• 약학회지
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• 제57권2호
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• pp.119-124
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• 2013

The aim of this present study was to investigate the antifungal effect of tanshinones isolated from Salvia miltiorrhiza against Candida ablicans, a polymorphic fungus. For the work, tanshinone IIA (TSN), cryptotanshinone (CTS), and dihydrotanshinone I (DTS) were chosen. Initially, their antifungal effect was analyzed by in-vitro susceptibility test. Data from the susceptibility test showed that while all of these three compounds had antifungal activity, DTS was the most potent. At $100{\mu}g$ DTS/ml, there was about 80% CFU (colony forming unit) reduction as compared to DTS-untreated C. albicans yeast cells (P<0.05). Thus, DTS was selected to determine its antifungal activity in a murine model of disseminated candidiasis due to C. albicans. Results showed that DTS enhanced resistance of mice against disseminated candidiasis. During the entire period of 30-day observation, 60% of DTS-given mice groups survived whereas control animals all died within 14 days (P<0.05). Moreover, DTS inhibited the hyphal production, one of the virulence factors of this fungus, from the blastoconidial form of the fungus. Therefore, the tanshinone appears to have antifungal activity specific for C. albicans infection, which could possibly be mediated by the blockage of hyphal production.

• KSBB Journal
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• 제26권5호
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• pp.433-438
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• 2011

These studies were conducted to investigate the alcohol degradation effects of the extract of herbal composition (DTS20) containing Viscum album L., Lycium chinense L., Inonotus obliquus and Acanthopanax senticosus H., on the alcohol administered mice. To investigate anti-hangover effect, alcohol and alcohol dehydrogensae (ADH) concentration of blood were measured after oral administration of ethanol. The administration of DTS20 (200-500 mg/kg) had beneficial actions toward alcohol degradation in acute alcohol treated mice model. The oral administration of DTS20 showed decreased gastric mucous membrane damage produced in ethanol treated mice. In addition, intraperitoneal administration of DTS20 showed anti-inflammatory effects in inhibition tests of vascular permeability produced by acetic acid. DTS20 also reduced the concentration of nitric oxide (NO), tumor necrosis factor (TNF)-${\alpha}$ in macrophages that were activated by LPS. These results demonstrate that DTS20 possesses potential to stimulate the alcohol degradation and inhibit the inflammatory effects in mice.

• Korean Journal of Radiology
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• 제22권12호
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• pp.2026-2033
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• 2021

Objective: The aim of this study was to compare the diagnostic performances of digital tomosynthesis (DTS) and conventional radiography in detecting osteonecrosis of the femoral head (ONFH) using computed tomography (CT), as the reference standard and evaluate the diagnostic reproducibility of DTS. Materials and Methods: Forty-five patients (24 male and 21 female; age range, 25-77 years) with clinically suspected ONFH underwent anteroposterior radiography, DTS, and CT. Two musculoskeletal radiologists independently evaluated the presence and type of ONFH. The diagnostic performance of radiography and DTS in detecting the presence of ONFH and determining the types of ONFH were evaluated. The interobserver and intraobserver reliabilities of each imaging modality were analyzed using Cohen's kappa. Results: DTS had higher sensitivity (89.4%-100% vs. 74.5%-76.6%) and specificity (97.3%-100% vs. 78.4%-83.8%) for ONFH detection than radiography. DTS showed higher performance than radiography in identifying the subtypes of ONFH with statistical significance in one reader (type 1, 100% vs. 30.8%, p = 0.004; type II, 97.1% vs. 73.5%, p = 0.008). The interobserver agreement was excellent for DTS and moderate for radiography (kappa of 0.86 vs. 0.57, respectively). The intraobserver agreement for DTS was higher than that of radiography (kappa of 0.96 vs. 0.69, respectively). Conclusion: DTS showed higher diagnostic performance and reproducibility than radiography in detecting ONFH. DTS may be used as a first-line diagnostic modality instead of radiography for patients suspected of having ONFH.

• 한국도로학회논문집
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• 제4권1호
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• pp.149-159
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• 2002

본 연구에서는 아스팔트 바인더의 절대점도, 동점도, 침입도, 연화점, PG 고온등급을 이용하여 샌드아스팔트 흔합물의 고속 직접인장강도(DTS1), 저속 직접인장강도(DTS2), 간접인장강도(ITS), 회복탄성계수(MR), 강성지수(SI)를 추정하기 위한 연구를 수행하였다. 여러 가지 혼합물의 특성 중 DTS2가 가장 상관성이 높게 나타났으며 그 다음이 DTS1, ITS, SI, MR 순인 것으로 나타났다. 바인더 성질 중에는 PG 등급이 DTS2와 가장 높은 상관 관계를 보여 PG 고온등급이 높은 바인더를 사용하면 직접인장강도가 어느 정도 우수한 혼합물을 얻을 수 있음을 알 수 있었다. 하지만 각각의 물리적 성질만으로는 신뢰도가 낮아 종합적으로 여러 물성을 이용하여 상관성을 분석하였다. 그 결과 직접 및 간접인장강도는 결정계수가 0.99 이상인 모델을 얻을 수 있었다. 그리고 MR, SI 값의 추정치 모델도 R2이 0.91 및 0.93 이상이어서 상당한 신뢰성을 가지고 물성으로부터 역학적 특성을 추정할 수 있음을 보여준다.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2017년도 추계학술대회
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• pp.185-186
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• 2017

본 논문에서는 최근 논의되고 있는 하이브리드 라디오 방송 기술을 자동차에서 상용화 하기 위해서 개발된 Xperi 사의 DTS Connected Radio 기술을 개략적으로 소개한다. DTS Connected Radio 는 방송망으로 수신된 아날로그 혹은 디지털 라디오와 IP 망을 이용하여 받은 방송 프로그램 정보 및 현재 방송되고 있는 음악에 대한 정보 등의 추가적인 정보를 차량에서 같이 제공하는 서비스를 말한다.

• 한국화재소방학회논문지
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• 제30권4호
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• pp.27-38
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• 2016

본 논문은 현재 국외기술에 의존하고 있는 광센서 선형감지기를 이용한 화재감지시스템인 분산온도감지(DTS) 시스템을 국산화 기술로 개발하기 위한 연구이다. 이에 본 연구에서는 광섬유 내에서 발생되는 빛의 역산란광 중 온도감지에 주로 사용되는 라만산란광의 전기적 신호파형을 오실로스코프를 이용하여 분석하였다. 측정결과 Stokes 신호파형은 온도가 상승해도 변화량이 거의 없었으나, 온도에 민감한 anti-Stokes 신호파형은 상대적으로 그 값이 증가하는 것을 확인할 수 있었다. 그리고 라만산란광을 이용하여 화재를 감지할 수 있는 광중계기 및 광수신기로 구성된 광센서 선형 화재감지시스템인 K-DTS 시스템을 개발하였다. 개발된 K-DTS 시스템에 대하여 차동식 및 정온식 감도시험기를 이용하여 차동식 및 정온식 감지기로서의 감도시험을 진행해 본 결과 형식승인 기준을 만족하고 있는 것을 확인할 수 있었다. 또한, 개발된 K-DTS 시스템의 성능평가를 위해 국외에서 수입되어 가장 많이 사용되고 있는 S-DTS 시스템과 성능비교실험을 진행하였다. 모형터널을 이용한 성능실험결과 화재감지위치 및 화재온도 측정에서 유사한 성능을 나타내는 것을 확인할 수 있었다.

• KEPCO Journal on Electric Power and Energy
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• 제8권2호
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• pp.143-149
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• 2022

As ESS safety issues increase recently, there is a need to more precisely monitor the temperature of the ESS. In this paper, DTS technology for temperature monitoring of ESS batteries is introduced and the temperature measurement principle is explained. The temperature of the battery module is measured using the DTS system, and the thermal deviation between battery cells inside the battery module is analyzed. In order to analyze how thermal imbalance affects the charging and discharging performance of the battery, an accelerated degradation test was conducted. Cycle life characteristics analysis, battery surface temperature change, and AC impedance characteristics were conducted to analyze how the performance of battery cells differs according to temperature conditions.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.284.2-284.2
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• 2002

Gastric contents and blood samples are generally analyzed for the detection of the Drug-toxic substances(DTS) in the postmortem specimens, but tissue specimens from postmortem for the detection of the DTS are, especially, required in the cases that analysis of DTS in blood or gastric contents is impossible because of insufficient or inaccessible specimens in special cases. (omitted)

• 제어로봇시스템학회논문지
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• 제5권4호
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• pp.471-480
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• 1999

This paper presents design and performance improvement of a new digital tomosynthesis (DTS) system for object-detector synchronous rotation. Firstly, a new DTS system, called OSDR (Object-Detector Synchronous Rotation) is suggested and designed to acquire X-ray digital images. Secondly, the shape distortion of DTS images generated by an image intensifier is modeled. And a new synthesis algorithm, which overcomes the limitations of the existing synthesis algorithm, is suggested to improve the sharpness of the synthesized image. Also an artifact analysis of the DTS system is performed. Thirdly, some performance indices, which evaluate quantitatively performance improvement, are defined. And the experimental verification of the performance improvement is accomplished by the ODSR system newly designed. The advantages of the ODSR system are expressed quantitatively, compared with an existing system.

• 한국광학회:학술대회논문집
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• 한국광학회 2006년도 하계학술발표회 논문집
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• pp.129-130
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• 2006