• Title/Summary/Keyword: DNP

Search Result 249, Processing Time 0.029 seconds

Localization of Dendroaspis natriuretic peptide (DNP) in the rat salivary glands (흰쥐 타액선내에서의 DENDROASPIS NATRIURETIC PEPTIDE(DNP)의 분포)

  • Kim, Jae-Gon;Lee, Young-Soo;Baik, Byeong-Ju;Park, Byung-Keon
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.28 no.3
    • /
    • pp.447-463
    • /
    • 2001
  • Dendroaspis natriuretic peptide (DNP), a fourth member of the natriuretic peptide isolated from the venom of the Dendroaspis angusticeps snake, has been reported to be present in human plasma and atrial myocardium and caused vasorelaxation and diuresis in experimental animals. However, it is uncertain whether they are present in peripheral organs other than the heart and its further physiological roles also remains to be clarified. To assess the possible physiological role of DNP in the salivary glands, I investigated the localization of DNP peptide in the rat salivary glands by immunohistochemistry and the binding sites for radiolabelled DNP in the rat salivary glands and oral mucosa using in vitro autoradiography. DNP immunoreactivity was widely distributed in the submandibular, sublingual and parotid glands, particularly in the ducts such as the intercalated and striated ducts, where atrial natriuretic peptide (ANP) was colocalized in consecutive sections, but not in acini. High density $^{125}I-DNP$ binding sites were localized in the epithelia of the tongue and hard palate, while low density binding sites for $^{125}I-DNP$ were also distributed in the submandibular, sublingual, and parotid glands. In the hard palate and tongue, the precise location of this binding was revealed on the basal and parabasal cells of the epithelia by emulsion microautoradiography. These results suggest that DNP may not only have a role in the salivary glands but also play a role in the regulation of growth in the oral epithelium, particularly in the hard palate and tongue.

  • PDF

Effect of pH on the Degradation of 2, 4-Dinitrophenol in Sequencing Batch Reactor Process (연속회분식(連續回分式) 처리공정(處理工程)에 의한 2, 4-Dinitrophenol분해시(分解時) pH의 영향(影響))

  • Jo, Kwan-Hyung
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.12 no.1
    • /
    • pp.96-101
    • /
    • 1998
  • Substrate inhibition of 2,4-dinitrophenol (DNP) degradation was investigated using activated sludge which had been adapted to mineralize DNP. DNP is a metabolic uncoupler, preventing cells from making energy for growth and it has been suggested that pH may be important in mitigating effects of uncouplers. After acclimation of the activated sludge, the effect of pH on toxicity of DNP at high concentration (75 mg/L) was investigated, over a pH range of 5 to 9. DNP inhibition was found to be strongly dependent on mixed liquor pH. The DNP degradation rate was highest in the pH range of 6.95 to 7.84; at pH 5.94 degradation of 75 mg/L DNP was significantly inhibited; at pH < 5.77, DNP degradation was completely inhibited after approximately 30% of the DNP was degraded. By comparison, no significant effect of pH variation in the same range was seen on glucose uptake by the activated sludge culture.

  • PDF

Design of DNP Controller for Robust Control of Auto-Equipment Systems (자동화 설비시스템의 강인제어를 위한 DNP 제어기 설계)

  • 조현섭
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.13 no.2
    • /
    • pp.55-62
    • /
    • 1999
  • In order to perform a elaborate task like as assembly, manufacturing and so forth of components, tracking control on the trajectory of power coming in contact with a target as well as tracking control on the movement course trajectory of end-effector is indispensable. In this paper, to bring under robust ard accurate control of auto-equipnent systems which disturbance, parameter alteration of system, uncertainty ard so forth exist, neural network controller called dynamic neural processor(DNP) is designed. Also, the learning architecture to compute inverse kinematic coordinates transfonnations in the manirclator of auto-equipnent systems is developed ard the example that DNP can be used is explained The architocture and learning algorithm of the proposed dynamic neural network, the DNP, are described and computer simllations are provided to demonstrate the effectiveness of the proposed learning method using the DNP.he DNP.

  • PDF

A Method of Robust Stabilization of the Plants Using DNP (DNP을 이용한 플랜트의 강인 안정화 기법)

  • Cho, Hyun-Seob
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.9 no.6
    • /
    • pp.1574-1580
    • /
    • 2008
  • In this paper, to bring under robust and accurate control of auto-equipment systems which disturbance, parameter alteration of system, uncertainty and so forth exist, neural network controller called dynamic neural processor(DNP) is designed In order to perform a elaborate task like as assembly, manufacturing and so forth of components, tracking control on the trajectory of power coming in contact with a target as well as tracking control on the movement course trajectory of end-effector is indispensable. Also, the learning architecture to compute inverse kinematic coordinates transformations in the Plants of auto-equipment systems is developed and the example that DNP can be used is explained. The architecture and learning algorithm of the proposed dynamic neural network, the DNP, are described and computer simulations are provided to demonstrate the effectiveness of the proposed learning method using the DNP.

Optimal design of DNP 3.0 network for the Distribution Automation System (배전자동화통신망을 위한 DNP 3.0 최적 설계 방안)

  • Kim, Tae-Gyeong
    • Proceedings of the KIEE Conference
    • /
    • 2009.07a
    • /
    • pp.422_423
    • /
    • 2009
  • DNP 3.0 is the most widely used data communication protocol for electric power control systems. KEPCO(Korea Electric Power Corporation) also uses DNP 3.0 as a data transmission protocol for the DAS(Distribution Automation System) and the SCADA system of the transmmission system. But DNP 3.0 is one of the oldest industrial standard having many restrictions and there are many considerations for optimal design of DNP 3.0 network for the Distribution Automation System.

  • PDF

HISTAMINE RELEASE INDUCED BY DENDROASPIS NATRIURETIC PEPTIDE FROM RAT PERITONEAL MAST CELLS (흰쥐 복강 비만세포에서 Dendroaspis natriuretic peptide에 의한 히스타민 유리)

  • Kim, Jae-Gon;Hur, Sun;Baik, Byeoung-Ju
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.28 no.1
    • /
    • pp.72-81
    • /
    • 2001
  • Dendroaspis natriuretic peptide (DNP), recently isolated from the venom of the green Mamba snake Dendroaspis angusticeps, is a 38-amino acid peptide containing a 17-amino acid disulfide ring structure similar to that of the natriuretic peptide family. The natriuretic peptide family was known to induce histamine release from human and rat mast cells, but there are no published data concerning the effects of DNP on histamine release from mast cells. The purpose of this study is to investigate whether DNP induces the histamine release from rat peritoneal mast cells (RMPCs) and to determine the mechanism of DNP-induced histamine release from RPMCs. After treatment of the various doses of DNP in RPMCs, the mast cell degranulation was observed with inverted microscopy and the histamine release was measured by radio-enzymatic assay. Calcium uptake and intracellular cyclic GMP level were measured by radioimmunoassays. DNP induced the mast cell degranulation. DNP released the histamine and increased the calcium uptake and the level of intracellular cyclic GMP of RPMCs, in a dose-dependent manner. The results indicate that DNP is capable of inducing histamine release from RPMCs by increasing of calcium uptake and intracellular cyclic GMP level.

  • PDF

Design of the Gateway Function for DNP3.0 and IEC61850 (DNP 3.0과 IEC 61850 게이트웨이 기능 설계)

  • Song, Byung-Kwen;Kim, Geon-Ung
    • Journal of IKEEE
    • /
    • v.12 no.3
    • /
    • pp.151-157
    • /
    • 2008
  • The DNP3.0 and the IEC61850 are the most important standards in the SCADA systems for the power. Each standard has strength and weakness, so they will coexist for a while. This paper presents a design of the gateway function between DNP3.0 and IEC61850. Both standards use object-oriented modelling methods, so, they have some similarities. However, the DNP3.0 objects are described by object number and index, and the IEC61850 objects are described by name. So there should be mapping function between the object number and index of DNP3.0 objects and the object name of IEC61850 objects. We analyse the communication profiles of both standards, and shows the service-primitive mapping table and the procedure of the gateway function.

  • PDF

Proposal and Implementation on Non-Repudiation of Origin for DNP3 (DNP3에 적합한 발신 부인 방지 기법 제안과 그 구현)

  • Yu, Ki-Soon;Song, Kyoung-Young;Jang, Min-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.40 no.5
    • /
    • pp.815-825
    • /
    • 2015
  • DNP3(Distributed Network Protocol) is one of the most representative protocols which is used in SCADA(Supervisory Control and Data Acquisition) system. IEC 62351 is listing the integrity, confidentiality, availability and non-repudiation or accountability as the security requirement. However, IEEE Std. 1815 that is DNP3 standards does not define a mechanism for non-repudiation or accountability. In this paper, we propose a non-repudiation of origin technique about the sender of critical ASDU and implement the proposed scheme using software such as OpenSSL and SCADA source code library.

Development of DNP API for simply applying to power IED (전력 IED에 간단하게 DNP 탑재를 위한 효율적 DNP API 개발)

  • Lim, Hee-Taek;Choi, Myeon-Song;Kim, Tea-Wan;Lee, Seung-Jae;Rim, Sung-Jung
    • Proceedings of the KIEE Conference
    • /
    • 2008.11a
    • /
    • pp.211-213
    • /
    • 2008
  • 현재의 전력산업에서 통신은 필수 항목이 되었다. 따라서 전력장치의 대부분이 통신 기능을 가지고 있으며 전력장치 개발을 위해서는 통신 탑재가 필수이다. 본 논문에서는 전력분야에서 가장 널리 사용되고 있는 DNP(Distributed Network Protocol)를 간편하게 전력장치에 탑재할 수 있는 DNP 이길를 제안한다. 제안된 DNP API는 Recloser에 DNP를 탑재하여 편리성을 검증하고, Test Harness를 통하여 통신 신뢰도를 검증하였다.

  • PDF

Role of Sodium lon in Biodegradation of Nitroaromatic Compound by Activated Sludge and Pure Cultures

  • Jo, Kwan-Hyung
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
    • /
    • v.3 no.3
    • /
    • pp.169-175
    • /
    • 1999
  • 2,4-Dinitrophenol(DNP) is a metabolic uncoupler that prevents cells from creating energy for growth and it has been suggested that the availability of sodium ions may be important in mitigating the effects of uncouplers. Accordingly, the degradation of DNP was investigated using activated sludge which had been adapted to mineralize DNP. After the acclimation of the activated sludge, the effect of sodium ions on the toxicity of high concentrations(80 to 100mg/L) of DNP was investigated over a sodium ion concentration range of 9.3$\times$10-5 to 94mM. The concentration of sodium ions in the activated sludge mixed liquor seemed to have little effect on the DNP toxicity. However, a lack of sodium in the grwoth media resulted in a reduction of the DNP degradation rate by a bacterial isolate from the activated sludge culture identified as Nocardia asteroides.

  • PDF