Park, Won-Il;Park, Si-Young;Choi, Hyun-Min;Lee, Joon-Hee;Jeon, Jong-Mok;Kim, Jong-Kyung;Shim, Jae-Kun;Nho, Ho-Sung
Journal of Life Science
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제19권11호
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pp.1568-1574
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2009
The purpose of this study was to investigate whether group III muscle afferents play an important role eliciting abnormal blood pressure response mediated during passive muscle stretch in prehypertensive individuals. Eleven middle-aged prehypertensive men (average BP 133/80 mmHg) and nine middle-aged normotensive men (average BP 119/74 mmHg) participated in this study. After 1 min rest baseline data collection, the subject's foot was flexed (dorsiflexion) by an automated cybex for one minute. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), heart rate, stroke volume, cardiac output, and total peripheral resistance were continuously measured on a beat-by-beat basis from a finger via a Finapres device for 1 minute. To evaluate the role of mechanoreflex, a component of exercise pressor reflex, SBP, DBP, and MAP responses over the course of time were examined. The results showed that the pressor response mediated by the muscle mechanoreflex was faster in prehypertensive individuals compared to the normotensive individuals. The substantial pressor response was observed within mean 20 sec of the onset of passive stretch in prehypertension, while mean 45 sec in normotension (p<0.05). It is concluded that excessive pressor response produced during exercise in prehypertension may be due to the dysfunction of the mechano-receptors.
Journal of Korean Society of Environmental Engineers
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제27권5호
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pp.461-467
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2005
Phthalate esters is recently considered as an environmental pollutant. This study investigated removal methods of phthalate esters in water environment. On tap water treatment condition with batch test, removal efficiency of coagulation precipitation of one oxidation were $26.6{\sim}33.8%$ and $10{\sim}15%$, respectively. Phthalate esters was effectively removed by the activated carbon adsorption process on tap water treatment condition. The operation of raw water with EBCT of 10 minutes on continuous process satisfied the standard of drinking water by the WHO and US EPA when the concentration of phthalate esters was $100\;{\mu}g/L$. On pilot plant test, coagulation precipitation process got $32{\sim}44%$ of removal efficiency, sand filtration process $6{\sim}10%$ and ozone oxidation process $8{\sim}10%$, respectively. DEP, DBP, BBP and DEHP were not detected after the raw water was processed with activated carbon. The actual survey of phthalate esters removal by advanced water treatment showed that $29{\sim}76%$, $3{\sim}29%$ and $17{\sim}22%$ of phthalate esters were removed on coagulation precipitation process, sand filtration and ozone oxidation process, respectively. DEP, DBP, BBP and DEHP were not detected after the raw water was processed with activated carbon.
This study was performed to determine the dietary risk factors associated with hypertension. The hypertensive group were composed of 112 hypertensive patients (male 53, female 59) who first visited the hypertension clinic and had been diagnosed as having primary hypertension ($SBP{\ge}140mmHg\;or\;DBP{\ge}90mmHg$). The regular visitors or the subjects on special diets or medical therapies were excluded. The normal group consisted of as subjects (male 41, female 54) matched with age and socioeconomic levels. The subjects having higher intakes (above the 75 percentile) in energy, protein, iron, vitamin A or C showed significantly higher hypertension risk estimated with odds ratio after the covariance factors (age, sex and BMI) were adjusted. More than 2400 mg of sodium (6 g of salt) intake was associated with significantly higher risk of hypertension (odds ratio: 1.773, CI: 1.014-3.014 for $SBP{\ge}140mmHg$; odds ratio: 2.373, CI: 1.359-4.215 for $DBP{\ge}90mmHg$). Hypertensive group showed significantly increased intakes of vegetables and fish and shell fish compared to the normal group. When the vegetable intakes were classified into Kimchi, fresh vegetables and cooked vegetables with seasoning, the hypertensive group was observed as having higher intakes of Kimchi and cooked vegetables with seasoning. The intakes of highest quartile for vegetables (${\ge}327g/day$) (odds ratio: 3.164, CI: 1.740-5.752), fish and their products (${\ge}102g/day$) (odds ratio: 2.756, CI: 1.486-5.109), grains(${\ge}311g/day$) (odds ratio 2.393, CI: 1.186-4.832), meats and their product (${\ge}106g$) (odds ratio: 2.210, CI: 1.225 - 3.987) compared to the lower were significantly associated with the higher risk of hypertension estimated with DBP (${\ge}90mmHg$) after covariance factors were adjusted. In conclusion, our findings confirm that higher intake of energy or sodium are associated with the increased risk of hypertension. Because increased intake of vegetable or fish was associated with the higher risk of hypertension, in contrast with the finding of western countries, choosing or preparation of vegetables or fish with reduced salt is recommended.
The principal objective of this study was to assess the effects of eating habits and health-related lifestyle on blood pressure, $\gamma$-Glutamic acid Peptide Transferase ($\gamma$-GPT), glucose and HDL-Cholesterol (HDL-C). All subjects (261 male, 252 female) were from the Iksan area of Korea, and were at least 50 years of age. The mean systolic blood pressure (SBP), diastolic blood pressure (DBP) and HDL-C for all the subjects was 131.3 mmHg, 78.5 mmHg, and 43.1 mg/dl, respectively. The HDL-C of the $50{\sim}64$ year-old group was higher than that of the over-75-year-old group. The "regular breakfast" group evidenced a lower SBP, $\gamma$-GPT, and higher HDL-C than the "seldom breakfast" group (p<0.001, p<0.001, p<0.01). SBP in the "snacking everyday" group was higher than that of the "seldom snacking" group (p<0.001). As for the frequency of using alcohol, SBP and $\gamma$-GPT for the group using alcohol everyday were higher than those of the non-drinking group (p<0.001, p<0.001), SBP and DBP were higher and $\gamma$-GPT was lower in the group that regularly drank more than 4 glasses of Soju than in the non-drinking group (p<0.001, p<0.05, p<0.001). SBP, DBP, and $\gamma$-GPT for the "heavy smoker" group were higher than those of the non-smoker group (p<0.01, p<0.01, p<0.05). The HDL-C was lower in the "heavy smoker" group than in the "non-smoker" group (p<0.05). The SBP with exercise was as follows: Group 1 ($0.022{\sim}0.073\;kcal/min/kg$) was lower than that of Group 3 ($0.144{\sim}0.161\;kcal/min/kg$) and Group 4 (0.161 kcal/min/kg) (p<0.001). To conclude: advancing age, snacking, and frequent alcohol consumption increased blood pressure; the lowest blood pressure was detected in the group that ate breakfast everyday and in the group that engaged in more frequent exercise; Moreover, $\gamma$-GPT was higher and HDL-C was lower in the smokers' group than in the non-smokers' group. Considering the results of this study, there appears to be an urgent need to instruct aging adults about eating breakfast everyday, reducing smoking, using less or no alcohol, and getting proper and regular exercise.
Kim, Young-Min;Kim, So-Yeon;Cheong, Hae-Kwan;Ahn, Byun-Gok;Choi, Kyu-Sik
Environmental Analysis Health and Toxicology
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제27권
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pp.13.1-13.10
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2012
Objectives: We aimed to investigate the acute effects of heat stress on body temperature and blood pressure of elderly individuals living in poor housing conditions. Methods: Repeated measurements of the indoor temperature, relative humidity, body temperature, and blood pressure were conducted for 20 elderly individuals living in low-cost dosshouses in Seoul during hot summer days in 2010. Changes in the body temperature, systolic blood pressure (SBP) and diastolic blood pressure (DBP) according to variations in the indoor and outdoor temperature and humidity were analyzed using a repeated-measures ANOVA controlling for age, sex, alcohol, and smoking. Results: Average indoor and outdoor temperatures were $31.47^{\circ}C$ (standard deviation [SD], $0.97^{\circ}C$) and $28.15^{\circ}C$ (SD, $2.03^{\circ}C$), respectively. Body temperature increased by $0.21^{\circ}C$ (95% confidence interval [CI], 0.16 to $0.26^{\circ}C$) and $0.07^{\circ}C$ (95% CI, 0.04 to $0.10^{\circ}C$) with an increase in the indoor and outdoor temperature of $1^{\circ}C$. DBP decreased by 2.05 mmHg (95% CI, 0.05 to 4.05 mmHg), showing a statistical significance, as the indoor temperature increased by $1^{\circ}C$, while it increased by 0.20 mmHg (95% CI, -0.83 to 1.22 mmHg) as outdoor temperature increased by $1^{\circ}C$. SBP decreased by 1.75 mmHg (95% CI, -1.11 to 4.61 mmHg) and 0.35 mmHg (95% CI, -1.04 to 1.73 mmHg), as the indoor and outdoor temperature increased by $1^{\circ}C$, respectively. The effects of relative humidity on SBP and DBP were not statistically significant for both indoor and outdoor. Conclusions: The poor and elderly are directly exposed to heat waves, while their vital signs respond sensitively to increase in temperature. Careful adaptation strategies to climate change considering socioeconomic status are therefore necessary.
Journal of the Korea Academia-Industrial cooperation Society
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제16권5호
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pp.3323-3332
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2015
The purpose of this study was to investigated the effects of alcohol intake on blood pressure, serum lipids, liver function tests and obesity indices in middle-aged male workers. The 2,175 male workers aged 30-59 years who examined health checkup were recruited as the study subjects during the period between January to December, 2013. We observed the relationships between the amount of alcohol intake and blood pressure, serum lipids, liver function tests and obesity indices. As a result, the mean score of SBP, DBP, LDL-C and TG were significantly higher increasing with amount of alcohol increased, but HDL-C were significantly lower increasing with amount of alcohol increased. AST, ALT, ALP and ${\gamma}$-GTP were significantly higher increasing with amount of alcohol increased, but obesity indices were not significant. Age adjusted odds ratios(ORs) increasing with abnormal levels of SBP, DBP, HDL-C, LDL-C, TG, AST and ALT were significantly increased in heavy drinking group than light drinking group. Above results suggested that the heavy drink related with blood, serum lipid levels and liver function test levels, but not find out with obesity indices.
Journal of the Korea Academia-Industrial cooperation Society
/
제14권3호
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pp.1359-1366
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2013
The purpose of this study was to examine the blood pressure, serum lipid levels and obesity indices according to smoking status, and the effects of smoking cessation on blood pressure, serum lipid and obesity indices. The 2,230 male workers aged 30-59 years were observed the age, smoking status, SBP, DBP, TC, TG, HDL-C, LDL-C, AI, BMI, body fat rate and waist circumference, from April to July, 2011. As a results, the mean score of SBP, DBP, TC, TG and BMI were significantly higher in smoking group than non-smoking group, but HDL-C were significantly lower in smoking group than non-smoking group, the distribution of hypertension was significantly higher in smoking group than non-smoking group. The abnormal levels of TC, TG and HDL-C were significantly higher in smoking group than non-smoking group, and the distribution of obesity was significantly higher in smoking group than non-smoking group. Age adjusted odds ratio(ORs) was significantly increase in smoking group than non-smoking group: hypertension(3.59 times), hypercholesteremia (1.49 times), hyperlipidemia(1.81 times), low HDL-cholesteremia(1.58 times), high level of atherogenic index(1.27 times). Above results suggested that the smoking related with blood pressure and serum lipid levels.
This study examined how achievement of session goals contributes to outcomes of subjects after participation in a 12-week lifestyle intervention program in men with metabolic syndrome (MetS). Thirty office workers with MetS, aged $47.2{\pm}6.6$ years, participated in this study, from March to July, 2011. The intervention program included face-to-face counseling five times during the 12-week period. Counselors and subjects designed session goals for each round. The average of the goal achievement rate was calculated based on compliance for each round. The subjects were divided into three groups according to their tertiles of achievement rate: Low-compliance group (LC, < 59%), medium-compliance group (MC, 59-70%), and high-compliance group (HC, > 70%). Anthropometry, biochemical index, and nutrient intake were examined at baseline and at the end of the 12-week intervention program. After the intervention, diastolic blood pressure (DBP) showed a significant decrease in the LC group, and waist circumference (WC) showed a significant decrease in the MC group. Systolic blood pressure (SBP), DBP, and low-density lipoprotein cholesterol (LDL) showed a significant decrease in the HI group. Changes in SBP and DBP were significantly lower in the HC group than in the MC group (p < 0.05, p < 0.01). Changes in LDL were significantly lower in the HC group than in the MC group (p < 0.05). Results for intake of total energy, protein, fat, and sodium, as well as rates of carbohydrate and fat intake, showed a significant decrease in all participants (p < 0.05). The change in fiber was significantly higher in the HC group than in the MC group (p < 0.05). The change of fruit serving size showed a significant increase in the HC group (p < 0.01). The number of risk factors for MetS showed a significant decrease in the LC and HC groups (p < 0.05), however, no significant mean differences were observed among the three groups. In conclusion, participation in this intervention program resulted in positive effects on risk factors for MetS, nutrient intake, and dietary habits, especially in the High-compliance group.
The purpose of this study was to compare the preventive effects of green tea and coffee drinking on postprandial hypotension in the elderly. A total of 30 women ($81.2{\pm}6.8years$) who had experience of postprandial hypotension participated 3 interventions by random order allocation. During the experimental interventions, each participant had a cup of instant coffee (60mg caffeine), or green tea (15.8mg caffeine) after lunch, and control group had only their lunch. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured with 15 minute interval from 30 minutes before the meal to 120 minutes after the meal. The preprandial SBP and DBP were not significantly different between three groups. Postprandial SBP reduction measured at the 1 hour after meal was significantly smaller in coffee group compared to the control group, whereas green tea group was not ($-15.1{\pm}17.9mmHg$ vs $-13.4{\pm}22.4mmHg$ vs. $-4.1{\pm}18.6mmHg$ for control, green tea, and coffee group, respectively, p=.032). Likewise, DBP decrement at the 1 hour after meal was significantly smaller in coffee than control group ($-12.8{\pm}13.0mmHg$ vs $-6.9{\pm}16.6mmHg$ vs $-0.8{\pm}13.4mmHg$ respectively, p=.033). The HR response of the three groups were not significantly different throughout the intervention. Coffee drinking was potentially beneficial for preventing postprandial hypotension and resultant falling event.
Proceedings of the Korean Society of Soil and Groundwater Environment Conference
/
한국지하수토양환경학회 2004년도 총회 및 춘계학술발표회
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pp.358-361
/
2004
The photocatalytic degradation of Endocrine Discruptors, dibuthyl phthalate(DBP) has been investigated over TiO$_2$ photocatalysts irradiated with a ultraviolet (UV) light. The effect of operational parameters, i.e., reaction time, light intensity, pH and additive on the degradation rate of aqueous solution of Endocrine Discruptors has been examined. Results show that the employment of efficient photocatalysts and the selection of optimal operational parameters may lead to degradation of Endocrine Discruptors solutions.
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