• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.12
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• pp.247-253
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• 2013

The purpose is a comparative evaluation in the DR System according to the dosimetry and image quality of the quantitative and objective via Direct digital radiography, Indirect digital radiography, Image intensifier (Charge Coupled Device type) digital radiography. The experimental method used rando phantom and measured the entrance surface dose. And through using the measured entrance surface dose and then using the PCXMC program were evaluated risk due to irradiation and the effective dose. SNR and NPS and CNR were measured and analyzed by using 21cm acryl phantom. Significance of measured value was evaluated by statistics method. Entrance surface dose, major organ dose, effective dose all of them were measured the lowest rated in direct DR when it is on the basis of direct DR dose, high-dose ratio were measured in I.I DR approximately 1.3 times, indirect DR approximately 2.4 times. Risk in accordance with radiation also was measured same as dose ratio. On the conclusion that SNR measurement result based on direct DR SNR measurements, low-SNR ratio were measured in I.I DR approximately 7.25 times, indirect DR approximately 1.48 times. On the conclusion that CNR measurement result based on direct DR CNR measurements, high-dose ratio were measured in I.I type DR approximately 1.16 tims and low-dose ratio were measured in indirect DR approximately 0.87 times. Therefore Direct DR system using a-selenium sensing element to detect x-ray photon is thought effectively at the examination such as infant to sensitive irradiation and the genital gland. Because quality image is built by low dose. Also when it is necessary that image test requiring many diagnosis information, indirect DR system is thought effectively.

• Journal of Smart Tourism
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• v.3 no.1
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• pp.1-8
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• 2023

• Korean Journal of Head & Neck Oncology
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• v.13 no.1
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• pp.16-23
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• 1997

Although normal thyroid epithelial cells do not constitutively express HLA-DR antigen, their expression in wide spread within thyroid glands obtained from the human with autoimmune thyroid disease and with many neoplastic thyroids. We have, therefore, studied immunohistochemically with regard to the expression of HLA-DR antigen of thyroidectomy specimens from 50 patients of various thyroid diseases with use of paraffin-embedded tissue. One or two sections from each case were stained with commercially available mouse monoclonal antibody for class II HLA-DR antigen(HLA-DR/Alpha, DAKO) and examined by semiquantitative counting system for thyrocytes, neoplastic thyrocytes and other cells expressing HLA-DR antigen. All patients with lymphocytic thyroiditis(2/2) and diffuse hyperplasia(Graves' disease)(5/5), most patients with Hashimoto's disease(9/ll) expressed HLA-DR antigens in thyrocyte with abundant HLA-DR expressing lymphocytic infiltrates with lymph follicle formation in its vicinity or adjacent to the lesion. Most patients with papillary carcinoma(9/1l) had HLA-DR antigen detected in malignant thyrocytes ; while follicular carcinoma(0/3) and follicular adenoma(0/5) did not have detactable HLA-DR immunoreactivity. Adenomatous goiter(3/7) had HLA-DR antigen detected focally in lesser than half cases. Conversely, in four papillary carcinomas and three adenomatous goiters, HLA-DR expression of thyrocytes was found in the absence of HLA-DR expressing lymphoid infiltrates. In such cases therefore other factors more than thyroid autoimmunity must be causative for HLA-DR immunoreactivity. The results of this study indicate as follows. 1) The expression of HLA-DR on thyrocytes involved in autoimmune reactions appeared to be secondary to cytokine release from associated lymphocytic infiltrates. 2) Thyrocytes in thyroid lesions with equal degrees of lymphocytic infiltration without HLA­DR expression exhibited no HLA-DR immunoreactivity. 3) In neoplastic thyrocytes, most papillary carcinoma(9/11) exhibited detactable HLA-DR expression, while follicular carcinoma/adenoma(0/3/0/5) exhibited no detactable HLA-DR immunoreactivity which suggest the existence of divergent mechanisms inducing and modulating HLA-DR expression of different types of neoplastic thyrocytes.

• Journal of Advanced Navigation Technology
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• v.9 no.2
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• pp.147-155
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• 2005

In this paper, we propose that three uniform coplanar waveguides(CPWs), such as a conventional, finite grounded(FG), and grounded(G) CPWs, can be coupled with a $TE_{01{\delta}}$ mode dielectric resonator(DR) for a parallel resonant characteristic as a microstrip line coupled with the DR. Coupling characteristics have been investigated by placing the DR on a dielectric support above the CPWs and by moving the DR away from the center of a slot of the CPWs to the ground plane. FEM simulation(HFSS) results in terms of S-parameters agree well with measurement results. Finally, unloaded Q values of the DR coupled with the three uniform CPWs are compared with those of the DR coupled with a microstrip line. The comparison shows that the DR coupled with the three CPWs has higher unloaded Qs than that coupled with a microstrip line and that the GCPW case has the highest unloaded Qs.

• Clinical and Experimental Pediatrics
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• v.64 no.7
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• pp.370-372
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• 2021

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.10
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• pp.1279-1286
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• 1999

In conventional GPS/DR integration schemes, the GPS position (or pseudo-range) information is used in calibrating DR sensors. In those schemes, however, an inaccurate calibration may degrade the position accuracy when the GPS measurement is not available. This paper presents a new integration scheme where the GPS velocity information is used in calibrating DR sensors. Also proposed is a new error model of DR sensors for calibrating the bias error and the tilt error in dynamic environments. The proposed model makes it possible that the errors of both the DR sensor parameters and the velocity are calibrated using the GPS carrier-based velocity(or the pseudo-range rate) measurement while the DR position error is calibrated using the GPS position measurement. Since the DR sensors are calibrated accurately, the positioning accuracy is drastically improved when the GPS measurements are unavailable.

• Communications for Statistical Applications and Methods
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• v.28 no.5
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• pp.553-562
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• 2021

Directional regression (DR; Li and Wang, 2007) is well-known as an exhaustive sufficient dimension reduction method, and performs well in complex regression models to have linear and nonlinear trends. However, the extension of DR is not well-done upto date, so we will extend DR to accommodate multivariate regression and large p-small n regression. We propose three versions of DR for multivariate regression and discuss how DR is applicable for the latter regression case. Numerical studies confirm that DR is robust to the number of clusters and the choice of hierarchical-clustering or pooled DR.

• ETRI Journal
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• v.28 no.2
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• pp.131-144
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• 2006

This work demonstrates a dead-reckoning (DR) scheme for a low-cost land navigation system and a DR/GPS system design using the sigma point Kalman filter (SPKF). T hrough an observability analysis and some simulations, it is shown that the performances of a stand-alone DR system and DR/GPS system can be improved by employing the proposed DR scheme and SPKF. By using the designed DR scheme and filter, the stand-alone DR system does not have any undetectable errors occurring on the curve trajectory. And the DR/GPS system can provide a stable and seamless navigational solution even in the case where the initial heading estimation error is large, such as 160 degrees, or when the GPS signal is unavailable due to tunnels, buildings, and so on. Simulation results indicate a satisfactory performance of the proposed system.

• Journal of Advanced Navigation Technology
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• v.2 no.2
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• pp.75-83
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• 1998

This paper presents a low cost and high accuracy integrated Global Positioning System (GPS)/dead reckoning (DR) system. The integrated GPS/DR system is capable of providing highly accurate position data in real-time or in post processing. Based on the analysis of the main error source affecting the DR measurements, an eight-state mathematical model for the integrated system has been developed to represent these errors. This eight-state model has been used to build a nonlinear filter for the estimation of the state vector at every epoch when DR measurements are available. The accuracy of the system has been evaluated using 1Hz DR measurements and 3Hz continuous GPS position estimates. Through numerical simulation the system performance during periods with GPS outage has been investigated by comparing two different noise models. While one model is the position estimation filter containing a single noise model, the other filter includes two-level noise model. The simulation results have shown that the estimation filter containing two-level noise model for computing the position error of the integrated GPS/DR system yields better performance than that the filter including the single-level noise model does.

• Journal of Periodontal and Implant Science
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• v.53 no.1
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• pp.54-68
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• 2023

Purpose: The purpose of this study was to determine whether metformin (MF) could alleviate the expresssion of reactive oxygen species (ROS) and improve the osteogenic ability of bone marrow mesenchymal stem cells derived from diabetic rats (drBMSCs) in vitro, and to evaluate the effect of MF on the ectopic osteogenesis of drBMSCs in a nude mouse model in vivo. Methods: BMSCs were extracted from normal and diabetic rats. In vitro, a cell viability assay (Cell Counting Kit-8), tests of alkaline phosphatase (ALP) activity, and western blot analysis were first used to determine the cell proliferation and osteogenic differentiation of drBMSCs that were subjected to treatment with different concentrations of MF (0, 50, 100, 200, 500 µM). The cells were then divided into 5 groups: (1) normal rat BMSCs (the BMSCs derived from normal rats group), (2) the drBMSCs group, (3) the drBMSCs + Mito-TEMPO (10 µM, ROS scavenger) group, (4) the drBMSCs + MF (200 µM) group, and (5) the drBMSCs + MF (200 µM) + H₂O₂ (50 µM, ROS activator) group. Intracellular ROS detection, a senescence-associated β-galactosidase assay, ALP staining, alizarin red staining, western blotting, and immunofluorescence assays were performed to determine the effects of MF on oxidative stress and osteogenic differentiation in drBMSCs. In vivo, the effect of MF on the ectopic osteogenesis of drBMSCs was evaluated in a nude mouse model. Results: MF effectively reduced ROS levels in drBMSCs. The cell proliferation, ALP activity, mineral deposition, and osteogenic-related protein expression of drBMSCs were demonstrably higher in the MF-treated group than in the non-MF-treated group. H₂O₂ inhibited the effects of MF. In addition, ectopic osteogenesis was significantly increased in drBMSCs treated with MF. Conclusions: MF promoted the proliferation and osteogenic differentiation of drBMSCs by inhibiting the oxidative stress induced by diabetes and enhenced the ectopic bone formation of drBMSCs in nude mice.