• Title/Summary/Keyword: DR-3

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Systematic Studies on the Fishes of the Family Cobitidae (Order Cypriniformes) in Korea: I. Three Unrecorded Species and Subspecies of the Genus Cobitis from Korea

  • Kim, Ik-Soo
    • The Korean Journal of Zoology
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    • v.23 no.4
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    • pp.239-250
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    • 1980
  • I would like to express my sincere gratitude to Dr. Ki Chul Choi, emeritus professor of Seoul National University and Dr. Il Young Joo, professor of Chung-ang University for their helpful advices, and Dr. T. Nalbant and Dr. P. Banarescu of National History Museum, Rumania, Mr. Y. Fusioka, associate professor of Yamaguchi University, Mr. K. Hosoya of Kyoto University, and Mr. Y. Sawada of Hokkaido University for their help in sending the specimens of C. taenia taenia and C. taenia striata by mail. I am also indebted to the Asan Foundation for the financial support of this research.

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Synthesis of Quinoxaline Derivatives at Room Temperature Using Magnetic Material Separated from Coal Fly Ash

  • Dhokte, Aashish O.;Sakhare, Mahadeo A.;Lande, Machhindra K.;Arbad, Balasaheb R.
    • Journal of the Korean Chemical Society
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    • v.57 no.1
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    • pp.73-80
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    • 2013
  • An efficient synthesis of quinoxalines derivatives is described using magnetic material separated from coal fly ash. Coal fly ash is a waste material generated in huge amount by burning of coal for the generation of electricity in thermal power station. It contains $SiO_2$, $Al_2O_3$ and magnetic material in significant amounts, from which magnetic material was separated by using magnetic separation method. These separated magnetic material further characterized by XPS, XRD, EDS, FTIR, SEM, TEM and BET techniques. The merits of present method are mild reaction conditions, and also excellent yields and short reaction times.

Gartanin enhances TRAIL-mediated liver cancer cell death through DR5 upregulation and autophagy activation

  • Dong-Oh Moon
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.53-59
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    • 2023
  • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has no effect on normal cells, but selectively can induce apoptosis in tumor cells. Gartanin, a xanthone compound in mangosteen, has been shown to inhibit cancer cell growth by arresting the cell cycle and inducing autophage. In this study, we revealed that gartanin can sensitize TRAIL-induced human liver cancer cell death. We also found that gartanin enhances DR5 expression, a death receptor for TRAIL. This effect appears to be related to CHOP activation associated with the response of endoplasmic reticulum stress. Gartanin treatment also inhibited p62 protein expression and cleaved LC3 to activate autophagy flux, which is related with TRAIL-induced cell death. Pretreatment with autophagy flux inhibitor, LY294002, inhibited gartanin-induced DR5 expression. In summary, our results reveal that the combined treatment of gartanin and TRAIL can be a valuable tool for cancer treatment.

The Effect of Cutting Positions and Temperature on the Rooting of Bitter Gourd (여주 삽목 시 삽수절단 위치와 온도조건이 발근에 미치는 영향)

  • Lee, Hee Ju;Lee, Sang Gyu;Kim, Sung Kyeom;Choi, Chang Sun;Kim, Sang Beom
    • Journal of Bio-Environment Control
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    • v.25 no.3
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    • pp.162-167
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    • 2016
  • This study was carried out to investigate proper stem cutting position and air temperature to regenerate roots from cuttings of bitter gourd. 'NS454' (NS) and 'Dragon' (DR) cultivars were tested and the cutting position was cut at the 3rd node in the stem (treatment I) and cut at the central part (stem segment) between 3rd leaf and 4th leaf in the stem (treatment II). The air temperature was maintained at 18, 23, 28 and $35^{\circ}C$ in the growth chambers, respectively. The photosynthetic photon flux at the ground of a chamber was maintained in approximately $150-200{\mu}mol\;m^{-2}s^{-1}$ during the 16-hour photoperiod. The relative humidity in the chambers was maintained over 85%. After 10 days of cuttings, regardless of cutting position, DR and NS cultivars showed 100% the survival rate in the $18^{\circ}C$ or $23^{\circ}C$ treatments, however, most of plants $18^{\circ}C$ treatment had not rooting. In the $28^{\circ}C$ treatment, regardless of cutting position, DR and NS cultivars showed 100% of the rooting rate. In the $23^{\circ}C$ treatment, for DR cultivar, the node cutting showed 90% of rooting rate and the stem segment cutting showed 40% rooting rate. For NS cultivar, the node cutting showed 50% of rooting rate and the stem segment cutting showed 40% rooting rate. DR and NS cultivars have high rooting rate, while the rooting rate remarkably decreased in the $35^{\circ}C$ treatment. For DR cultivar, the stem segment cutting showed 5.3 of the highest rooting number and the node cutting showed 2.7 rooting number in the $28^{\circ}C$ treatment. NS cultivar was not significantly different the rooting regardless of cutting position. The results suggested that cutting at the stem segment cutting of bitter gourd is an effective cutting method for increasing survival rate and the air temperature should be maintained at $28^{\circ}C$.

A Study on the bottom book of the 'Tripitaka Koreana'(高麗大藏經) and its carried book ("고려대장경"의 저본과 판각에 관한 연구)

  • 유부현
    • Journal of Korean Library and Information Science Society
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    • v.32 no.3
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    • pp.117-147
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    • 2001
  • This study researches to prove the character of the bottom book of the 'Tripitaka Koreana'and its carved book. From the research, it is Proved that the First Tripitaka 51books and the new Tripitaka that is the second Tripitaka collected in the Holim museum are the overtum cared books or the contracted overtum cared books of 'Tripitaka keybo'. And finds out some outline on the bottom and compared book used when published the new Tripitaka by comparing it by Sugi Buddhist priest: he published the new book using the Songbon(宋本) at first as the bottom book and compared it with the Kookbon(國本) and Danbon(丹本) and contracted it based on them. This corrected Songbon was used once more as the bottom book of the new Tripitaka. And It is grasped that some Tripitaka containing some serious mistakes and missed in Songbon was corrected based on the Kookbon and Danbon and caved it or made a new carved book to insert or substitute it to the new Tripitaka. study researches So this study concludes that such differences showing in these two books are on the bases of the gaps in time and space between them.

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A Pilot Study on Factors Associated with Presentation Delay in Patients Affected with Head and Neck Cancers

  • Baishya, Nizara;Das, Ashok Kumar;Krishnatreya, Manigreeva;Das, Anupam;Das, Kishore;Kataki, Amal Chandra;Nandy, Pintu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4715-4718
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    • 2015
  • Background: Patient delay can contribute to a poor outcome in the management of head and neck cancers (HNC). The main objective of the present study was to investigate the factors associated with patient delay in our population. Materials and Methods: Patients with cancers of the head and neck attending a regional cancer center of North East India were consecutively interviewed during the period from June 2014 to November 2014. The participation of patients was voluntary. The questionnaire included information on age, gender, residential status, educational qualification, monthly family income, any family history of cancer, and history of prior awareness on cancer from television (TV) program and awareness program. Results: Of 311 (n) patients, with an age range of 14-88 years (mean 55.4 years), 81.7% were males and 18.3% females (M:F=4.4). The overall median delay was 90 days (range=7 days-365 days), in illiterate patients the median delay was 90 days and 60 days in literate patients (P=0.002), the median delay in patients who had watched cancer awareness program on TV was 60 days and in patients who were unaware about cancer information from TV program had a median delay of 90 days (p=0.00021) and delay of <10 weeks was seen in 139 (44.6%) patients, a delay of 10-20 weeks in 98 (31.5%) patients, and a delay of 20-30 weeks in 63 (20.2%) patients. Conclusions: Education and awareness had a significant impact in reduction of median patient delay in our HNC cases.

Descriptive Epidemiology of Common Female Cancers in the North East India - a Hospital Based Study

  • Krishnatreya, Manigreeva;Kataki, Aamal Chandra;Sharma, Jagannath Dev;Nandy, Pintu;Talukdar, Abhijit;Gogoi, Gayatri;Hoque, Nazmul
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10735-10738
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    • 2015
  • Background: Cancers of the breast, uterine cervix and ovary are common cancers amongst females of North East India. Not much is known about the descriptive epidemiology of these cancers in our population. The present retrospective analysis was therefore performed. Materials and Methods: The data set available at the hospital based cancer registry of a regional cancer center of North-East India, containing information on patients registered during the period of January 2010 to December 2012, was applied. A total of 2,925 cases of breast, uterine cervix and ovarian cancer were identified. Results: Of the total, 1,295 (44.3%) were breast cancers, 1,214 (41.5%) were uterine cervix and 416 (14.2%) ovarian cancer, median age (range) for breast, uterine cervix and ovary were 45 (17-85), 48 (20-91) and 45 years (7-80), respectively. Some 43.5% of cases with uterine cervix patients were illiterate, 5.4% and 5.7% stage I in breast and cervix respectively and 96.4% of ovarian cancers in advanced stage. Conclusions: Improvement of female education can contribute to increase the proportion of early stage diagnosis of breast and uterine cervix in our population. Any population-based intervention for the detection of cancers of breast, uterine cervix and ovarian cancer should be started early in our population.

Lactobacillus reuteri DSM 17938 Improves Feeding Intolerance in Preterm Infants

  • Kaban, Risma K.;Wardhana, Wardhana;Hegar, Badriul;Rohsiswatmo, Rinawati;Handryastuti, Setyo;Amelia, Novie;Muktiarti, Dina;Indrio, Flavia;Vandenplas, Yvan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.6
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    • pp.545-553
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    • 2019
  • Purpose: Feeding tolerance is extremely important in preterm infants. This study aimed to evaluate whether preterm infants receiving Lactobacillus reuteri DSM 17938 would develop fewer symptoms of feeding intolerance. Secondary outcomes were duration of parenteral nutrition, time to reach full feeding, length of hospital stay, sepsis, necrotizing enterocolitis (NEC), diarrhea, and mortality. Methods: This double-blind randomized controlled trial of L. reuteri DSM 17938 versus placebo included 94 neonates with a gestational age of 28-34 weeks and birth weight of 1,000-1,800 g. Results: Feeding intolerance (vomiting and/or distension) was less common in the probiotic group than in the placebo group (8.5% vs. 25.5%; relative risk, 0.33; 95% confidence interval, 0.12-0.96; p=0.03). No significant intergroup differences were found in proven sepsis, time to reach full feeding, length of hospital stay, or diarrhea. The prevalence of NEC (stages 2 and 3) was 6.4% in the placebo group vs. 0% in the probiotic group (relative risk, 1.07; 95% confidence interval, 0.99-1.15; p=0.24). Mortality rates were 2.1% in the probiotic group and 8.5% in the placebo group, p=0.36). Conclusion: The administration of L. reuteri DSM 17938 to preterm infants was safe and significantly reduced feeding intolerance. No significant differences were found in any other secondary outcomes.

Comparison between 24-hour diet recall and 24-hour urine collection for estimating sodium and potassium intakes and their ratio among Korean adults

  • Taisun Hyun;Mi-Kyeong Choi;Young-Ran Heo;Heekyong Ro;Young-Hee Han;Yeon-Kyung Lee
    • Nutrition Research and Practice
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    • v.17 no.2
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    • pp.284-296
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    • 2023
  • BACKGROUND/OBJECTIVES: This study aimed to compare 24-h diet recall (DR) and 24-h urine collection (UC) for estimating sodium and potassium intakes and their ratio (Na/K), identifying factors associated with sodium and potassium intakes and Na/K, and identifying those who were likely to underestimate sodium and potassium intakes by DR. SUBJECTS/METHODS: A total of 640 healthy adults aged 19-69 yrs completed a questionnaire survey, salty taste assessment, anthropometric measurement, two 24-h DRs, and two 24-h UCs. RESULTS: The mean sodium and potassium intakes and Na/K were 3,755 mg/d, 2,737 mg/d, and 1.45 according to DR, and 4,145 mg/d, 2,812 mg/d, and 1.57 according to UC, with percentage differences of -9.4%, -2.7%, and -7.6% in the values between the two methods, respectively. Men, older adults, smokers, obese individuals, those who consumed all the liquid in the soup, and those who were found to be salty in the salty taste assessment consumed significantly more sodium; older adults, the heavy- activity group, and obese individuals consumed more potassium; and men, younger adults, smokers, and obese individuals had a significantly higher Na/K, according to UC. Compared with UC, DR was more likely to underestimate sodium intake in older adults, smokers, obese individuals, those who consumed all the liquid in the soup, and those who consumed eating-out/delivery food at least once a day, and potassium intake in older adults, the heavy-activity group, and obese individuals. CONCLUSIONS: The mean sodium and potassium intakes and Na/K estimated by DR were comparable to those measured by UC. However, the association of sodium and potassium intakes with sociodemographic and health-related factors showed inconsistent results when estimated by DR and UC. Factors influencing the underestimation of sodium intake by DR compared to UC should be further investigated.

The Study on Design of the 5kW Class Inline Micro-Turbine (5kW급 인라인 마이크로 수차 설계에 대한 연구)

  • Park, Sang-Eun;Roh, Hyung-Woon
    • The KSFM Journal of Fluid Machinery
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    • v.15 no.3
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    • pp.32-38
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    • 2012
  • This paper is aimed to propose the design database(DB) of the inline micro-turbine for 5kW class. CFD analysis is performed to investigate the effect of a turbine on each parameter. This study showed that RadhaKrishna's data is different from the 5kW class in the low-head and the micro-turbine. Therefore, new DB for the design of inline micro-turbine for 5kW class could be needed. This study configured new design DB for the design of inline micro-turbine for 5kW class. The DB of this study showed that the optimal hub ratio(Dp/DR), the optimal body ratio(Db/DR) and the optimal range of body length ratio(Lh/DR) is 50%, 1.1 and 2.3 to 2.9, respectively.