• 한국수자원학회논문집
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• 제54권6호
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• pp.381-393
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• 2021

국립재난안전연구원의 재난안전 신기술 공적개발원조(ODA) 사업의 일환으로 2019년 라오스 볼리캄싸이주 남싼강유역의 보리칸을 대상으로 홍수예경보시스템을 구축하였다. 미계측 중소하천유역인 대상 지역에 강우량와 유출량의 실시간 관측을 위한 관측소 및 경보국을 설치하였으며, 실시간 자료 관리와 홍수예경보 기능 등을 수행하는 소프트웨어도 개발되었다. 홍수경보 기준 설정 및 홍수예측을 위한 nomograph 개발을 위해 대상 지역의 30년 치 연도별 최대 일강우량자료와 하천측량성과를 바탕으로 수리·수문분석을 수행하였다. 본 논문은 시스템 구축 과정과 방법론을 소개하고, 시스템 설치 후 2020년 실시간 관측 수집된 자료들을 바탕으로 수행한 시스템의 적용성 검토 결과를 제시하였다.

• 한국물환경학회지
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• 제27권4호
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• pp.509-515
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• 2011

For this study the 4 sub-watersheds Okdong A, Hankang B, Jecheon A and Hankang C which are the main streams of the Han River within the mid-level region of Chungju Dam are selected and the analysis of soils has been carried out through the soil basic survey. When it comes to the soil erosion amount the soil nutrient load has been calculated by utilizing the RUSLE erosion equation. In case of the data related to the measurement of water flow and quality the information available from the "Water Information System" one of the websites run by the Ministry of Environment has been used to calculate the water pollution load. The correlation between the soil nutrient load and the water pollutant load has been analyzed through making comparison. According to the results related to the soil nutrient load of each sub-watershed the Hankang C shows the highest values TOC 29,986.92 ton/yr, TN 3,860.33 ton/yr and TP 973.97 ton/yr respectively. Even when it comes to the loads related to water quality the Hankang C shows also comparatively high values TOC 6,625.64 ton/yr, TN 7,335.01 ton/yrand TP 145.49 ton/yr respectively. The soil nutrient loads of the sub-watersheds are shown to increase towards the lower stream meaning the load increases in the order of Hankang CHankang B and Okdong A. When it comes to the water pollutant load the value goes up along down the water system meaning the load gets higher in the order of Hankang C, Hankang B and Okdong A while utilizing the mainstream within the mid-level region of Chungju Dam as the basis. The correlation study showed that the nutrient content of soil is proportional to the pollutant load in water with the strongest positive correlation with TOC.

• 치위생과학회지
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• 제21권1호
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• pp.1-7
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• 2021

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted primarily through droplets, and dental practitioners are at risk of occupational exposure to SARS-CoV-2 infection owing to direct contact with the patient's mouth, aerosols from dental procedures, and saliva. Wearing a mask is believed to be the best method of protection against infection, and a systematic literature review was conducted on whether the dental masks used in dentistry are effective in preventing Coronavirus Infectious Disease-19 (COVID-19). Methods: We used PubMed, Google Scholar, DBpia, NDSL, and KISS databases for this study. Of the 917 documents narrowed down by the search terms "Coronavirus, COVID-19, and dental," 83 documents were collected and studied. Ultimately, 42 of these papers were selected for analysis after considering duplication from the flow chart of the literature selection process. Results: While dental masks are often used when treating patients with unknown COVID-19 status, the Ministry of Food and Drug Safety stated that the use of dental masks is insufficient in preventing cross-transmission of COVID-19; instead, it was recommended that N95 masks, which correspond to KF94 masks, should be worn daily. On the other hand, wearing a dental mask and following precautions such as hand hygiene may not pose a significantly higher risk of infection than wearing an N95 mask when treating COVID-19 patients. Conclusion: There is an ongoing discussion regarding the use of dental masks when treating dental patients, and many argue that different types of masks should be selected according to the degree of infection and the individual's respiratory condition. By considering the safety and efficacy of dental masks in preventing infection, improvements can be made in the management of COVID-19 and dental-related infections.

• 중환자간호학회지
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• 제15권3호
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• pp.115-127
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• 2022

Purpose : This study aimed to investigate sleep parameters and to identify differences according to respiratory support therapy, sedation, and pain medication in intensive care unit (ICU) patients. Methods : In this observational study, sleep parameters were measured using actigraphy. We observed 45 sleep events in 30 ICU patients receiving respiratory support therapy. We measured the sleep parameters, time, efficiency, and wakefulness after sleep onset (WASO). The differences in sleep parameters according to the respiratory support therapy were analyzed using the Mann-Whitney U test. Results : The average daily sleep time of the participants was 776.66±276.71 minutes, of which more than 60% accounted for daytime sleep. During night sleep, the duration of WASO was 156.93±107.91 minutes, and the frequency of WASO was 26.02±25.82 times. The high flow nasal cannula (HFNC) group had a significantly shorter night sleep time (𝑥²=7.86, p =.049), a greater number of WASO (𝑥²=5.69, p =.128), and a longer WASO duration (𝑥²=8.75, p =.033) than groups of other respiratory therapies. Conclusion : ICU patients on respiratory support therapy experienced sleep disturbances such as disrupted circadian rhythm and sleep fragmentation. Among respiratory support regimens, HFNC was associated with poor sleep parameters, which appears to be associated with the insufficient use of analgesics. The results of this study warrant the development of interventions that can improve sleep in ICU patients receiving respiratory support, including HFNC.

• Journal of Ginseng Research
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• 제45권6호
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• pp.744-753
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• 2021

Background: Gintonin-enriched fraction (GEF) is a new non-saponin component glycolipoprotein isolated from ginseng root. This study examined the effect of GEF on age-related sarcopenia in old C57BL/6J mice. Methods: Young (3-6 months) and old (20-24 months) C57BL/6J mice received oral GEF (50 mg/kg/day or 150 mg/kg/day) daily for 5 weeks. During the oral administration period, body weight and grip strength were measured weekly. After sacrifice, muscles from the hindlimb were excised and used for hematoxylin and eosin staining and western blotting to determine the effects of GEF on sarcopenia. The thymus was photographed to compare size, and flow cytometry was performed to examine the effect of GEF on immune homeostasis in the thymus and spleen. Blood samples were collected, and the concentrations of pro-inflammatory cytokines and IGF-1 were measured. Results: GEF caused a significant increase in muscle strength, mass, and fiber size in old mice. GEF restored age-related disruption of immune homeostasis by maintaining T cell compartments and regulating inflammatory biomarkers. Thus, GEF reduced common low-grade chronic inflammatory parameters, which are the main cause of muscle loss. Conclusion: GEF maintained immune homeostasis and inhibited markers of chronic inflammation, resulting in anti-sarcopenia effects in aged C57BL/6J mice. Thus, GEF is a potential therapeutic agent that slows sarcopenia in the elderly.

• Journal of Ginseng Research
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• 제46권6호
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• pp.809-818
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• 2022

Background: The non-saponin fraction (NSF) of Korean Red Ginseng is a powder in which saponin is eliminated from red ginseng concentrate by fractionation. In this study, we examined the effect of NSF on age-associated sarcopenia in old mice. Methods: NSF (50 or 200 mg/kg/day) was administered orally daily to young (3-6-month-old) and old (20-24-month-old) C57BL/6 J mice for 6 weeks. Body weight and grip strength were assessed once a week during the oral administration period. The gastrocnemius and quadriceps muscle were excised, and the muscle fiber size was compared through hematoxylin and eosin staining. In addition, the effect of NSF on sarcopenia and inflammation/oxidative stress-related factors in hindlimb muscles was investigated by western blotting. Flow cytometry analysis was conducted to investigate the effect of NSF on immune homeostasis. Blood samples were collected by cardiac puncture, and the serum levels of insulin-like growth factor 1, pro-inflammatory cytokines, and glutathione were evaluated. Results: NSF significantly alleviated muscle strength, mass, and also fiber size in old mice. Age-associated impairment of immune homeostasis was recovered by NSF through retaining CD11b⁺F4/80⁺ macrophages and regulating inflammatory biomarkers. NSF also decreased the age-induced expression of oxidative stress factors. Taken together, NSF showed the effect of improving sarcopenia by inhibiting low-grade chronic inflammatory/oxidative stress factors. Conclusion: NSF exhibited anti-sarcopenia effects by regulating chronic inflammation and oxidative stress in old mice. Thus, we suggest that NSF is a promising restorative agent that can be used to improve sarcopenia in the elderly as well as maintain immune homeostasis.

• 한국정보통신학회논문지
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• 제25권11호
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• pp.1649-1654
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• 2021

본 논문에서는 고령자의 낙상상황을 감지할 수 있는 텐서플로우 장단기 메모리 기반 낙상감지 시스템의 정규화에 대하여 소개한다. 낙상감지는 고령자의 몸에 부착한 3축 가속도 센서 데이터를 사용하며, 총 7가지의 행동 패턴들에 대하여 학습하며, 각각 4가지는 일상생활에서 일어나는 패턴이고, 나머지 3가지는 낙상에 대한 패턴이다. 학습시에는 손실함수(loss function)를 효과적으로 줄이기 위하여 정규화 과정을 진행하며, 정규화 과정은 데이터에 대하여 최대최소 정규화, 손실함수에 대하여 L2 정규화 과정을 진행한다. 3축 가속도 센서를 이용하여 구한 다양한 파라미터에 대하여 정규화 과정의 최적의 조건을 제시한다. 낙상 검출율면에서 SVM을 이용하고 정규화 127과 정규화율 λ 0.00015일 때 Sensitivity 98.4%, Specificity 94.8%, Accuracy 96.9%로 가장 좋은 모습을 보였다.

• 한국수산과학회지
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• 제55권4호
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• pp.449-454
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• 2022

The oxygen consumption rate (OCR) based on the water temperature and body size of the sea squirt Halocynthia roretzi was examined to provide quantitative information about the metabolic response of the species. OCRs were measured using a closed flow-through respirometer at four different water temperatures (10, 15, 20 and 25℃) and two different body sizes (21.4±1.1 g and 150.5±1.3 g, wet weight) with triplicates of each treatment. OCR increased as water temperature increased at both body sizes, but decreased as body size increased regardless of the water temperature (P<0.001). The effect of body size evaluated as a power function ranged from 0.8055 to 0.8884. The highest Q₁₀ values in the small and large size groups ranged from 15 to 20℃ and 20 to 25℃, respectively. The metabolic daily energy loss rate via respiration at all tested temperatures ranged from 56.2 to 106.1 J g^-1 d^-1 in the small-size group and from 44.5 to 92.0 J g^-1 d^-1 in the large-size group. Our results indicate that the metabolic response of H. roretzi highly depends on fluctuating water temperature at a given life stage.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.142-142
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• 2023

Humans inevitably and continuously produce wastewater in daily life worldwide. To decrease the degradation of river water bodies and aquatic ecosystem therein, humans have built systems at different scales to collect, drain, and treat household-produced wastewater. Particularly, municipal wastewater treatment plants (WWTPs) with centralized controls have played a key role in reducing loads of nutrients in domestic wastewater for the last few decades. Notwithstanding such contributions, impaired rivers regarding water quality and habitat integrity still exist at the whole river basin scale. It is highly attributable to the absence of dilution capacity of receiving streams and/or the accumulation of the pollutant loads along flow paths. To improve the perspective for individual WWTPs assessment, the first crucial step is to achieve systematic understanding on spatial distribution characteristics of all WWTPs together in a given river basin. By taking the initiative, our former study showed spatial hierarchical distributions of WWTPs in three large urbanized river basins in Germany. In this study, we uncover how municipal WWTPs in the contiguous United States are distributed along river networks in a give river basin. The extended spatial scope allows to deal with wide ranges in geomorphological attributes, hydro-climatic conditions, and socio-economic status. Furthermore, we identify the relation of the findings with multiple factors related to human activities, such as the spatial distribution of human settlements, the degree of economy development, and the fraction of communities served by WWTPs. Generalizable patterns found in this study are expected to contribute to establishing viable management plans for recent water-environmental challenges caused by WWTP-discharges to river water bodies.

• 한국수자원학회논문집
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• 제56권1호
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• pp.1-9
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• 2023

현재까지는 연중 하천유량의 관리기간은 홍수기와 비홍수기로 구분하고, 관리해야 할 유량의 범위는 갈수량에서 홍수량까지로 폭넓게 규정하고 있다. 본 연구에서는 4대강 8개 지점의 장기간 일평균유량 자료를 이용하여1년을 유량의 분산과 평균이 동질한 기간들로 구분하고, 기간별 유량의 평균과 표준편차를 이용하여 유량의 관리범위를 설정하는 방안을 제시한다. 연구결과, 연중 관리기간은 지점에 따라 차이는 있으나 홍수기 이전, 홍수기, 홍수기 이후로 구분할 수 있었으며, 기간을 세분화하면 최소유량에 대한 최대유량의 비도 낮아지는 것을 알 수 있었다. 또한, 연중 일평균유량이 갈수량 이상 홍수량 이하가 되도록 기간별 일평균유량의 관리범위를 기간별 일평균유량의 평균 ±표준편차로 설정하는 방안도 제시하였다.