• 제목/요약/키워드: DT&E

검색결과 140건 처리시간 0.022초

Bifidobacterium longum HY8001 균주의 Escherichia coli O157:H7과 Salmonella typhimurium DT104 장곤 내 감염 예방효과 및 Vero cytotoxin 중화효과 (Prophylactic Effects of Bifidobacterium longum HY8001 against Escherichia coli O157:H7 and Salmonella typhimurium DT104 Enteric Infection and Evaluation of Vero Cytotxin Neutralizing Effects)

  • 양수진;윤장원;서근석;구혜정;김소현;배형석;백영진;박용호
    • 한국미생물·생명공학회지
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    • 제27권5호
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    • pp.419-425
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    • 1999
  • Prophylactic effects of Bifidobacterium longum HY8001, Korean isolate, against Escherichia coli O157:H7 and Salmonella typhimurium DT104 enteric infection were examined at four groups of specific pathogen free(SPF)-ICR mouse for each pathogen. B. longum HY8001+B. typhimurium DT104+B. longum HY8001(BL+ST+BL) group and B. longum HY8001+E. coli O157:H7+B. longum HY8001(BL+E+BL) group were fed with B. longum HY8001 before and after E. coli O157:H7 or s. typhimurium DT104 challenge, while B. longum HY8001+S. typhimurium DT104(BL+ST) and B. longum HY8001+e. coli O157:H7(BL+E) groups were fed with B. longum HY8001 only before E. coli O157:H7 or S. typhimurium DT104 challenge. E. coli O157:H7(E) and S. typhimurium DT104(ST) groups were challenged with each pathogen without B. longum HY8001 administration and control groups were administered with phosphate buffered solution(PBS). After the oral administration with B. longum HY8001(109cfu), th emice were challenged with E. coli O157:H7(2$\times$1010cfu) or S. typhimurium DT104(108cfu) and the mortality rate and the fecal shedding of challenged pathogen were also examined define the reactivity of the B. longum HY8001. Production of toxin neutralizing substance(s) of B. longum HY8001 was determined by cell cytotoxicity assay using Vero cells. Fecal shedding of th eS. typhimurium DT104 was significantly decreased in BL+ST+BL group fed with B. longum HY8--1 before and after challenge(p<0.05), while the fecal shedding s of S. typhimurium DT104 in BL+ST and St groups remained more than 106cfu. the protective effect of the B. longum HY8001 against E. coli O157:H7 was significantly high only in BL+E+BL group fed with b. longum Hy8001 before and after E. coli O157:H7 challenge from the result of fecal E. coli O157:H7 isolation rate, mortality rate, and intestinal contents culture to detect E. coli O157:H7. the mortality rate of the BL+e and E groups. The cytopathic effect (CPE) of the Vero cytotoxin (Shiga like toxin I & II) in Vero cell was neutralized in B. longum HY8001 culture supernatant added wells which indicate the presence of soluble Vero cytotxin neutralizing substance(s) in B. longum HY8001 culture suprnatant.

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무기체계 업체주관 연구개발 사업의 개발시험평가 개선방안 고찰 (A Study on the Improvement Method of DT&E for Company Organized Weapon Systems Research and Development)

  • 김성경;김찬동;허장욱
    • 한국군사과학기술학회지
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    • 제18권6호
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    • pp.721-727
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    • 2015
  • The improvement of the reliability of weapon systems and the reduction of the total life-cycle cost based on the improving of the DT&E system for Company Organized weapon systems research and development are urgently required. The major advanced countries operate test and evaluation centers for military (U.S.), manage a large scale organization of IPT personnel (England) or conduct management of DT&E through a third party organization (France). Based on a survey of experts, an improvement of the DT&E policy in terms of reliability and objectiveness is needed, and management through a third party national defense agency and civilian agency such as the Surion development case is required. In addition, although it appears that efficiency improves when management of DT&E is performed by national defence agencies rather than civilian agencies, it is necessary to proceed by selecting a civilian agency based on competition in the case that it is difficult to select a national defence agency.

데이터 기술: 지식창조를 위한 새로운 융합과학기술 (Data Technology: New Interdisciplinary Science & Technology)

  • 박성현
    • 품질경영학회지
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    • 제38권3호
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    • pp.294-312
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    • 2010
  • Data Technology (DT) is a new technology which deals with data collection, data analysis, information generation from data, knowledge generation from modelling and future prediction. DT is a newly emerged interdisciplinary science & technology in this 21st century knowledge society. Even though the main body of DT is applied statistics, it also contains management information system (MIS), quality management, process system analysis and so on. Therefore, it is an interdisciplinary science and technology of statistics, management science, industrial engineering, computer science and social science. In this paper, first of all, the definition of DT is given, and then the effects and the basic properties of DT, the differences between IT and DT, the 6 step process for DT application, and a DT example are provided. Finally, the relationship among DT, e-Statistics and Data Mining is explained, and the direction of DT development is proposed.

혼합물실험설계법에 의한 라면 밀가루 혼합비의 최적화 (Optimization of Ramen Flour Formulation by Mixture Experimental Design)

  • 박해룡;이승주
    • 산업식품공학
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    • 제15권4호
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    • pp.297-304
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    • 2011
  • 혼합물실험계획법(mixture experimental design)을 적용하여 라면 밀가루 혼합비를 최적화하였다. 밀가루 혼합비를 최적화하기 위하여 전체 기호도(overall palatability)의 최대화, 반죽 레올로지 특성의 특정 범위 유지를 최적화의 목적으로 설정하였다. 라면은 가장 보편적인 미국산 밀가루 중 강력분인 DNS, 중력분인 HRW, 박력분인 SW를 simplex-lattice 방식에 의해 혼합비를 달리하여 제조하였다. 각 시료는 Rapid Visco Analyser(RVA), 파리노그래프, 익스텐소그래프를 이용하여 반죽의 레올로지 특성치를 측정하였으며, 조리된 라면의 전체 기호도를 관능 검사 하였다. 정준상관분석(canonical correlation analysis)를 통하여 RVA의 최고점도(PV), 파리노그래프의 반죽형성시간(DT), 익스텐소그래프의 R/E 45 min을 주요 반죽 레올로지 특성치로 선발하였다. 최적화 목적으로 전체 기호도의 최대화와 최고점도(PV)(최대화), 반죽형성시간(DT)(최소화) 및 R/E45 min(최대화)를 지정하였다. 그 결과 최적화된 밀가루 혼합비는 DNS 33.3%, HRW 33.3% 및 SW 33.3% 이였으며, 이때 전체 기호도는 5.825, 최고점도(PV)는 587.9 cP, 반죽형성시간(DT)은 3.1 min, R/E 45 min는 2.339 BU/mm로 나타났다.

함정사업 시험평가의 효율적 수행방안에 관한 연구 (A Study on Efficient Test & Evaluation Methods in Naval Ship Acquisitions)

  • 김재용;최원석;홍석윤;정현균;송지훈;임우석;권현웅
    • 한국군사과학기술학회지
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    • 제19권6호
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    • pp.703-711
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    • 2016
  • The purposes of this study is to identify the problems arising from current Test & Evaluation process of the naval ship acquisition program and to suggest methods to increase the acquisition efficiency. Considering that the present rule of developmental test &evaluation(DT&E) and operational test & evaluation(OT&E) has caused an inefficiency effect on the acquisition procedures due to the limited practices on it, the DT&E and OT&E procedures through test & evaluation master plan(TEMP) is proposed based on the selective practices of the defense instruction articles. Also, considering characteristics of naval ship acquisitions, efficient procedure systems are derived through case analysis results by comparing each performances of the system. The suggested methods are able to meet the requirements of the changed acquisition environments and also increase efficiency of acquisition systems by adoption of DT&E and OT&E combined test scheme.

Tele-Manipulation of ROBHAZ-DT2 for Hazard Environment Applications

  • Ryu, Dong-Seok;Lee, Jong-Wha;Yoon, Seong-Sik;Kang, Sung-Chul;Song, Jae-Bok;Kim, Mun-Sang
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.2051-2056
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    • 2003
  • In this paper, a tele-manipulation in explosive ordnance disposal(EOD) applications is discussed. The ROBHAZ-DT2 is developed as a teleoperated mobile manipulator for EOD. In general, it has been thought that the robot must have appropriate functions and accuracy enough to handle the complicated and dangerous mission. However, the research on the ROBHAZ-DT2 revealed that the teleoperation causes more restrictions and difficulties in EOD mission. Thus to solve the problem, a novel user interface for the ROBHAZ-DT2 is developed, in which the operator can interact with various human senses (i.e. visual, auditory and haptic sense). It enables an operator to control the ROBHAZ-DT2 simply and intuitively. A tele-manipulation control scheme for the ROBHAZ-DT2 is also proposed including compliance control via force feedback. It makes the robot adapt itself to circumstances, while the robot faithfully follows a command of the operator. This paper deals with a detailed description on the user interface and the tele-manipulation control for the ROBHAZ-DT2. An EOD demonstration is conducted to verify the validity of the proposed interface and the control scheme.

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ON THE CAUCHY PROBLEM FOR SOME ABSTRACT NONLINEAR DIFFERENTIAL EQUATIONS

  • Hamza A.S. Abujabal;Mahmoud M. El-Boral
    • Journal of applied mathematics & informatics
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    • 제3권2호
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    • pp.279-290
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    • 1996
  • In the present paper we study the Cauchy problem in a Banach space E for an abstract nonlinear differential equation of form $$\frac{d^2u}{dt^2}=-A{\frac{du}{dt}}+B(t)u+f(t, W)$$ where W=($A_1$(t)u, A_2(t)u)..., A_{\nu}(t)u), A_{i}(t),\;i=1,2,...{\nu}$,(B(t), t{\in}I$=[0, b]) are families of closed operators defined on dense sets in E into E, f is a given abstract nonlinear function on $I{\times}E^{\nu}$ into E and -A is a closed linar operator defined on dense set in e into E which generates a semi-group. Further the existence and uniqueness of the solution of the considered Cauchy problem is studied for a wide class of the families ($A_{i}$(t), i =1.2...${\nu}$), (B(t), $t{\in}I$) An application and some properties are also given for the theory of partial diferential equations.

Implementation of Electrochemical Methods for Metrology and Analysis of Nano Electronic Structures of Deep Trench DRAM

  • Zeru, Tadios Tesfu;Schroth, Stephan;Kuecher, Peter
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제12권2호
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    • pp.219-229
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    • 2012
  • In the course of feasibility study the necessity of implementing electrochemical methods as an inline metrology technique to characterize semiconductor nano structures for a Deep Trench Dynamic Random Access Memory (DT-DRAM) (e.g. ultra shallow junctions USJ) was discussed. Hereby, the state of the art semiconductor technology on the advantages and disadvantages of the most recently used analytical techniques for characterization of nano electronic devices are mentioned. Various electrochemical methods, their measure relationship and correlations to physical quantities are explained. The most important issue of this paper is to prove the novel usefulness of the electrochemical micro cell in the semiconductor industry.

획득환경변화(獲得環境變化)에 따른 효율적(效率的)인 무기체계(武器體系) 시험평가(試驗評價) 방법(方案) (Effective Test & Evaluation Method of Weapon Systems in the Change of Acquisition Environment)

  • 양병희;김흥빈
    • 한국국방경영분석학회지
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    • 제31권1호
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    • pp.93-106
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    • 2005
  • The complexity of modern weapon systems using the IT(intelligence technology) demands that rapid and effective transition from force requirements to deployment and fielding. Thus this paper deals with the DT&E(developmental test & evaluation), OT&E(operational test & evaluation) and SBT(simulation based test) procedure using the case study in the test & evaluation of weapon systems. This study is aimed to produce the effective test & evaluation method of weapon systems in the change of acquisition environment.

VOLUMES OF GEODESIC BALLS IN HEISENBERG GROUPS ℍ5

  • Kim, Hyeyeon
    • 충청수학회지
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    • 제32권3호
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    • pp.349-363
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    • 2019
  • Let ${\mathbb{H}}^5$ be the 5-dimensional Heisenberg group equipped with a left-invariant metric. In this paper we calculate the volumes of geodesic balls in ${\mathbb{H}}^5$. Let $B_e(R)$ be the geodesic ball with center e (the identity of ${\mathbb{H}}^5$) and radius R in ${\mathbb{H}}^5$. Then, the volume of $B_e(R)$ is given by $${\hfill{12}}Vol(B_e(R))\\{={\frac{4{\pi}^2}{6!}}{\left(p_1(R)+p_4(R){\sin}\;R+p_5(R){\cos}\;R+p_6(R){\displaystyle\smashmargin{2}{\int\nolimits_0}^R}{\frac{{\sin}\;t}{t}}dt\right.}\\{\left.{\hfill{65}}{+q_4(R){\sin}(2R)+q_5(R){\cos}(2R)+q_6(R){\displaystyle\smashmargin{2}{\int\nolimits_0}^{2R}}{\frac{{\sin}\;t}{t}}dt}\right)}$$ where $p_n$ and $q_n$ are polynomials with degree n.