• Title/Summary/Keyword: DTS

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Antifungal Effect of Tanshinone from Salvia miltiorrhiza against Disseminated Candidiasis (Tanshinone 단삼성분의 전신성 캔디다증에 대한 항균효과)

  • Han, Yongmoon;Joo, Inkyung
    • YAKHAK HOEJI
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    • v.57 no.2
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    • pp.119-124
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    • 2013
  • The aim of this present study was to investigate the antifungal effect of tanshinones isolated from Salvia miltiorrhiza against Candida ablicans, a polymorphic fungus. For the work, tanshinone IIA (TSN), cryptotanshinone (CTS), and dihydrotanshinone I (DTS) were chosen. Initially, their antifungal effect was analyzed by in-vitro susceptibility test. Data from the susceptibility test showed that while all of these three compounds had antifungal activity, DTS was the most potent. At $100{\mu}g$ DTS/ml, there was about 80% CFU (colony forming unit) reduction as compared to DTS-untreated C. albicans yeast cells (P<0.05). Thus, DTS was selected to determine its antifungal activity in a murine model of disseminated candidiasis due to C. albicans. Results showed that DTS enhanced resistance of mice against disseminated candidiasis. During the entire period of 30-day observation, 60% of DTS-given mice groups survived whereas control animals all died within 14 days (P<0.05). Moreover, DTS inhibited the hyphal production, one of the virulence factors of this fungus, from the blastoconidial form of the fungus. Therefore, the tanshinone appears to have antifungal activity specific for C. albicans infection, which could possibly be mediated by the blockage of hyphal production.

Effect of Herbal Composition, DTS20 on Alcohol Degradation and Anti-inflammatory Activity (생약 조성물, DTS20의 알코올 분해 및 항염증 효과)

  • Yoon, Taek-Joon;Jo, Sun-Young;Lee, Sue-Jung;Kim, Eun-Young;Shin, Kwang-Soon;Suh, Hyung-Joo
    • KSBB Journal
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    • v.26 no.5
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    • pp.433-438
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    • 2011
  • These studies were conducted to investigate the alcohol degradation effects of the extract of herbal composition (DTS20) containing Viscum album L., Lycium chinense L., Inonotus obliquus and Acanthopanax senticosus H., on the alcohol administered mice. To investigate anti-hangover effect, alcohol and alcohol dehydrogensae (ADH) concentration of blood were measured after oral administration of ethanol. The administration of DTS20 (200-500 mg/kg) had beneficial actions toward alcohol degradation in acute alcohol treated mice model. The oral administration of DTS20 showed decreased gastric mucous membrane damage produced in ethanol treated mice. In addition, intraperitoneal administration of DTS20 showed anti-inflammatory effects in inhibition tests of vascular permeability produced by acetic acid. DTS20 also reduced the concentration of nitric oxide (NO), tumor necrosis factor (TNF)-${\alpha}$ in macrophages that were activated by LPS. These results demonstrate that DTS20 possesses potential to stimulate the alcohol degradation and inhibit the inflammatory effects in mice.

Digital Tomosynthesis versus Conventional Radiography for Evaluating Osteonecrosis of the Femoral Head

  • Yun Hwa Roh;Seunghun Lee;Jeong Ah Ryu;Yeo Ju Kim;Yeesuk Kim;Jiyoon Bae
    • Korean Journal of Radiology
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    • v.22 no.12
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    • pp.2026-2033
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    • 2021
  • Objective: The aim of this study was to compare the diagnostic performances of digital tomosynthesis (DTS) and conventional radiography in detecting osteonecrosis of the femoral head (ONFH) using computed tomography (CT), as the reference standard and evaluate the diagnostic reproducibility of DTS. Materials and Methods: Forty-five patients (24 male and 21 female; age range, 25-77 years) with clinically suspected ONFH underwent anteroposterior radiography, DTS, and CT. Two musculoskeletal radiologists independently evaluated the presence and type of ONFH. The diagnostic performance of radiography and DTS in detecting the presence of ONFH and determining the types of ONFH were evaluated. The interobserver and intraobserver reliabilities of each imaging modality were analyzed using Cohen's kappa. Results: DTS had higher sensitivity (89.4%-100% vs. 74.5%-76.6%) and specificity (97.3%-100% vs. 78.4%-83.8%) for ONFH detection than radiography. DTS showed higher performance than radiography in identifying the subtypes of ONFH with statistical significance in one reader (type 1, 100% vs. 30.8%, p = 0.004; type II, 97.1% vs. 73.5%, p = 0.008). The interobserver agreement was excellent for DTS and moderate for radiography (kappa of 0.86 vs. 0.57, respectively). The intraobserver agreement for DTS was higher than that of radiography (kappa of 0.96 vs. 0.69, respectively). Conclusion: DTS showed higher diagnostic performance and reproducibility than radiography in detecting ONFH. DTS may be used as a first-line diagnostic modality instead of radiography for patients suspected of having ONFH.

Estimation of Mechanical Properties of Sand Asphalt Concrete based on Physical Properties of Binder (결합재의 물리적 성질을 이용한 샌드아스팔트 혼합물의 강도특성 추정)

  • Kim, Kwang-Woo;Lee, Soon-Jae;Lee, Gi-Ho;Lee, Sung-Hoon;Lee, Byung-Duck
    • International Journal of Highway Engineering
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    • v.4 no.1 s.11
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    • pp.149-159
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    • 2002
  • This study was performed to estimate the high-speed direct tensile strength(DTS1), low-speed direct tensile strength(DTS2) , indirect tensile strength(ITS) resilient modulus(MR) and stiffness index(SI) of sand asphalt mixture based on the absolute viscosity, kinematic viscosity, penetration, softening point and PG grade of binder. DTS2 showed higher correlation with the physical properties than other properties of mixture, and the next was DTS1, ITS, SI and MR in order. Among binder properties, PG grade showed the highest relation with DTS2. Therefore. it was found that the high DTS mixture could be made when the binder with a high PG grade was used. However, since the individual physical property showed a relatively low correlation, various properties were used together in regression analysis. The estimation models of DTS and ITS were over 0.99, respectively. R2 of MR and SI estimation models were over 0.91 and 0.93, respectively. It was concluded that mechanical properties could be estimated with a high coefficient of determination from those physical properties.

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DTS Connected Radio - Hybrid Radio Technologies for Automotive (차량용 Hybrid Radio 기술 - DTS Connected Radio)

  • Heo, Jungkwon
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2017.11a
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    • pp.185-186
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    • 2017
  • 본 논문에서는 최근 논의되고 있는 하이브리드 라디오 방송 기술을 자동차에서 상용화 하기 위해서 개발된 Xperi 사의 DTS Connected Radio 기술을 개략적으로 소개한다. DTS Connected Radio 는 방송망으로 수신된 아날로그 혹은 디지털 라디오와 IP 망을 이용하여 받은 방송 프로그램 정보 및 현재 방송되고 있는 음악에 대한 정보 등의 추가적인 정보를 차량에서 같이 제공하는 서비스를 말한다.

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Study on the Development of Optical Sensor Linear Fire Detection System Using Raman Scattering (라만산란을 이용한 광센서 선형 화재감지시스템 개발에 관한 연구)

  • Lee, Gun-Ho;Lim, Woo-Sub;Kim, Si-Kuk
    • Fire Science and Engineering
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    • v.30 no.4
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    • pp.27-38
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    • 2016
  • The paper reports the development of a distributed temperature sensing (DTS) system, which is a fire detection system using optical sensor linear detectors that depends on foreign and domestic technologies. This study accordingly analyzed the electrical signal patterns of Raman scattering light mainly used for temperature sensing among back-scattered light generated in optical fiber by using an oscilloscope. Through the measurement results, it could be verified that the Stokes signal patterns had little change by the temperature increase, but the temperature-sensitive anti-Stokes patterns had relative increase of the changes. This study developed a K-DTS system, which is an optical sensor linear fire detection system composed of an optical repeater and a receiver that can detect fires using Raman scattering light. It could be verified that the developed K-DTS system satisfied the type approval standards through the sensitivity tests using the rate of rise type and fixed temperature type sensitivity testers. In addition, performance experiments have been performed for performance evaluation of the K-DTS system developed in comparison with S-DTS system which has been imported from abroad and widely used in Korea. It can be confirmed from the results of the performance experiments using model tunnels that comparable performances can be obtained in fire detection locations and the measurements of fire temperatures.

DTS-based Temperature Monitoring and Analysis of Battery Cell Deterioration Characteristics by Temperature Condition (DTS 기반 온도 감시 및 온도 조건에서의 배터리 셀 열화 특성 분석)

  • SoonJong, Kwon;Soo-Yeon, Kim;Jin, Hwang;Sang-Kyun, Woo;Bong-Suck, Kim
    • KEPCO Journal on Electric Power and Energy
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    • v.8 no.2
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    • pp.143-149
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    • 2022
  • As ESS safety issues increase recently, there is a need to more precisely monitor the temperature of the ESS. In this paper, DTS technology for temperature monitoring of ESS batteries is introduced and the temperature measurement principle is explained. The temperature of the battery module is measured using the DTS system, and the thermal deviation between battery cells inside the battery module is analyzed. In order to analyze how thermal imbalance affects the charging and discharging performance of the battery, an accelerated degradation test was conducted. Cycle life characteristics analysis, battery surface temperature change, and AC impedance characteristics were conducted to analyze how the performance of battery cells differs according to temperature conditions.

Comparative Studies on the Detection of Drug-Toxic Substances in the Formalin Fixedand Unfixed Tissue Specimens

  • Baeck, Seung-Kyung;Sihn, Young-Sihn;Kim, Sun-Chun;Lee, Bong-Woo
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.284.2-284.2
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    • 2002
  • Gastric contents and blood samples are generally analyzed for the detection of the Drug-toxic substances(DTS) in the postmortem specimens, but tissue specimens from postmortem for the detection of the DTS are, especially, required in the cases that analysis of DTS in blood or gastric contents is impossible because of insufficient or inaccessible specimens in special cases. (omitted)

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Design and Performance Improvement of a Digital Tomosynthesis System for Object-Detector Synchronous Rotation (물체-검출기 동기회전 방식의 X-선 단층영상시스템 설계 및 성능개선에 관한 연구)

  • Kang, Sung-Taek;Cho, Hyung-Suck;Roh, Byung-Ok
    • Journal of Institute of Control, Robotics and Systems
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    • v.5 no.4
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    • pp.471-480
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    • 1999
  • This paper presents design and performance improvement of a new digital tomosynthesis (DTS) system for object-detector synchronous rotation. Firstly, a new DTS system, called OSDR (Object-Detector Synchronous Rotation) is suggested and designed to acquire X-ray digital images. Secondly, the shape distortion of DTS images generated by an image intensifier is modeled. And a new synthesis algorithm, which overcomes the limitations of the existing synthesis algorithm, is suggested to improve the sharpness of the synthesized image. Also an artifact analysis of the DTS system is performed. Thirdly, some performance indices, which evaluate quantitatively performance improvement, are defined. And the experimental verification of the performance improvement is accomplished by the ODSR system newly designed. The advantages of the ODSR system are expressed quantitatively, compared with an existing system.

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