• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.127-134
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• 2001

Objective : In this study, we have discovered that Korean Bee-Venom therapy is effective in treating various hip joint diseases. For example, A vacular Necrosis, Degenerative Arthritis and Rheumatoid Arthritis. Methods & Results: We have treated three cases of affections of the hip(eg. Degenerative arthritis, Rheumatoid arthritis and Avascular Necrosis of Femoral Head) with Korean Bee-Venom therapy and herbal acupuncture treatments. For acupuncture, Korean Bee-Venom therapy was observed for its pain relieving effects. Korean Bee-Venom therapy was treated on the following acupuncture points: GB29(Koryo), GB30(Hwando:環跳), ST36(Chok-samni:足三理). As the results of these treatments, a little change of inflammation around the hip joint on X-ray scan study was observed. but the degree of pain and range of motion were improved. in addition to general conditions of the patients. Conclusions: Based on the clinical results, Korean Bee-Venom therapy is believed to be effective for treating Avascular Necrosis of Femoral Head, Degenerative arthritis and Rheumatoid arthritis of hip joint. However, it is expected that further studies should be conducted to provide more objective information.

• Journal of Veterinary Clinics
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• v.8 no.1
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• pp.11-26
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• 1991

The effects of intra-articula. sodium hyaluronate(SH) and polysulfated glycosaminoglycan(PSGAG) on degenerative joint disease of the carpus were compared each other In 20 racehorses. Ten horses were dosed with intra-articula. injection of 20mg SH(2 times/2 weeks interval) and ten horses were dosed with intra-articular injection of 250mg of PSGAG(4 times/1 week into.val). Synovial fluid analysis and clinical examination were made to evaluate the effects of the drugs on degenerative joint disease at before injection and 2 weeks after the last injection, respectively. Appearance and mucinous precipitate quality oi synovial fluids of the group injected with 58 and PSGAG were improved by 40～50% and 60～80%, respectively. The chemical values of alkaline phosphatase, lactic dehydrogenase, aspartate aminotransferase, total protein, A/G ratio and glucose of synovial fluid in the group injected with PSGAG were more clearly returned to the normal values than those of the group injected with SH. Relative viscosity and total white blood cells of synovial fluid were returned to the normal walues after the treatments in both groups. Clinical symptoms(swelling, heat and pain on carpal joint, and lameness) of the horses in the group injected with SH and PSGAG were disappeard by 56～67% and 67～80%, respectivelty. Conclusively, the PSGAG was superior to SH in the effects on treatment of the degenerative joint disease in the horses.

• Journal of Acupuncture Research
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• v.21 no.4
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• pp.65-73
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• 2004

Objective: This study was designed to compared the effect of general acupuncture on degenerative arthritis of knee joint with 8 constitution acupuncture by Visual Analogue Scale(VAS). Methods: VAS was used for this research, with the pain indicator of 10 and 0 which represents a pain of first visit and a status of no pain respectively. Two groups, consisting of 40 patients, was randomly allocated for this research. SPSS(Statistic Program for Social Science) 10.0 for window was used for a statistical analysis. Independent T-test and Mann Whitney U test was performed to evaluate the improvement of each group by the treatment number and to compare that of two groups. Results: As a result of the comparison analysis between two groups after 20th treatment, the improvement of subjective symptoms in 8 constitution acupuncture group was shown more effective than that in general acupuncture group, while, After 10th treatment, there was no significant difference between two groups in VAS. Conclusion: It is suggested that the effect of 8 constitution acupuncture should be significantly different from that of general acupuncture on degenerative arthritis of knee joint. Further study is needed to confirm the effectiveness of 8 constitution acupuncture.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1963-1966
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• 2005

Degenerative lumbar spinal stenosis(DLSS) is a disease inducing low back pain, leg pain, convulsion, numbness, and neurogenic claudication from compression of nerve root. Intervertebra fixation was reported to increase the degenerative of neighbor region after treatment. Recently, a new surgical technique of inserting a fixator between interspinous processes has been introduced. The purpose of this study is to design of the interspinous process fixator with flexibility to complement the trouble of using fixator in DLSS. This study evaluated the existing fixator through the mechanical test and modified fixators using the finite element analysis(FEA). Displacement, stiffness and Von-Mises stress were found to have similar values to those obtained from the mechanical test and the FEA in the biomechanical loading condition. Effects of variation in length and thickness were investigated to design an optimal fixator.

• Journal of Korean Neurosurgical Society
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• v.58 no.5
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• pp.401-411
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• 2015

More than 10 years have passed since lumbar total disc replacement (LTDR) was introduced for the first time to the world market for the surgical management of lumbar degenerative disc disease (DDD). It seems like the right time to sum up the relevant results in order to understand where LTDR stands on now, and is heading forward to. The pathogenesis of DDD has been currently settled, but diagnosis and managements are still controversial. Fusion is recognized as golden standard of surgical managements but has various kinds of shortcomings. Lately, LTDR has been expected to replace fusion surgery. A great deal of LTDR reports has come out. Among them, more than 5-year follow-up prospective randomized controlled studies including USA IDE trials were expected to elucidate whether for LTDR to have therapeutic benefit compared to fusion. The results of these studies revealed that LTDR was not inferior to fusion. Most of clinical studies dealing with LTDR revealed that there was no strong evidence for preventive effect of LTDR against symptomatic degenerative changes of adjacent segment disease. LTDR does not have shortcomings associated with fusion. However, it has a potentiality of the new complications to occur, which surgeons have never experienced in fusion surgeries. Consequently, longer follow-up should be necessary as yet to confirm the maintenance of improved surgical outcome and to observe any very late complications. LTDR still may get a chance to establish itself as a substitute of fusion both nominally and virtually if it eases the concerns listed above.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.3
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• pp.203-213
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• 2006

Purpose : This study was carried out to evaluate correlation between Bone Mineral Density(BMD) and degenerative lumbar disease in postmenopausal low back pain patients. Methods : 69 postmenopausal patients with low back pain were examined. Magnetic resonance imaging was performed to evaluate degenerative lumbar disease and bone mineral density of lumbar spine was measured by Dual energy X-ray absorptiometry. Data were analyzed by Pearson's Linear Correlation Coefficient. Results : In postmenopausal patients with low back pain, BMD(T-score, Z-score) had negative correlation with the grade of intervertebral disc herniation and positive correlation with weight. Other lumbar diseases including Spinal stenosis, Spondylolisthesis and Facet joint arthrosis didn't have significant correlation with BMD. Conclusion : In postmenopausal patients with low back pain, BMD(T-score, Z-score) had inverse relationship with the grade of intervertebral disc herniation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.10
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• pp.4411-4417
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• 2011

Degenerative brain diseases including Alzheimer's diseases, Parkinson's diseases increase in frequency with age. They are amongst the most costly and devastating diseases to patients and their families. Therefore developing therapies for degenerative brain diseases is of the highest priority. Recently therapeutics for these diseases have undergone scrutiny by many clinical trials according to the advances of cellular and molecular neurobiology. This review is focused on studies investigating the current therapeutic strategies already undergone different stage of clinical trials and recent R&D trend by nations through patent analysis on treatments for degegerative brain diseases.

• Journal of Society of Preventive Korean Medicine
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• v.13 no.1
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• pp.81-92
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• 2009

Objective : This study was designed to the effect of moxibustion therapy on the pain decrease and joint recovery with degenerative knee arthritis Methods : The research was administered from January to March 2008. The study subjects are menopause female 20 person and over 50 years old with degenerative knee arthritis patients, The Research were conducted with 10 moxibustion group and to 10 hot pack group during 4 Weeks. Results : 1. There is no significant difference of LSS of pre-treatment between hot pack group and moxibustion group(p<0.05). 2. There is no significant difference of LSS of post-treatment between hot pack group and moxibustion group(p<0.05). 3. There is no significant difference of LSS between pretreatment and post-treatment in hot pack group and moxibustion group(p<0.05). 4. There is no significant difference of VAS of pre-treatment between hot pack group and moxibustion group(p<0.05). Conclusion : This study suggests that hot pack used usually in physical therapy can decrease pain but the there is no significantly different between these two methods.

• Korean Journal of Applied Biomechanics
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• v.32 no.4
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• pp.141-146
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• 2022

Objective: The purpose of this study was to investigate the effects of different frequency on muscle function of the thigh in patients with degenerative knee arthritis during the functional electrical stimulation (FES). Method: For this study, 16 male participants over 65 who patients with degenerative knee arthritis were recruited as research participants. In this research, isokinetic muscular function, EMG, and joint position sensation were performed after FES treatment was applied for three conditions (FES 20, FES 50, and Without FES). For each dependent variable, one-way ANOVA with repeated measures was to determine whether there were significant differences among three different conditions (p<.05). When a significant difference was found, post hoc analyses were performed by using the contrast procedure. Results: When compared to FES 50 and without FES, FES 20 causes significant increase in isometric knee extension strength. No significant differences were found in EMG values across different EMS conditions. Conclusion: The present study examined isokinetic muscular function, EMG, and joint position sensation in order to investigate the effects of different frequency muscle function of knee extensors during the functional electrical stimulation. The results of this study showed that FES with 20 Hz frequency had positive effect on knee extensor. Based on the findings of the present study, FES with lower frequency may help the performer to focus on developing strength in knee extensor muscles.

• Journal of Acupuncture Research
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• v.18 no.3
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• pp.215-226
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• 2001

Objective : Spondylolisthesis has become one of the major causes of the lower back pain in the orthopedic field. We wanted to compare the radiological change with before & after treatment including constitution-acupuncture on spondylolisthesis. Methods : This study were carried out on 9 patients with spondylolisthesis. We reviewed medical records and radiological films. We studied rating score, percent of slip, sagittal angle, percent of posterior disc height. Results and conclusions : The improvement index showed 0.04, 030, 033, 0.00, 0.32 points in isthmic type, and 0.55, 0.56, 0.53, 0.00 points in degenerative type. The percent of slip for pre/post-treatment showed 20/20, 12/11, 24/20, 30/30, 4/3 percents in isthmic type, and 12/4, 16/11, 13/9, 8/8 percents in degenerative type. Sagittal angle showed 11/11, 15/12, 21/18, 17/15, 21.19 degrees in isthmic type, and 22/21, 19/15, 2/2, 8/9 degrees in degenerative type. Percent of posterior disc height were 17/18, 26/28, 24/25, 22/23, 25/27 in isthmic type, and 29/33, 37/45, 25/31, 24/24 in degenerative type. The result suggest that constitution-acupuncture and conservational treatment are good method for treatment of spondylolisthesis, and especially in degenerative type.