• Journal of Nutrition and Health
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• 제39권8호
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• pp.773-785
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• 2006

Vitamin E in the body system plays an important role in preventing chronic diseases by decreasing the oxidative stress by free-radicals. However, there are not enough researches on analyzing the primary factors affecting vitamin E levels in the blood in Korean adults. Therefore, the purpose of this research was to examine blood tocopherol levels and the primary factors affecting the status. A complete lifestyle survey was performed on 314 Korean adult men and surveyed their smoking, drinking and exercising habits. The average plasma level of ${\alpha}-\;and\;{\gamma}-tocopherol$ showed similar mutual relations with plasma total cholesterol (TC), triglyceride (TG), or low density lipoprotein cholesterol (LDL-C) levels (p<0.001). Plasma ${\alpha}-tocopherol$ level of the subjects did not show any difference as smoking, drinking and exercising habits changed. However, ${\gamma}-tocopherol$ per TG showed much lower figure in smokers than non smokers (p < 0.05). Amongst diet factors, plasma ${\alpha}-tocopherol$ level showed negative correlations with Vitamin E intake, while ${\gamma}-tocopherol$ level showed positive correlations with Vitamin E intake. Erythrocyte superoxide dismutase (SOD) activity and plasma tocopherol showed negative correlations, and catalase activity and plasma ${\alpha}-tocopherol$ showed positive correlationship. The level of cell DNA damage of Iymphocyte and plasma ${\alpha}-\;or\;{\gamma}-tocopherol$ showed negative correlations. As a result of this research, the factors that affect Korean adult men's plasma ${\alpha}-tocopherol$ level are plasma TG, LDL-C and cell DNA damage in Iymphocyte, while the factors that affect ${\gamma}-tocopherol$ level are plasma TG, LDL-C and vitamin E intake based on multiple regression analysis. These findings implies that the level of different types of tocopherol depends on slightly different factors. A further research is needed on the factors involved in the differentiation of the types of tocopherol.

• 대한토목학회논문집
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• 제7권1호
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• pp.43-54
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• 1987

본 논문에서는 압축반복하중을 받는 콘크리트의 피로누가손상 특성이 연구되었다. 압축을 받는 무근콘크리트의 원주형 공시체에 대한 기초실험을 통하여, 콘크리트의 누가손상에는 여러 인자들 중에서 반복적으로 작용되는 응력의 수준과 재하순서가 가장 크게 영향을 마친다는 것을 발견하였다. 이를 기초로 2단계 응력수준 조건하에서의 피로실험을 실시하여, 콘크리트의 누가손상특성은 Miner의 선형이론을 따르기 보다는 오히려 비선형의 상관관계를 가지며, 응력의 재하방법에 따라 누가손상의 특성과 콘크리트의 정적강도가 변화됨을 구명하였다. 또한 본 연구를 통하여 2 단계 응력수준하에서 콘크리트의 피로특성과 콘크리트구조의 잔존수명을 예측하는데 사용될 수 있는 실험공식이 도출되었다.

• Journal of Chest Surgery
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• 제16권1호
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• pp.97-101
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• 1983

The steadily increasing number of operations performed on the heart has given rise to occasional complications involving the nervous system, and this has been interested to cardiac surgeons and neurologists. This survey has been carried out on all Gases submitted to open heart surgery at Seoul National University Hospital during 1982 to determine which operative features were associated with the occurrence of neurological damage. 514 subjects were studied and neurological damage was noted in twenty-five patients [4.9%]. Eight of these 25 patients died in the postoperative period, but neurological damage contributed to the fatal outcome in six cases. Remaining seventeen patients were discharged without problems except one Cortical blindness and one hemiplegic patients who were survived without other problems . A number of features were found to be related to the development of neurological damage, which were age, duration of perfusion, nature of operation, cardiac rhythm and presence of the thrombi or calcification and hypothermic arrest. But many unknown etiological factors are remained out of our sight. A significant increase in the incidence of neurological damage was shown in older age group [13.3% in over 40 year of age], and also the duration of the bypass was associated with subsequent neurological injury especially more than 120 minutes [11.6%]. The presence of atrial fibrillation with intracardiac thrombi or calcification was also a contributing factor to developing neurological complication [16.7%]. These factors were regarded to influence the postoperative neurological complications and more effective method for prevention of these neurologic complication should be studied.

• Molecules and Cells
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• 제43권2호
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• pp.99-106
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• 2020

Cells are constantly exposed to endogenous and exogenous stresses that can result in DNA damage. In response, they have evolved complex pathways to maintain genomic integrity. RUNX family transcription factors (RUNX1, RUNX2, and RUNX3 in mammals) are master regulators of development and differentiation, and are frequently dysregulated in cancer. A growing body of research also implicates RUNX proteins as regulators of the DNA damage response, often acting in conjunction with the p53 and Fanconi anemia pathways. In this review, we discuss the functional role and mechanisms involved in RUNX factor mediated response to DNA damage and other cellular stresses. We highlight the impact of these new findings on our understanding of cancer predisposition associated with RUNX factor dysregulation and their implications for designing novel approaches to prevent cancer formation in affected individuals.

• 수산경영론집
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• 제54권2호
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• pp.045-058
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• 2023

This study aims to analyze the cost of climate change damages to laver and sea mustard aquaculture, which are considered to be highly vulnerable to climate change in Korea. For this purpose, the correlation between aquaculture production and climate factors such as water temperature, salinity, air temperature, and precipitation was estimated using a panel regression model. The SSP scenario was applied to predict the changes in production and damage costs due to changes in future climate factors. As a result of the analysis, laver production is predicted to decrease by 18.0-27.2% in 2050 and 20.6-61.6% in 2100, and damage costs are predicted to increase from 29.7-50.8 billion KRW in 2050 to 35.7-116.1 billion KRW in 2100. Sea mustard production is projected to decrease by 24.5-37.2% in 2050 and 24.0-34.5% in 2100, with similar damage costs of 41.1-61.8 billion KRW and 41.1-58.6 billion KRW, respectively. These damage costs are expected to occur in the short term as damage caused by fishery disasters such as high temperatures, and in the long term as a decrease in production due to changes in aquaculture sites. Therefore, measures such as strengthening the forecasting system to prevent high-temperature damage, developing high-temperature-resistant varieties, and relocating fishing grounds in response to changes in aquaculture sites will be necessary.

• 대한토목학회논문집
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• 제30권4B호
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• pp.361-366
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• 2010

시군구간의 잠재적 홍수피해 위험성을 계량적으로 비교할 수 있다면 지역단위의 치수계획을 수립하거나 국가의 치수예산 집행 우선순위를 결정하는데 큰 도움이 된다. 본 연구에서는 지역별 홍수피해의 잠재적 위험성을 손쉽게 파악할 수 있는 홍수피해지표(Flood Damage Index : FDI)를 제안하였다. 홍수피해지표는 홍수피해에 영향을 미치는 직 간접적 요인들을 자연적 요인, 사회적 요인, 정책적 요인, 시설적 요인이라는 네 가지로 구분한 후, 이들을 대표하는 11개 주요 인자들을 선정하고, 인자별 가중치와 무차원 인자값들을 곱하여 합산한 지표이다. 이 지표를 이용하여 전국 229개 시군구의 잠재적 홍수피해 위험성을 비교하였고, 지역별 홍수발생요인도 분석하였다. 연구결과는 보다 합리적인 치수대책수립에 활용될 수 있다.

• Corrosion Science and Technology
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• 제11권5호
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• pp.205-212
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• 2012

With recent advances in engineering and technology, a damage on industrial machineries performing high-speed and high-power requirements has become a problem. There is an increasing possibility of cavitation damage, especially in pumps, propellers and high-speed vessels in a flowing liquid accordingly. There are several factors affecting cavitation damage on materials, including viscosity, pressure, temperature, amplitude applied. In this study, effects of cavity pressure in seawater on the damage for 5083-O aluminium alloy were evaluated by modulating amplitude. Trend of the damage with respect to time and amplitude was analyzed comparatively, and surface degradation of specimens was investigated by using Scanning Electron Microscope(SEM) and 3D microscope. The result reveals that the amount of the damage increased consistently with the increase in time and amplitude while the plastic deformation zone where no appreciable damage occurred was in less than 30 minutes.

• Smart Structures and Systems
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• 제6권9호
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• pp.991-1005
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• 2010

The key to detecting damage to civil engineering structures is to find an effective damage indicator. The damage indicator should promptly reveal the location of the damage and accurately identify the state of the structure. We propose to use the distance measures of low-order AR models as a novel damage indicator. The AR model has been applied to parameterize dynamical responses, typically the acceleration response. The premise of this approach is that the distance between the models, fitting the dynamical responses from damaged and undamaged structures, may be correlated with the information about the damage, including its location and severity. Distance measures have been widely used in speech recognition. However, they have rarely been applied to civil engineering structures. This research attempts to improve on the distance measures that have been studied so far. The effect of varying the data length, number of parameters, and other factors was carefully studied.

• 한국환경농학회지
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• 제33권1호
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• pp.52-56
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• 2014

BACKGROUND: It is known that impacts of climate change on damage occurrence by insect pests and diseases are increasing. The negative effects of climate change on production will threaten our food security. It is needed that on the basis of analysis of the impacts, proper strategies in response to climate change are developed. METHODS AND RESULTS: The objective of this paper is to estimate impacts of climate change on rice damage occurrence by insect pests and diseases, using the panal model which analyzes both cross-section data and time series data. The result of an analysis on impacts of climate change on rice damage occurrence by pest insect and disease showed that the damage occurrence by Rice leaf roller and Rice water weevil increased if temperature increased, and damage occurrence by Stripe, Sheath blight, and Leaf Blast increased if precipitation(or amount of sunshine) increased(or decreased). CONCLUSION: Adaptation strategies, supplying weather forecasting information by region, developing systematical strategies for prevention of damage occurrence by pest insect and disease, analyzing the factors of damage occurrence by unexpected pest insect and disease, enforcing international cooperation for prevention of damage occurrence are needed to minimize the impacts of damage occurrence on rice production.

• 한국측량학회:학술대회논문집
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• 한국측량학회 2007년도 춘계학술발표회 논문집
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• pp.371-374
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• 2007

For development of landslide risk assessment techniques using GIS(Geographic Information System), this study classifies the category of socioeconomic factors. The landslide quantitative risk assessment performs first prediction of flow trajectory and runout distance of debris flow over natural terrain. Based on those results, it can be analyzed the factors of socioeconomic which are directly related to the magnitude of risk due to landslide hazards. Those risk assessment results can deliver factual damage situation prediction to policy making for the landslide damage mitigation. Therefore, this study is based on feature classification of the digital map ver. 2.0 provided by the National Geographic Information Institute. The category of factors can be used as useful data in preventing landslide.