• Toxicological Research
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• 제17권
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• pp.167-171
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• 2001

The introduction of genetically modified crops has raised concerns regarding safety issues over the insertion of foreign genes into plant genomes using recombinant DNA technology. Since 1991 in Japan, 29 foods and 6 food additives have been evaluated, based on the "Guideline for Safety Assessment", before these foods were marketed. The MHW, however, decided that safety assessment of such foods and food additives should be legally imposed. because soon such foods and food additives are expected to circulate globally and a new system for assessing safety of such foods and food additives at a pre-market stage is necessary, in order to avoid the distribution of any genetically modified foods that have had no safety assessment. The MHW published relevant announcements to amend existing regulations on 1 May 2000. "Standards for safety assessment of seed plant" is established based on a concept of substantial equivalence, and applicable to the products which are regarded as equivalent to the existing products used as foods and food additives. The characterization of the food products entails consideration of the molecular characterization. phenotypic and compositional characteristics, key nutrients and toxicants, and toxicity and allergenicity of the introduced proteins, and if there are indications of unintended effects of the modification, whether further safety testing (animal studies etc.) is needed should be considered. Safety and wholesomeness studies with whole foods should be care fully designed in order to avoid nutritional imbalances causing artifacts and uninterpretable results as was the case of Dr. Pusztaiis report. A case study of genetically modified soybeans (glyphosate-tolerant soybeans) on the immune system of rats and mice is shown. Chemical compositions were also compared with those of the non-GM soybeans. The studies failed to detect any differences in immuno-toxic activity.muno-toxic activity.

• 한국항만경제학회지
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• 제29권4호
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• pp.175-199
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• 2013

본 연구는 부산신항 컨테이너터미널 운영사가 수립하여 실행한 터미널운영전략의 효과를 전략실행프로세스(XPP)모델에 의거하여 진단하고 전략실행력을 제고할 수 있는 방안을 제시하고자 하였다. 연구결과에 의하면, 부산항 컨테이너터미널 운영사의 전략실행프로세스 요인 모두 미흡한 수준으로 전략의 수립부터, 전략의 구체화, 조직과 정렬 운영계획과의 연계 그리고 전략의 모니터링과 업그레이드 전체과정을 합리적이고 유기적으로 실시간 실행할 수 있는 맞춤형 XPP시스템 구축이 매우 시급한 것으로 사료된다. 또한 북항은 부산신항에 비하여 컨테이너 전용터미널로서 경쟁력을 점차 상실되고 있어 북항재개발을 서둘러 북항의 용도변경을 하여야만 부산항 전체의 경쟁력을 확보할 수 있는 것으로 판단된다. 경영자의 리더쉽요인은 중요한 요인이지만 미흡한 수준으로서 CEO의 리더쉽을 발휘할 수 있는 여건 마련과 역량 강화가 시급하다. 터미널 경쟁력에 중요한 인적자원 역량 강화를 위해서는 전략수립을 구체화하는 과정으로 BSC Map의 체계적인 작성과 실행 가능한 전략적 과제의 도출 및 이들의 전체 조직에의 전파와 구체적인 실행계획 및 예산이 뒷받침 되어야 하며, 이를 위한 전략관리 기획본부나 팀같은 조직구축이 시급한 것으로 사료된다.

• 한국임상수의학회지
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• 제16권2호
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• pp.248-252
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• 1999

본 연구는 진도개, 풍산개 및 잡종견의 혈액학 및 혈액화학치의 차이를 비교하고자 본 실험을 수행하였다. 총 80두가 본 조사에 이용되었으며 경기도지방, 제주도, 서울 및 전남지방을 대상으로 실시하였다. 각각 진도개 30두, 풍산개 20두 및 잡종견 30두로 구성되었으며 성비는 각 군간에 차이가 없었다(진도개: 수캐=16, 암캐=14, 풍산개 : 수캐=9, 암캐=11, 잡종견: 수캐=15, 암캐=15). 연령은 진도개, 풍산개 및 잡종견 각각 1.3$\pm$0.9(년), 1.3$\pm$1.0(년), 1.3$\pm$ 1.6(년)이었다. 체종분포는 진도개, 풍산개 및 잡종견은 각각 9.0$\pm$4.5 kg, 9.8$\pm$4.0 kg, 8.4$\pm$4.7 kg이었다. 잡종견의 백혈구와 호중구수가 다른 두품종에 비해 유의성있게 높았다 (p<0.05). 풍산개의 림프구와 호산구수는 진도개와 잡종견의 수보다 높았다(p＜0.05). 하지만 풍산개의 단핵구 수는 진도개와 잡종견보다 유의성있게 낮았다(p<0.05). 진도개의 콜레스테롤과 무기인 수준은 풍산개와 잡종개의 수준보다 낮았다. 잡종견의 중성지방(triglyceride)의 수준은 진도개와 풍산개의 수준보다 낮았다. 잡종견의 나트륨 농도는 진도개와 풍산개의 수준보다 낮았으며 진도견의 칼륨농도는 풍산개와 잡종견의 농도와 비교하여 높았다. 바베시아 검사에서 모든 품종에서 음성이었으며 심장사상충 검사결과 양성율은 잡종견, 진도견과 풍산견 각각 20%, 10%, 10%이었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권10호
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• pp.4325-4329
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• 2014

Background: The expatriate population in Qatar largely comprises workers from the Indian subcontinent which has a very high rate of oral malignancy. Social and cultural habits and as well premalignant risk factors in this population remain prevalent even after migration. Materials and Methods: This cross sectional study assessed the prevalence of risk factors and occurrence of oral precancerous lesions in a low income group expatriate community from the Indian subcontinent residing in Qatar. Results: Among the 3,946 participants screened for oral premalignant lesions 24.3% (958) were smokers and 4.3 % (169) were pan chewers while 6.3% (248) were users of both smoked and smokeless forms of tobacco. Significantly higher proportion of industrial laborers (49.9%) followed by drivers (24.1%) were found to be smokers (p=0.001). The prevalence of white lesions was higher in smokers versus non-smokers 3.5% versus 2.3% (p=0.111), however this difference was statistically non-significant. Red and white lesions were highly significant (i.e. 1.2 % and 10.9% respectively) in the subjects with pan chewing and smoking habits (p=0.001). A significant proportion (8.9%) of the subjects with pan chewing habit showed evidence of oral precancerous lesions (p=0.001). Conclusions: Even though smoking and pan chewing were two significant risk factors detected in this population, their prevalence and occurrence of premalignant lesions are low as compared to the studies conducted in their home countries.

• 대한심미치과학회지
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• 제6권1호
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• pp.10-17
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• 1997

It is pointed out that the color of composite resin is changing according to it's ploymerization and this color change is a harmful effect for the clinical satisfacion of composite resin restoration. The purpose of this study was to compare the changes of color of newly developed composite resins between before and after exposure of activating light. Five Compostie resins (8 shades) were employed: Palfique Estelite(UL, U, DY, G ; Tokuyama), Photo Clearfil A (US : Kuraray), Photo Clearfil Bright (US ; Kuraray), GC Graft LC(A3 ; GC), Silux Plus(U; 3M), Tristirnulus values of each material were determined before and after curing-light exposure by using a Micro Multi Photometer (MMP-1001, Nihon Denshoku Kogyo). The values were transformed into $L^*\;a^*\;b^*$ system and color changes of the resins were evaluated by the changes of $L^*$, $a^*$ and $b^*$ values for the individual shades. In addition, the effects of resin thickness and background color on color changes were also studied The finding were as follows: 1. Color changes of $L^*$, $a^*$ and $b^*$ values were recognized due to the light exposure for all products. The $b^*$ values of Palfique Estelite showed negligible changes for all shades. 2. The $b^*$ values were affected strongly by the background color, especially when decreasing the brightness on the background color.(Request original article reprints to Dr. Aoshima)

• 항공우주산업기술동향
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• 제6권2호
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• pp.99-108
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• 2008

본 논문에서는 우주인 선발부터 발사/귀환까지 한국 우주인 배출 사업을 전체적으로 정리하고 아울러 사업수행을 통해 얻은 기술 및 결과에 대해 자세히 소개될 것이다. 한국 우주인 배출 사업은 우주인 선발, 훈련, 우주실험 등과 관련된 유인우주기술을 습득하고 이 사업을 통해 국민들에게 과학과 우주에 대해 관심을 유도하여 과학문화를 확산하는 목적을 가지고 2005년 11월에 시작되었다. 2006년에는 우주인 선발 기준을 마련하고, 한국 우주인 배출을 위한 우주인 선발과정을 1차에서 4차까지 진행하여 우주인 2인을 최종 선발하였다. 그리고 2007년에는 우주인 2인이 러시아 가가린 훈련센터에서 우주인 훈련을 받았다. 그리고 한국 우주인이 국제우주정거장(ISS; International Space Station)에서 수행할 18가지의 우주과학실험과 3가지의 국제공동 실험을 개발하였다. 2008년 4월 한국 최초 우주인 이소연 박사가 카자흐스탄 바이코누르 발사장에서 소유즈 우주선을 타고 ISS로 올라가 계획된 우주실험 및 임무를 수행하고 무사히 귀환하였다. 위와 같이 본 논문에서는 이러한 일련의 과정(우주인 선발, 훈련, 우주실험 장비 개발 등)을 자세히 기술할 것이다.

• Journal of Forest and Environmental Science
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• 제31권3호
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• pp.164-176
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• 2015

Cyathea gigantea is a tree fern distributed throughout humid tropical regions of northeast India and other parts of the country. However, wild populations of this species are largely affected by various natural and anthropogenic activities. Therefore, an attempt was made to study the population structure and regeneration status of C. gigantea in and around greater Itanagar area of Papum Pare district, Arunachal Pradesh. Altogether 45 patches, ranging from 19.63 to $260m^2$ of area, were randomly sampled to study population structure and regeneration status of the species. Population study showed highest number of youngs in the height class of 0.50-0.75 m while, immatures were recorded highest in the height class of 2.0 to 2.5 m. Majority of the matures belonged to 6-9 m height class while it was recorded maximum in the diameter class of 10-15 cm. Average density of C. gigantea was $0.07individuals\;ha^{-1}$ which varied greatly among different patches with a range of 2 to 14. Significant correlations were found between patch size and density of youngs, immatures, matures and total density. Maximum concentration of youngs was observed in patch size $60-140m^2$, while for immatures, it was highest in patch size $20-160m^2$. Similarly, highest concentration of matures was observed in patch size $20-80m^2$ and $80-180m^2$. Population structure of the total population exhibited inverted pyramid shaped distribution. Population structure consisting of youngs, immatures, matures showed that around 60% patches lack of regenerating individuals which depict very poor natural regeneration of the species. Effective conservation strategies are therefore to be formulated to save C. gigantea from the threat of extinction in near future.

• 한국간호교육학회지
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• 제10권2호
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• pp.194-204
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• 2004

The purpose of this study was to provide the basic data needed to create more desirable psychological home environment and the prevention and relief of depression by examining the relations between psychological home environment and depression with the subjects of high school students. The study materials included standard questionnaires made up of forty two questions on psychological home environment by Dr. Jeong, Won-sik(1981), twenty one questions on depression indicators by Beck(1969). Collected data were analyzed by using SPSSWIN 10.0 Program through frequency, percentile, mean, standard deviation, t-test, ANOVA, Scheffe's test, and Pearson correlation coefficient. The main results of this study were as follows; Out of 210 perfect scores for the psychological home environment of the subjects, the mean was $140.54{\pm}11.21$, opening was $41.02{\pm}5.67$, affection was $37.59{\pm}5.80$, autonomy was $35.45{\pm}4.85$, and achievement was $26.48{\pm}6.79$. The depression of the subjects were slight, showing $13.78{\pm}9.73$, with normal condition (0-9scores) 40.0%, slight depression(10-15scores) 23.3%, mild depression(16-23scores) 20.3%, severe depression(24-63scores) 16.4%. The analyses of the relation between psychological home environment and depression of the subjects reveal that achievement-depression(r=.192, p=.000), opening-depression (r=-.296, p=.000), affection-depression(r=-.377, p=.000), and autonomy-depression(r=-.341, p=.000) has all meaningful relations. In summary, these data can be interpreted that high school students were likely to feel more depressed when they recognized their own home environment as under the burden of achievement, and to feel less depressed when they recognized it as open, affectionate, and autonomous.

• 천문학회보
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• 제37권1호
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• pp.48.1-48.1
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• 2012

We present the ultraviolet (UV) color-color relation of early-type galaxies (ETGs) in the nearby universe (0.05 < z < 0.12) to investigate the properties of hot stellar populations responsible for the UV excess (UVX). The initial sample of ETGs is selected by the spectroscopic redshift and the morphology parameter from the SDSS DR 7, and then cross-matched with the GALEX far-UV (FUV) and near-UV (NUV) GR6 data. The cross-matched ETG sample is further classified by their emission line characteristics in the optical spectra into quiescent, star-forming, and active galactic nucleus categories. Contaminations from early-type spiral galaxies, mergers, and morphologically disturbed galaxies are removed by visual inspection. By drawing the FUV-NUV (as a measure of UV spectral shape) versus FUV-r (as a measure of UVX strength) diagram for the final sample of -3700 quiescent ETGs, we find that the "old and dead" ETGs consist of a well-defined sequence in UV colors, the "UV red sequence," so that the stronger UVX galaxies should have a harder UV spectral shape systematically. However, the observed UV spectral slope is too steep to be reproduced by the canonical stellar population models in which the UV flux is mainly controlled by age or metallicity parameters. Moreover, 2 mag of color spreads both in FUV-NUV and FUV-r appear to be ubiquitous among any subsets in distance or luminosity. This implies that the UVX in ETGs could be driven by yet another parameter which might be even more influential than age or metallicity.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1539-1546
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• 2016

Specific patterns of the hereditary breast and ovarian cancer (HBOC) syndrome are related to mutations in the BRCA1 gene. One hundred unrelated breast cancer patients were interviewed to obtain clinical symptoms and signs, pedigree and familial history of HBOC syndrome related cancer. Subsequently, data were calculated using the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) risk prediction model. Patients with high score of BOADICEA were offered genetic testing. Eleven patients with high score of BOADICEA, 2 patients with low score of BOADICEA, 2 patient's family members and 15 controls underwent BRCA1 genetic testing. Mutation screening using PCR-HRM was carried out in 22 exons (41 amplicons) of BRCA1 gene. Sanger sequencing was subjected in all samples with aberrant graph. This study identified 10 variants in the BRCA1 gene, consisting of 6 missense mutations (c.1480C>A, c.2612C>T, c.2566T>C, c.3113A>G, c.3548 A>G, c.4837 A>G), 3 synonymous mutations (c.2082 C>T, c.2311 T>C and c.4308T>C) and one intronic mutation (c.134+35 G>T). All variants tend to be polymorphisms and unclassified variants. However, no known pathogenic mutations were found.