• Journal of Plant Biology
• /
• 제37권4호
• /
• pp.441-444
• /
• 1994

강낭콩(Phaseolus vulgaris L.) 미숙종자로부터 신규 phytosteryl glucoside를 순수분리하였다. 이 화합물은 positive FAB-MS에서 m/z 613에 $[M+Na]^{+}$를, 696에 $[M+Matrix]^{+}$의 강한 ion peak를 나타내었고, negative FABMS에서 m/z 589에 $[M-1]^{-}$의 강한 ion peak를 나타내어 그 분자량은 590으로 확인되었다. 400 MHz $^1H-NMR$ 분석 결과 이 화합물은 24-hydroxy-24-vinyl-cholesterol(saringosterol)과 ${\beta}-D-glucopyranose$가 연결되어 있는 saringosteryl glucoside임을 알 수 있었고, 이 화합물의 acetyl화 화합물의 400 MHz $^1H-NMR$의 분석을 통하여 이 화합물은 saringosterol의 C-3 수산기와 ${\beta}-D-glucopyranose$의 C-1'의 수산기가 탈수축합되어 있는 $3-O-{\beta}-D-glucopyranosyl-24-hydroxy-24-vinyl-cholesterol$(saringosteryul glucoside)로 구조결정되었다. 이 saringosteryl glucoside는 천연으로부터 처음 동정된 신규 화합물이며, 이 화합물의 aglycone인 saringosterol도 고등 식물에서는 처음으로 발견된 것이다.

• 생약학회지
• /
• 제27권4호
• /
• pp.366-370
• /
• 1996

Fruits of Rubus coreanum (Korean name: Bog-bun-ja) have been used in oriental traditional medicine as the remedies for impotence, pollution, premature ejaculation and frequency of urination etc. It is known to have phenolic compounds as an astringent. By means of chromatographic methods, four hydrolyzable tannins were isolated from the fruits of R. coreanum. The structures of these compounds were established as gallic acid, 2,3(S)-HHDP-D-glucopyranose, sanguiin H-4 and sanguiin H-6 on the basis of physicochemical and spectroscopic evidences.

• Preventive Nutrition and Food Science
• /
• 제12권2호
• /
• pp.119-121
• /
• 2007

The tyrosinase inhibition activity and mutagenicity as assessed by the Ames test on phenolic antioxidants (5-Caffeoyl quinic acid, 3,4-Dihydroxy cinnamic acid, Quercetin 3-O-${\beta}$-D-glucopyranose, Kaempferol 3-O-${\beta}$- D-glucopyranose) and the ethyl acetate fraction isolated from mulberry leaves were examined. The ethyl acetate fraction and chlorogenic acid exhibited weaker tyrosinase inhibitory activities than kojic acid. In addition, the ethyl acetate fraction from mulberry leaves, containing phenolic antioxidants, showed no mutagenicity by the Ames test.

• 한국섬유공학회:학술대회논문집
• /
• 한국섬유공학회 2003년도 가을 학술발표회 논문집
• /
• pp.277-278
• /
• 2003

키틴은 셀룰로오스와 더불어 자연계에 가장 많이 존재하는 천연고분자(선형다당)로서 $\beta$(1$\longrightarrow$4)-2-deoxy-2-acetamido-D-glucopyranose를 기본단위로 하고, 키토산(chitosan)은 천연적으로는 몇몇 미생물에서 발견되며, 키틴의 탈아세틸화반응(deacetylation)에 의해 생성되는 유도체로서 $\beta$(1$\longrightarrow$4)-2-deoxy-2-amino-D-glucopyranose를 기본단위로 한다는 점에서 상이하다. 하지만 키틴과 키토산은 각 기본단위가 반복된 homopolymer가 아니고 서로 일정 정도의 상대 기본단위를 함유하므로 일종의 공중합체 또는 heteropolymer라고 할 수 있으며, 그 조성비 즉 탈아세틸화도 (degree of deacetylation, 이하 DD)에 따라 키틴과 키티산으로 나누어진다.[1] (중략)

• Archives of Pharmacal Research
• /
• 제18권2호
• /
• pp.118-120
• /
• 1995

The cytotoxicity-directed fractionation of MeOH extract of Terminalia chebula fruits led to the isolation of three hydrolyzed tannins and a related compound, gallic acid(1), $1,2,3,4,6-penta-O-galloy-{\beta}-_D/-glucopyranose(II)$,. chebulagic acid (III) and chebulinic acid(IV), as active principles. They were shoen to exhibit moderate cytotoxicity against cultured human tumor cell lines including A-549, SK-OV-3, Sk-MEL-2, XF-498 and HCT-15 in vitro.

• Natural Product Sciences
• /
• 제17권4호
• /
• pp.279-284
• /
• 2011

Phytochemical studies on the whole extract of Sedum hybridum L., a Mongolian medicinal plant, has been undertaken to isolate active principles responsible for its anti-oxidative and antibacterial activities. Eighteen known compounds, i.e. (1) quercetin, (2) kaempferol, (3) herbacetin-8-O-${\beta}$-D-xylopyranoside, (4) myricetin, (5) gossypetin-8-O-${\beta}$-D-xylopyranoside, (6) gallic acid, (7) 2,4,6-tri-O-galloyl-D-glucopyranose, (8) 6-O-galloylarbutin, (9) myricetin-3-O-${\alpha}$-L-arabinofuranoside, (10) quercetin-3-O-${\alpha}$-L-arabinofuranoside, (11) caffeic acid, (12) ethylgallate, (13) (-) epigallocatechin-3-O-gallate, (14) palmitic acid, (15) stearic acid, (16) stearic acid ethyl ether, (17) ${\beta}$-sitosterol and (18) ${\beta}$-sitosteryl-O-${\beta}$-D-glucopyranose have been isolated and their molecular structures identified by spectroscopic analysis. Thirteen substances including seven flavonol components (1, 2, 3, 4, 5, 9 and 10), five gallic acid derivatives (6, 7, 8, 12 and 13) and caffeic acid (11) exhibited significant, dose-dependent, DPPH radical scavenging activity. Galloyl esters 12 and 13 were revealed to be main active principles for the antibacterial property of the extract of Sedum hybridum L.

• Journal of Microbiology and Biotechnology
• /
• 제10권2호
• /
• pp.267-271
• /
• 2000

Abstract Two glucans (PONGa and PONGb) differing in their anomeric and glycosidic linkage structures were isolated from the water-insoluble materials (PON) of Pleurotus ostreatus basidiocarps, which activated the complement system and were almost soley composed of D-glucose. The isolatIon was achieved by repeated precipitations with ethanol and adsorption on concanavalin A (Con A) of paN suspension in thymol/NaCL Based on methylation analysis. IR, GLC-MS, $^1H,{\;}and{\;}^{13}C-NMR$ spectroscopies, PONGa was found to be a branched a-glucan composed of ${\alpha}-linked$ D-glucopyranose residues and ${\alpha}-linked$ units with 6-branching points, whereas PONGb was a linear ${\beta}-1,3-glucan$ composed mainly of ${\beta}-1,3-linked$ D-glucopyranose residues. The PONGb particles reacted more potently than the PONGa particles as C3 activator in alternative complement hemolysis and crossed-immunoelectrophoresis using anti-human C3, thereby suggesting that the complement activating components of PON were ${\beta}-(13)-glucans rather$ than ${\alpha}-glucan$ components.onents.

• 한국섬유공학회:학술대회논문집
• /
• 한국섬유공학회 1998년도 봄 학술발표회 논문집
• /
• pp.325-328
• /
• 1998

$\beta$-cyclodextrin($\beta$-CD)은 cycloheptaamylose라고도 하며 $D^{＜+>}$-glucopyranose 단위체가 7개 연결된 구조를 가지고 있다(Fig. 1). $\beta$-CD는 고리모양으로 되어있는데 외부는 친수성, 내부는 소수성을 갖는다[1]. 고리내 부가 소수성인 이유는 내부에 소수성기인 C-H그룹과 glucosidic oxygen만이 존재하기 때문이다[1].(중략)

• Food Science and Biotechnology
• /
• 제15권4호
• /
• pp.555-558
• /
• 2006

The chemical reduction of Pseudomonas syringae subsp. phaseolicola alginates produces neutral polymers of D-mannose and L-gulose in source specific ratios. L-Gulose was highly sensitive to degradation by 1N HCl at $100^{\circ}C$. As hydrolysis time increased, gulose recovery decreased to 22% after 4 hr, whereas 98% of the D-mannose was recovered under the same conditions. Thin layer chromatography showed the formation of a second product upon L-gulose acid hydrolysis. This new product had a rate of flow (Rf) value of 0.58, identical to that of 1,6 anhydro-${\beta}$-D-mannopyranose and very close to that of 1,6 anhydro-${\beta}$-D-glucopyranose (Rf=0.60). Because of the difference in acid sensitivity between L-gulose and D-mannose, normal acid hydrolytic techniques applied to reduced alginates produces erroneous mannuronic acid (M): guluronic acid (G) ratio's unless one accounts for the differential rates of destruction of each sugar.

• Archives of Pharmacal Research
• /
• 제19권5호
• /
• pp.429-431
• /
• 1996

A new cycloartane glycoside (1) was isolated from the aerial part of Thalictrum uchiyamai Nakai (Ranunculaceae). On the basis of chemical and physicochemical evidence, the aglycone structure of this compound was characterized as 116, 25-dihydroxy-3, 24-diacetoxy-9, 19-cycloartane-29-oic acid, a new derivative of cycloartane triterpene. Also the oli-gosaccharide moiety of this glycoside were determined as 29-O-${alpha}$-L-rhanmnopyranosyl- ($1rightarrow2$)-[${beta}$-D-xylofuranosyl-($1rightarrow6$)-${beta}$-D-glucopyranose by application of HMBC technoque. Consequently, the structure of compound 1 was elucidated as 29-O-${alpha}$-L-rhanmnopyranosy-($1rightarrow2$)-[${beta}$-D-xylofuranosyl-($1rightarrow6$)-${beta}$-D-glucopyranosyl-16, 25-dihydroxy-3, 24-diacetoxy-9, 19-cycloartane-29-oic acid ester.