• Journal of Korean Ophthalmic Optics Society
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• v.7 no.2
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• pp.163-167
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• 2002

Improved optical switching property of electrochromic nickel hydroxide/nickel glass thin film is reported. Nickel metal film was deposited on glass by e-beam evaporation before following electrochemical redox cycling to form nickel hydroxide for electrochromic activation. Without ITO (indium tin oxide) layer as electrical conductor, this electrode showed more rapid coloration rate than nickel hydroxide film on ITO substrate in the change of the electric voltage and optical transmittance. XPS analysis confirmed the existence of ultra-thin nickel metal layer (${\sim}10{\AA}$) between electrochemically grown nickel hydroxide and the glass substrate. It is concluded that the remained nickel metal nano-layer attribute to the conduction layer and the enhanced response time.

• 한국HCI학회:학술대회논문집
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• 2006.02a
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• pp.717-722
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• 2006

경제지표, 주식시세, 전자상거래 등 시각적으로 제공되는 정보 중에 정확한 숫자가 중요한 정보인 경우도 있지만 2 차 정보로서 변화의 추세나 패턴이 중요한 경우도 있다. 주식을 포함한 유가증권이나 선물거래의 경우 주로 미국식 봉차트를 사용하는데 개인투자자가 늘고 있는 우리나라 실정으로 볼때 식음을 전폐하고 전광판에 매달리는 문제점이 지적되고 있고, 전문투자자들도 시각정보를 놓치지 않기 위해 일상 업무에 소홀해지는 경우가 많다. 이러한 경우 음향정보도 함께 제공한다면 인간은 다양한 감각기관을 가지고 있기 때문에 시각정보를 주로 이용하다가도 잠시 휴식을 취하거나 다른 용무가 있을 때 청각정보를 보완적으로 사용하여 스트레스를 줄일 수 있고 명철한 판단력을 유지할 수 있으며, 경우에 따라서는 음향정보가 상황판단을 위해 더욱 효과적일 수도 있을 것으로 본다. 음향정보가 시각정보를 대체하기 보다는 2 차 정보로서 상호보완성이 목적이라면 정확한 숫자의 표현보다는 거래패턴 등을 음악적으로 표현하여 음악 감상의 기능까지 갖춘다면 시각정보와는 차별화된 음향정보의 독자성을 찾을 수 있다. 간혹 종목별 등락을 읽어주거나 중요한 매매시점에 신호음을 내는 청각적인 방법이 사용되기도 하지만 상당히 제한적이고 단순한 상태이다. 그러므로 본 연구의 진정한 개발목적은 정보성 이외에 예술적 표현을 융합하는 것이며, 시각장애인이나 네트워크 환경이 열악한 사람들도 주식투자에 있어서 평등성을 보장하여 건전한 투자문화를 형성하기 위함이다. 실시간 거래정보를 음악적으로 표현하여 업무를 보면서도 들려오는 음악을 통해 거래상황을 파악할 수 있는 연구방법으로 거래빈도는 음의 빠르기로, 거래가는 음의 높낮이, 거래량은 음의 세기, 종목은 악기의 음색으로 표현하였으며, 컴퓨터에 내장된 사운드카드를 통해 소리를 들을 수 있도록 MIDI 데이터로 변환하였다. 통계정보는 주로 한국증권선물거래소(KRX: The Korea Exchange)에서 발췌하였으며, 시뮬레이션을 위한 프로그래밍 언어로는 Cycling74 의 Max/MSP 를 사용하였다.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5455-5461
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• 2012

Luteolin is a plant flavonoid which exhibits anti-oxidative, anti-inflammatory and anti-tumor effects. However, the antiproliferative potential of luteolin is not fully understood. In this study, we investigated the effect of luteolin on cell cycling and apoptosis in human esophageal squamous carcinoma cell line Eca109 cells. MTT assays showed that luteolin had obvious cytotoxicity on Eca109 with an $IC_{50}$ of $70.7{\pm}1.72{\mu}M$ at 24h. Luteolin arrested cell cycle progression in the G0/G1 phase and prevented entry into S phase in a dose- and time-dependent manner. as assessed by FCM. Luteolin induced apoptosis of Eca109 cells was demonstrated by AO/EB staining assay and annexin V-FITC/PI staining. Moreover, luteolin downregulated the expression of cyclin D1, survivin and c-myc, and it also upregulated the expression of p53, in line with the fact that luteolin was able to inhibit Eca109 cell proliferation.

• Journal of the Korea Fashion and Costume Design Association
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• v.18 no.2
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• pp.191-206
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• 2016

A designer representing an avant guard fashion, Martin Margiela introduces experimental collections that seek ideational and ideal values, breaking away from limits of popular universality or usefulness of fashion. This study seeks to interpret Martin Margiela's design characteristics from the perspective of ambiguity, and thereby examine theoretical basis of meaning interpretation of his ambiguous and innovative design. In poetic meaning ambiguity is verbal nuance which gives room for alternative reaction the same piece of language. By way of study methods, concepts and characteristics of ambiguity were examined based on William Empson's seven types of ambiguity, and characteristics of Martin Margiela's fashion design were analyzed from the perspective of ambiguity. In the study, expression of ambiguity in Martin Margiela's fashion design was categorized into ambiguity of forms, that of meanings, and that of existence. Ambiguity of forms could be found indeterminate form of clothes and flat clothes. Ambiguity of meaning refers to ambiguity arising from the possibility of the meaning that fashion design is going to convey diverse interpretation. Ambiguity of meaning could be found up-cycling vintage clothes, semi-couture, signs of time, unfitting size, and symbolic letter. Ambiguity of existence could be found inanimate dummy, face shrouded with a veil and expression of multiple identity. In Martin Margiela's fashion design ambiguity gives rise to joy of something fresh, amusement felt about what deviates from normality and the possibility of fashion design's endless creations.

• Korean Journal of Agricultural Science
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• v.44 no.4
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• pp.495-503
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• 2017

Genotyping-by-sequencing (GBS) is an outstanding technology for genotyping and single nucleotide polymorphism (SNP) discovery compared to next generation sequencing (NGS) because it can save time when analyzing large-scale samples and carries a low cost per sample. Recently, studies using GBS have been conducted on major crops and, to a greater extent, on fruit crops. However, many researchers have some problems due to low GBS efficiency resulting from low quality GBS libraries. To overcome this limitation, we developed an efficient GBS library construction method that regulates important conditions such as restriction enzymes (RE) digestion and a PCR procedure for grapevine. For RE digestion, DNA samples are digested with ApeKI (3.6U) at $75^{\circ}C$ for 5 hours and adapters are ligated to the ends of gDNA products. To produce suitable PCR fragments for sequencing, we modified the PCR amplification conditions; temperature cycling consisted of $72^{\circ}C$ (5 min), $98^{\circ}C$ (30 s), followed by 16 cycles of $98^{\circ}C$ (30 s), $65^{\circ}C$ (30 s), $72^{\circ}C$ (20 s) with a final extension step. As a result, we had obtained optimal library construct sizes (200 to 400 bp) for GBS analysis. Furthermore, it not only increased the mapping efficiency by approximately 10.17% compared to the previous method, but also produced mapped reads which were distributed equally on the19 chromosomes in the grape genome. Therefore, we suggest that this system can be used for various fruit crops and is expected to increase the efficiency of various genomic analysis performed.

• Journal of the Korean Wood Science and Technology
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• v.46 no.2
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• pp.166-177
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• 2018

Plant essential oils are defined as fragrant volatile oils extracted from leaves, stems, fruits, flowers, and roots of a plant. Such oils are composed of multiple components and multiple functions. By accumulation of inductive information, various plant essential oils have been studied for using in therapeutic medicine for various diseases. Despite of the apparent advantages of essential oils as a source of therapeutic medicines, plant essential oils have many limitations, including cytotoxic side effects. Therefore, it is necessary to evaluate the toxicity and the mechanisms of cytotoxicity of such oils. In this study, we evaluated the cytotoxicity to human-derived cell lines of 10 plant essential oils provided by National Institute of Forest Science (i.e., Larix kaempferi; Abies holophylla; Zanthoxylum ailanthoides; Pinus parviflora; Tsuga sieboldti; Chamaecyparis pisifera; Cryptomeria japonica; Pinus densiflora; Illicium anisatum; Pinus thunbergii). Cytotoxicity evaluations were accomplished by using CCK-assays and PCR-based cytotoxicity-related marker gene analyses with A549 cell line, and the Detroit551 cell line which are lung and skin cell line. The genes were analyzed included caspase-3 has a role in cell apoptosis, and the other cyclinA, cyclinB, cyclinD, and cyclinE regulated cell cycling for the cell proliferation. By examining the five cytotoxicity-related marker genes by performing real-time PCR and examined the cytostatic gene regulation associated with the various essential oils. The results of this study showed that the degree of cytotoxicity and the cytostatic gene regulation which could give precious information for using the plant essential oil for the clinical usages.

• The Research Journal of the Costume Culture
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• v.7 no.6
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• pp.98-115
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• 1999

As sports infiltrates each field of modern society and becomes familiar, sports wear was changed functionally and was introduced and enveloped into everyday dress. Modern sports wear has been the settled in everyday life deeply and become the clothes of life which are worn regardless of place, time and age. The aim of this paper was to clarify what kind of fashion of sports style would be given to the modern people. In this study, sports wear which has become everyday dress classified from a gender point of view. It was divided into masculine image, feminine image, and neutral image. Sports wear of masculine image generated a silhouette which emphasized the shoulder with the aspiration for youth and health. Wide shoulder was considered as the symbol of masculine beauty and the expression of healthy beauty. It was reflected well in body conscious look. And owing to the development of up-to-data materials, innovation of design, and the study of human body technology, the functional character was settled in the sports wear which showed masculine image. Sports wear of feminine image was represented fashion of body exposure, body feet with body conscious look, and romantic mode. This image was expressed fashion as comforts, pleasant, active design, materials, color, and romantic feminine beauty. Sports wear of neutral image was expressed into unisex clothes. This cloths have no difference in gender, age, and class. It was used as casual sports wear. In the 1960s, young generation participated in such street sports as street basketball and skate. They usually sore the sports wears of neutral image such as cycling, skating, and ski. In the materials of sports, the development of up-to-data material like lycra made the sayings lifelike, “up-to-data material is the second skin” It show that glamorous feminine image and strong masculine image coexisted. The contemporary concept of sportswear is no longer limited to those clothes for sports found in such places like tennis court or swimming pool. Now, the sports wear become more like casual activity wear all classes of people can enjoy in their life regardless of where they are, when they wear, and even how old they are.

• Restorative Dentistry and Endodontics
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• v.16 no.2
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• pp.33-42
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• 1991

The purpose of this study was to evaluate the sealing properties of the temporary filling materials used in endodontic treatment Access cavities were prepared in 135 extracted human molar teeth. Then, cotton pellets were placed in the pulp chamber until the depth of 5 mm for the temporary filling materials; Caviton, zine oxide-eugenol, double sealing (A) (stopping 15 mm + zinc oxide - eugenol, 3.5mm ) double sealing (B) (stopping 3.0 mm + zinc oxide - eugenol 2.0 mm) and gutta percha stopping. After filling the materials, the teeth were immersed in 1 % methylene blue solutions for 3 days, 1 week and 2 weeks. Then thermal cycling was performed at the temperature of $60^{\circ}C$ and $4^{\circ}C$, followed by longitudinal sections on the center of tooth. Finally, staining on the cotton pellet was evaluated. The following results were obtained. 1. Stopping showed lower marginal sealing quality than Caviton, zinc oxide - eugenol and double sealing. 2. In 1 week group, Caviton showed higher marginal sealing quality than zinc oxide-eugenol, double sealing and stopping. 3. Caviton and double sealing (B) showed a great decrease in marginal sealing quality with the increse of time. 4. Caviton had high marginal sealing quality in 3 day group and 1 week group, but in 2 week group, Caviton showed a great decrease. 5. Double sealing (B) showed fairly high marginal sealing quality in 3 day group, but decreased greatly after 1 week on.

• Journal of Pharmaceutical Investigation
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• v.22 no.4
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• pp.289-300
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• 1992

The counter-transport phenomena in the hepatic transport of 1-anilino-8-naphthalene sulfonate (ANS) were kinetically investigated by analyzing the plasma disappearance-time profiles and the transport into the isolated hepatocytes. In vivo "counter transport phenomena" were simulated based on the perfusion model which incorporated the carrier-mediated transport and the saturable intracellular binding. The condition that the mobility of carrier-ligand complex is greater than that of free carrier is not essential for the occurrence of counter-transport phenomenon. To examine the inhibitory effects on the initial uptake of a ligand by the liver, it is necessary to judge whether the true counter-transport mechanism (trans-stimulation) is working or not. The initial plasma disappearance curves of ANS were then kinetically analyzed based on a two-compartment model, in which the ligand is eliminated only from the peripheral compartment (liver compartment). No effects on the initial plasma disappearance rates of ANS were observed after preloading of bromophenol blue (BPB) or rose bengal (RB) in the liver. Inhibitory effect of BPB or RB on the initial uptake (or efflux) rates of ANS by the isolated hepatocytes were not observed, suggesting that the true counter transport mechanism is not working. In conclusion, checking the preloading effects of transstimulation on the initial uptake of a ligand by the liver could be a useful criterion for carrier cycling and common use of the same carrier between two ligands. However, one cannot exclude those possibilities even if the preloading effects cannot be observed.

• Progress in Superconductivity
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• v.13 no.2
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• pp.105-110
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• 2011

SQUID sensor-based ultra low-field magnetic resonance apparatus with ${\mu}T$-level measurement field requires a strong prepolarization magnetic field ($B_p$) to magnetize its sample and obtain magnetic resonance signal with a high signal-to-noise ratio. This $B_p$ needs to be ramped down very quickly so that it does not interfere with signal acquisition which must take place before the sample magnetization relaxes off. A MOSFET switch-based $B_p$ coil driver has current ramp-down time ($t_{rd}$) that increases with $B_p$ current, which makes it unsuitable for driving high-field $B_p$ coil made of superconducting material. An energy cycling-type current driver has been developed for such a coil. This driver contains a storage capacitor inside a switch in IGBT-diode bridge configuration, which can manipulate how the capacitor is connected between the $B_p$ coil and its current source. The implemented circuit with 1.2 kV-tolerant devices was capable of driving 32 A current into a thick copper-wire solenoid $B_p$ coil with a 182 mm inner diameter, 0.23 H inductance, and 5.4 mT/A magnetic field-to-current ratio. The measured trd was 7.6 ms with a 160 ${\mu}F$ storage capacitor. trd was dependent only on the inductance of the coil and the capacitance of the driver capacitor. This driver is scalable to significantly higher current of superconducting $B_p$ coils without the $t_{rd}$ becoming unacceptably long with higher $B_p$ current.