• Proceedings of the IEEK Conference
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• 1998.10a
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• pp.825-828
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• 1998

경혈을 대상으로 인체를 진단하는 의료기기들은 경혈점에 미세한 직류전류를 인가하고, 이 점에서의 전기저항과 세포의 분극에 의해 반응하는 경락체계의 균형상태를 측정하여 인체를 종합적으로 진단한다. 따라서 전 과정이 정확한 경혈의 위치에서 이루어져야만 치료효과와 진단의 신뢰성이 보장된다. 그러나 대부분의 경락관련 치료기들이 정확한 혈위식별에 어려움이 있고 사용자의 전문적 숙련을 요구한다. 따라서 선행연구에서 일정한 주파수로 교호되는 자극패턴(SPAC) 방식을 사용하여 식별률을 높인 혈위식별기 DM96A-1를 개발하였다. DM96A-1은 단일전원이 양방향으로 교호되는 전류로 자극펄스를 출력하고 측정범위가 0.5∼50㎂인 전류메터와 레벨메터를 이용하여 혈위의 전류량을 표시한다. 이에 따라 방향전환 소자의 두 채널 제어신호가 교호되는 과도기에서 두 자극패턴의 중첩 도통에 의해서 누설전류가 발생하는 경우가 있으며 이를 제거하기 위하여 정밀한 조정을 필요로 하는 불편이 있었다. 따라서 이와 같은 단점들을 보완하여 신뢰성 있는 출력 파라메터를 얻을 수 있도록 마이크로프로세서 i80c196kc를 사용하여 DM96A-2를 재 설계하였으며 임상실험에 의하여 개선된 최적 파라메터의 타당성을 검증하였다.

• Journal of The Korean Society of Grassland and Forage Science
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• v.9 no.3
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• pp.129-134
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• 1989

This experiment was conducted to evaluate the effect of cutting frequency and nitrogen fertilization on th change of vegetation and the yield of dry matter on the different mixture combination of permanent pasture. 1. DM yield was increased as the increasing Arrhenatherum elntius but was decreased as the increasing Tkisetum fkavescens. 2. DM yield was unaffectdd by the different mixture combination of permanent pasture eventually. 3. In case of cutting frequency, 2-cutting showed higher DM yield than that of 3-cutting, and N-fertilization level showed significant increase in DM yield as the increasing N-level, especially 2-cutting block of N-3 showed the highest yield and 3-cutting block of N-l showed the lowest yield. 4. Mixture combination, N-level and cutting frequency did not show significant changes in DM yield of permanent pasture eventually.

• Journal of the Korean Magnetics Society
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• v.17 no.5
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• pp.215-220
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• 2007

The superexchange interaction is introduced to explain antiferromagnetic ordering in transition metal compounds such as MnO and $MnF_2$. The anisotropic superexchange (Dzyaloshinskii-Moriya: DM) interaction can be derived by incorporating the spin-orbit interaction into the superexchange interaction. The anisotropic superexchange DM can account for the weak ferromagnetism observed in transition metal compounds such as ${\alpha}-Fe_2O_3$, $MnCO_3$, $CrF_3$.

• Diabetes and Metabolism Journal
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• v.42 no.6
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• pp.451-464
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• 2018

Latent autoimmune diabetes in adults (LADA) is a heterogeneous disease characterized by a less intensive autoimmune process and a broad clinical phenotype compared to classical type 1 diabetes mellitus (T1DM), sharing features with both type 2 diabetes mellitus (T2DM) and T1DM. Since patients affected by LADA are initially insulin independent and recognizable only by testing for islet-cell autoantibodies, it could be difficult to identify LADA in clinical setting and a high misdiagnosis rate still remains among patients with T2DM. Ideally, islet-cell autoantibodies screening should be performed in subjects with newly diagnosed T2DM, ensuring a closer monitoring of those resulted positive and avoiding treatment of hyperglycaemia which might increase the rate of ${\beta}-cells$ loss. Thus, since the autoimmune process in LADA seems to be slower than in classical T1DM, there is a wider window for new therapeutic interventions that may slow down ${\beta}-cell$ failure. This review summarizes the current understanding of LADA, by evaluating data from most recent studies, the actual gaps in diagnosis and management. Finally, we critically highlight and discuss novel findings and future perspectives on the therapeutic approach in LADA.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.6 no.2
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• pp.255-266
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• 1999

This study was done to analyze the effects of a smear in the nasal cavity against nosocomial Infection. The smear used was mupirocin, and the study centered on infection which constitutes the majority of nosocomial infections called MRSA. The data were collected between March 23 1998 and June 31 of the same year in a university hospital in the Kyongi Province, and is made up of a experimental group of 14 patients who were given nasal cavity smears and a control group of 16 patients who were not given nasal cavity smears. The data were analyzed through frequency and the Chi-square tests and gave forth these results. 1. Of the experimental group 28.6% developed nosocomial infections while 62.5% of the control group developed infections. This difference was significant. 2. In the experimental group, all of the patients developed infections within the first week in the ICU, while 80% of the control group developed infections in the first week and 20% in the second week. The difference was not as marked here. 3. In the experimental group the DM group 66.7% contracted MRSA while 18.2% developed it in the non-DM group showing that the DM group had infection rate was 3.7 times higher than the non-DM groups. In the control group the DM group had a 100% infection rate while 50% of the non-DM group developed it. Overall the DM group's rate infection was 2.4 times higher than the non-DM group. 4. In the experimental group, 37.55% of the patients who had a tracheostomy developed it while 16.7% of the patients who did not have a tracheostomy developed infections. In the control group, 62.5% of the patients who had tracheostomy, and 37.5% of the patients who did not have tracheostomies developed infections. Those who had tracheostomies, and the control group had double the rate contracting infections. From these results we can see that nasal cavity smears are effective against nosocomial infections. In spite of the smears, patients with the diabetes mellitus had a high MRSA infection rate, which requires new alternative treatments.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5675-5680
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• 2013

Background: Preexisting type 2 diabetes mellitus (T2DM) affects the prognosis and mortality of patients with some cancers. Insulin like growth factor (IGF) and insulin receptor (IR) signaling axes play important roles in both cancer and diabetes development. We aimed to explore the expression characteristics of proteins in IGF/IR axis in non-small cell lung cancer (NSCLC) cases with preexisting T2DM. Methods: Fifty-five NSCLC patients with preexisting T2DM were retrospectively included and matched by 55 NSCLC without diabetes at a 1:1 ratio. The expression of proteins in IGF/IR axis was detected by immunohistochemical staining. Clinicopathological data were collected to analyze their relationship with the protein expression. Results: Both IGF 1 receptor (IGF-1R) and insulin receptor substrate 2 (IRS-2) showed higher expression in the NSCLC with T2DM group, compared with those without T2DM. The high expression of IGF-1R and IRS-2 were found to be negatively associated with lymph node metastases and T staging in the T2DM group, respectively, and IRS-2 expression was also found more in the subgroup whose T2DM duration was more than 4 years. No difference was detected in the expression of IRS-1, IGF-1, IGF-2, IGFBP3, IR and mTOR between groups with or without T2DM. Conclusion: Our study found higher expression of IGF-1R and IRS-2 proteins in NSCLC patients with preexisting T2DM, and that there was an association with early stage NSCLC, which suggested that IGF signaling may play an important early event in development of NSCLC associated with diabetes.

• Korean Journal of Microbiology
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• v.55 no.3
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• pp.293-295
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• 2019

Enterococcus faecalis strain DM01 was isolated from meju, a traditional Korean fermented soybean product. The strain did not exhibit resistance to eight antibiotics (ampicillin, chloramphenicol, ciprofloxacin, erythromycin, gentamicin, penicillin G, tetracycline, and vancomycin), biofilm formation, and hemolytic activity. The genome of strain DM01 consists a single circular 2,785,968-bp chromosome with a G + C content of 37.68%. The complete genomic sequence of strain DM01 provides genetic information to support the absence of antibiotic resistance, biofilm formation, and hemolytic activity.

• Journal of East-West Nursing Research
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• v.1 no.1
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• pp.72-81
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• 1997

Korean society is a mix of western and traditional cultures. Even though the patients try to recover through both aspects, hospital only utilizes a western approachs. When they have suffered from a chronic disease, especially diabeties meliitus(DM), application of folk medicine is more varied but the nurses are unaware of the practices. This study was done to describe the current use of the folk medicine with which the patients with DM have had an experience and to identify the relationships between the westernized medical care and folk medicine application. The 244 patients with non-insulin dependent diabetes millitus who participated were interviewed at a DM education clinic in a 1500-bed hospital. The results of the study are as follows: 1. 54.1%(N=133) of the participated patients in this study have had a folk medicine. 2. 44 kinds of folk medicine were used for the treatment of DM. Among them 14 items were used by more than two people and the rest were used by one person. Among the used items, 70.4% consisted of various types of plants, 11.4% was animal material and 18. 2% was the mixed group. As a single item, Commelina Communis(Dalgaebi) was the most frequently used(62.8%), followed by the root of Rosa rugosa(Haedangwha) 14.3%, and Youngi mushroom 13.6%. 3. In the analysis of the relationships between the general characters of the patients with regular fol1ow-up(F-U), self blood sugar test(BST) and folk medicine usage: 1) The higher the educational back ground patient had, the lower the folk medicine usage was ($X^2$=14.265, P=.003). 2) The more complex their treatment was($X^2$=24. 016. P=.000). and the longer they had suffered from DM($X^2$=75.739, P=.000), the fewer they visited regular F-U. On the other hand, they did self-BST well($X^2$=7.722, P=.021 : $X^2$=14. 775, P=.002) and had more folk medicine($X^2$=33.382, P=.000 ; $X^2$=43.410, P=.000). 3) If they had suffered many symptoms, they had fewer regular F-U ($X^2$=13.192. P=.001). On the other hand, they had more folk medicine($X^2$=6.070, P=.048). 4) The group of family history($X^2$=6.801. P=.009) and the group of DM education experience($X^2$=15.678, P=.000) carried out self BST well. DM education group used more folk medicine($X^2$=8.680, P=.003). In conclusion, DM education should be grouped according to the treatment type and suffering period. Then the management of DM would be effective and the vague application of folk medicine would be decreased.

• Korean Journal of Head & Neck Oncology
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• v.31 no.2
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• pp.11-15
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• 2015

Background and Objectives: This study aimed to analyze the features of patients with papillary thyroid carcinoma (PTC) recurred as distant metastases (DM). Materials and Method: We retrospectively reviewed and analyzed clinical records of 63 patients who were treated for PTC recurred as DM between 2000 and 2006. Univariate and multivariate analyses of various clinical factors were performed. Results: Male patients were 12, and female patients were 51. The 5- and 10-year survival rates for PTC recurred as DM were 85% and 73%, respectively. Size of tumor, multiplicity of tumor, lateral neck node metastasis, and RAI ablation therapy with other treatments such as surgery were associated with survival rate (p < 0.005) in univariate analysis. The lateral neck node metastasis[p =0.039, hazard ratio=2.2(95% CI. 1.18~3.24)] and multiple organ DM[p =0.041, hazard ratio=2.18(95% CI. 1.03~2.89)] were related to the survival in multivariate analysis. Conclusion: PTC recurred as DM is uncommon (2.2%). The size of tumor, the multiplicity of tumor, lateral neck node metastasis and RAI ablation therapy with other treatments for DM were revealed as associated factors for the survival. Evaluation of DM should be considered in patients with PTC during long-term follow-up.

• Journal of The Korean Society of Grassland and Forage Science
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• v.5 no.1
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• pp.84-89
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• 1985

Chemical composition, dry matter and cellulose digestibilities and fermentation rates of alfalfa and orchard grass cut at different time were estimated in vitro method and the results summurized as follows: 1. Crude protein, crude fiber cwc and cellulose content of Alfalfa were decreassed as advancing cutting time. Crude protein, crude fiber and cwc content of Orchard grass were decreased as advancing cutting time up to 3 cutting, but crude protein was slightly increased at 4th cutting, crude fiber and cellulose content were higher at 2nd cutting, but decreased thereafter. 2. DM digestibility of Alfalfa was 51.80, 51.86, 52.92 and 59.52% at 1, 2, 3 and 4th cutting time, respectibly, thus slightly increased as advancing cutting time, and cellulose digestibility of Alfalfa was not much different with different cutting time. DM digestibility of Orchard grass was 62.21, 66.10, 60.95 and 66.32% at 1, 2, 3 and 4th cutting time, respectibly, and cellulose digestibility of Orchard grass was slightly increased at 3rd cutting time and then increased at 4th cutting time. 3. Fermentation rate of DM of alfalfa was the highest 1st cutting time (0.83%/hr.) and was not different at 3 and 4th cutting time. Cellulose fermentation rate of Alfalfa was the highest at 1st cutting time (1.29%/hr.), decreased at 2 and 3th and then increased at 4th cutting time. Fermentation rate of DM of Orchard grass was 1.42, 1.58, 1.60 and 1.57%/hr. and of cellulose was the highest at 2nd cutting time (1.77%/hr.)