• 산업공학
• /
• 제14권4호
• /
• pp.374-384
• /
• 2001

The objective of this paper is to design the dynamic route guidance system(DRGS) and develop a genetic algorithm(GA) for finding the multiple shortest paths in real traffic network. The proposed GA finds a collection of paths between source and destination considering turn-restrictions, U-turn, and P-turn that are genetically evolved until an acceptable solution is reached. This paper also shows the procedure to find the multiple shortest paths in traffic network of Seoul.

• 동의생리병리학회지
• /
• 제29권5호
• /
• pp.416-421
• /
• 2015

This study was performed to comparative investigate the distribution of primary sensory and motor neurons associated with Daereung(PC7) acupoints by using neural tracing technique. A total 16 SD rats were used in the present study. After anesthesia, the rats received microinjection of 6 ㎕ of cholera toxin B subunit(CTB) into the corresponding sites of the acupoints Daereung(PC7), in the human body for observing the distribution of the related primary sensory neurons in dorsal root ganglia(DRGs) and motor neurons in the spinal cord(C3∼T4) and sympathetic ganglia. Three days after the microinjection, the rats were anesthetized and transcardially perfused saline and 4% paraformaldehyde, followed by routine section of the DRGs, sympathetic chain ganglia(SCGs) and spinal cord. Labeled neurons and nerve fibers were detected by immunohistochemical method and observed by light microscope equipped with a digital camera. The labeled neurons were recorded and counted. From this research, the distribution of primary sensory and motor neurons associated with Daereung(PC7) acupoints were concluded as follows. Muscle meridian related Daereung(PC7) controlled by spinal segments of C5∼T1, C6∼T4, respectively.

• 지식경영연구
• /
• 제16권1호
• /
• pp.209-224
• /
• 2015

Previous studies provided that limiting the number of services provided in hospital had influences in decreasing cost in delivering medical services. Hospitals could have positive effects on their profit by concentrating small number of services which they have comparative advantages. This study purposed to analyze the relationship between the concentration status of hospitals and medical charge for inpatients. National Inpatient sample data provided by the Health Insurance Review and Assessment Service (HIRA) for three years, 2009 to 2011 was used to compute the three concentration indices (Information Theory Index (ITI), Internal Herfindahl Index (IHI), and number of distinct Diagnosis-Related Groups (DRGs) treated) and total medical charge per inpatient case in each year. It was also used to select the control variables such as bed size, number of doctors per 100 beds, and locations. The ordinary least square regression models were developed and tested for hospital and general hospitals separately. The results showed that the total medical charge per inpatient case was significantly differed depending on the concentration indices, and there were positive relationships in ITI and IHI. The number of distinct DRGs had different directions in regression coefficients depending on the locations and hospital types. Hospitals had larger absolute standardized regression coefficients compare to those of general hospitals. However, their effects could be varied by the hospital types, number of doctors, and locations. It seems that hospitals have more influences on medical charges by concentrating their services than general hospitals. Study results provide knowledges to hospital administrators that concentration strategy can positive influences on the performance of small size hospitals.

• 보건행정학회지
• /
• 제8권1호
• /
• pp.1-14
• /
• 1998

Analysis of practice variations has been one of important issues in trying to contain costs as well as to manage quality in health care. This study was conducted to provide statistical model for analysing variations in inpatient costs by type of hospitals. Four K-DRGs including Cesarean section, appendectomy, cataract extraction, and pediatric pneumonia with CC class 0 were selected, and means and dispersions of inpatient procedure and operation costs were simultaneously compared between type of hospitals. The results indicated that joint modelling of means and dispersions by gamma distribution was a very useful analytic tool for identifying factors which might have relationship with variations in inpatient costs. This model can be expanded to test the significance of several independent variables in analysing cost variations. In surgical conditions, means and unit variations of procedure and operation costs showed consistent pattern which was tertiarty hospital, general hospital, and hospital in descending order. Different findings were identified in pediatric pneumonia, from which mean and unit variation of procedure and operation cost was the highest in general hospital. The practical implication of this difference could not be drawn from this study. It will be done by further sophisticated researches. In order to develop health policy for cost containment and quality management in Korea, it is essential to find out manageable factors affecting variations in practice patterns which include characteristics of population, providers, regions, and so on. The statistical model presented in this study will give health services researchers useful insights for future investigations in analysing cost variations.

• Journal of Ginseng Research
• /
• 제42권4호
• /
• pp.470-475
• /
• 2018

Background: It was previously found that Korean Red Ginseng water extract (KRGE) inhibits the histamine-induced itch signaling pathway in peripheral sensory neurons. Thus, in the present study, we investigated whether KRGE inhibited another distinctive itch pathway induced by chloroquine (CQ); a representative histamine-independent pathway mediated by MrgprA3 and TRPA1. Methods: Intracellular calcium changes were measured by the calcium imaging technique in the HEK293T cells transfected with both MrgprA3 and TRPA1 ("MrgprA3/TRPA1"), and in primary culture of mouse dorsal root ganglia (DRGs). Mouse scratching behavior tests were performed to verify proposed antipruritic effects of KRGE and ginsenoside Rg3. Results: CQ-induced $Ca^{2+}$ influx was strongly inhibited by KRGE ($10{\mu}g/mL$) in MrgprA3/TRPA1, and notably ginsenoside Rg3 dose-dependently suppressed CQ-induced $Ca^{2+}$ influx in MrgprA3/TRPA1. Moreover, both KRGE ($10{\mu}g/mL$) and Rg3 ($100{\mu}M$) suppressed CQ-induced $Ca^{2+}$ influx in primary culture of mouse DRGs, indicating that the inhibitory effect of KRGE was functional in peripheral sensory neurons. In vivo tests revealed that not only KRGE (100 mg) suppressed CQ-induced scratching in mice [bouts of scratching: $274.0{\pm}51.47$ (control) vs. $104.7{\pm}17.39$ (KRGE)], but also Rg3 (1.5 mg) oral administration significantly reduced CQ-induced scratching as well [bouts of scratching: $216.8{\pm}33.73$ (control) vs.$115.7{\pm}20.94$ (Rg3)]. Conclusion: The present study verified that KRGE and Rg3 have a strong antipruritic effect against CQ-induced itch. Thus, KRGE is as a promising antipruritic agent that blocks both histamine-dependent and -independent itch at peripheral sensory neuronal levels.

• 한국병원경영학회지
• /
• 제7권1호
• /
• pp.105-120
• /
• 2002

In the United States, the prospective payment system(PPS), under which diagnosis related groups (DRGs) are used to reimburse hospitals for the care of Medicare patients since 1983, Study results showed that the PPS is having a major impact on the quantity of services especially of hospital length of stay. The PPS has increased the likelihood that a patient will be discharged home in an unstable condition and the use of nursing homes or long term care facilities increased. Still, it is insufficient to conclude that the PPS has decreased the Medicare total expenditure, but relatively sufficient to conclude that the quality of care hasn't changed. The maintenance of the quality resulted from the systemic "check-and-balance" composed of three factors; (1) The doctors are reimbursed based on the fee-for-service system, (2) hospitals contact with doctors under the attending system, and (3) there are some public hospitals. In Korea, the reimbursement for hospitals and doctors are not divided, the hospitals have doctors as employees, and 90% of hospitals are private. These differences may weaken the "check-and-balance" existing in the U.S. system. And there are few long term care facilities and the diagnostic coding system using in pilot test are not suitable for Korean situation. In conclusion, for successful implementation of the DRG payment system in Korea, the government should establish the "check-and-balance" system in the health sector to make sure the quality of care before the implementation.

• 대한교통학회지
• /
• 제26권5호
• /
• pp.185-194
• /
• 2008

본 논문에서는 기본적으로 라우팅(routing) 메커니즘을 이용하는 개미 알고리즘(ant algorithm)을 이용하여 실시간으로 변화하는 교통 상황과 U턴, P턴 및 회전제약(좌회전 및 U턴 금지)을 고려하여 다수의 최적경로를 제한된 시간내에 탐색제시 할 수 있는 경로 유도 방법을 제시하고자 한다. 이 방법은 기존 최적경로알고리즘과 비교하여 회전 제약 상황을 쉽고 빠르게 고려할 수 있는 장점이 있다.

• 보건의료산업학회지
• /
• 제8권4호
• /
• pp.13-24
• /
• 2014

This study analyzes the effects of hospital caseload on medical charges and length of stay for inpatients. Hospital caseload, representing the level of concentration of patients, was measured with the Internal Herfindal Index for three diagnosis related group (DRG) codes (appendectomy, operations on anus, and operations on uterus and adnexa). Ordinary least squares regression was used for analysis. Results showed that medical charges per inpatient and average length of stay significantly differed with respect to hospital concentration indices, and that hospital caseload was inversely related to operational performance for appendectomy and operations on uterus and adnexa. The significant negative relationship between concentration index and length of stay may decrease the total medical charges. The results imply that the expansion of the DRG payment system to hospitals will have a negative influence on their gross sales.

• 대한교통학회지
• /
• 제13권1호
• /
• pp.95-110
• /
• 1995

n this research neural -based model was developed to forecast link travel times , And it is also compared wiht other time series forecasting models such as Box-Jenkins model, Kalman filter model. These models are validated to evaluate the accuracy of models with real time series data gathered by the license plate method. Neural network's convergency and generalization were investigated by modifying learning rate, momentum term and the number of hidden layer units. Through this experiment, the optimum configuration of the nerual network architecture was determined. Optimumlearining rate, momentum term and the number of hidden layer units hsow 0.3, 0.5, 13 respectively. It may be applied to DRGS(dynamic route guidance system) with a minor modification. The methods are suggested at the condlusion of this paper, And there is no doubt that this neural -based model can be applied to many other itme series forecating problem such as populationforecasting vehicel volume forecasting et .

• 한국정보과학회논문지:데이타베이스
• /
• 제30권3호
• /
• pp.296-309
• /
• 2003

모바일 컴퓨팅의 상업적인 응용분야로서, 지능형 교통정보시스템(ITS: Intelligent Transport Systems)의 한 분야인 첨단 여행자 정보시스템(ATIS: Advanced Traveler Information Systems )이 있다. ATIS에서 가장 중요한 모바일 컴퓨팅 태스크는 현재 위치에서 목적지까지의 최단 경로를 계산하는 일이다. 본 논문에서는 ATIS의 동적 경로 안내 시스템(DRGS: Dynamic Route Guidance System)에서 발생하는 최단 경로 재 계산 문제에 대해서 연구하였다. 이 문제는 동적인 교통상태에 따라 디지털 로드 맵 상의 간선 비용이 빈번하게 갱신되기 때문에 발생한다. 기존의 방법들은 처음부터 최단 경로를 재 계산하거나, 또는 단지 비용의 변화가 일어난 간선 상에 있는 양 꼰 노드 사이에 대해서만 최단 경로를 재 계산할 뿐이다. 이러한 방법은 앞서 계산된 최단 경로에 대한 정보를 이용하지 않는다는 점에서 모두 비효율적이다. 이에, 본 논문에서는 효율적인 동적 윈도우 기반의 근접 최단 경로 재 계산 방법(A Dynamic Window-Based Approximate Shortest Path Re-Computation Method)을 제안한다. 이 방법은 앞서 계산된 최단 경로의 정보를 이용하여 최적의 최단 경로에 상당히 근접한 경로를 매우 빠른 시간 안에 계산해 낸다. 우리는 제안한 방법을 이론적으로 분석한 다음 이를 격자 그래프 및 실제 디지털 로드맵 상에 구현하여 철저한 실험적인 성능 분석을 하였다.