• Bulletin of the Korean Chemical Society
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• v.15 no.3
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• pp.198-204
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• 1994

Chemical shifts in aqueous sodium dodecylsulfate(SDS) micellar solution solublizing phenol, catechol, resorcinol, hydroquinone have been measured to investigate solubilization properties. Proton nuclear magnetic resonance frequencies of solubilizates as well as those of the ${\alpha}$-methylene, middle methylene and terminal methyl of SDS shift linearly as a function of solubilizate concentration. From the plots of observed chemical shift (v) vs solubilizate concentration, slope (a) and solubilizate free chemical shift ($v_0$) are obtained. They are very informative to solubilization site of the systems. Catechol and phenol solubilized SDS and catechol solubilized dodecylpyridinium chloride(DPC), dodecyltrimethylammonium bromide(DTAB) systems are studied using the same method to compare head group effect and middle methylene proton signal splitting. It is proposed that phenol and catechol are inserted into micellar interior and the number of methylenes assigned to the higher field peaks is 5.0${\pm}$0.5.

• Annual Conference of KIPS
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• 2022.11a
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• pp.60-62
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• 2022

SYCL은 OpenCL 디바이스를 위해 추상화한 C++ 프로그래밍 모델이다. OpenCL에 비해 SYCL은 높은 생산성 등 C++이 가지고 있는 강점을 보유하며, 인텔이 이기종 컴퓨팅을 위한 개발 언어로 SYCL 기반의 DPC++을 출시함에 따라 많은 주목을 받고 있다. 우리는 여러 SYCL 구현물들 중에서 NVIDIA, AMD 등 다양한 GPU를 지원하고, 코드의 수정 및 추가가 용이한 hipSYCL를 채택하여 여러 연구를 진행하고 있다. 본 논문에서는 hipSYCL 구조 내에 AMD GPU를 위한 HIP 백엔드 플러그인을 대체할 수 있는 새로운 백엔드 플러그인을 제안한다. 이 플러그인은 HSA 런타임 API를 사용하여 기존의 플러그인보다 계층 구조를 줄이고 경량화하였다.

• Journal of the Korean Chemical Society
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• v.31 no.4
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• pp.308-314
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• 1987

The adsorption behavior of some chelating agents on the Amberlite XAD-7 resin was studied to obtain the optimum conditions for the preparation of chelating agent-XAD-7 resins. The chosen chelating agents are cupferron (CP), diphenylcarbazone (DPC), salicylaldoxime (SAO), thiosalicylic acid (TSA), and dimethylglyoxime (DMG), which have been well known chelating agents to Cu(Ⅱ) and Ni (Ⅱ) ions. Among the chelating agent-XAD-7 resins, SAO-XAD-7 and DMG-XAD-7 resins were evaluated as appropriate impregnated resins by investigating their stabilities in the wide pH range and high abilities to adsorb Cu(Ⅱ) and Ni(Ⅱ) ions. The selective adsorption of Cu(Ⅱ) from Ni(Ⅱ) was possible by changing pH condition by SAO-XAD-7 resin. The adsorption capacities of SAO-XAD-7 and DMG-XAD-7 for Cu(Ⅱ) were $7{\times}10^{-3}mmol$ Cu(Ⅱ) per gram of resin and $2{\times}10^{-3}mmol$ Cu(Ⅱ) per gram of resin, respectively. The quantitative recovery of Cu(Ⅱ) adsorbed by the resin was demonstrated. The adsorption behavior of Cu(Ⅱ) and Ni(Ⅱ) by the single and mixed bed of chelating agent-XAD-7 resin was discussed.

• BMB Reports
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• v.45 no.4
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• pp.253-258
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• 2012

The dermal papilla cells (DPCs) of hair follicles are known to secrete paracrine factors for follicular cells. Shotgun proteomic analysis was performed to compare the expression profiles of the secretomes of human DPCs and dermal fibroblasts (DFs). In this study, the proteins secreted by DPCs and matched DFs were analyzed by 1DE/LTQ FTICR MS/MS, semi-quantitatively determined using emPAI mole percent values and then characterized using protein interaction network analysis. Among the 1,271 and 1,188 proteins identified in DFs and DPCs, respectively, 1,529 were further analyzed using the Ingenuity Pathway Analysis tool. We identified 28 DPC-specific extracellular matrix proteins including transporters (ECM1, A2M), enzymes (LOX, PON2), and peptidases (C3, C1R). The biochemically-validated DPC-specific proteins included thrombospondin 1 (THBS1), an insulin-like growth factor binding protein3 (IGFBP3), and, of particular interest, an integrin beta1 subunit (ITGB1) as a key network core protein. Using the shotgun proteomic technique and network analysis, we selected ITGB1, IGFBP3, and THBS1 as being possible hair-growth modulating protein biomarkers.

• Journal of Environmental Impact Assessment
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• v.22 no.3
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• pp.219-230
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• 2013

Species distribution modeling is one of the most effective habitat analysis methods for wildlife conservation. This study was for evaluating the suitability of species distribution to distance between forest patches in Seoul city using tits. We analyzed the distribution of the four species of tits: varied tit (Parus varius), marsh tit (P. palustris), great tit (P. major) and coal tit (P. ater), using the landscape indexes and connectivity indexes, and compared the resulting suitability indexes from 100m to 1,000m. As factors affecting to the distribution of tits, we calculated landscape indices by separating them into intra-patch indices (i.e. logged patch area (PA), area-weighted mean patch shape index (PSI), tree rate (TR)) and inter-patch indices (i.e. patch degree (PD), patch betweenness (PB), difference probability of connectivity (DPC)), to analyze the internal properties of the patches and their connectivity by tits occurrence data using logistic regression modeling. The models were evaluated by AICc (Akaike Information Criteria with a correction for finite sample sizes) and AUC (Area Under Curve of ROC). The results of AICc and AUC showed DPC, PA, PSI, and TR were important factors of the habitat models for great tit and marsh tit at the level of distance 500~800m. In contrast, habitat models for coal tit and varied tit, which are known as forest interior species, reflected PA, PSI, and TR as intra-patch indices rather than connectivity. These mean that coal tit and varied tit are more likely to find a large circular forest patch than a small and long-shaped forest patch, which are higher rate of forest. Therefore, different strategies are required in order to enhance the habitats of the forest birds, tits, in a region that has fragmented forest patches such as Seoul city. It is important to manage forest interior areas for coal tit and varied tit, which are known as forest interior species and to manage not only forest interior areas but also connectivity of the forest patches in the threshold distance for great tit and marsh tit as adapted species to the urban ecosystem for sustainable ecosystem management.

• Journal of Plant Biology
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• v.35 no.3
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• pp.247-252
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• 1992

The effect of iso-butanol on the electron transport rate of PS I and PS II was investigated in isolated spinach chloroplasts. In photosystem I, the rate of electron transport increased in the presence of 1 to 4% of isobutanol but decreased in 5 to 9% of iso-butanol. But in photosystem II, the rate of electron transport decreased when treated with 0.2 to 1% of iso-butanol. The inhibitory effect of isomers of butanol on PS II electron transport rate increased in the order of 2-butanol, tert-butanol, iso-butanol and I-butanol. This means that PS II activity was affected according to the arrangement of carbon atoms in butanol. The inhibitory effect of iso-butanol reduced when DPC was added in the solution. This means that iso-butanol affects PS II reduction side of thylakoid membrane primarily. The inhibitory effect of iso-butanol was reduced when $Mn^{2+},\;C^{2+}$ or BSA were added in the solution. PS II activity was restored when 1% iso-butanol treated chloroplast solution was diluted to twentyfold or when $Mn^{2+},\;C^{2+}$ or BSA was added to the diluted solution. However, the SDS-PAGE banding pattern of thylakoid membrane proteins was similar even in 2% iso-butanol treated chloroplasts and the control ones. Only in 5% iso-butanol treated chloroplasts these bands were very weak. These observations suggest that low concentrations of iso-butanol releases manganese and calcium ions from chloroplasts and inhibits the electron transport system. This inhibitory effect can be reversible in low concenterations but in high concentrations the inhibitory effect of iso-butanol become irreversible.rsible.

• Journal of Korean Biological Nursing Science
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• v.3 no.1
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• pp.1-10
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• 2001

뇌손상이라고 하는 과도한 stress를 받았을 때 free cortisol의 분비되는 양과 urinary free cortisol의 circadian 리듬에 어떻게 영향을 주는지 확인하기 위하여 시도하였다. 연구대상은 대조군은 건강한 젊은 여성 6명과 실험군응 CT상 뇌에 손상을 받은 4명의 여성으로 30대 환자이었다. 담당의사와 중환자실 관리책임자의 동의하에서 시도되었으며, 실험기간은 2000년 7월 1일에서 7월 10일까지였다. 대조군과 실험군의 뇨를 채취하여 뇨중 free cortisol 농도의 circadian rhythm을 알아보기 위해 채뇨 후 분석하였다. 채뇨는 뇌손상을 받고 응급실을 통해 신경외과 중환자실에 입원한 지 5시간 이내에 해당된 환자로 24시간 유지되는 foley catherization 상태하에서 12:00부터 3일동안 72시간을 2시간 간격으로 채뇨하였고, 대조군은 오전 12시부터 24시간 동안 2시간 간격으로 채뇨하였다. 측정방법으로는 cortisol의 정량은 solid-phase radioimmuoassay 방법을 이용하였으며, 분석재료는 Coat-A-Count(R) Cortisol kit(DPC, U.S.A.)을 사용하여 DPC사의 측정방법을 따랐다. 연구대상자의 free cortisol의 총량은 대조군에서는 $42.8{\mu}g$이었고, 실험군은 1일에 $991.2{\mu}g$, 2일에 $809{\mu}g$, 3일에 $544.2{\mu}g$으로 대조군과 통계적으로 유의한 차이를 나타내(p<.05), 실험군에서 현저하게 증가된 양상을 보였고, 시간이 지나면서 점점 감소하는 경향을 나타냈다. 시간별로 t-검정으로 분석한 결과로는 모든 시간대에서 대조군과 실험군의 평균치는 통계적으로 유의한 차이를 나타냈다. Free cortisol의 circadian에서는 대조군에서는 정상인의 cortisol의 circadian의 경우와 같은 리듬을 보였으나, 손상을 받은 실험군의 경우 분비량은 현저하게 증가했음을 보여주었다. 최고치가 제1일에 18:00과 다음날 10:00에 나타나 최고치가 2회 나타났으며, 제2일에도 제1일과 마찬가지로 18:00에 나타났고, 제3일에는 24:00에 나타나 제1일보다 제2일에는 최고치가 한 번 나타난 리듬을 보여주었고, 분비량은 2일에 감소하였다. 제3일에는 최고치가 8시간 지연된 나타난 리듬의 변화를 보여주었다. 최저치는 제1일, 제2일, 제3일 모두 24:00에 나타난 리듬을 보여주었다. 이상의 결과에서 실험군인 뇌손상 환자군에서는 뇌손상이 과도한 stress로 작용하여 환자의 free cortisol 분비량과 circadian 리듬에도 영향을 주는 것으로 나타났다. 그러므로 뇌손상환자를 간호하는 간호사는 스트레스상태인 것을 인지하여 환자 개개인에 필요한 간호를 해야 할 것으로 사료된다.

• ETRI Journal
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• v.31 no.5
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• pp.481-488
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• 2009

This paper proposes a new multiuser scheduling algorithm that can simultaneously support a variety of different quality-of-service (QoS) user groups while satisfying fairness among users in the same QoS group in MIMO broadcast channels. Toward this goal, the proposed algorithm consists of two parts: a QoS-aware fair (QF) scheduling within a QoS group and an antenna trade-off scheme between different QoS groups. The proposed QF scheduling algorithm finds a user set from a certain QoS group which can satisfy the fairness among users in terms of throughput or delay. The antenna trade-off scheme can minimize the QoS violations of a higher priority user group by trading off the number of transmit antennas allocated to different QoS groups. Numerical results demonstrate that the proposed QF scheduling method satisfies different types of fairness among users and can adjust the degree of fairness among them. The antenna trade-off scheme combined with QF scheduling can improve the probability of QoS-guaranteed transmission when supporting different QoS groups.

• Bulletin of the Korean Chemical Society
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• v.32 no.5
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• pp.1640-1644
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• 2011

Water-soluble mutant of intrinsically insoluble protein, crambin, was produced by mutagenesis based on the sequence analysis with homologous proteins. Thr1, Phe13, and Lys33 of crambin were substituted for Lys, Tyr, and Lys, respectively. The resultant mutant was soluble in aqueous buffer as well as in dodecylphosphocholine (DPC) micelle solution. The $^1H-^{15}N$ spectrum of the mutant crambin showed spectral similarity to that of the wild-type protein except for local regions proximal to the sites of mutation. Solution structure of water-soluble mutant crambin was determined in aqueous buffer by NMR spectroscopy. The structure was almost identical to the wild-type structure determined in non-aqueous solvent. Subtle difference in structure was very local and related to the change of the intra- and inter-protein hydrophobic interaction of crambin. The structural details for the enhanced solubility of crambin in aqueous solvent by the mutation were provided and discussed.

• Journal of the Korean Chemical Society
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• v.20 no.3
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• pp.193-197
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• 1976

The ultrasonic absorption has been measured in aqueous solution of dodecyl pyridinium chloride (DPC) at $20^{\circ}C$ over the frequency range of 0.1${\sim}$90 Mc.The excess absorption was observed only in solutions in which the concentration was higher than the critical micellar concentration(cmc). The mechanism for this feature was attributed to the reaction $M_2\;{\rightleftharpoons}\;M_1\;＋\;1.2Cl^-$ Where $M_2$ and $M_1$ and M1 are two types of micelle. The rate constants of the forward and the reverse reactions were $6.6{\times}10^5 sec^{-1}\;and\;2.7{\times}10^11sec^{-1}mol^{-1.2}$respectively. Some kinetic charateristics including the free energy, enthalpy and entropy were calculated.