• Proceedings of the Korean Vacuum Society Conference
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• 2010.08a
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• pp.188-188
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• 2010

동일한 에너지와 일정한 dose량을 유지하고 dose rate만을 변화시켜가며 이온을 Si(100) 표면에 주입하였다. 이러한 조건하에서 이온의 dose rate가 커지게 되면 시료 내에서 relaxation되는 시간이 짧아져서 damage의 양이 증가하게 되고 depth profile의 꼬리부분이 표면 쪽으로 올라오게 된다. 이와 같은 damage profile의 변화가 sheet resistance에 영향을 준다는 실험결과가 있다. 본 연구에서는 Crystal-TRIM computer simulation을 통해서 depth profile과 damage profile의 결과를 얻고, dose rate가 커질수록 시료표면 근방에 잔류 damage의 양이 높게 나타나는 것을 확인할 수 있다. 또한, 잔류 damage의 표면근방에서의 분포가 annealing 이후 sheet resistance를 변화시키는데 이에 대한 mechanism을 규명하고자 한다.

• The Korea Journal of Herbology
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• v.29 no.5
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• pp.39-43
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• 2014

Objectives : The purpose of this sutdy was finding out the origin and daily dose of Allii Fistulosi Bulbus in Treatise on Cold Damage Diseases. Methods : In order to estimate the origin and daily dose of Allii Fistulosi Bulbus, I researched the Treatise on Cold Damage Diseases, Synopsis of Prescription of the Golden Chamber, Classified Emergency Materia Medica, Compendium of Materia Medica, and Huangdi's Internal Classic. Results : According to some important herbal textbooks, Allii Fistulosi Bulbus had no seed, was reproduced by rhizome, and its leaves were soft. Chongbaek in Treatise on Cold Damage Diseases did not include word 'raw'. The unit of the dose of it was the number of article. So Allii Fistulosi Bulbus in Treatise on Cold Damage Diseases was not Daepa but Jokpa, and was dried, and was round shaped bulb bigger than bean. The daily dose was 4, 9, 14 articles in Treatise on Cold Damage Diseases and Synopsis of Prescription of the Golden Chamber. These were estimated equal to 1, 2, 3 Ryang. 1 Ryang equals to 6.5 g in Treatise on Cold Damage Diseases, so the daily dose of Allii Fistulosi Bulbus was estimated 6.5 g, 13.0 g, and 19.5 g. I weighed the middle-sized Allii Fistulosi Bulbuses, the result was remarkably consistent with the estimated numerical value. Conclusions : In Treatise on Cold Damage Diseases, Allii Fistulosi Bulbus was dried bulb of Jokpa of Allium fistulosum Linn$\acute{e}$ and the daily dose was 4 or 9 articles, respectively equaled to 1 Ryang, 2 Ryang and 6.5 g, 13 g.

• The Korea Journal of Herbology
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• v.35 no.1
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• pp.19-25
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• 2020

Objects : The daily dose of Pinelliae Tuber in ≪Treatise on Cold Damage Diseases≫ is half seung in volume, two and half ryang in weight, and fifteen in total number. But the daily dose should be a whole number. So I found out the background of this setting and correct solution. Methods : I searched Classics of Traditional Medicine, found out the background of the daily dose setting, solution. Results : The daily dose of Pinelliae tuber in ≪Hangdi's Internal Classic Miraculous Pivot≫, ≪Bohenggyuljangbuyongyakbeobyo≫ is half seung. ≪Treatise on Cold Dameage Diseases≫ followed the same daily dose of that because it referred to these books. In ≪Synopsis of Prescription of the Golden Chamber≫, the daily dose of that is half seung, one or two seung. The half seung of the Pinelliae Tuber is thirty three mL, but the diameter is 1~1.5 cm that accurate measurement by volume is difficult. The daily dose by weight is correct considering the unity of marking of the daily dose, accuracy of measurement, the fact that Pinelliae Tuber is currently distributed by cutting. So, two ryang is correct which is thirteen gram. Conclusions : Considering the traditionality, the convenience of measurement, the daily dose of Pinelliae Tuber in the ≪Treatise on Cold Damage Diseases≫ is half seung, but considering the unity, accuracy, current state of distribution, it is correct that the daily dose of it is two ryang. It corresponds to thirteen gram.

• The Korea Journal of Herbology
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• v.30 no.4
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• pp.51-55
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• 2015

Objectives : The purpose of this study was finding out the daily dose of Aconiti Lateralis Radix Preparata and Aconiti Lateralis Radix in Treatise on Cold Damage Diseases.Methods : In order to estimate the daily dose of Aconiti Lateralis Radix Preparata and Aconiti Lateralis Radix, I researched Treatise on Cold Damage Diseases, Synopsis of Prescription of the Golden Chamber, Korean Pharmacoepia 10 and Science of Contemporary Chinese Medicine Product.Results : Daily doses of Aconiti Lateralis Radix Preparata are 1, 2, or 3 pieces and those amount are respectively 1, 2, or 3 Ryang. Common dose of Aconiti Lateralis Radix Preparata is 1 piece, Maximum Dose of it is 3 Pieces and that corresponds with dose of dried herb in Treatise on Cold Damage Diseases. Consider from Sovereign, Minister, Assistant and Courier, the dose of it in Buja-tang and Whyunmu-tang is 3 Ryang. 1 Ryang corresponds with 6.5 g. Aconiti Lateralis Radix is dried without baking so its weight is equal to Aconiti Lateralis Radix Preparata. Daily doses of Aconiti Lateralis Radix are 1 piece or 1 big piece and those amount are respectively 3 or 6 Ryang. Common dose of it is 1 piece.Conclusions : From this study, in Treatise on Cold Damage Diseases, Daily Doses of Aconiti Lateralis Radix Preparata are 1, 2, or 3 pieces(19.5 g, 39 g or 52 g), and that of Aconiti Lateralis Radix are 1 piece or 1 big piece(19.5 g, 39 g). Common Dose of two Herbal Medicine is 19.5 g.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.242-242
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• 2010

Si(100) 표면에 이온을 일정한 에너지로 dose량을 동일하게 유지하고, dose rate만을 변화시켜가며 주입한 후에 depth profile과 damage, 그리고 sheet resistance를 조사하였다. 일정한 에너지로 이온을 주입하여도 dose rate의 변화에 따라서 depth profile에 변화를 보이는 것을 확인할 수 있었고 sheet resistance역시 dose rate변화에 비례하여 변화하는 것을 확인할 수 있었다. 본 연구는 Crystal-TRIM program으로 computer simulation 하여 damage profile의 결과를 통해 dose rate가 클수록 시료 표면 근처에 잔류 damage의 양이 높게 나타나는 것을 알 수 있었고 그 잔류 damage의 표면근방 분포가 sheet resistance에 직접적인 영향을 미친다는 것을 확인할 수 있었다.

• The Korea Journal of Herbology
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• v.32 no.1
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• pp.41-45
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• 2017

Objectives : The purpose of this study was to assume the origin and daily dose of Allii Chinensis Bulbus in Treatise on Cold Damage Diseases and Prescriptions of the Gold Chamber. Methods : I assumed the origin with Book of Materica Medica such as Illustration and Classic of Materia Medica(本草圖經), Illustration and Consideration of Plant's Name and Reality(植物名實圖考), The Korean Herbal Pharmacopoeia Forth Edition, Annotation of Hangeul Treatise of Cold Damages Diseases, and daily dose based on general principle applied on dose of Treatise on Cold Damage Diseases. Results : In Treatise on Cold Damage Diseases and Prescriptions of the Gold Chamber, the original species of Allii Chinensis Bulbus was Allium chinense G. Don. It was to be measured with weight. It was too big to write on size due to it's 10~30mm length and 3~12mm in diameter. And due to irregular size, it can't be written on number, too. Daily dose of Allii Chinensis Bulbus in Whaeyeok-san(回逆散), Gwalluhaebaekbanha-tang(栝樓薤白半夏湯) was 3 Ryang(兩), which was the most common case in Treatise on Cold Damage Diseases. And that in Gwalluhaebaekgyeji-tang(栝樓薤白桂枝湯), Gwalluhaebaekbaekju-tang(栝樓薤白白酒湯) is 8 Ryang(兩), which was the largest dose as dried herb in Treatise on Cold Damage Diseases Conclusions : The original species of Allii Chinensis Bulbus was Allium chinense G. Don. The daily dose of Allii Chinensis Bulbus was 3 Ryang(兩)(19.5g) in Whaeyeok-san and Gwalluhaebaekbanha-tang, and was 8 Ryang(兩)(52g) in Gwalluhaebaekgyeji-tang and Gwalluhaebaekbaekju-tang.

• The Korea Journal of Herbology
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• v.28 no.1
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• pp.51-58
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• 2013

Objectives : As Daily Dose of Zizyphi Fructus was designated by the numbers in Treatise on Cold Damage Disease, estimation of Daily Dose was all different among researchers. The purpose of this study was to estimate exact Daily Dose of Zizyphi Fructus. Methods : We fixed the errors in various copy of Treatise on Cold Damage Disease and considered the meaning of the Bee Zizyphi Fructus(肥大棗) and general rules of Daily Dose in Treatise on Cold Damage Disease. So we reduced Daily Dose of Zizyphi Fructus, and compared this with the standard of Zizyphy Fructus in Pharmacopoeia of several Nation and Korean Forest Service. Results : Daily Dose of Zizyphi Fructus was generally 12 pieces; less was for prescriptions which scaled down the amount of ingredients prescribed in the originals; 15, 25, and 30 pieces were used when more was required. The medicinal part was the pulp of fructus, and the dosage of 12 pieces was respectively equivalent to 3 Ryang(兩), and 19.5 g. As defined in the Korean Pharmacopoeia Ninth Edition and standards of forest products by Korea Forest Service, Zizyphi Fructus was medium-sized, and weighs about 1.625 g if properly dehydrated. Conclusions : In short, the proper Daily Dose of Zizyphi Fructus in Treatise on Cold damage Disease was 12 pieces of Zizyphi Fructus and 19.5 g of its pulp, weighing three Ryang(兩). The pulp was estimated to be 1.625 g; it was medium-sized according to the present standard.

• The Korean Journal of Emergency Medical Services
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• v.10 no.1
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• pp.51-60
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• 2006

Background: The toxicity of paraquat has been known to be caused by oxygen free radicals which leads to the lipid peroxidation and multiple organ failure. High dose vitamin C has been known to be a effective antioxidant activities against the paraquat intoxication. This study was designed to evaluate the effect of regular injection of high dose vitamin C on liver damage in paraquat poisoned rat model. Method: Fifty five rats of Sprague-Dawley strain were divided into three groups: control group, only intraperitoneally injected saline; paraquat group, single dose intraperitoneally injected paraquat(24.5%, 40 mg/kg) and every 8 hours injected saline; paraquat and vitamin C group, single dose intraperitoneally injected paraquat(24.5%, 40 mg/kg) and every 8 hours injected vitamin C(72 mg/kg). Rats were sacrificed on the 12 hours, 1st day, 2nd day, 4th day, 7th day after injection and liver tissue was obtained. H&E(Hematoxylin & Eosin) stain and Masson's trichrome stain for collagen fiber detection were undertaken. The results were observed using the microscope. Results: 1. There were no differences between control and experimental group at the 12hours after regular injection of high dose vitamin C. 2. There were significantly decreased liver damage in experimental group in the 1st day after regular injection of high dose vitamin C. 3. There were significantly increased recovery of liver damage with time in experimental group after regular injection of high dose vitamin C. Conclusion: These results suggest that regular injection of high dose vitamin C is effective in decreasing liver damage in paraquat intoxication.

• Journal of Radiation Protection and Research
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• v.40 no.4
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• pp.244-251
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• 2015

The containment filtered venting system reduces the range of the contamination area around the nuclear power plant by strengthening the integrity of the containment building. In this study, the probabilistic assessment code MACCS2 was used to assess the effect of the CFVS to off-site. The accident source term was selected from a Probabilistic Safety Analysis report of SHINKORI 1&2 Nuclear Power Plant. The three source term categories from 19 STC were chosen to evaluate the effective dose and thyroid dose of residents around the power plant and the dose with CFVS and without CFVS were compared. The dose was calculated according to the distance from the nuclear power plant, so the damage scale based on the distance that exceeds the IAEA criteria for effective dose (100 mSv per 7 days) and thyroid dose (50 mSv per 7 days) were compared. The effective dose reduction rates of the STC-3, STC-4, STC-6 were about 95-99% in the whole range (0~35 km), 96-98% for the thyroid dose. There are similar results between effective dose and thyroid dose. After applying the CFVS, the damage scale that exceeds the effective dose criteria was about 1 km (mean). Especially, the STC-4 damage scale was decreased from 26 km (mean) to 1.2 km (mean) significantly. The damage scale that exceed the thyroid dose criteria was decreased to 2~3 km (mean). The STC-4 damage scale was also decreased significantly as compared to STC-3, STC-6 in terms of effective dose.

• The Korea Journal of Herbology
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• v.34 no.1
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• pp.43-50
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• 2019

Objectives : The purpose of this study was to proofread 'one ryang' in the Decoction of ${\ll}$Treatise on Cold Damage Diseases${\gg}$. Methods : I found out the ratio of maximum dose and minimum dose in this book. On the basis of the ratio, I corrected 'one ryang' in diverse decoctions. Results : In any decoction, maximum dose of medicinal medica in one decoction could not exceed four times minimum dose. Specifically, in the case that maximum dose in one decoction is sixteen ryang, it could not exceed eight times minimum dose in the same decoction. Any medicinal medica used in two decoctions or more, its maximum dose could not exceed four times minimum dose in other decoctions. On the basis of these results, it should be changed into three ryangs that are one ryang dose of 'Haematitum' of Seonbokdaeja Tang, 'Ginger' of Bujageongang Tang, Baektong Tang, Baektonggajeodamjep Tang and Senggangsasim Tang. Furthermore it should be changed into two ryangs that are one ryang dose of 'Coptidis Rhizoma' of Sohamhyung Tang, 'Ginger' of Dowha Tang, 'Ginseng Radix' of Whubaksenggangbanhagamchoinsam Tang, 'Polyporus, Poria Sclerotium, Alismatis Rhizoma, Talcum and Asini Corii Colla' of Jeoryeong Tang, 'Cimicifugae Rhizoma, Atractylodis Rhizoma Alba and Anemarrhenae Rhizoma' of Mahuangshengma Tang and 'Cassiae Cortex Interior' of Gyejigamchoryonggolmoryeo Tang. Conclusions : These results suggest that one ryang of thirteen medicinal medica such as Haematitum or Ginger of eleven decoctions such as Seonbokdaeja Tang or Bujageongang Tang should be changed into two or three ryangs.