• 전자공학회논문지B
• /
• 제33B권2호
• /
• pp.103-110
• /
• 1996

In this paper, we propose a unified systolic array for the computation of the 2D discrete cosine transform/discrete sine transform/discrete hartley transform (DCT/DST/DHT). The unified systeolic array for the 2D DCT/DST/DHT is a generalization of the unified systolic array for the 1D DCT/DST/DHT. In order to calculate the 2D transform, we compute 1D transforms along the row, transpose them, and obtain 1D transforms along the column. When we compare the proposed systolic array with the conventional method, our architecture exhibits a lot of advantages in terms of latency, throughput, and the number of PE's. The simulation results using very high speed integrated circuit hardware description language (VHDL), international standard language for hardware description, show the functional validity of the proposed architecture.

• 한국통신학회논문지
• /
• 제31권9B호
• /
• pp.792-802
• /
• 2006

In this paper, we propose an energy-efficient proactive data dissemination protocol with relatively low delay to cope well with highly mobile sink environments in sensor networks. In order for a dissemination tree to continuously pursue a dynamic sink, we exploit two novel algorithms: forward sink advertisement and distributed fast recovery. In our protocol, the tree is shared with the other slave sinks so that we call it Dynamic Shared Tree (DST) protocol. DST can conserve considerable amount of energy despite maintaining robust connection from all sources to sinks, since tree maintenance of DST is accomplished by just distributed local exchanges. In addition, since the DST is a kindof sink-oriented tree, each source on the DST disseminates data with lower delay along the tree and it also facilitates in-network processing. Through simulations, it is shown that the presented DST is considerably energy-efficient, robust protocol with low delay compared to Directed Diffusion, TTDD, and SEAD, in highly mobile sink environment.

• 설비공학논문집
• /
• 제26권9호
• /
• pp.416-423
• /
• 2014

To verify different boundary conditions on the borehole wall, which are commonly used for generating g-function, the well-known TRNSYS simulation model, DST (Duct STorage), is employed. By letting the fluid circulation determine the borehole wall conditions, a DST-based g-function is induced with numerical processes proposed in this work. A new TRNSYS module is also developed to accommodate g-function data and predict dynamic outlet fluid temperatures. Results showed that the modified g-function, which is different from Eskilson's original g-function, is closer to the DST-based g-function. This implies that the uniform heat transfer rates over the height can be used for good approximation. In fact, simulations with the modified g-function showed similar results as the DST model, while Eskilson g-function case deviated from the DST model as time progressed.

• 방송공학회논문지
• /
• 제22권3호
• /
• pp.321-326
• /
• 2017

HEVC 표준은 정수 화소로 표현된 신호에 DCT-II를 기반으로 하는 보간 필터를 사용하여 부화소 신호를 생성한다. 이러한 방법으로 생성된 신호는 움직임 보상 및 예측의 성능 향상을 가져온다. HEVC 표준은 부화소를 생성하기 위해서 길이가 다른 각각의 DCT 보간 필터를 사용하고 있다. 1/2-화소를 생성할 땐, 필터의 길이가 8인 DCT 기반 보간 필터를 사용하며, 1/4-화소와 3/4-화소의 경우에는 필터의 길이가 7인 DCT 기반 보간 필터를 사용한다. 본 논문에서는 DST-VII을 기반으로 하는 보간 필터를 제안하여, 움직임 보상 및 예측의 성능 향상을 가져온다. 본 논문에서 제안하는 방법은 HEVC 표준보다 BD-rate가 Random Access와 Low Delay B configurations에서 각각 0.45%와 0.5%의 성능 향상을 가져온다.

• 대한한방내과학회지
• /
• 제32권4호
• /
• pp.565-583
• /
• 2011

Objectives : This study investigated the biochemical mechanisms of anti-proliferative and pro-apoptotic effects of the water extract of Dan-Seon-Tang (DST) in human leukemia U937 cells. Methods : U937 cells were exposed to DST and growth inhibition was measured by MTT assay. Results : Exposure of U937 cells to DST resulted in the growth inhibition in a concentration-dependent manner. This inhibitory effect was associated with morphological changes and apoptotic cell death such as formation of apoptotic bodies, increased populations of apoptotic-sub G1 phase and induction of DNA fragmentation. The induction of apoptotic cell death in U937 cells by DST was associated with up-regulation of death receptor 4 (DR4) and down-regulation of Bid, surviving and cellular inhibition of apoptosis protein-2 (cIAP-2) expression. DST treatment also induced the proteolytic activation of caspase-3, caspase-8 and caspase-9, and a concomitant degradation of caspase-3 substrate proteins such as poly (ADP-ribose) polymerase (PARP), phospholipase (PLC)-${\gamma}1$, ${\beta}$-catenin and DNA fragmentation factor 45/inhibotor of caspase activated DNAse (DFF45/ICAD). Furthermore, apoptotic cell death by DST was significantly inhibited by caspase-3 specific inhibitor z-DEVD-fmk, demonstrating the important role of caspase-3. Conclusions : These findings suggest that herb prescription DST may be a potential chemotherapeutic agent for the control of human leukemia U937 cells; further study is needed to identify the active compounds.

• Journal of Astronomy and Space Sciences
• /
• 제26권3호
• /
• pp.329-344
• /
• 2009

일광절약시간제는 하절기에 낮 시간을 효율적으로 활용하기 위한 것이다. 한국은 해방이후부터 1988년까지 12번의 일광절약시간제를 시행하였다. 지난 20여년간 이 제도가 실시되지 않았으나, 최근에 일광절약시간제의 시행에 관한 문제가 다시 제기되고 있다. 이 논문에서는 세계 여러 국가의 일광절약시간제 시행경향, 한국의 일광절약시간제 실시의 역사를 살펴보고, 일출 몰시각 변화에 따른 낮의 길이 변화를 계산해 한국에 적합한 일광절약시간제 시행시기를 연구하였다. 한국은 동경 $135^{\circ}$ 표준자오선을 사용하고 있는데, 일출시각과 표준자오선의 지역적 치우침을 고려해 계산한 결과, 5월 두번째 일요일이나 4월 두번째 일요일이 적절한 일광절약시간제의 시작시기임을 알아내었다. 또한 일광절약시간제를 시행할 경우 발생하는 한국표준시에 대한 시간마찰과 이에 파생되는 문제들을 논하였다.

• 대한한방부인과학회지
• /
• 제19권2호
• /
• pp.77-91
• /
• 2006

Purpose : To address the ability of Dohaekseungkitang (DST: a commonly used herb formulation in Korea, Japan and China to have anti-cancer effect on cervical carcinoma), we investigated the effects of DST on programmed cell death (apoptosis) in HeLa human cervical carcinoma cells. Methods : We cultured HeLa cell which is human metrocarcinoma cell in D-MEM included 10% fetal bovine serum(Hyclone Laboratories) below $37^{\circ}C$, 5% CO2. Then we observed apoptosis of log phage cell which is changed cultivation liquid 24 Hours periodically. Results : After the treatment of DST for 48 hours, apoptosis occurred in a dose-dependent manner. In this study, we have shown that DST induces calpain and the associated caspase-8 and -9 activations. Apoptosis was prevented by pre-incubation of the cells with the calcium cHeLator-BAPTA-AM, calcium channel blocker-Nif edipine or Ryonidine agonist-Ryonidine peptide, implicating calcium in the apoptotic process. Ubiquitous calpains (mu- and m-calpain) have been repeatedly implicated in apoptosis, especially in calcium-related apoptosis. However this study showed 1hat either calpain inhibitor-calpastin or caspase-3 inhibitor-DEVD- did not blocked the herb formulation-induced apoptosis in HeLa human cervical carcinoma cells. D ST initiates a cell death pathway that is partially dependent of caspases. DST-induced apoptosis requires caspase-independent mechanism. Conclusion : We conclude that DST-induced calpain activation triggers the intrinsic apoptotic pathway in which caspase-independent mechanism is also involved.

• Clinical and Experimental Pediatrics
• /
• 제60권10호
• /
• pp.312-319
• /
• 2017

Purpose: To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment. Methods: This study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive tests conducted in 209 of 1,403 patients, of whom 758 underwent the K-DST at the Korea University Guro Hospital between January 2015 and December 2016 and 645 were referred from local clinics between January 2015 and June 2016. Results: Based on the K-DST results, the male children significantly more frequently required further or follow-up examination than the female children in most test sections, except for gross motor. The male children had notably lower mean scores than the female children. The PRES/SELSI results showed that when more further or follow-up evaluations were required in the K-DST communication section, significantly more problems in language delay or disorder emerged. When further or follow-up evaluation was required in the cognitive section in the CARS/M-CHAT, the possibility of autism increased significantly. A child tended to score low in the CARS test and show autism when further or follow-up evaluation was recommended in the K-DST. Conclusion: This study demonstrated the usefulness of the K-DST as a screening test early in the development of infants and children in Korea. Data of normal control groups should be examined to determine the accuracy of this investigation.

• Clinical and Experimental Pediatrics
• /
• 제62권5호
• /
• pp.187-192
• /
• 2019

Purpose: The importance of the neurodevelopmental outcomes of very-low-birth-weight (VLBW) infants has been emphasized as their mortality rate has markedly improved. This study aimed to assess the validity of the Korean Developmental Screening Test (K-DST), a developmental screening tool approved by the Korean Society of Pediatrics, for the timely diagnosis of neurodevelopmental delay in VLBW infants. Methods: Subjects included VLBW infants enrolled in the Korean Neonatal Network database between January 2012 and December 2014. The collected data were analyzed for sensitivity, specificity, positive predictive value, and negative predictive value (NPV) in the K-DST compared to those in the Bayley Scales of Infant Development-II for VLBW infants. Results: A total of 173 patients were enrolled. Their mean gestational age and mean birth weight were $27.5{\pm}2.8weeks$ and $980.5{\pm}272.1g$, respectively. The frequency of failed psychomotor developmental index (PDI) <85 was similar to that in at least one domain of K-DST <1 standard deviation. Failure in more than one K-DST domain compared with a mental developmental index (MDI) <85 showed a sensitivity and NPV of 73.2% and 75.0%, respectively. Failure in more than one K-DST domain compared with PDI <85 showed a sensitivity and NPV of 60.3% and 71.6%, respectively. Each K-DST domain had a stronger correlation with predicting a failing MDI <85 than a failing PDI <85 (P<0.05). Conclusion: K-DST could be a useful screening tool for predicting mental developmental delay in VLBW infants and referring them for neurodevelopmental assessments.

• 한국철도학회논문집
• /
• 제15권5호
• /
• pp.517-523
• /
• 2012

이단적재화물열차는 미국 및 캐나다를 중심으로 활성화되어 있다. 이러한 이단적재열차의 장점으로는 화차의 길이 및 열차의 길이를 늘이지 않고도 대량수송이 가능한 시스템을 구축하는 것이므로 철도물류사업의 경쟁력을 대폭 강화하는 혁신적인 열차라고 할 수 있다. 국내의 경우도 물류수송량이 증가하고 있으며 친환경녹색교통수단인 철도물동량을 증대시키기 위해선 화물열차를 장대화하는 것 외에도 이단적재방식을 추가로 도입하는 것이 대량수송 확보 측면 및 효율성 측면에서 보다 유리할 것이다. 본 연구에서는 경부선에 이단적재방식을 도입하기 위한 시스템 구축비용이 많이 소요됨에 따라 대안으로 기존선 개량사업을 추진 중에 있어 이단적재시스템 구축 비용이 비교적 적게 소요되는 경전선을 대상으로 이단적재열차 도입을 위해 운임탄력성 연구를 수행하였으며, 철도운임과 연동된 추가적인 철도물동량 증대가능성을 조사한 바, 이단적재열차가 경전선에 도입될 경우 대량수송에 의한 단위수송원가 절감으로 인해 철도운송경쟁력이 향상되고, 운송업체에게 직접 운임 인하를 추가로 적용할 수 있을 것으로 예상되어 관련업체를 대상으로 조사한 결과 도로운송비용 대비 3만원(현재 운임의 약 37.7%할인 수준) 저렴하게 수송이 가능하다면 약 63%까지 철도로의 수송전환이 이루어질 것으로 분석되었다.