• Journal of Institute of Control, Robotics and Systems
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• v.14 no.11
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• pp.1189-1195
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• 2008

We introduce a MEMS-based pedestrian dead reckoning (PDR) system. A walking navigation algorithm for pedestrians is presented and map-matching algorithm for the navigation system based on dead reckoning (DR) is proposed. The PDR is equipped on the human body and provides the position information of pedestrians. And this is able to be used in ubiquitous sensor network (USN), U-hearth monitoring system, virtual reality (VR) and etc. The PDR detects a step using a novel technique and simultaneously estimates step length. Also an azimuth of the pedestrian is calculated using a fluxgate which is the one of magnetometers. Map-matching algorithm can be formulated to integrate the positioning data with the digital road network data. Map-matching algorithm not only enables the physical location to be identified from navigation system but also improves the positioning accuracy. However most of map-matching algorithms which are developed previously are for the car navigation system (CNS). Therefore they are not appropriate to implement to pedestrian navigation system based on DR system. In this paper, we propose walking navigation system and map-matching algorithm for PDR.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.09a
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• pp.307-310
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• 2003

In the maritime container terminal, LMTT(Linear Motor-based Transfer Technology) is horizontal transfer system for the yard automation, which has been proposed to take the place of AGV(Automated Guided Vehicle). The system is based on PMLSM (Permanent Magnetic Linear Synchronous Motor) that is consists of stator modules on the rail and shuttle car (mover). Because of large variant of mover's weight by loading and unloading containers, the difference of each characteristic of stator modules, and a stator module's trouble etc., LMCPS (Linear Motor Conveyance Positioning System) is considered as that the system is changed its model suddenly and variously. In this paper, we will introduce the soft-computing method of a multi-step prediction control for LMCPS using DR-FNN (Dynamically-constructed Recurrent Fuzzy Neural Network). The proposed control system is used two networks for multi-step prediction. Consequently, the system has an ability to adapt for external disturbance, cogging force, force ripple, and sudden changes of itself.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.46 no.6
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• pp.58-64
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• 2009

Digital radiography (DR) images are corrupted by the additive noise, and also distorted by system impulse response. These unwanted phenomena are obstacles to obtain the desired image. To recover the original image, we applied multiscale Wiener filters in wavelet domain for DR images. The multiscale Wiener filter is first proposed by Chen for the restoration of fractal signals which are distorted by the system impulse response and additive noise. In this paper, we extended the multiscale Wiener filter to the two dimensional data. To compare the performance of ours with others, some simulations are given for a couple of wavelet filters with different wavelet levels, system impulse reponses and various noise power. When the addive noise powers are between 20-32 dB, the signal to noise ratio(SNR) of the proposed system is 0.5-2.0 dB better than that of the traditional Wiener filter method.

• Korean Journal of Microbiology
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• v.54 no.4
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• pp.330-342
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• 2018

The Streptavidin and Biotin system has been studied most extensively as the high affinity non-covalent binding of Biotin to STR ($K_D=10^{-14}M$) and four Biotin binding sites in tetrameric Streptavidin makes this system useful for the production of multivalent antibody. For the application of this system, we cloned Streptavidin amplified from Streptomyces avidinii chromosome by PCR and fused to gene of hAY4 single-chain Fv antibody specific to death receptor 4 (DR4) which is a receptor for tumor necrosis factor ${\alpha}$ related apoptosis induced ligand. The hAY4 single-chain Fv antibody fused to Streptavidin expressed in Escherichia coli showed 43 kDa monomer in heated SDS-PAGE. However, this fusion protein shown in both non-heated SDS-PAGE and Size-exclusion chromatography exhibited 172 kDa as a tetramer suggesting that natural tetramerization of Streptavidin by non-covalent association induced hAY4 single-chain Fv tetramerization. This fusion protein retained a Biotin binding activity similar to natural Streptavidin as shown in Ouchterlony assay and ELISA. Death receptor 4 antigen binding activity of purified hAY4 single-chain Fv fused to Streptavidin was also confirmed by ELISA and Westernblot. In addition, surface plasmon resonance analysis showed 60-fold higher antigen binding affinity of the hAY4-STR than monomeric hAY4 ScFv due to tetramerization. In summary, hAY4 single-chain Fv fused to Streptavidin fusion protein was successfully expressed and purified as a soluble tetramer in E. coli and showed both Biotin and DR4 antigen binding activity suggesting possible production of bifunctional and tetrameric ScFv antibody.

• Journal of Korean Academy of Nursing
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• v.22 no.4
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• pp.569-588
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• 1992

This study examined the relationship between the experience of stressful life events and somatic symptoms of urban women. Data were collected by interviewing 200 women from June to July 1, 1991. Vsable data work obtained from 162 of the women. Modified version of a stressful life events measurement tool developed p.5. Lee (1984) and the Somatic Discomfort Inventory by Wittenborn were used to measure the variables. Data were processed by an 5.p.5.5. program and analyzed. statistically for percentage, T-test, ANOYA and Pearson Correlation coefficient. Result of the Study are as follows : 1) The group total mean score of stressful life events was 92.66 $\pm$ 10.41. The higher scores in the $\boxDr$Test and school$\boxUl$ of the Extrapersonal factor, in the $\boxDr$Health problems$\boxUl$ of the Intrapersonal factor and $\boxDr$Conflict and differences within the family$\boxUl$ of the Interpersonal factor, factors. which a suggested by Neuman's model. 2) The group total mean score for somatic symptoms was 100.41$\pm$9.74. The higher scores were for the factors of $\boxDr$Fatigue (1.94)$\boxUl$, $\boxDr$Menopause (1.74)$\boxUl$, $\boxDr$Muscular system(1.67)$\boxUl$ and $\boxDr$Sleeping (1.67)$\boxUl$ 3) The mean scores of stressful life events were higher in the 40~60 age group, for middle school graduates(P＜.05), career women and those in nuclear families (P＞.05). 4) The mean scores of somatic symptoms were higher in the 45~60 age group, for middle school graduates, non career women and women with 5 or more children(P＜.05). 5) There was a positive correlation between the scores of stressful life events and somatic symptoms (r＝.585 P＜.05). The higher the level of stressful life events the higher the score of somatic symptoms, the results were consistent with the Extrapersonal, Intrapersonal and Interpersonal stress factors of Neuman's Health Care Systems. This research assessed the stressful life events of women, who play the most important role in the family for illness prevention and health promotion and suggested the importance of programs in the Primary Health Services to build basic coping resources.

• Journal of Life Science
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• v.24 no.9
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• pp.927-934
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• 2014

Sanguinarine, a benzophenanthridine alkaloid originally derived from the root of Sanguinaria canadensis, has been shown to possess antimicrobial, antioxidant, and anti-cancer properties. Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is known to induce apoptosis in cancer cells, but not most normal cells and has shown efficacy in a phase 2 clinical trial, development of resistance to TRAIL by tumor cells is a major roadblock. Our previous study indicated that treatment with TRAIL in combination with subtoxic concentrations of sanguinarine sensitized TRAIL-mediated apoptosis in TRAIL-resistant human gastric carcinoma AGS cells; however, the detailed mechanisms are not fully understood. In this study, we show that sanguinarine sensitizes AGS cells to TRAIL-mediated apoptosis as detected by MTT assay, agarose gel electrophoresis, chromatin condensation and flow cytometry analysis. Combined treatment with sanguinarine and TRAIL effectively induced expression of death receptor (DR) 5 but did not affect expression of DR4 and mitogen activated protein kinases signaling molecules. Moreover, the combined treatment with sanguinarine and TRAIL increased the generation of reactive oxygen species (ROS); however, N-acetylcysteine, ROS scavenger, significantly recovered growth inhibition induced by the combined treatment. Taken together, our results indicate that sanguinarine can potentiate TRAIL-mediated apoptosis through upregulation of DR5 expression and ROS generation.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2004.04a
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• pp.103-106
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• 2004

Nowadays it is necessary to manage the road system effectively because of the explosive increment of vehicle and goods. To resolve this problems through the fast upgrade of information about position and time of moving vehicle, the combined navigation system using GPS and complementary navigation system, i.e. INS, DR, etc. has been used. Although GPS is popular for the vehicle navigation system, this is not useful for the kinematic positioning of the vehicles in the urban canyon because of its few satellites. Therefore, this study deals with the kinematic positioning of the vehicles with GPS CORS to GPS navigation. For this, first the static single point positioning of GPS and GPS for reference station was performed to evaluate the accuracy of GPS positioning. Next, in the post-processed, the DGPS (Differential GPS) was performed for the kinematic positioning of the vehicles. So, it is expected that GPS CORS can be applicable to the control of traffic flow, the effective management of road system, and the development of ITS and it is regarded that the combined navigation system of vehicles with GPS, INS, and DR, etc. should be studied constantly.

• Proceedings of the KIEE Conference
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• 1996.07a
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• pp.95-97
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• 1996

Circular coils are widely used in electromagnetic applications, and the force in a sets of coils consisting of more than two can be divided into three components. Among them, one component called radial force is acting on the radial axis, and it is exposed as stree or impact. Calculation of the radial force was used to be performed by introducing Ampear's law of force which is $F=J{\times}B$. However, many cases in analyzing a system, calculation method from the mutual inductance between the coils is oftenly employed to get the axial force and resulting dynamics. In this case, if the calculation of radial force from the mutual inductance is possible, flow of the calculation for the system analysis would be much more simpler.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.8
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• pp.1074-1079
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• 2013

Demand response(DR) is potential generation alternative to improve the reliability indices of system and load points. However, when demand resources scheduled in DR market fail to reduce demand, it can create new problems associated with maintaining a reliable supply. In this paper, a reliability model of demand resource is constructed considering customers' behaviors in the same form as conventional generation units, where availability and unavailability are associated with the simple two-state model. As a result, the generalized reliability model of demand resources is represented by multi-state model.

• International Journal of Ocean System Engineering
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• v.1 no.2
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• pp.102-109
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• 2011

This paper describes the implementation of a precise underwater navigation solution using a multiple sensor fusion technique based on USBL, GPS, DVL and AHRS measurements for the operation of a remotely operated mine disposal vehicle (MDV). The estimation of accurate 6DOF positions and attitudes is the key factor in executing dangerous and complicated missions. To implement the precise underwater navigation, two strategies are chosen in this paper. Firstly, the sensor frame alignment to the body frame is conducted to enhance the performance of a standalone dead-reckoning algorithm. Secondly, absolute position data measured by USBL is fused to prevent cumulative integration error. The heading alignment error is identified by comparing the measured absolute positions with the DR algorithm results. The performance of the developed approach is evaluated with the experimental data acquired by MDV in the South-sea trial.