• 한국패션뷰티학회지
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• 제3권1호
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• pp.50-60
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• 2005

This research analyzes whether affected some South Korea woman's hair style comparing change of West woman's head form after the mid-1940s. This research purpose is analyze effect that examine South Korea woman and West woman's hair style and compare change special quality and get in our country hair style until 1980 after the mid-1940s. This dissertation is literature research that analyze change process of West woman's hair style and South Korea woman's hair style. Investigation method utilized dress and its ornaments connection books and treatise, beauty art connection books and treatise such as the South Korea and western dress and its ornaments. The following is the chronological analysis of the influence the western hairstyle has had on the Korean women. The hairstyles in Korea have been profoundly influenced by the western culture, especially the western makeup styles and hairstyles. Therefore, exploration of the western hair and makeup-styling conveys a great significance in conducting researches on the Korean hairstyles. Conclusion of this research is hair style of our country received much effects from make-up culture specially Occidentalism, hair style culture by each age, European beauty art culture research can assume that scientific analysis of west woman's clothes and make-up is important in our country hair style research. In the future, it is believed that the cycle of changes in hair-styling will get remarkable shortened with the advance in the computer technology, which enables the world to have a much faster access to other cultures over the Internet.

• 한국디지털건축인테리어학회논문집
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• 제10권3호
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• pp.19-28
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• 2010

The construction projects are recently having changes in their magnitude and complexity. Therefore, the amount of information created and managed by participants over project phases is enormous and this may cause difficulties in consistent and integrated data management. Because of the change in construction projects, there is a need to apply more logical and systematic ways to deal integrated data management. For the solution to this, BIM(Building Information Modeling), a new paradigm for integrated management of the information over project life-cycle, has been seriously considered. Also, the Korean Public Procurement Service announced that project over 50 billion Korean Won should introduce BIM into procurement starting from 2012. However, the studies and development have lack on studies of applying BIM and managing the data made using BIM in pre-design and maintenance stage. In pre-design stage, the concept of schematic design model is made to support for making major decisions concerning the size, shape and cost of the project. To decide the cost for the building in this stage by making use of BIM, estimating the amount of building materials used for constructing should be preceded. In this study, the pre-design BIM is explained to gain a better understanding of its process, since this paper focused on space programming stage. Finally, the paper suggests the concept process of estimating the amount of materials in building interior finishing from selecting the type for the elements of each space made to support the client for making decisions in space programming stage based on pre-design BIM.

• Journal of Radiation Protection and Research
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• 제21권1호
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• pp.27-39
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• 1996

DUPIC핵연료주기로 인해 변화되는 경수로 사용 후 핵연료 물질의 핵종별 농도, 방사능, 붕괴열, 위해지수 및 방사선원항등을 시간의 함수로 그 변화특성을 분석하고, 각 인자별로 크게 영향을 미치는 주요핵종의 거동을 물질농도 측면에서 추적 분석평가하였다. 방사성물질 농도에 있어서 연소도 19,000 MWD/MTU의 사용 후 DUPIC핵연료에 존재하는 악티나이드 양은 연소도 35,000 MWD/MTU의 경수로 사용후 핵연료에 비해 약 2% 감소한 반면 핵분열생성물의 양은 약 20% 증가된 것으로 나타났다. 그리고 사용 후 DUPIC핵연료의 방사능 및 붕괴열은 일반적인 사용후핵연료 특성과는 달리, 방사성물질 농도 변화와 비례하지 않는 것으로 나타났다. 사용후 DUPIC핵연료가 갖는 감마 스펙트럼을 경수로핵연료의 경우와 비교해 볼 때, 전체적인 특징은 사용후 DUPIC핵연료의 경우가 $0.01{\sim}0.575MeV$의 낮은 에너지 범위에서는 경수로핵연료 보다 약 $40{\sim}50%$ 낮은 감마선 세기를 보여주고 있으나, 3.5 MeV이상의 높은 에너지 범위에서는 사용후 DUPIC핵연료의 감마선 세기가 휭씬 크게 나타났다. 중성자 선원항은 모두 악티나이드 물질의$({\alpha},\;n)$ 반응 및 자발핵분열에 의해 결정되고 있고, 특히 Cm-244의 자발 핵분열에 의한 중성자선원이 지배적인 것으로 나타났다. 이런 이유 때문에 Cm-244의 농도가 약 3.3배 큰 사용후 DUPIC핵연료의 중성자 선원이 경수로핵연료보다 4배 이상 크게 나타났다.

• 생명과학회지
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• 제18권1호
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• pp.75-83
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• 2008

인체 DNA topoisomerase는 DNA를 단일 또는 두 가닥을 일시적인 절단을 촉매하여 DNA의 topological 문제를 조절함으로써, DNA 복제, 전사, 재조합과 유사분열 과정 등에 관여한다. 이 효소는 많은 항생, 항암제의 표적효소로서 널리 알려져 있으며, 이들 유도체를 이용한 다양한 억제제의 개발과 임상적 응용에 관한 연구가 활발하게 진행되고 있다. 본 실험에서는 인체 백혈병 HL-60 세포에서 topoisomerase 억제제가 topoisomerase 기능 활성과 유전자 발현을 조절하는지를 규명하기 위하여 본 연구를 수행하였다. 연구 방법은 HL-60세포에 topoisomerase type I과 type II의 대표적 억제제인 10-hydroxycamptothecin (10-CPT)과 doxorubicin을 투여한 후 total RNA를 분리하였고, 10K-oligo-nucleotide microarray 방법으로 분석하여 유전자의 발현 양상을 조사하였다. 연구 결과에 의하면 10-CPT 또는 doxorubicin을 투여한 HL-60세포에서의 유전자 발현 양상은 주로 signal transduction, cell adhesion, cell cycle, cell growth, cell proliferation, cell differentiation, transcription 및 immune response 등과 관련이 있었다. Topoisomerase type I의 억제제인 10-CPT를 HL-60 세포주에 투여 하였을 때 type I으로 분류되는 topoisomerase III${\alpha}$, III${\beta}$ 및 I의 발현은 증가하였으나 type II인 topoisomerase II${\alpha}$와 II${\beta}$의 유전자의 발현은 감소되었다. 반대로 type II의 억제제인 doxorubicin을 투여하였을 때는 앞의 결과와 상반된 topoisomerase II${\alpha}$와 II${\beta}$의 유전자의 발현이 현저히 증가되었으며, topoisomerase III${\alpha}$와 III${\beta}$의 mRNA의 발현은 약간 감소하는 양상을 보였으나 의미 있는 차이는 없었다. 이 연구 결과는 앞으로 항암제의 기전을 밝히고 약물에 대한 치료 반응을 예측하고 새로운 약제 개발에 기초자료가 될 것으로 여겨진다.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2010년도 추계학술대회 초록집
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• pp.134-134
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• 2010

Recently, the interest of the study about IGCC(Integrated Gasification Combined Cycle), one of New & Renewable Energy technologies, bas been increased due to the United Nations Framework Convention on Climate Change, the Low Carbon Green Growth policy, etc. Also, with this interest of IGCC, the study on the gas turbine utilizing the synthetic gas is performing actively. In the study of the gas turbine characteristic, the power performance and the combustion efficiency are mainly discussed and also the concern about the exhaust gas is being taken care of due to the increasing awareness of the environment. With this, we would like to go over the exhaust gas emission characteristic by the synthetic gas inflow in this test. In order to conduct such a test, we constructed a synthetic gas supplying system to supply the synthetic gases ($H_2$: hydrogen, $N_2$: nitrogen, CO: carbon monoxide, $CO_2$: carbon dioxide, and $H_2O$: steam) quantitatively and this combustion test was conducted by controlling the supplied synthetic gases artificially. The concentration of the exhaust gases appeared variously depending on the differences of the inflow nitrogen amount and the steam amount, whether or not the carbon dioxide flow in and so on. The results of the test can be able to be utilized for the IGCC study by understanding the exhaust gas emission characteristic of the coal gas turbine by synthetic gas composition.

• 한국콘텐츠학회논문지
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• 제15권7호
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• pp.128-137
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• 2015

정보통신(IT) 분야는 변화가 빠르게 진행되었다. 많은 혁신제품이 출시되고, 일부는 안정적으로 시장을 형성하여 확산되지만, 일부는 사라져 버린다. 본 연구에서는 스마트기기 간 시간의 경과에 따른 경쟁요인을 도출하였다. 혁신확산이론(IDT)의 혁신채택단계를 산업수명주기이론(ILC)의 산업수명주기에 적용하여 도입기, 성장기, 성숙기의 3단계로 구분하여 시간의 흐름에 따른 시장특성 모형을 정의하였다. 노트북 컴퓨터와 태블릿 사례의 경쟁관계를 분석하여 제안된 이론적 모형의 적합도를 확인하였다. 시간의 흐름에 따라 5가지의 경쟁요인은 다르게 작용하며 도입기에는 기능성과 유희성이 중요한 경쟁요인이 되고, 성장기에는 기능성과 유희성 외에도 적합성이 추가적으로 작용함을 알 수 있었다. 마지막의 성숙기에는 적합성과 복잡성, 그리고 비용수준이 중요한 경쟁요인이었다.

• 천문학회지
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• 제36권spc1호
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• pp.83-91
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• 2003

There are terrestrial signatures of the solar activity cycle in ice core data (Ram & Stoltz 1999), but the variations in the sun's irradiance over the cycle seem too small to account for the signature (Lean 1997; Goode & Dziembowski 2003). Thus, one would expect that the signature must arise from an indirect effect(s) of solar activity. Such an indirect effect would be expected to manifest itself in the earth's reflectance. Further, the earth's climate depends directly on the albedo. Continuous observations of the earthshine have been carried out from Big Bear Solar Observatory since December 1998, with some more sporadic measurements made during the years 1994 and 1995. We have determined the annual albedos both from our observations and from simulations utilizing the Earth Radiation Budget Experiment (ERBE) scene model and various datasets for the cloud cover, as well as snow and ice cover. With these, we look for inter-annual and longer-term changes in the earth's total reflectance, or Bond albedo. We find that both our observations and simulations indicate that the albedo was significantly higher during 1994-1995 (activity minimum) than for the more recent period covering 1999-2001 (activity maximum). However, the sizes of the changes seem somewhat discrepant. Possible indirect solar influences on the earth's Bond albedo are discussed to emphasize that our earthshine data are already sufficiently precise to detect, if they occur, any meaningful changes in the earth's reflectance. Still greater precision will occur as we expand our single site observations to a global network.

• 한국식품영양과학회지
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• 제33권3호
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• pp.582-586
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• 2004

면역결핍 환자들에게 공급하기 위한 무균식 제품 기술개발의 일환으로 쌀밥에 0, 5, 10 kGy로 감마선 조사하여 3$0^{\circ}C$에서 저장하면서 색, 물성 및 저장성에 미치는 영향을 조사하였다. 감마선 조사선량과 저장기간이 증가할수록 yellowness는 유의적으로 증가하는 경향을 나타내었으며, 10 kGy 조사구의 부착성은 유의적으로 감소하여 부착성과 경도의 비가 감소하는 경향을 나타내었다. 총균수는 비조사구의 경우 저장 3일 후 7 log cycle까지 증가하였으나 5 kGy 조사구는 저장 4주 후 4 log cycle수준을 유지하였으며 10 kGy 조사구의 경우는 검출되지 않았다. 감마선 조사의 선량은 색도, 물성 및 미생물적인 측면을 고려하였을 때 5 kGy 내외가 적당할 것으로 생각되며 5 kGy로 조사하였을 경우 3$0^{\circ}C$ 저장시 1개월 이상의 저장기간을 연장시킬 수 있을 것으로 사료된다. 또한 장기 저장을 위한 고선량 적용을 위해 색도의 변화 및 물성 변화를 최소화할 수 있는 방안에 대한 연구가 계속되어야 할 것으로 생각된다.

• 소성∙가공
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• 제27권4호
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• pp.250-256
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• 2018

Oxygen-free copper (OFC) was prepared as a 90 mm cube and then processed with Multi-Axial Diagonal Forging - Initialization of Prior manufacturing History (MADF). The MADF process has been newly developed as a severe plastic deformation method. The MADF process consists of upset forging with a thickness reduction of 30% and diagonal forging with a diagonal angle of $135^{\circ}$. 1 cycle process consists of a 12 passes forging process. In order to analyze the characteristic changes according to the number of iterations, 1, 2, and 3 cycles of the MADF process were performed. The OFC specimens were MADF processed without surface cracks up to 3 cycles. The microstructure, hardness and tensile test of processed materials were analyzed to study the change of material properties according to the amount of MADF process. The results showed that the MADF process effectively refined the microstructure and increased the strength of OFC. In the case of specimens processed for more than 2 cycles, the grains of all measurement regions were refined to be less than $7{\mu}m$ of grain size. The 1 cycle MADF processed OFC showed the highest mechanical properties with the hardness of 132 HV and tensile strength of 395 MPa. Hardness and strength seemed to be saturated when processed over 2 cycles.

• Journal of Acupuncture Research
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• 제18권1호
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• pp.129-145
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• 2001

Objectives : To characterize the antitumorigenic potential of three representative bee venom components, Melittin, Apamin, and Phospholipase A2, their effects on cell proliferation and apotosis of the human melanoma cell line SK-MEL-2 were analyzed using molecular biological approaches. Methodes & Results : To determine the doses of the drugs that do not induce cytotoxic damage to this cell line, cell viability was examined by MTT assay. While SK-MEL-2 cells treated with 0.5 - 2.0㎍/㎖ of each drug showed no recognizable cytotoxic effect, marked reductions of cell viability were detected at concentrations over 5.0㎍/㎖. [3H]thymidine incorporation assay for cell proliferation demonstrated that DNA replication of SK-MEL-2 cells is inhibited by Apamin and Phospholipase A2 in a dose-dependent manner. Consistent with this result, the cells were accumulated at the G1 phase of the cell cycle after treatment with Apamin and Phospholipase A2, whereas no detectable change in cell proliferation was identified by Melittin treatment. In addition, tryphan blue exclusion and flow cytometric analyses showed that all of these drugs can trigger apoptotic cell death of SK-MEL-2, suggesting that Melittin, Apamin, and Phospholipase A2 have antitumorigenic potential through the suppression of cell growth and/or induction of apoptosis. Qantitative RT-PCR analysis revealed that Apamin and Phospholipase A2 inhibit expression of growth-promoting genes such as c-Jun, c-Fos, and Cyciin D1. Furthermore, Phospholipase A2 induced tumor suppressors p53 and p21/Wafl. In addition, all three drugs were found to activate expression of a representative apoptosis-inducing gene Bax while expression of apoptosis-suppressing Bcl-2 and Bcl-XL genes was not changed. Taken together, this study strongly suggests that Metittin, Apamin, and Phosphalipase A2 may have antitumorigenic activities, which are associated with its growth-inhibiting and/or apoptosis-inducing potentials.