• Title/Summary/Keyword: D10S

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Haplotype Analysis of BRCA1 Gene D17S855 and D17S1322 Markers in Iranian Familial Breast Cancer Patients

  • Miresmaeili, Sayed Mohsen;Tamandani, Dor Mohammad Kordi;Kalantar, Seyed Mehdi;Moshtaghiun, Seyed Mohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.7
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    • pp.3615-3617
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    • 2016
  • Background: Breast cancer molecular analysis by linkage analysis has the advantage of facilitating early diagnosis in asymptomatic genetic carriers, with a view to the preventive follow-up of these subjects and genetic counseling. The aim of this study was to evaluate BRCA1 gene D17S855 and D17S1322 markers in breast cancer patients. Materials and Methods: A series of 85 BC patients and 85 unrelated healthy women were recruited for haplotype analysis performed using two short tandem repeat markers located within the BRCA1 gene locus. Each marker was amplified with PCR genomic DNA from each individual and fluorescently end-labeled primers. Results: Both D17S855 and D17S1322 markers included 12 kinds of alleles. Results indicate that most of the BC patients shared two common 121-150 (11.2%, RR=1.56 and p=0.02) and 121-146 (5.6%, RR=1.9 and p=0.02) haplotypes. Conclusions: Our results should be helpful to understand the haplotype phase in the BRCA1 gene and establish a genetic screening strategy in the Iranian population.

Star formation history of dwarf elliptical-like galaxies

  • Seo, Mira;Ann, Hong Bae
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.54.3-55
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    • 2018
  • We present the physical and environmental properties of nearby dwarf elliptical-like galaxies. The present sample consists of ~ 1,100 dwarf elliptical-like galaxies within redshifts 0.01. The morphological types of the present study were determined by Ann, Seo, and Ha (2015) who classified the dwarf elliptical-like galaxies by the five subtypes of dS0, dE, dSph, dEbc, and dEblue. We examine their star formation history using STARLIGHT. The star formation history of dwarf elliptical-like galaxies depends on their subtypes. The luminosities of dS0, dE, and dSph galaxies are dominated by the extremely old stars (${\geq}10^{10}yr$) with $z{\approx}0.0004$ while those of dEbc and dEblue galaxies are mainly due to the young (${\sim}10^7yr$) stars together with the nearly equal contribution by extremely young stars (${\sim}10^6yr$) and old (${\sim}10^9yr$) stars. Young populations have a variety of metallicity, from z=0.0001 to z = 0.04, while old populations have metallicity of z = 0.0001 and z = 0.0004. While the formation history of stars older than ~1010yr depends mainly on the luminosity of galaxies, the formation history of stars younger than ~108yr is mainly affected by their environment. However, luminosity and environment are equally important for the star formation history if there is no star formation at the early phase of galaxy formation.

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(AlGaAs/GaAs HBT IC Chipset for 10Gbit/s Optical Receiver) (10Gbit/s 광수신기용 AlGaAs/GaAs HBT IC 칩 셋)

  • 송재호;유태환;박창수;곽봉신
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.36C no.4
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    • pp.45-53
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    • 1999
  • A pre amplifier, a limiting amplifier, and a decision IC chipset for 10Gbit/s optical receiver was implemented with AIGaAs/GaAs HBT(Heterojunction Bipolar Transistor) technology. The HBT allows a cutoff frequency of 55GHz and a maximum oscillation of 45GHz. An optical receiver front-end was implemented with the fabricated pre amplifier IC and a PIN photodiode. It showed 46dB$\Omega$, gain and $f_{3db}$ of 12.3GHz. The limiting amplifier Ie showed 27dB small signal gain, $f_{3db}$ of 1O.6GHz, and the output is limited to 900mVp-p from 20mVp-p input voltage. The decision circuit IC showed 300-degree phase margin and input voltage sensitivity of 47mVp-p at 1OGbit/s.

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Design of a Current Steering 10-bit CMOS D/A Converter Based on a Self-Calibration Bias Technique (자가보정 바이어스 기법을 이용한 Current Steering 10-bit CMOS D/A 변환기 설계)

  • Lim, ChaeYeol;Lee, JangWoo;Song, MinKyu
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.10
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    • pp.91-97
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    • 2013
  • In this paper, a current steering 10-bit CMOS D/A converter to drive a NTSC/PAL analog TV is proposed. The proposed D/A converter has a 50MS/s operating speed with a 6+4 segmented type. Further, in order to minimize the device mismatch, a self-calibration bias technique with a fully integrated termination resistance is discussed. The chip has been fabricated with a 3.3V 0.11um 1-poly 6-metal CMOS technology. The effective chip area is $0.35mm^2$ and power consumption is about 88mW. The experimental result of SFDR is 63.1dB, when the input frequency is 1MHz at the 50MHz of sampling frequency.

Mortality Analysis of Open Heart Surgery (75 Cases) (개심수술후의 사망예에 대한 임상적 고찰)

  • 김광택
    • Journal of Chest Surgery
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    • v.13 no.3
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    • pp.167-173
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    • 1980
  • From 1976 through June 1980, 75 patients underwent Open heart operation at Korea University Hospital.Of the 75 patients, 39 were congenital heart cases and 36 were acquired heart disease cases. 39 cases of congenital heart disease were consisting of 16 T.O.F.,4 A.S.D., 10 V.S.D., 3 P.S., 1 P.D.A., 1 V.S.D. + Mi, 1 Truncus arteriosus, 1 Ebstein, 1 D.C.R.V., 1 Single ventricle. Among 36 valvular replacement cases, 18 cases of MVR, 3 cases of AVR, 6 cases of Double valve replacement, and 10 cases of Open Mitral commissurotomy, were performed. Postoperative mortality rate of congenital heart disease was 25.6% and that of acquired heart disease was 8.3%. Overall mortality rate of open heart surgery was 17.3%. Among 16 cases of postoperative death cases, 5 cases of autopsy were performed. Postoperative cause of death of our series were intracranial bleeding, pacemaker failure, low output syndrome, protamine anaphylaxis, bleeding, prosthetic valve embolism, C V A, miliary tuberculosis, hypothermia due to pump failure.

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CAE Solid Element Mesh Generation from 3D Laser Scanned Surface Point Coordinates

  • Jarng S.S.;Yang H.J.;Lee J.H.
    • Korean Journal of Computational Design and Engineering
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    • v.10 no.3
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    • pp.162-167
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    • 2005
  • A 3D solid element mesh generation algorithm was newly developed. 3D surface points of global rectangular coordinates were supplied by a 3D laser scanner. The algorithm is strait forward and simple but it generates hexahedral solid elements. Then, the surface rectangular elements were generated from the solid elements. The key of the algorithm is elimination of unnecessary elements and 3D boundary surface fitting using given 3D surface point data.

Interactive Super Multi-view Content Technology (인터랙티브 초다시점 콘텐츠 제작 기술)

  • Cheong, J.S.;Ghyme, S.;Heo, G.S.;Jeong, I.K.
    • Electronics and Telecommunications Trends
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    • v.32 no.5
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    • pp.39-48
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    • 2017
  • Since the world's first 3D commercial film with red-blue glasses was introduced in 1922, remarkable progress has been made in the field of 3D video. 3D video content gained enormous popularity with the movie "Avatar," which greatly increased the sale of 3D TVs. This momentum has weakened owing to lack of 3D content. However, the recent trend of virtual reality (VR) and augmented reality (AR) made 360 VR video and 3D games using a head mounted display wide spread. All these experiences mentioned above require wearing glasses to enjoy 3D content. Super multi-view content technology, on the other hand, enables viewers to enjoy 3D content without glasses on a super multi-view display. In this article, we introduce the technologies used to make super multi-view content, interact with it, and author content, which are developed by ETRI.

Analysis on the Interference Effects between HAPS and NGSO Systems in the Feeder Link (HAPS와 NGSO 시스템간의 Feeder Link상의 간섭분석)

  • Kang, Young-Heung;Mun, Seung-Young
    • Journal of Advanced Navigation Technology
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    • v.4 no.2
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    • pp.182-190
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    • 2000
  • In this paper, interference effects between NGSO and HAPS in the feeder link have been simulated and analyzed by means of calculating excess time percent and duration below the ell protection ratio. As the results, in the case of HAPS interference into NGSO, it can be obtained that the lowest C/I values are 20.42dB in 50km and 12.73dB in 20km of HAPS altitudes, respectively. And in the case of NGSO interference into HAPS, it can be obtained that the lowest ell values are 13.94dB and 10.42dB respectively. HAPS system has more interference reception from other systems or effects more interference into other systems as its altitude is lower. Also, the lowest ell values are appeared at difference time with its altitude.

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Analysis on the Interference Effects between HAPS and NGSO Systems in the Feeder Link (HAPS와 NGSO 시스템의 Feeder Link상의 간섭분석)

  • 문승영;김봉석;강영흥
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2000.11a
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    • pp.34-38
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    • 2000
  • In this paper, interference effects between NGSO and HAPS in the feeder link have been simulated and analyzed by means of calculating excess time percent and duration below the C/I protection ratio. As the results, in the case of HAPS interference into NGSO, it can be obtained that the lowest C/I values are 27.42dB in 50km and 12.73dB in 20Km of HAPS altitudes, respectively. And in the case of NGSO interference into HAPS, it can be obtained that the lowest C/I values are 13.94dB and 10.42dB respectively. HAPS system has more interference reception from other systems or effects more interference into other systems as its altitude is lower. Also, the lowest C/I values are appeared at difference time with its altitude.

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Changes of Nitrogen Compounds and Nutritional Evaluation of Soybean Sprout -Part VI. Changes in electrophoretic pattern of protein- (콩나물 제조중(製造中) 질소화합물(窒素化合物)의 변화(變化)와 그 영양학적(營養學的) 연구(硏究) -제육보(第六報). 단백질(蛋白質)의 전기영동양상변화(電氣泳動樣相變化)-)

  • Yang, Cha-Bum;Park, Sang-Ki;Yoon, Suk-Kwon;Park, Hoon
    • Applied Biological Chemistry
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    • v.27 no.2
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    • pp.129-134
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    • 1984
  • Change of protein component in soybean sprout grown at four temperatures was investigated by polyacrylamide gel electrophoresis. Main bands were identified using purified seed globulins. Electrophoretogram showed 5 main bands (a. b, c, d, and p) and 10 minor bands in seed and maximum number (19) of bands (8 main band including 0 and 11 minor) at 4th day after germination in cotyledon. All bands appeared in axis protein but resolution was poor. In cotyledon, a component (most rapidly) and b+c+d component decreased while o+p component and other minor components were increased at 6th day and decreased thereafter. In axis all components increased rapidly, especially in minor components and b+c+d component. High growing temperature accelerated decrease in cotyledon and increase in axis of protein, especially for 11S. The a component was identified as 7S, b+c+d as 11S and o+p as 2S globulin.

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