• Child Health Nursing Research
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• 제16권4호
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• pp.268-276
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• 2010

Purpose: The purpose of this study was to provide basic data to improve coping abilities of elementary school students in emergency situations. Method: The data were collected from 1633 3-6th grade elementary school students using a self-report questionnaire. Results: 1) The mean score for the coping ability of the students was low at .38(${\pm}.36$). 2) The mean scores for the 8 categories were, [Care for common symptoms], .54(${\pm}.48$), [Call for help & check], .47(${\pm}.43$), [Care for injury by heat cold & foreign body], .39(${\pm}.45$), [Care for tissue damage], .36(${\pm}.44$), [Offering help], .36(${\pm}.42$), [Rescue & escape], .31(${\pm}.51$), [Evacuation], .28(${\pm}.49$), and [Appropriate response for the situation], .27(${\pm}.43$). The mean scores for 2 areas were, 'Acting tips', .35(${\pm}.36$) and 'First aid', .42(${\pm}.40$). There were significant differences in coping ability according to students' gender (t=4.964, p<.001), and family type (t=-2.484, p=.013). 4) Among the categories, there were significant correlations between all 8 categories and significant correlation between 'Acting tips' and 'First aid' (r=.808, p<.001), 'Acting tips' and 'Coping ability' (r=.956, p<.001), and 'First aid' and 'Coping ability' (r=.946, p<.001). Conclusion: The findings indicate a need for programs to improve the coping ability of elementary school students in emergency situations.

• 한국주거학회논문집
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• 제23권5호
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• pp.1-8
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• 2012

Recently, there have been frequent occurrence of the damage to lives and properties due to the torrential rain caused by climate change. In consideration of the current situations in which the underlying data related to flooding are lacking, this study conducted to build up the basic data on the flooded areas and suggested methods to secure the evacuation routes that can be accessible to evacuation facilities in the residential buildings. Methods of the study are as follows. First, We calculated the flood risk grades of residential buildings based on elevations, considering the flooding characteristics of the flooded areas in Buk-gu, Daegu. Second, We constructed baseline data on the evacuation routes through site investigation and reviewed of drawing using Arc GIS to identify vulnerability to access to the evacuation facilities, targeting the residential buildings. Third, We carried out the proximity analysis through a near analysis of analysis functions in ARC GIS. Forth, We deduced 115 residential buildings in which access to evacuation facilities is considered to be difficult based on the analysis results. Finally, We proposed extension of a blind alley as a means for achieving connectivity to evacuation facilities. And to evaluate the alternatives presented, we reconstructed route data. As a result, about 53% improvement was identified through the proximity analysis.

• Child Health Nursing Research
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• 제12권1호
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• pp.44-56
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• 2006

Purpose: The purpose of this study was to investigate the health education needs of mothers who are nurturing children with disabilities. Method: A descriptive study was done and the participants were 108 mothers of children with disabilities such being mentally challenged, developmentally delayed or having a disability involving brain damage. The questionnaire was a health education need assessment with 11 categories(58 items) developed by Han et al. The data were analyzed using SPSS program. Results: The mean score for health education needs of the mothers of children with disabilities was 3.83 (SD=0.58) out of a maximum 5. The health education need for acquisition of knowledge and information had the highest score (4.40±0.54) followed by health education needs for cognitive development and learning (4.31±0.64), interpersonal relationships (4.04±0.65) and behavior and emotion (4.04±0.79). There were significant differences between the children's sex (t=2.08, p=.04), birth order (t=2.17, p=.03), grade of disability (F=3.32, p=.02) and sex education suitable to the child's in age. Conclusion: The health education needs of mothers of children who are disabled were very high and varied. Therefore, it was important to develop comprehensive education programs which include this content and provide opportunities for mothers of children with disabilities to receive this education.

• 한국방재안전학회논문집
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• 제6권1호
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• pp.35-45
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• 2013

최근 기후변화에 따른 집중호우 발생으로 급경사지 붕괴가 빈번히 발생하고 있으며, 이로 인한 재산 및 인명피해 발생으로 급경사지에 대한 관심이 급증하고 있다. 따라서 소방방재청에서는 급경사지 붕괴위험지구를 지정하여 예방사업을 추진하고 있지만, 과학적이고 합리적인 급경사지 예방정책을 마련하기 위한 지반재해위험지도를 제작 중에 있다. 본 연구를 통해서 서울시 부산시의 최근 4년간(2009~2012) 급경사지 피해사례를 조사 정리하여 지반재해위험지도의 적용성을 평가하였으며, 서울시 부산시 내 테스트베드 지역을 선정하여 관계 전문가들과 함께 현장 적용성 평가를 수행하였다. 연구 결과 지반재해위험지도의 위험등급은 실제 현장평가를 통해 확인한 위험등급과 같거나 높게 분석되는 것으로 확인되었다. 따라서 지반재해위험지도를 활용하여 재해위험 예비지구를 선정하고 전문가의 현장검증 및 평가를 통해 위험지구를 최종 선정하는 등 재해위험지구대상을 예비평가 할 수 있는 자료로서 활용도가 높을 것으로 판단된다.

• Geomechanics and Engineering
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• 제20권6호
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• pp.485-495
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• 2020

Based on the movement characteristics of overlying strata with gangue backfilling, the compression test of gangue is designed. The deformation characterristics of gangue is obtained based on the different Talbot index. The deformation has a logarithmic growth trend, including sharp deformation stage, linear deformation stage, rheological stage, and the resistance to deformation changes in different stages. The more advantageous Talbot gradation index is obtained to control the surface subsidence. On the basis of similarity simulation test with gangue backfilling, the characteristics of roof failure and the evolution of the supporting force are analyzed. In the early stage of gangue backfilling, beam structure damage directly occurs at the roof, and the layer is separated from the overlying rock. As the working face advances, the crack arch of the basic roof is generated, and the separation layer is closed. Due to the supporting effect of filling gangue, the stress concentration in gangue backfilling stope is relatively mild. Based on the equivalent mining height model of gangue backfilling stope, the relationship between full ratio and mining height is obtained. It is necessary to ensure that the gradation of filling gangue meets the Talbot distribution of n=0.5, and the full ratio meets the protection grade requirements of surface buildings.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3623-3626
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• 2016

Breast cancer is very common and the leading cause of cancer deaths among women globally. Hereditary cases account for 5-10% of the total burden and CHEK2, which plays crucial role in response to DNA damage to promote cell cycle arrest and repair or induce apoptosis, is considered as a moderate penetrance breast cancer risk gene. Our objective in the current study was to analyze mutations in related to breast cancer. A total of 271 individuals including breast cancer patients and normal subjects were enrolled and all 14 exons of CHEK2 were amplified and sequenced. The majority of the patients (>95%) were affected with invasive ductal carcinoma (IDC), 52.1% were diagnosed with grade III tumors and 56.2% and 27.5% with advanced stages III and IV. Two novel nonsense variants i.e. c.58C>T (P.Q20X) and c.256G>T (p.E85X) at exon 1 and 2 in two breast cancer patients were identified, both novel and not reported elsewhere.

• Journal of Korean Neurosurgical Society
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• 제46권2호
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• pp.93-98
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• 2009

Objective: Although prophylactic antiepileptic drug (AED) use in patients with aneurysmal subarachnoid hemorrhage (SAH) is a common practice, lack of uniform definitions and guidelines for seizures and AEDs rendered this prescription more habitual instead of evidence-based manner. We herein evaluated the incidence and predictive factors of seizure and complications about AED use. Methods: From July 1999 to June 2007, data of a total of 547 patients with aneurysmal SAH who underwent operative treatments were reviewed. For these, the incidence and risk factors of seizures and epilepsy were assessed, in addition to complications of AEDs. Results: Eighty-three patients (15.2%) had at least one seizure following SAH. Forty-three patients (79%) had onset seizures, 34 (6.2%) had perioperative seizures, and 17 (3.1%) had late epilepsy. Younger age (< 40 years), poor clinical grade, thick hemorrhage, acute hydrocephalus, and rebleeding were related to the occurrence of onset seizures. Cortical infarction and thick hemorrhage were independent risk factors for the occurrence of late epilepsy. Onset seizures were not predictive of late epilepsy. Moreover, adverse drug effects were identified in 128 patients (23.4%) with AEDs. Conclusion: Perioperative seizures are not significant predictors for late epilepsy. Instead, initial amount of SAH and surgery-induced cortical damage should be seriously considered as risk factors for late epilepsy. Because AEDs can not prevent early postoperative seizures (< 1 week) and potentially cause unexpected side effects, long-term use should be readjusted in high-risk patients.

• 동의생리병리학회지
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• 제24권2호
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• pp.302-309
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• 2010

Oxidative stress has been implicated in cutaneous damage in various inflammatory skin diseases, including atopic dermatitis (AD). Atoberry is the herb medicine extract which is composed with Spirodelae Herba, Xanthii Fructus, Houttuyniae Herba, Taraxaci Herba, Retinervus Luffae Fructus, Platycodi Radix, and Scutellariae Radix. In this study, we investigated the antioxidant and anti-inflammatory effects of Atoberry in AD-like skin lesion NC/Nga mice. Murine AD-like skin lesions were made by painting Dermatophagoides farinse (Df) extract. Atoberry significantly increased electron donating ability (DPPH), nitrite scavenging (NO) and superoxide dismutase (SOD) activities in dose dependant. Topically applied Atoberry significantly reduced clinical severity score, ear thickness and histological grade in AD-like skin lesion NC/Nga mice. In addition, the serum levels of IgE, NO and prostaglandin E2 were significantly reduced by Atoberry. Futhermore, skin tissue levels of SOD, catalase and glutathione peroxidase (GPx) were significantly reduced by Atoberry. These results demonstrate that topical application of Atoberry may be improve the AD-like skin lesion by antioxidant and anti-inflammatory effects.

• Molecular & Cellular Toxicology
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• 제4권4호
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• pp.360-365
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• 2008

In the last several years, studies on the association of oxidative stress damage with exposure in the work place have been conducted. Xenobiotics create an imbalance of the homeostasis between oxidant molecules and antioxidant defense. By monitoring oxidative stress biomarkers, information was obtained on damages induced by oxidative stress and the toxicity of xenobiotics. In the present study, a Job Exposure Matrix (JEM) was constructed using the data from the Working Environment Measurement (WEM) of painters in the shipyard industry from the past 3 years to assess the exposure status. Additionally, by measuring the concentration of urinary malondialdehyde (MDA), the effect of lipid peroxidation was examined. The subjects consisted of 68 workers who were exposed to mixed organic solvents in the painting process and 25 non-exposure controls. The exposure indices of the exposure groups were significantly different (sprayer: 0.83, touchup: 0.54, assistant: 0.13, P<0.05). The urinary MDA concentration of the exposure group was 48.60${\pm}$ 39.23 ${\mu}mol$/mol creatinine, which was significantly higher than 18.03${\pm}$16.33 ${\mu}mol$/mol creatinine of the control group (P<0.05). From the multiple regression analysis of urinary MDA, the regression coefficient for exposure grade was statistically significant. In future studies, evaluation of the antioxidant levels of subjects should be performed simultaneously with quantitative exposure measurements.

• 한국구조물진단유지관리공학회 논문집
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• 제20권5호
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• pp.50-57
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• 2016

교량의 안전은 점검에 의해 보장된다. 그리고 교량의 유지관리는 점검결과를 토대로 시작된다. 따라서 점검결과는 '교량의 안전'과 '효율적인 유지관리'를 위한 가장 중요한 정보이다. 따라서 본 논문에서는 교량의 점검신뢰도를 평가하고 이를 제고 할 수 있는 방안을 제시하고자 한다. 이를 위해 본 논문에서는 교량의 점검신뢰도를 평가 할 수 있는 세 가지 점검신뢰도를 제시하였다: 명목점검신뢰도, 실질점검신뢰도, DS명목점검신뢰도. 교량의 점검신뢰도 분석 방법은 정밀안전진단결과를 참값으로 간주하고 당해년도 정밀(정기)점검과 차년도 정밀안전 진단결과를 비교하였다. 인적오류를 고려한 DS명목신뢰도를 기준으로 현재 고속도로교량의 점검신뢰도 85%로 양호한 편으로 평가 된다. 이는 현재 고속도로 교량의 평균공용연수가 13년으로 대부분의 교량이 'A'와 'B'등급에 집중적으로 분포되어 상태변화가 크지 않기 때문인 것으로 판단된다. 점검신뢰도를 제고하기 위해서는 점검자의 역량을 강화하고 전문점검인력 육성이 필요하며 점검결과에 대해 QC(Quality Control, 품질관리)를 실시하여 점검결과의 신뢰도 향상이 필요하다.