic Subspace identification (RSSI-COV) approach. To reduce the effect of noise on the results of identification, discussion on the pre-processing of data using recursive singular spectrum analysis (rSSA) is presented to remove the noise contaminant measurements so as to enhance the stability of data analysis. Through the application of rSSA-SSI-COV to the vibration measurement of bridge during scouring experiment, the ability of the proposed algorithm was proved to be robust to the noise perturbations and offers a very good online tracking capability. The accuracy and robustness offered by rSSA-SSI-COV provides a key to obtain the evidence of imminent bridge settlement and a very stable modal frequency tracking which makes it possible for early warning. The peak values of the identified $1^{st}$ mode shape slope ratio has shown to be a good indicator for damage location, meanwhile, the drastic movements of the peak of $2^{nd}$ mode slope ratio could be used as another feature to indicate imminent pier settlement.

• 한국암반공학회:학술대회논문집
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• 한국암반공학회 2006년도 춘계학술발표회 논문집
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• pp.79-93
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• 2006

It is well known that acoustic emission (AE) is indicator of rock fracturing or damage as rock is brought to failure under the uniaxial compressive loads. In this paper, an experimental study on the source location of acoustic emission on the cylindrical specimens of granite under uniaxial compression test was made. The AE source location was made by measuring the six channel AE data. Comparing to this experiment, the numerical method is applied to model the initiation and propagation of fracture by AE using a numerical code, RFPA (Realistic Failure Process Analysis). This code incorporates the mesoscopic heterogeneity in Young's modulus and rock strength characteristic of rock masses. In the numerical models, values of Young's modulus and rock strength are realized according to a Weibull distribution in which the distribution parameters represent the level of heterogeneity of the medium. The results of the simulations show that RFPA can be used not only to produce acoustic emission similar to those measurements in our experiments, but also to predict fracturing patterns under uniaxial loading condition.