• Title/Summary/Keyword: Damage Depth

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An Experimental Study on the Effect of Combined X-ray and Microwave Hyperthermia on the Rectum and Urinary Bladder of Rats (흰쥐의 직장과 방광에 X-선 조사와 마이크로파 온열요법의 효과에 관한 실험적 연구)

  • Lee, Kyung-Ja;Rhee, Chung-Sik
    • Radiation Oncology Journal
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    • v.4 no.2
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    • pp.115-128
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    • 1986
  • Hyperthermia can enhance the radiation effect as a synergistic reaction in combined X-ray irradiation and hyperthermia; hyperthermia sensitize radioresistant S-phase cells and inhibit cellular recovery from sublethal damage. We fabricated 100 watts, 2450 MHz microwave applicator for hyperthermia and planned the method and condition of heating and measured the temperature by using Agar phantom as a preliminary test. For biological examination, 102 rats were divided into 4 groups as hyperthermia, X-ray irradiation (6Gy-15Gy), combined X-ray and hyperthermia, and normal control groups. Microscopic examination of the rectum and bladder was done and the results were as followings: 1. The microwave generator with 100 watts, 2450MHz magnetron could be heating up to $40^{\circ}{\sim}50^{\circ}C$ for one hour in living tissue. 2. The thermal distribution in tissue equivalent phantom with microwave can be maintained at $40^{\circ}{\sim}44^{\circ}C$ in area of 3cm in depth and 2-10cm in diameter. 3. In Hyperthermia alone group, there was submucosal edema of the rectum but no histologic change in the urinary bladder was seen. 4. The minimal necrosis of the mucosa was appeared in the rectum and bladder after 15 days of 6 Gy and 8 Gy irradiation respectively. The minimal necrosis of the muscle layer of rectum and bladder was appeared after 15 days of 8Gy and 60days of 10Gy irradiation respectively. 5. In combined group of radiation and hyperthermia, thermal enhancement ratio (calculated at necrosis of mucosa and muscle layer) of rectum and bladder was 1.0, and it suggest that there is no change of tolerance dose of normal rectum and bladder.

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General Pharmacology of G009, a Polysaccharide Isolated from Ganoderma lucidum IY 009 (영지의 단백다당체 G009의 일반약리작용)

  • Lee, Eun-Bang;Cheon, Seon-Ah;Kim, Sang-Mee;Kim, Kyung-Ran;Kim, Su-Ung;Lee, Seung-Yong;Lee, seung-Mok;Jeong, Hoon;Hyun, Ik-Sang;Lee, June-Woo;Han, Man-Deuk
    • Biomolecules & Therapeutics
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    • v.2 no.4
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    • pp.369-375
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    • 1994
  • A polysaccharide, G009, isolated from Ganoderma lucidum IY 009, was subjected to investigating on general pharmacology. This material at the large oral doses of 1000 and 2000 mg/kg in mice did not exhibit any abnormal behaviors and another effects on central nervous system. It also had no influences on hexobarbital-induced sleeping time, rotarod test and spontaneous activity test at each oral dose of 1000 mg/kg in mice. No effects on the body temperature and on acetic acid induced writhing syndrome in mice were observed with its oral administration at 1000 mg/kg, and the convulsions induced by strychnine and pentetrazole were not inhibited at its oral doses of 1000 mg/kg in mice. The solution of G009 as given intravenously at the doses of 30 and 60 mg/kg in rabbit had no influences on blood pressure and respiration rates and depth. In isolated organs of rat uterus and fundus muscles and guineapig ileum and trachea, it did not show any contraction or relaxation at the concentrations of 2$\times$10$^{-3}$ g/ml, and the contractive actions produced by oxytocin, acetylcholine, serotonin and histamine were not inhibited at the same doses. This material showed no effect on intestinal propulsion test in mice and gastric secretion in rats at the oral doses of 1000 mg/kg. However, it is interesting that the material exhibited potent inhibition of acidified aspirin induced gastric damage at the doses of 500 and 1000 mg/kg in rats.

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An Experimental Study on the Thermal Property of Concrete under the Load Ratio Condition in Fire (화재시 하중재하에 따른 콘크리트의 열적특성에 관한 실험적 연구)

  • Kim, Hyung-Jun;Kim, Heung-Youl;Park, Kyung-Hun;Jung, Jae-Young;Kwan, Ki-Hyuk
    • Fire Science and Engineering
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    • v.23 no.6
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    • pp.66-74
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    • 2009
  • When a fire occurs, the concrete structure's strength decreases by the increasing temperature under the fire in certain condition of constant load. And, the ratio of the axial force is changed by such decreased strength so that the structure is deformed. In this research, considering such case, we have conducted an actual fire test for the concrete lining with constant loading condition and various fire conditions. The specimen adopts the shape condition for small practical specimen defined by the EFNARC and we used 24MPa, 40MPa and 50MPa to analyze the thermal properties by the strength. The ratio of loading is imposed by a certain loading condition based on 20% and 40% of the sectional stress in concrete and MHC Fire is selected to realize the thermal impact of the concrete by rapid increasing temperature. As the result of the experiment, in the same ratio of loading, the 50MPa specimen shows more cracks and spalling as time goes on. The area damaged by the fire, according to the functional criteria of the concrete lining under the fire in ITA, does not satisfy with the standard in lack of 50mm depth from the heating surface at total 200mm lining.

A Study on the Peak Runoff Reduction Effect of Seolleung·Jeongneung Zone by Applying LID(Low Impact Development) System based on the Landscape Architectural Technology (조경기술기반 LID 시스템 적용을 통한 선릉·정릉 권역의 첨두유출량 분석)

  • Kim, Tae-Han;Choi, Jong-Hee
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.35 no.4
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    • pp.126-133
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    • 2017
  • This study analyzed hydrological changes of stormwater runoff of Seolleung Jeongneung zone according to the application of LID system based on landscape Architectural technology. The results are as follows. First, when flooding occurred in Gwanghwamun in July 27, 2011, the maximum instantaneous rainfall amount was 183 mm/hr recorded at 10:00 on 27th for 10 minutes, and it was confirmed that rainfall intensity more than three times as high as the maximum rainfall of 57.5 mm/hr. Second, it is possible to control peak flow rate in the case of 1,500mm of soil thickness, so that it is possible to improve the vulnerability of flood damage in Seolleung and Jeongneung zone when applying the LID system. Third, in the berm height scenario, peak flow rate control was not controled in all depth level models, but the first stormwater runoff was delayed by 4 hours and 10 minutes compared to the soil thickness scenario. It was interpreted as a relatively important indicator the soil thickness for the initial stromwater runoff reduction and the berm height for the peak runoff. Through this, the systematic adaptation of landscape-friendly ecological factors within the cultural property protection zone could theoretically confirm the effects of flood disaster prevention.

A Study on Smart Ground Resistance Measurement Technology Based on Aduino (아두이노 기반 IT융합 스마트 대지저항 측정 기술 연구)

  • Kim, Hong Yong
    • Journal of the Society of Disaster Information
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    • v.17 no.4
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    • pp.684-693
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    • 2021
  • Purpose: The purpose is to establish a safe facility environment from abnormal voltages such as lightning by developing a smart land resistance measuring device that can acquire real-time land resistance data using Arduino. Method: This paper studied design models and application cases by developing a land resistance acquisition and analysis system with Arduino and a power line communication (PLC) system. Some sites in the wind power generation complex in Gyeongsangnam-do were selected as test beds, and real-time land resistance data applied with new technologies were obtained. The electrode arrangement adopted a smart electrode arrangement using a combination of a Wenner four electrode arrangement and a Schlumberger electrode arrangement. Result: First, the characteristic of this technology is that the depth of smart multi-electrodes is organized differently to reduce the error range of the acquired data even in the stratigraphic structure with specificity between floors. Second, IT convergence technology was applied to enable real-time transmission and reception of information on land resistance data acquired from smart ground electrodes through the Internet of Things. Finally, it is possible to establish a regular management system and analyze big data accumulated in the server to check the trend of changes in various elements, and to model the optimal ground algorithm and ground system design for the IT convergence environment. Conclusion: This technology will reduce surge damage caused by lightning on urban infrastructure underlying the 4th industrial era and design an optimized ground system model to protect the safety and life of users. It is also expected to secure intellectual property rights of pure domestic technology to create jobs and revitalize our industry, which has been stagnant as a pandemic in the post-COVID-19 era.

Estimation of Inundation Area by Linking of Rainfall-Duration-Flooding Quantity Relationship Curve with Self-Organizing Map (강우량-지속시간-침수량 관계곡선과 자기조직화 지도의 연계를 통한 범람범위 추정)

  • Kim, Hyun Il;Keum, Ho Jun;Han, Kun Yeun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.6
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    • pp.839-850
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    • 2018
  • The flood damage in urban areas due to torrential rain is increasing with urbanization. For this reason, accurate and rapid flooding forecasting and expected inundation maps are needed. Predicting the extent of flooding for certain rainfalls is a very important issue in preparing flood in advance. Recently, government agencies are trying to provide expected inundation maps to the public. However, there is a lack of quantifying the extent of inundation caused by a particular rainfall scenario and the real-time prediction method for flood extent within a short time. Therefore the real-time prediction of flood extent is needed based on rainfall-runoff-inundation analysis. One/two dimensional model are continued to analyize drainage network, manhole overflow and inundation propagation by rainfall condition. By applying the various rainfall scenarios considering rainfall duration/distribution and return periods, the inundation volume and depth can be estimated and stored on a database. The Rainfall-Duration-Flooding Quantity (RDF) relationship curve based on the hydraulic analysis results and the Self-Organizing Map (SOM) that conducts unsupervised learning are applied to predict flooded area with particular rainfall condition. The validity of the proposed methodology was examined by comparing the results of the expected flood map with the 2-dimensional hydraulic model. Based on the result of the study, it is judged that this methodology will be useful to provide an unknown flood map according to medium-sized rainfall or frequency scenario. Furthermore, it will be used as a fundamental data for flood forecast by establishing the RDF curve which the relationship of rainfall-outflow-flood is considered and the database of expected inundation maps.

A Field Test on Bearing Capacity Characteristics of Materials for Ground Cavity Restoration Based on Plate Bearing Test (평판재하시험을 이용한 공동 복구재료의 지지특성에 관한 현장실험)

  • Park, Jeong-Jun;Shin, Heesoo;Kim, Dongwook;You, Seung-Kyong;Yun, Jung-Mann;Hong, Gigwon
    • Journal of the Korean Geosynthetics Society
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    • v.17 no.4
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    • pp.293-304
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    • 2018
  • This paper described a results of field test based on plate bearing test of the restoration material, which was developed to restore the ground cavity due to sewerage damage. The analysis of bearing capacity characteristics on the restoration materials was performed by experimental results. The results showed that the load bearing capacity in the maximum stress condition of the foundation ground is about 66%-70%, when the expansion mat is embedded at the bottom of 0.1 m and 0.2 m from the ground surface. However, The load bearing capacity of expansion mat according to embedded depth was not large. The load bearing capacity of concrete mats was about 82%-90% compared with that of ground surface, and it showed about 50% of the load bearing capacity compared with the expansion mat. As a result of analysis of allowable bearing capacity according to restoration materials, it was confirmed that the allowable bearing capacity of the expansion mat and the concrete was about 130%-150% and about 160% more than the foundation ground, respectively.

Application of dual drainage system model for inundation analysis of complex watershed (복합유역의 침수해석을 위한 이중배수체계 유출모형의 적용)

  • Lee, Jaejoon;Kwak, Changjae;Lee, Sungho
    • Journal of Korea Water Resources Association
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    • v.52 no.4
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    • pp.301-312
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    • 2019
  • The importance of the dual drainage system model has increased as the urban flood damage has increased due to the increase of local storm due to climate change. The dual drainage model is a model for more accurately expressing the phenomena of surface flow and conduit flow. Surface runoff and pipe runoff are analyzed through the respective equations and parameters. And the results are expressed visually in various ways. Therefore, inundation analysis results of dual drainage model are used as important data for urban flood prevention plan. In this study, the applicability of the COBRA model, which can be interpreted by combining the dual drainage system with the natural watershed and the urban watershed, was investigated. And the results were compared with other dual drainage models (XP-SWMM, UFAM) to determine suitability of the results. For the same watershed, the XP-SWMM simulates the flooding characteristics of 3 types of dual drainage system model and the internal flooding characteristics due to the lack of capacity of the conduit. UFAM showed the lowest inundation analysis results compared with the other models according to characteristics of consideration of street inlet. COBRA showed the general result that the flooded area and the maximum flooding depth are proportional to the increase in rainfall. It is considered that the COBRA model is good in terms of the stability of the model considering the characteristics of the model to simulate the effective rainfall according to the soil conditions and the realistic appearance of the flooding due to the surface reservoir.

Characteristics of the spatio-temporal distributions of water quality and phytoplankton communities in the Isa Stream systems (ISS) (이사천 수계의 수질환경과 식물플랑크톤 군집의 시·공간적 분포 특성)

  • Park, Jong Sick;Cheong, Cheong-Jo;Yoon, Yang Ho
    • Korean Journal of Environmental Biology
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    • v.39 no.3
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    • pp.273-288
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    • 2021
  • We analyzed the spatio-temporal distribution characteristics of water quality and phytoplankton communities in the Isa Stream systems (ISS) from Sangsa Lake to Suncheon Bay. Sangsa Lake showed relatively oligotrophic and mesotrophic conditions, but the freshwater and mixed brackish water zones showed more severe eutrophication than Sangsa Lake and Suncheon Bay due to the influence of industrial waste such as livestock waste. In terms of the phytoplankton community, the number of phytoplankton species was higher in freshwater and mixed brackish water zones than in Sangsa Lake and Suncheon Bay, but the cell density and Chlorophyll-a concentrations (Chl-a) were relatively high in Sanga Lake and Suncheon Bay. In particular, the mesotrophic species Fragilaria crotonensis and Asterionella formosa showed different dominance in the surface and bottom layers, and the influence of A. formosa was significant in the freshwater and mixed brackish water zones in spring and summer. However, Skeletonema costatum-ls, a eutrophic indicator species, dominated in mixed brackish water zones to seawater in autumn and winter. Thus, the severe eutrophication and rapid environmental changes in the ISS could seriously damage the coastal ecosystem in Suncheon Bay. These ecosystem changes are threatening in terms of conservation and management of the UNESCO Suncheon Biosphere Reserve and Yeoja Bay including Suncheon Bay, which recorded the first Ramsar wetland in Korea. Therefore, further research is needed to establish an in-depth management plan.

A Qualitative Study on the Drinking Experience of Participants in Self-Sufficiency Program with Alcohol Problems (음주문제가 있는 자활근로사업 참여자의 음주경험에 관한 질적연구)

  • Lee, Eun-Hee
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.723-737
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    • 2021
  • This study attempted to understand the meaning and nature of the drinking experience of participants participating in self-sufficiency program with alcohol problems. For this, data were collected by conducting in-depth interviews with seven problem drinkers currently participating in the self-support work project at the local self-support center. It was analyzed by a phenomenological analysis method. As a result of the study, 26 topics, 7 thematic vowels, and 3 categories were derived. The essential meaning of the study participant's drinking experience is as follows. It turned out to be 'a sense of accomplishment and belonging to job performance', 'extension of work life', 'maintaining social relations', 'weekly control drinking for self-support', 'minimum effort not to damage the working environment', 'self-criticism and reflection on absence from work resulting from heavy drinking', 'self-awareness of drinking problems. Through the analysis, the participants drank with a sense of accomplishment and a sense of belonging to job performance, and drinking was considered to extend their work life and maintain social relationships. At the same time, on weekdays when participating in self-support work projects, they we refrain from drinking in their own way and make minimal efforts not to interfere with the working environment under a hangover. The Absent from work due to heavy drinking led to self-reflection and furthermore, it was confirmed that they were aware of their problem drinking.