• Journal of the Korean Society for Precision Engineering
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• v.25 no.7
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• pp.7-12
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• 2008

• Biomedical Science Letters
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• v.21 no.2
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• pp.122-125
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• 2015

House dust mite (HDM) as a major allergen and damage-associated molecular pattern (DAMP) such as S100A8 and S100A9 trigger the pathogenesis and severity of allergic disease such as asthma. Regulation of neutrophil apoptosis is an important immune response and its dysregulation is involved in pathogenesis of allergic diseases. In this study, we examined the effects of HDM, S100A8 and S100A9 on spontaneous apoptosis of normal neutrophils. We considered the importance of the difference between in vitro and in vivo results and developed a new in vitro system consisting of a combination of immune cells and T helper (Th) cytokines. Extract of Dermatophagoides pteronyssinus (DP), S100A8, and S100A9 inhibited neutrophil apoptosis in culture of neutrophils alone without other leukocytes. DP and S100A8 more strongly suppressed neutrophil apoptosis in combinations of neutrophils, eosinophils, lymphocytes or monocytes than in a culture of neutrophils alone. Anti-apoptotic effect of S100A9 in the mixture of immune cells was similar to that in neutrophils. DP, S100A8, and S100A9 blocked neutrophil apoptosis, regardless of pretreatment with a T helper (Th) 1 cytokine (IFN-$\gamma$), Th2 cytokines (IL-4 and IL-10), a Th9 cytokine (IL-9), a Th17 cytokine (IL-17), a Treg-producing cytokine (TGF-$\beta$). These findings may enable elucidation of allergy pathogenesis due to HDM and DAMP.

• Analytical Science and Technology
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• v.30 no.6
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• pp.329-337
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• 2017

A major concern regarding most auto-repair shops in residential areas is the emission of odorous volatile organic compounds (VOCs) into the local atmosphere, especially during painting operations. VOCs contribute to poor local air quality and are responsible for the perceived odor and discomfort experienced by local residents. Sixteen major VOCs (6 aromatic hydrocarbons and 10 aliphatic carbonyl compounds) were selected as potential target compounds. The site was an auto-repair shop located in a central region of Seoul, South Korea, where the air quality of the site has been a subject of residents' complaints. The sampling points were as follows: 1) in the painting booth with new (NB) or old (OB) removal system, (2) in the exhaust duct after new (ND) or old (OD) odor removal filter, and (3) 2 m below the discharge vent (4 m above the ground) (outdoor air, OA). Each sample was coded: (1) before painting (BP), (2) during painting (DP), and (3) after painting (AP). The toluene level in the duct with the new removal filter during painting (ND-DP) was 1.5 ppm (v/v), while it was 3.8 ppm (v/v) in the right duct with an old removal filter during painting (OD-DP). Accordingly, the effect of filter replacement was reflected by differences in VOC levels. Therefore, accurate monitoring of odorous VOCs is an important step to reduce odor nuisance from local sources.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.8 no.2
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• pp.33-40
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• 2018

There are lots of literature about connected car system from industry and academia. The connected car is a smart car integrated with IT technology that is connected to people, vehicles and traffic management systems. It is important to V2I (vehicle to infrastructure) communication which is the connection between the vehicle and the infrastructure. CIM (cooperative intersection management) is a device to manage the communication between vehicle and infrastructure. In this paper, we analyze two intelligent vehicle control methods using CIM at non-signalized intersections. In the first method, a vehicle to pass through intersection needs to reserve a resource of intersection. In the second method, trajectory patterns on pre-planned vehicles are classified to pass through intersection. We analyze case studies of two methods to be implemented by DP(dynamic programming) and ACO(ant colony optimization) algorithms. The methods can be reasonably improved by placing importance on vehicles or controlling speeds of vehicles.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2001.06a
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• pp.233-239
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• 2001

최근 대부분의 회사들은 업무를 수행하는데 필요한 지식과 노하우를 공유하고 재사용하기 위하여 지적 자산 관리의 중요성을 인식하고 있다. 특히 고도로 지식 집약적인 업종이라 할 수 있는 IT컨설팅 회사에서는 지적 자산의 관리가 다른 어떤 회사에서보다 큰 중요성을 가지게 된다. 컨설팅 회사에 있어서 검증이 완료된 지적 자산의 공유 및 지능적이면서도 신속한 검색은 컨설팅 서비스의 품질과 고객 만족에 직결되는 중요한 요소이다. 따라서 대부분의 컨설팅 회사들은 자사의 지식 자산을 관리하기 위하여 많은 노력을 기울이고 있다. 본 논문의 목적은 IT 컨설팅 회사예서 관리되는 다양한 형태의 지적 자산들을 중앙 관리하여 설친 고객 사이트에 흩어져 프로젝트를 수행하는 컨설턴트들이 공유할 수 있도록 함으로써 컨설팅 서비스의 생산성과 품질들 높이고자 하는데 있다 이를 위하여 건설팅 회사에서 관리되는 모든 지적 자산의 재고를 조사하여 모델링하고 이를 쉽게 저장하고 검색할 수 있는 시스템 아키텍처를 제안한다. 제안된 아키텍처를 NT 기반에서 Index server를 이용하여 시스템으로 구현하였다 (KMSCR: A Knowledge Management System for managing Consulting Resources). KMSCR에서는 컨설턴트가 찾고자 하는 검색어를 입력하면 다양한 포맷의 (.doc, .ppt, xls, .rtf, .txt, .html 등과 같은) 결과물을 관련성이 높은 순서대로 출력해 줌으로써 컨설팅 리소스를 효과적으로 재사용할 수 있도록 도와 준다. 또한 검색 시에는 미리 등록된 키워드 뿐 아니라 본문 내의 텍스트 검색까지 가능하게 함으로써 컨설팅 리소스에 대한 보다 효과적이고 효율적인 검색을 가능하게 한다.간을 성능 평가 인자로 하여 수행하였다. 논문에서 제한된 방법을 적용한 개선된 RICH-DP을 모의 실험을 통하여 분석한 결과 기존의 제한된 RICH-DP는 실시간 서비스에 대한 처리율이 낮아지며 서비스 시간이 보장되지 못했다. 따라서 실시간 서비스에 대한 새로운 제안된 기법을 제안하고 성능 평가한 결과 기존의 RICH-DP보다 성능이 향상됨을 확인 할 수 있었다.(actual world)에서 가상 관성 세계(possible inertia would)로 변화시켜서, 완수동사의 종결점(ending point)을 현실세계에서 가상의 미래 세계로 움직이는 역할을 한다. 결과적으로, IMP는 완수동사의 닫힌 완료 관점을 현실세계에서는 열린 미완료 관점으로 변환시키되, 가상 관성 세계에서는 그대로 닫힌 관점으로 유지 시키는 효과를 가진다. 한국어와 영어의 관점 변환 구문의 차이는 각 언어의 지속부사구의 어휘 목록의 전제(presupposition)의 차이로 설명된다. 본 논문은 영어의 지속부사구는 논항의 하위간격This paper will describe the application based on this approach developed by the authors in the FLEX EXPRIT IV n$^{\circ}$EP29158 in the Work-package "Knowledge Extraction & Data mining"where the information captured from digital newspapers is extracted and reused in tourist information context.terpolation performance of CNN was relatively

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.6
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• pp.803-814
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• 2022

The Lao government is continuously developing hydro-power dams in addition to the existing eight power plants in the Nam Ngum River basin and is expanding the power capacity of the existing power plants to meet the expected increase in electricity demand. Accordingly, the Lao government has requested an update on the existing reservoir operating rule curve in order to run the power plants efficiently. To this end, this study reviewed the current independent operating system as well as the joint operating system in order to maximize the annual power generation produced by a power plant by using CSUDP, general-purpose dynamic programming (DP) software. The appropriate operating regulation curve forms (URC/LRC, MRC) were extracted from the DP results, and the annual power generations were simulated by inputting them as the basic operating data of the reservoir operation set of the HEC-ResSim program. By synthesizing the amount of the annual power generation simulated, the existing operation regulation curve, the operational performance, and the opinion of the field operator, the optimal reservoir operation regulation curves that maximize the annual power generation of the target power plant were developed. Results revealed that a system operating in conjunction with the reservoir produces about 2.5 % more power generation than an independent reservoir due to the synergistic effect of the connection.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.2
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• pp.32-40
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• 1989

Dynamic ship positioning(DP) system is used to keep the position and heading of a ship, or a floating platform, above a pre-selected site on the seabed by using thrusters. This paper presents a control system based on filtering technique and optimal control theory. The planar motions of a vessel are assumed to consist of low frequency(LF) component and high frequency(HF) one. The former is mainly due to thrusters, current, wind and second order wave forces, while the latter is mainly due to first order oscillatory component of the wave force. Furthermore position measurement signals include the noise. By means of self-tuning filter and Kalman filter techniques, LF motion estimates and HF ones are seperately achieved from the position measurements of the vessel. The estimated LF motions are used as input to the feedback loops. The total thruster power is minimized using the Linear Quadratic Gaussian control theory. The performance of the vessel with the DP system is investigated by computer simulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.718-724
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• 2017

Considerable efforts have been made to expand the boundaries of domestic offshore plant industries, which have focused on the construction of the structures, to the engineering field. On the other hand, time domain analysis, which is one of the most important areas in designing floating offshore plants, relies mainly on the information given by foreign companies. As an early design of the Dynamic Positioning System (DPS) is mostly conducted by several specialized companies, domestic ship builders need to spend time and money to reflect the analysis into the hull shape design. This paper presents the framework required to analyze time domain performance of floating type offshore structures, which are equipped with DPS. To easily perform time domain analysis, framework generates the required input data for the solver, and is modularized to test the control algorithm and performance of a certain DPS. The effectiveness of the developed framework was verified by a simulation with a model ship and the total time for the entire analysis work was reduced by 50% or more.

• Journal of Haehwa Medicine
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• v.20 no.1
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• pp.69-83
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• 2011

Objectives: This study aimed to investigate the effects of Amyda sinensis (AS) on allergic inflammation mechanism related atopy dermatitis. Methods: To investigate the effects of AS, We study inhibitory effect of AS on the levels of pro-inflammatory cytokines released from Raw264.7 cell stimulated with LPS (lipopolysaccaride), and EoL-1, THP-1, Jutkat cell stimulated with DP (Dermatophagoides pteronyssinus), and LPS indused acute inflammatory BALB/c mouse model. Result: AS reduced the levels of IL-$1{\beta}$ released from Raw264.7 cell stimulated with LPS at 20 ug/ml, 5 ug/ml concentration, and reduced the levels of IL-6 in a dose-dependent. AS significantly reduced the levels of MCP-1 released from EoL-1 cell stimulated with DP (Dermatophagoides pteronyssinus) at all the concentration, and significantly reduced the level of IL-8 at 0.1 ug/ml concentration. AS significantly reduced the levels of MCP-1 released from THP-1 cell stimulated with DP (Dermatophagoides pteronyssinus) at 1 ug/ml concentration, and reduced the level of IL-6 in a dose-dependent. AS significantly reduced the levels of IL-4 released from Jutkat cell stimulated with DP at all the concentration, and significantly reduced the level of IL-5 at 0.1 ug/ml. 1 ug/ml concentration,. and reduced the level of TNF-${\alpha}$ in a dose-dependent. AS significantly reduced the levels of TNF-${\alpha}$, IL-6, IL-$1{\beta}$, in LPS indused acute inflammatory BALB/c mouse model, in a dose-dependent. Conclusion: These result suggested that AS has suppressive effect on pro-inflammatory cytokines in various cell lines through the regulation of immune system. AS could be applied on the medicinal sources for treatment of immune abnormal diseases such as atopy dermatitis afterward.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.3
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• pp.24-34
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• 2005

The automobile seat must satisfy various safety regulations for the passenger's safety. In many design practices, each component is independently designed by concentrating on a single related regulation. However, since multiple regulations can be involved in a seat component, there may be design confliction among the various safety regulations. Therefore, a new design methodology is required to effectively design an automobile seat. The axiomatic approach is employed for considering multiple regulations. The Independence Axiom is used to define the overall flow of the seat design. Functional requirements (FRs) are defined by safety regulations and components of the seat are classified into groups which yield design Parameters (DPs). The classification is carried out to have independence in the FR-DP relationship. Components in a DP group are determined by using orthogonal away of the design of experiments (DOE). Numerical analyses are utilized to evaluate the safety levels by using a commercial software system for nonlinear transient finite element analysis.