• Title/Summary/Keyword: DAR(1)

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Risk Factors for Preterm Birth and Low Birth Weight in Extramarital Birth: 2008-2012 Birth Certificated Data (혼외 출생아의 조기분만과 저체중아 발생 위험도에 관한 연구: 2008-2012년 출생통계)

  • Lim, Dar-Oh;Park, Sang-Hwa
    • The Korean Journal of Health Service Management
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    • v.8 no.3
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    • pp.137-145
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    • 2014
  • The objective of this study was to analyze the risk of preterm birth (PTB) and low birth weight (LBW) in extramarital birth by analyzing 2008-2012 birth certificated data (2,328,719 births) from Korea Statistics. Odds ratio and 95% confidence intervals (95% CI) were calculated from logistic regression analyses to describe the associations between PTB & LBW and extramarital birth adjusted for maternal age, maternal occupation & education, infantile sex, birth order and number of child birth (singleton & multiple birth). The rate of extramarital birth was 1.8 percent and 2.1 percent in 2010-11. The incidence of LBW was 8.1 percent in extramarital birth and 5.0 percent in marital birth. The incidence of PTB in extramarital birth were 8.2 percent and 5.8 percent in marital birth. Compared with marital birth, the odds ratio (OR) for PTB were 1.48 (95% CI: 1.43-1.54) for extramarital birth. Risk of LBW was higher in extramarital birth (OR: 1.70, 95% CI: 1.64-1.76) than that of marital birth. Among mothers younger than 20 years, the odds ratio of PTB among extramarital birth, relative to married birth was 1.69 (1.49-1.91). Among unmarried mothers, those at a higher risk of LBW was aged 20-29 years (1.69: 1.59-1.79). Maternal unmarried status was associated with increased risk of PTB and LBW.

Leu432Val Polymorphism of CYP1B1 is Not Associated with Squamous Cell Carcinoma of Esophagus - a Case-Control Study from Kashmir, India

  • Shah, Idrees Ayoub;Mehta, Promila;Lone, Mohd Maqbool;Dar, Nazir Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5337-5341
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    • 2015
  • Background: Individual susceptibility to cancer has been attributed to polymorphisms in xenobiotic metabolizing genes. To evaluate the association of the Leu432Val polymorphism of cytochrome P4501B1 (CYP1B1) with esophageal squamous cell carcinoma (ESCC), we conducted a case control study in Kashmir, India, an area with a relatively high incidence of ESCC. Materials and Methods: We recruited 404 histopathologically confirmed ESCC cases, and an equal number of controls, individually matched for sex, age and district of residence to respective cases. Information was obtained on various dietary, lifestyle and environmental factors in face to face interviews, using a structured questionnaire, from each subject. Genotypes were analysed by polymerase chain reaction, restriction fragment length polymorphism and sequencing of randomly selected samples. Conditional logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs). Results: Among the three possible variants, we did not find any Leu432Leu genotype of CYP1B1 in the study population and the genotypic distribution of Val432Val and Leu432Val carriers was nearly equal in both cases (89.6% and 10.4%) and controls (88.9% and 11.1%) respectively. We did not find any risk associated with this polymorphism in the current study (OR = 0.64; 95% CI: 0.55 - 1.64). Conclusions: The study indicates that (Leu432Val) polymorphism of CYP1B1, is not associated with ESCC risk. However, replicative studies with larger sample size are needed to substantiate the findings.

True Orthoimage Generation from LiDAR Intensity Using Deep Learning (딥러닝에 의한 라이다 반사강도로부터 엄밀정사영상 생성)

  • Shin, Young Ha;Hyung, Sung Woong;Lee, Dong-Cheon
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.38 no.4
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    • pp.363-373
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    • 2020
  • During last decades numerous studies generating orthoimage have been carried out. Traditional methods require exterior orientation parameters of aerial images and precise 3D object modeling data and DTM (Digital Terrain Model) to detect and recover occlusion areas. Furthermore, it is challenging task to automate the complicated process. In this paper, we proposed a new concept of true orthoimage generation using DL (Deep Learning). DL is rapidly used in wide range of fields. In particular, GAN (Generative Adversarial Network) is one of the DL models for various tasks in imaging processing and computer vision. The generator tries to produce results similar to the real images, while discriminator judges fake and real images until the results are satisfied. Such mutually adversarial mechanism improves quality of the results. Experiments were performed using GAN-based Pix2Pix model by utilizing IR (Infrared) orthoimages, intensity from LiDAR data provided by the German Society for Photogrammetry, Remote Sensing and Geoinformation (DGPF) through the ISPRS (International Society for Photogrammetry and Remote Sensing). Two approaches were implemented: (1) One-step training with intensity data and high resolution orthoimages, (2) Recursive training with intensity data and color-coded low resolution intensity images for progressive enhancement of the results. Two methods provided similar quality based on FID (Fréchet Inception Distance) measures. However, if quality of the input data is close to the target image, better results could be obtained by increasing epoch. This paper is an early experimental study for feasibility of DL-based true orthoimage generation and further improvement would be necessary.

Rechtliche Probleme uber $Verf\ddot{u}gung\;\ddot{u}ber$ Teile des menschlichen $K\ddot{o}rpers$ - unter besonderer Berucksichtigung der Lage von Deutschland - (인체사료의 처분에 관한 법률문제 - 독일의 논어를 중심으로 -)

  • Choi, Jun-Hyouk
    • The Korean Society of Law and Medicine
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    • v.8 no.1
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    • pp.35-57
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    • 2007
  • Hier zu behandelndes Thema ist ein altes Problem beim Recht, das seinen Ursprung sogar im romischen Recht finden kann. Aber wegen der medizinischen und naturwissenschaftlichen Entwicklung $t\ddot{a}ucht$ es wieder mit anderen Konstellationen auf. Dabei geht es besonders darum, ob sich die Patienten an der kommerziellen Nutzung seiner $K\ddot{o}rpersubstanzen$ von anderen-z. B. $\ddot{A}rzten$ oder Forschern-beteiligen $k\ddot{o}nnen$. $Daf\ddot{u}r$ gibt es in Bezug auf Gesetz keine besonderen Regelungen in Deutschland. Und nach zivilrechtlicher Theorie stellt Nutzung menschlicher $K\ddot{o}rpersubstanzen$ eine Personlichkeitsverletzung des fruheren $Tr\ddot{a}gers$ und/oder eine Verletzung des Arzt-Patienten-Vertrages dar. $Au{\beta}erdem$ ist Anspruch des $fr\ddot{u}heren\;Tr\ddot{a}gers$ debkbar, der auf dessen Einwilligung basiert. Dabei sind diese Probleme $zun\ddot{a}chst$ unter $Pers\ddot{o}nlichkeitsverletzung$ zu subsumieren und damit zu $l\ddot{o}sen$.

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Permanent Ground Deformation induced by Christchurch Earthquake and Estimation of Underground Water Pipeline Performance in New Zealand (뉴질랜드 크라이스트처어치 지진에 의해 발생된 영구지반변형과 매설된 상수도관 성능평가)

  • Jeon, Sang-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.4201-4207
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    • 2015
  • In this study, the performance of underground water pipeline system affected by earthquakes is examined by using data acquired after MW 6.2 February 22, 2011 earthquake in Christchurch, NZ. Water pipeline repair rates, expressed as repairs/km, for different types of pipe are evaluated inside the areas of which liquefaction induced by permanent ground deformation was observed and assessed relative to differential settlement and lateral ground strain, calculated from high resolution LiDAR data acquired before and after each seismic event. The earthquake performance of underground water pipeline systems associated with permanent ground deformation is summarized in this paper. The results show that highly ductile polyethylene water pipelines has a high earthquake performance.

Reactions to Store Environment and Interpersonal Service Quality in Supermarkets vs Hypermarkets

  • MZOUGHI, Mohamed Nabil;GARROUCH, Karim Fraj
    • Journal of Distribution Science
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    • v.20 no.1
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    • pp.67-76
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    • 2022
  • Purpose: The purpose is to verify the impact of the store environment on interpersonal service quality (ISQ), shopping value and patronage intention, as well as the moderating role of the store format: supermarkets vs hypermarkets. This is significant as previous studies on retailing neglected the effect of interpersonal service quality on the experiential shopping value. The comparison of the model between two retailing formats (hypermarkets and supermarkets) provides a significant contribution and responds to a need to provide insights regarding the moderation of the store types on the contribution of interpersonal service quality and experiential value to customer's retention. Research design, data, and methodology: The hypotheses have been tested after analyzing the data of a survey among 405 consumers exiting stores representing various retailing stores in Tunisia. A Structural model have been finally verified by a path analysis after applying a confirmatory factorial analysis. Multigroup analyses on AMOS allowed to verify the moderation of store types. Results: Results mainly show that patronage intention is affected by the experiential perceived value dimensions. The latter is a direct consequence of ISQ and an indirect outcome of perceived shopping environment. The impact of value, environment and ISQ is moderated by the store type.

Mucin modifies microbial composition and improves metabolic functional potential of a synthetic gut microbial ecosystem

  • Mabwi, Humphrey A.;Komba, Erick V.G.;Mwaikono, Kilaza Samson;Hitayezu, Emmanuel;Mauliasari, Intan Rizki;Jin, Jong Beom;Pan, Cheol-Ho;Cha, Kwang Hyun
    • Journal of Applied Biological Chemistry
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    • v.65 no.1
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    • pp.63-74
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    • 2022
  • Microbial dysbiosis in the gut is associated with human diseases, and variations in mucus alter gut microbiota. Therefore, we explored the effects of mucin on the gut microbiota using a community of 19 synthetic gut microbial species. Cultivation of these species in modified Gifu anaerobic medium (GAM) supplemented with mucin before synthetic community assembly facilitated substantial growth of the Bacteroides, Akkermansia, and Clostridium genera. The results of 16S rRNA microbial relative abundance profiling revealed more of the beneficial microbes Collinsella, Bifidobacterium, Ruminococcus, and Lactobacillus. This increased acetate levels in the community cultivated with, rather than without (control), mucin. We identified differences in predicted cell function and metabolism between microbes cultivated in GAM with and without mucin. Mucin not only changed the composition of the gut microbial community, but also modulated metabolic functions, indicating that it could help to modulate microbial changes associated with human diseases.

Evaluation of Applicability of 2D River Flow Analysis Model using River Surveying Data (드론 측량 데이터를 이용한 2차원 하천 흐름 해석 모형의 적용성 평가)

  • Shin, Eun Taek;Eum, Tae Soo;An, Seheck;Song, Chang Geun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.242-242
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    • 2022
  • 실제 자연하천은 하천의 만곡, 사행 정도와 교각 및 암거와 같은 구조물로 인하여 발생하는 복잡한 흐름현상이 빈번하게 발생하며, 이를 반영하기 위해서는 2차원 흐름해석 모형의 적용이 필요하다. 이러한 필요성이 있음에도 현재 하천흐름해석 분야 실무에서 사용되는 모형은 1차원 모형이 주를 이루고 있으며, 그 이유는 현재 제공되고 있는 하천 단면 자료와의 높은 적용성 때문이라고 할 수 있다. 현행 제공되고 있는 하천 단면 자료는 인력 위주의 측량 자료로서 하천 연장의 일정구간 간격으로 단면 자료를 제공하고 있기 때문에 2차원 흐름해석 모형에 적용하기 위해서는 보간 작업이 필수적이며, 정확성 또한 낮아 적용성이 떨어지는 문제점이 있다. 하지만 최근 드론을 이용한 측량 기술의 발전으로 LiDAR, 초분광을 활용한 양질의 2차원 하천 하상 자료를 산출하기 시작하였으며, 하천흐름해석 분야에서 2차원 흐름해석 모형의 적용성이 높아지고 있다. 본 연구에서는 기존에 적용하기 어려웠던 사행도가 높은 하천에 대하여 드론 측량 자료를 활용한 2차원 흐름해석 모형 결과와 기존의 측량 방식을 적용한 2차원 흐름해석 모형 결과 비교를 통하여 드론 측량 자료를 활용한 2차원 흐름해석 모형의 적용성 평가를 수행하고자 한다.

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Survival after extended resections for gallbladder cancer

  • Abu Bakar Hafeez Bhatti;Faisal Saud Dar;Shahzad Riyaz;Nusrat Yar Khan;Najla Rahman Qureshi;Nasir Ayub Khan
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.1
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    • pp.70-75
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    • 2023
  • Backgrounds/Aims: Locally advanced gallbladder cancer (GBC) is associated with survival limited to a few months. Extended resections (ER) are occasionally performed in this group and outcomes remain inconclusive. This study assessed outcomes after ER for locally advanced GBC. Methods: Patients who underwent ER for GBC between 2011 and 2020 were reviewed. ER was defined as a major hepatectomy alone (n = 9), a pancreaticoduodenectomy (PD) with or without minor hepatectomy (n = 3), a major hepatectomy with PD (HPD) (n = 3) or vascular resection and reconstruction (n = 4). We assessed 30-day morbidity, mortality, and 2-year overall survival (OS). Results: Among 19 patients, negative margins were achieved in 14 (73.6%). The 30-day mortality was 1/9 (11.1%) for a major hepatectomy, 0/3 (0%) for a minor HPD, 2/3 (66.7%) for a major HPD, and 1/4 (25.0%) for vascular resection. All short term survivors (< 6 months) (n=8) had preoperative jaundice and 6/8 (75.0%) underwent a major HPD or vascular resection. There were five (26.3%) long term survivors. The median OS in patients with and without preoperative jaundice was 4.1 months (0.7-11.1 months) and 13.7 months (12-30.4 months), respectively (p = 0.009) (2-year OS = 7% vs. 75%; p = 0.008). The median OS in patients who underwent a major hepatectomy alone or a minor HPD was 11.3 months (6.8-17.3 months) versus 1.4 months (0.3-4.1 months) (p = 0.02) in patients who underwent major HPD or vascular resection (2 year OS = 33% vs. not reached) (p = 0.010) respectively. Conclusions: In selected patients with GBC, when ER is limited to a major hepatectomy alone, or a minor HPD, acceptable survival can be achieved.

Regional Suicide Mortality Rate in Korea (지역별 고의적 자해에 의한 사망수준에 관한 연구)

  • Park, Sang-Hwa;Kim, Young-Bae;Lim, Dar-Oh
    • The Korean Journal of Health Service Management
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    • v.7 no.3
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    • pp.287-296
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    • 2013
  • The aim of this study was to compare the regional difference of death from intentional self-harm. The analysis was based on data of intentional self-harm deaths (31,450) from the 2010-2011 vital statistics of Korea. The suicide rate (per 100,000 population) was 46.2 in male and 22.3 in female. Gender ratio (male / female) of suicide rate was 2.07, and Jeju province had the lowest gender ratio (1.82), and Chungbuk province had the highest gender ratio (2.42). In the age-gender standardized death rate (per 100,000) of self-harm by region, the highest suicide rate was observed in Gangwon province (44.8) and Chungnam province (44.3), and the lowest in Seoul metropolitan city (28.9) and Ulsan metropolitan city (29.2). There was a significant increase in the rate of suicide in city areas (odds ratio: 1.11, 95% CI: 1.08-1.13), county areas (1.62, 1.56-1.67) as compared with the rate of suicide in metropolitan areas. The commonest methods of suicide were hanging (53.7 percent), self-poisoning by pesticides (16.8 percent) and jumping from a height (14.3 percent). The methods used for suicide differed between rural (county) and urban areas (metropolitan city and city). In county areas, 43 percent of suicides used pesticides as compared to only 7-18 percent of those in urban areas. In urban areas, jumping was more common (13-17 percent vs. 6 percent). There were no difference in hanging between urban and rural areas. The odds ratio of death by pesticides was 9.86 in rural areas compared with death rate of metropolitan areas. The odds ratio of death by jumping was 0.59 in rural compared with death rate of metropolitan areas.