• MALSORI
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• no.58
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• pp.1-18
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• 2006

The purpose of this study was to investigate diadochokinetic (DDK) characteristics in the subjects with spastic cerebral palsy (CP) by severity. DDK characteristics were measured through rate, regularity, accuracy and consistency in Alternate Motion rate (AMR) and Sequential Motion rate (SMR) tasks. The subjects participated in this study included 27 subjects with spastic CP (mild- 9, moderate- 9, severe- 9) and 9 normal persons who are around 11-20 years old. On the result of this study, rate in AMR was significant difference between all spastic groups and normal group, and rate in SMR was significant difference between normal and mild groups and moderate and severe groups. In regularity of the DDK tasks, severe group had significant difference the other groups. Finally, accuracy and consistency of the DDK tasks exhibited significant difference between all spastic groups and normal group. In conclusion, the subjects with spastic CP have a tendency to produce slow and irregular syllable repetition as severity increases, but to produce inaccurate and inconsistent syllable repetition regardless of severity in the DDK tasks.

• Phonetics and Speech Sciences
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• v.5 no.3
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• pp.95-101
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• 2013

Aging is related to anatomical and physiological changes in respiratory and phonation organs. These changes influence articulation which leads to inaccurate speech and slow articulatory diadochokinesis(DDK). DDK indicates the range, rate, regularity, accuracy, and agility of articulation that reflect motor speech function. The purpose of this study is to investigate the rates and regularities of DDK in healthy Korean elderly through passive acoustic analysis (Praat). Thirty subjects between the ages of 65 and 94 participated in this study. Rate was observed for 5 seconds, while regularity was calculated based on the standard deviation on the following: 1) syllable duration of each task; 2) gap duration between syllables. Then, simple regression analysis was conducted in order to examine the effect of age on performance. The result showed that the slow rate was not a significant factor in terms of advancing age. Furthermore, regularity indicated a significant difference in the following: 1) /pʌ/, /kʌ/ and /pʌtʌkʌ/ in syllable duration; 2) /kʌ/ duration in the gap between syllables. In conclusion, articulatory coordination is reduced with the onset of aging. In particular, /kʌ/ would be a sensitive task for articulatory coordination.

• Phonetics and Speech Sciences
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• v.9 no.2
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• pp.125-135
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• 2017

The current study examines PCC (percentage of correct consonant), speech intelligibility, and oral motor function between the group of typically developing children and the group of children with Down's syndrome. To 15 children with Down's syndrome (mean CA: 9;7) and 15 typically developing children on receptive language age, the following tests were administered: K-WPPSI (2001), Picture Vocabulary Test (Kim et al., 1995), Oral and Speech Motor Control Protocol for total oral functional score (Robbins et al., 1987), DDK and Assessment of Phonology and Articulation for Children (APAC, Kim et al., 2007) for PCC and speech intelligibility. Pearson correlation coefficients were computed for the total oral functional score, PCC and DDK of each group. The statistical analysis showed that there is no significant difference in total functional score and DDK when IQ was controlled. There was a significant correlation between total oral functional score and PCC in the Down's syndrome group and a significant correlation between total oral functional score and intelligibility in the Down's syndrome group whether IQ was controlled or not. The findings suggest that both cognitive ability and overall oral motor function need to be considered for the intervention to enhance PCC or speech intelligibility of children with Down's syndrome.

• Phonetics and Speech Sciences
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• v.6 no.3
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• pp.3-12
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• 2014

Larynx plays an important role in phonation and protection of the respiratory tract during swallowing. The reduced anatomical and physiological function in elevation of larynx and glottis closure can cause problems in voice and swallowing. The present study investigated the Korean version of handicap index of dysphagia in elderly Koreans. Therefore, 60 normal elderly Koreans ranged from 65 to 95 and 20 normal Korean young adults aged from 20 to 25 were participated in this study to compare total (T), physical (P), functional (F), and emotional (E) index scores between two groups as well as among sub groups (60s, 70s, 80s) in elderly. For swallowing, total and sub dysphagia handicap index (DHI) scores, voice quality during /a/phonation following swallowing (saliva and water), intensity of coughing, and L-DDK were measured. The results showed that functional (P), physical (P), emotional (E) scores as well as total (T) score were significantly different between young adults and old adults in DHI(p<.05). Additionally, there was a negative correlation between total DHI score and intensity of coughing (r=-.51) as well as L-DDK (r=-.70). These findings suggest that a slow rate in vocal fold adduction and reduced intensity of coughing in the elderly affect swallowing function. Thus, recently translated Korean version of DHI may be useful as supplement in evaluating the swallowing problems in elderly people.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.85-85
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• 2002

Pregnancy block by male pheromones in mice differs in incidence depending on the combination of strains. Female mice of BALB/cA strain mated with BALB/cA males show a 100% pregnancy block when exposed to males of inbred strain DDK shortly after copulation (Chung et al., Biol Reprod 1997). In the present study, BALB/cA females mated with the males of other strains (CBA/J, C3H/HeN, C57BL/6Cr, and IXBL) showed higher pregnancy rates (66.6-87.5%) even when they were exposed to DDK males. In the pharmacological induction of pregnancy block with dopamine agonist (Bromocriptine, 4mg/kg BW), BALB/cA females mated with BALB/cA males showed a 100% pregnancy block. In contrast, BALB/cA females mated with CBA/J, C3H/HeN, and C57BL/6Cr males showed higher pregnancy rates (40-70%). These results suggest that the better pregnancy rate of BALB/cA females mated with alien males may be due to the stronger viability of F 1 embryos. This interpretation was confirmed by an embryo transfer experiment in which a higher implantation rate was observed when BALB/cA embryos grown in BALB/cA females exposed to BALB/cA males were transferred into recipient BALB/cA females exposed to DDK males. These results suggest that the embryonic genotype or viability of the embryo is one factor contributing to the occurrence of pregnancy block by male pheromones in mice.

• 재활복지
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• v.22 no.3
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• pp.189-208
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• 2018

This case study investigated the changes in speech intelligibility of patients with head and neck cancers who participated in a therapeutic singing-based intervention. Three patients received a total of twelve 30-minute individual sessions. The intervention consisted of three steps: movements for relaxing breathing muscles, vocalization for increasing the range of articulatory movements, and therapeutic singing. In order to examine the changes in speech intelligibility, the voice quality parameters, diadochokinesis (DDK) and the quadrangle vowel space area (VSA) were measured at pre- and posttest. The recording of what each patient read a written paragraph, which were transcribed by blinded assessors, were also analyzed. The results demonstrated that all of the patients showed positive changes in the voice quality, the rate of repetitive syllable production measured by DDK, and the articulatory working space measured by VSA. Along with these measured changes, increases in positive mood and rehabilitation motivation reported by the patients support that the therapeutic singing-based intervention could induce meaningful changes in terms of speech intelligibility from patients with head and neck cancers. Given that this study was conducted with a small sample size, suggestions for further investigation on the effects of the intervention were also presented.

• Speech Sciences
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• v.15 no.4
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• pp.171-188
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• 2008

This study was purposed to introduce Korean Oro-motor Mechanism Screening Examination (KOMSE) and to provide the standardized scores taken from 120 normal adults aged $18{\sim}59$. KOMSE was composed of 13 items of structure, 17 items of function, 3 items of voice, and 14 items of regularity and accuracy of articulation during diadochokinesis. Additionally, maximum phonation time and diadochokinetic rates were measured. Total score of KOMSE is ranged from 0 to 200. It was significantly higher in the $50{\sim}59$ age group than in the $20{\sim}29$ age group, but was not significantly different in sex. MPT had a significant difference in sex, but no significant difference among different age groups. The rate of DDK was also had no significant difference among different age groups. However, some reducing trend in the rate of DDK was observed as age increased. KOMSE would be very helpful for SLPs to screen the abnormality of oro-motor mechanism.

• Proceedings of the IEEK Conference
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• 2000.11d
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• pp.259-262
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• 2000

One of the major factors determining the printing quality of a color printer is the color matching that is performed inside the printer driver In this paper, the mini driver for the color printer is built using the Microsoft 98DDK. Also, the ICC profile proposed as the standard for the color management system is generated. The color matching capability of the mini driver with the ICC profile is examined and compared with that of the commercial printer driver.

• Speech Sciences
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• v.15 no.4
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• pp.159-170
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• 2008

The purpose of this study was to find out the ability of coordination of the articulatory motor and the ability of control of the respiration and laryngeal for spastic dysarthria by acoustic analysis. The sustained of vowel /a/ and repetition of syllable /pa/ in 15 normal and 10 spastic dysarthria were measured. Multi-Speech, MDVP, and MSP were used for data recording and analysis. As a result, the mean DDK rate in the spastic group was significantly slower than in the normal. The maximum phonation time in the spastic group ($4.80{\pm}1.94$) was shorter than in the normal ($11.20{\pm}3.72$). The DDKjit in the spastic group was significantly higher than in the normal. The DDKsla was reduced in the spastic group. The mean syllable duration in the spastic group (146.2ms) was significantly longer than in the normal (75.8ms). The mean energy was reduced in the spastic group. The range of Fo was greater than in the normal. The frequency perturbation (jitter, vFo) and amplitude perturbation (shimmer, vAm) were higher than in the normal group. The NHR was higher than in the normal group. The parameters of this were significantly difference between the spastic dysarthria and the normal (p<0.05). Finally, the spastic dysarthria has short respiration, slow speech rate, and voice quality problem. The these results will help to establish a plan and the intervention of treatment.

• Korean Journal of Veterinary Research
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• v.40 no.4
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• pp.683-689
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• 2000

The present study was carried out to investigate the blood markers of Thoroughbred horses (TB) The blood red cell types and blood protein types (biochemical polymorphisms) were tested from 1,125 Thoroughbred horses by serological and electrophoretic procedures, and their phenotypes, gene frequencies, heterozygosity, polymorphic information content values and exclusion probability were estimated. The blood group and biochemical polymorphism phenotypes observed with high frequency were Aaf(91.7%), Ca(94.7%), K-(94.5%), Ua(75.9%), P-(50.6%), Qabc(82.6%), ALB-BB(67.7%), GC-FF(92.7%), AIB-KK(99.6%), ES-II(77.9%), TF-DF1(23.6%), PI-LL(23.2%), HB-B2B2(73.6%), PGD-FS(45.4%) and genotypes Dcgm/dk(16.9%), Dbcm/cgm(13.6%), Dbcm/dk(11.9%), Dcegmn/cegmn(10.0%), Dcgm/cgm(8.7%) in TB. Alleles observed with high frequency were Aaf(0.796), Ca(0.769), Ddk(0.266), Dcgm(0.261), Dbcm(0.211), K-(0.972), P-(0.710), Qabc(0.565), Q-(0.368), Ua(0.509), $HB^{B2}$(0.858), $PGD^F$(0.634), $ALB^B$(0.825), $GC^F$(0.927), $AIB^K$(0.998), $ES^I$(0.881), $TF^{F1}$(0.346), $TF^D$(0.319), $TF^{F2}$(0.184), $PI^L$(0.479), $PI^N$(0.214), $PI^U$(0.116) in TB. The heterozygosity, polymorphic information content (PIC) and exclusion probability (PE) were calculated. The mean heterozygosity and PIC value were 0.3899 and 0.3375, respectively. The highest heterozygosity and PIC were estimated 0.7834 and 0.7492 in blood group D locus, respectively. The cumulated PE obtained by blood groups and biochemical polymorphisms was 0.9813.