• Korean Journal of Biological Psychiatry
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• v.24 no.1
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• pp.26-31
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• 2017

Objectives A normal circadian rhythm of autonomic nervous system function stands for the daily change of sympathetic and parasympathetic modulation, which can be measured by heart rate variability (HRV). Generally, patients in the intensive care unit (ICU) are prone to sleep-wake cycle dysregulation, therefore, it may have an influence on the circadian rhythm of autonomic nervous system. This study was designed to interpret possible dysregulation of autonomic nervous system in ICU patients by using HRV. Methods HRV was assessed every 3 hours in 21 ICU patients during a 7-minute period. The statistical differences of HRV features between the morning (AM 6 : 00-PM 12 : 00), and the afternoon (PM 12 : 00-PM 18 : 00) periods were evaluated in time domain and frequency domain. Results Patients showed significantly increased normalized power of low frequencey (nLF), absolute power of low frequencey (LF)/absolute power of high frequencey (HF) in the afternoon period as compared to the morning period. However, normalized power of high frequency (nHF) was significantly decreased in the afternoon period. There was no statistically significant difference between the morning period and the afternoon period in the time domain analysis. Conclusions The increased sympathetic tone in the afternoon period supports possible dysregulation in the circadian rhythm of autonomic nervous system in ICU patients. Future studies can help to interpret the association between autonomic dysregulation and negative outcomes of ICU patients.

• Development and Reproduction
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• v.18 no.3
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• pp.145-152
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• 2014

This study was performed to investigate the effect of of transdermal testosterone gel (TTG) on controlled ovarian stimulation (COS) and IVF outcomes and ovarian morphology according to pretreatment duration in poor responders. A total of 120 women were recruited for this pilot study. They were randomized into control, 2 weeks, 3 weeks or 4 weeks TTG treatment groups. For three TTG treatment groups, 12.5 mg TTG was applied daily for 2 weeks, 3 weeks or 4 weeks in preceding period of study stimulation cycle. After 3 weeks of TTG pretreatment, significant increase of antral follicle count (AFC) and significant decreases of mean follicular diameter (MFD) and resistance index (RI) value of ovarian stromal artery were observed (p=0.026, p<0.001, p<0.01, respectively). The total dose of rhFSH administered for COS significantly decreased after 3 and 4 weeks TTG treatment both compared with control group (p<0.001, p<0.001). The numbers of oocytes retrieved and mature oocytes were significanty higher in 3 and 4 weeks TTG treatment groups than control group (p<0.001, p<0.001 in the number of oocytes retrieved; p<0.001, p<0.001 in the number of mature oocytes). The clinical pregnancy rate and live birth rate were increased only in 4 weeks TTG treatment group compared with control group (p=0.030 and p=0.042, respectively). These data demonstrated that TTG pretreatment for 3 to 4 weeks increases AFC and ovarian stromal blood flow, thereby potentially improving the ovarian response to COS and IVF outcome in poor responders undergoing IVF/ICSI.

• Journal of Veterinary Clinics
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• v.7 no.2
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• pp.511-515
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• 1990

Induction of twinning was attempted by transfer of two whole- or demi-embryos in Holstein cows and heifers. Cows were superovulated with follicle stimulating hormone(FSH) administered twice daily in intra-muscular injection. On day of 6.5 to 7 post-estrus, embryos were collected nonsurgically, Normal morulae and early balstocysts were obtained from superovulated cows. The embryos were hisected with a micro-blade made from a razor. Twenty seven pairs of half embryos were successfully produced and 23 pairs of half embryos were transferred to recipients( Group A). Twenty cows were treated with low unit of FSH (3mg${\times}$2,2mg${\times}$2 ; Group B1, 2mg${\times}$2, 1mg${\times}$2, 1mg${\times}$2 ; Group 32) to induce double or triple ovulations. The cows of Group B1 and B2 were Inseminated artificially(A1) at following estrus. Twenty four heifers were bred by A1 and received an additional embryo into the uterine horn contralateral to the corpus luteum(CL) 6 days later(Group C). One embryo was transferred into each uterine hem of 16 heifers 6 days after estrus(Group D). Fourteen heifers were received two embryos into the uterine horn ipsilateral to the CL at day 6 of estrous cycle(Group I). Pregnancy rates at 60 days in Group A, B1, B2, C, D and E were 34.8％, 70.0％, 60.0％, 66.7％, 62.5％ and 57.1％, respectively. Twinning rates were 8.7％, 20.0%, 10.0％, 16.7％, 18.7％ and 21.4％, respectively. The present experiments demonstrate that FSH treatment( Group 31) and ipsilateral transfer( Group I ) of two whole-embryos are more useful methods to produce twins than the others.

• Journal of the Korean earth science society
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• v.22 no.1
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• pp.40-46
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• 2001

Heat exchange between the atmosphere and sea is produced using the data from two 3m discus buoy installed by KMA in 1996. The meteorological and oceanic characteristics at the Dukjukdo and Chilbaldo buoy for the period 1996 ${\sim}$ 2000 are discussed. Daily averaged sensible heat and latent heat flux at each site are estimated from bulk aerodynamic method using given data and analyzed. Quantitative analyses show SST indicates 1-year cycle like air temperature but has 1 month lag. Sea level pressure is lowest in July, humidity is higher from May to August, and wind speed has averaged value of 5 m/s and higher in autumn and winter. Sensible heat flux analyses present that strong heat loss from the sea occurs in autumn and winter and weak heat loss from atmosphere appears in spring and summer, and net sensible heat loss from the sea is found throughout the year. The ocean significantly releases latent heat into atmosphere from August to May but get a little latent heat from atmosphere in other months. Net latent heat loss from the sea is larger than net sensible heat loss except in January and February. Comparison with two sites suggests that the magnitude of heat flux and their fluctuation are generally stronger at Dukjukdo than at Chilbaldo. In case study, both sensible and latent heat flux is a little more at Chilbaldo in March 1998, but substantially stronger at Dukjukdo in November 1996.

• Journal of the Korean Home Economics Association
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• v.25 no.4
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• pp.141-152
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• 1987

The book of Sa So Jeol is about the moral training family precepts written by Yi Deok-mu (이덕무, 1739~1793) in the year of king Young Jo 51th in the Yi dynasty. The writer provides us, according to the views of Confucianists, with the principles that both elders and children of that time should abide by in the daily life, dividing the said books into 924 sections, 8 chapters, and 2 volumes. The parts concerned with children are studied in this essay. The brief conclusions are as follows. 1. Children were required to have the mental attitudes of honesty, patience, tolerance and frugality and were instructed to show such attitudes through their behavior. 2. Children were instructed to have the behavioral attitudes of nine aspects, which are the behavioral characteristics of the sages. They were instructed to emulate the personal characters of the sages through being possessed of these nine aspects, which are to be found in healthy and comfortable mental states. 3. Children were instructed to be careful and composed, in their activities. Since prudence is the basic principle of mental and behavioral attitudes, being required of men and women of all ages in a traditional society, it was emphasized from early childhood 4. The aim of instruction was taken to be becoming human, or becoming a virtuous man, rather than merely passing the classical government examamination, and for this aim the moral rules, which can be considered the order of human relations, were taught intensively. 5. As for instructional methods, the children were required to do careful or rough reading according to their abilities, and were instructed to listen to lectures politely, prudently, ardently and honestly. 6. The instructional contents are for the purpose of making children read the classical canons after increasing their perceptive ability in the various things of the sexagenary cycle, the multipicative method, the kings, lineage, and the reign-titles, and the accumulated knowledge of $\ulcorner$Kyung Mong Yo Kyul$\lrcorner$, $\ulcorner$Seong Hak Jeop Yo$\lrcorner$ and $\ulcorner$Keun Sa Lok$\lrcorner$. Because of the greater emphasis on natural talents rather than on acquired abilities, the children, however, were eudcated only after their despositions were examined. 7. The children were required to have warm-hearted, careful, polite, and prudent attitudes toward their elders, and were instructed to take precauticns against arrogance and impoliteness. Since politeness in particular was considered not only as the ground of decorum but the method of emotional regulation and maintaining composure for confucianists, it can be regarded as the principal ettiquettee demanded in all activities. 8. The main instructional contents are generally moral aspects, concentrating on introspection and virtuous conduct through emotional regulations, rather than on the natural expression of physical and mental states.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.1
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• pp.166-176
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• 2020

Objective: An experiment was conducted to determine the effects of L-arginine (L-Arg) and N-carbamoylglutamic acid (NCG) on the growth, metabolism, immunity and community of cecal bacterial flora of weanling and young rabbits. Methods: Eighteen normal-grade male weanling Japanese White rabbits (JWR) were selected and randomly divided into 6 groups with or without L-Arg and NCG supplementation. The whole feeding process was divided into weanling stage (day 37 to 65) and young stage (day 66 to 85). The effects of L-Arg and NCG on the growth, metabolism, immunity and development of the ileum and jejunum were compared via nutrient metabolism experiments and histological assessment. The different communities of cecal bacterial flora affected by L-Arg and NCG were assessed using high-throughput sequencing technology and bioinformatics analysis. Results: The addition of L-Arg and NCG enhanced the growth of weanling and young rabbit by increasing the nitrogen metabolism, protein efficiency ratio, and biological value, as well as feed intake and daily weight gain. Both L-Arg and NCG increased the concentration of immunoglobulin A (IgA), IgM, and IgG. NCG was superior to L-Arg in promoting intestinal villus development by increasing villus height, villus height/crypt depth index, and reducing the crypt depth. The effects of L-Arg and NCG on the cecal bacterial flora were mainly concentrated in different genera, including Parabacteroides, Roseburia, dgA-11_gut_group, Alistipes, Bacteroides, and Ruminococcaceae_UCG-005. These bacteria function mainly in amino acid transport and metabolism, energy production and conversion, lipid transport and metabolism, recombination and repair, cell cycle control, cell division, and cell motility. Conclusion: L-Arg and NCG can promote the growth and immunity of weanling and young JWR, as well as effecting the jejunum and ileum villi. L-Arg and NCG have different effects in the promotion of nutrient utilization, relieving inflammation and enhancing adaptability through regulating microbial community.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.744-754
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• 2017

In this study, an analytic hierarchy process (AHP) was conducted with the aim of developing a post-disaster refugee housing performance index system (PPS) to improve the post-disaster refugee housing (PRH) performance criteria for the foundation of quality-based development. The PRH was defined as a mid-term temporary housing facility that is used for a certain period before the permanent housing is established. The safety, rapidity, reusability, habitability, and economy were derived from major performance factors through prior research. A hierarchical PPS was organized by linking the major performance factors with the whole life cycle process of PRH. The priority of each performance index of PPS was determined quantitatively using the analytic hierarchy process through an expert survey. Based on AHP analysis, the performance criterion of the total weight 1-10 ranking and the performance criterion of the first rank in each category were classified into the essential performance criterion (must be achieved) and the others were classified into the recommended performance criterion (optional achieved) and the performance index was constructed considering all stages of PRH development. With the completion of the PRH performance index, it is expected that victims will be able to secure stable residence and return to their daily lives quickly.

• Journal of Korea Water Resources Association
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• v.40 no.6 s.179
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• pp.459-468
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• 2007

To estimate the groundwater recharge, the fully distributed parameter based model, MIKE SHE was applied to the Gyeongan-cheon watershed which is one of the tributaries of Han River Basin, and covers approximately $260km^2$ with about 49 km main stream length. To set up the model, spatial data such as topography, land use, soil, and meteorological data were compiled, and grid size of 200m was applied considering computer ability and reliability of the results. The model was calibrated and validated using a split sample procedure against 4-year daily stream flows at the outlet of the watershed. Statistical criteria for the calibration and validation results indicated a good agreement between the simulated and observed stream flows. The annual recharges calculated from the model were compared with the values from the conventional groundwater recession curve method, and the simulated groundwater levels were compared with the observed values. As a result, it was concluded that the model could reasonably simulate the groundwater level and recharge, and could be a useful tool for estimating spatially/temporally the groundwater recharges, and enhancing the analysis of the watershed water cycle.

• Journal of Embryo Transfer
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• v.27 no.1
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• pp.15-20
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• 2012

The objective of this study was to investigate the relationship between body weight, body condition score (BCS), blood urea nitrogen (BUN), glucose, cholesterol and number of transferable embryos for the purpose of improving reproductive performance in Hanwoo donors. Seventy five cows, at random stages of the estrous cycle, received a CIDR together with injection of 1mg estradiol benzoate and 50 mg progesterone, and gonadotropin treatment begann. Four days later, the animals were superovulated with a total of 28AU FSH (Antorin, 2AU = 1 ml) administered twice daily in constant doses over 4 days. On the 3rd administration of FSH, CIDR was withdrawn and 25 mg $PGF_2{\alpha}$ was administered. Cows were artificially inseminated twice after estrous detection at 12 hr intervals. The cows received $100{\mu}g$ GnRH at the time of 1st insemination. Embryos were recovered 7 days after the 1st insemination. In conclusion, cows with body weight < 400, 400~450 and > 450kg had number of transferable embryos of $4.2{\pm}1.7$, $6.1{\pm}2.7$ and $4.8{\pm}2.6$, cows with BCS <2.25, 2.25~2.75 and ${\geq}2.75$ had number of transferable embryos of $4.6{\pm}1.6$, $5.7{\pm}2.4$ and $5.1{\pm}2.7$ respectively. These data indicate that a body weight and BCS for superovulation of CIDR-treated Korean native cows does not affect the embryo yield.

• Clinical and Experimental Reproductive Medicine
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• v.25 no.2
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• pp.141-151
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• 1998

Objectives: To determine whether the body weight, body mass index (BMI), and basal serum level of LH, FSH, testosterone (T), dehydroepiandrosterone sulfate (DHEA-S) are related to the ovarian response to clomiphene citrate (CC) in patients with polycystic ovarian syndrome (PCOS). Materials and Method: From January 1996 to June 1997, total 57 patients with PCOS were enrolled in the present study. Women who had other infertility factors were excluded from our study. The ovulation induction using CC was used in all patients. The patients were grouped into 50 mg group, 100 mg group, and 150 mg group according to their daily CC dose. The patients were also grouped to ovulatory and non-ovulatory group. The body weight, BMI, and basal serum level of LH, FSH, T, DHEA-S were measured in all patients on the 2nd or 3rd day of the menstrual cycle. Results were analysed with Student's t-test and Fisher's exact test. Results: The body weight and BMI of the nonovulating group were significantly higher than those of the ovulating group in all groups (50, 100, 150 mg of CC). However, there were no significant differences of the level of LH and FSH between ovulating and nonovulating groups in all CC groups (50, 100, 150 mg). The level of T of nonovulating group was significantly higher in 50 and 100 mg of CC groups, but not in 150 mg group. The level of DHEA-S of the non-ovulating group is significantly higher in 50 mg group, but not in 100 and 150 mg groups. Conclusion: The body weight and BMI could be useful predictors of ovarian response to CC in patients with PCOS, and basal T and DHEA-S also might be useful in cases of low-dose CC treatment.