• Bulletin of the Korean Chemical Society
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• 제24권7호
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• pp.921-924
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• 2003

Homochiral (-)-pipecolaldehyde 6 from D-glucono- δ-lactone underwent a highly diastereoselective addition upon treatment with vinylmagnesium bromide. Treatment with vinylmagnesium bromide produced antiaminoalcohol 7a which was easily converted into the synthesis of 1,6-diepicastanospermine 2.

• Bulletin of the Korean Chemical Society
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• 제27권8호
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• pp.1211-1218
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• 2006

The enantiomerically pure (2R,3S)- and (2R,3R)-3-amino-2-hydroxy-4-phenylbutanoic acids (AHPBA) 1 and 3 are readily obtained from D-glucono-a-lactone. Both AHPBAs are the structural key units of KMI derivatives which are the potent inhibitors of BACE 1 ($\beta$-secretase) and HIV protease. Additionally, the obtained AHPBAs 1 and 3 are converted to dipeptides of bestatin stereoisomers 2 and 4.

• Bulletin of the Korean Chemical Society
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• 제19권12호
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• pp.1369-1372
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• 1998

The (-)-polyoxamic acid 2 and its stereoisomer 3 have been prepared from D-glucono-δ-lactone which has three available stereocenters as required for 2 and 3. Key transformations included the selective cleavage of the terminal isopropylidene group.