• 제목/요약/키워드: Cycle change-over

검색결과 206건 처리시간 0.032초

Reinfection by Opisthorchis Viverrini after Treatment with Praziquantel

  • Saengsawang, Phubet;Promthet, Supannee;Bradshaw, Peter
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.857-862
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    • 2016
  • Background: The prevalence of infection by the liver fluke, Opisthorchis viverrini (O. viverrini), has remained high in Northeast Thailand where it is a major risk factor for the eventual development of cholangiocarcinoma (CCA). The infection is acquired by the consumption of dishes containing unsafely prepared freshwater fish, a dietary tradition which has proved resistant to change. Since many people are aware that dosing with praziquantel (PZQ) is a successful treatment for an episode of the infection, there is a risk that, to avoid the long term consequences, they will engage in a cycle of infection, dosing and reinfection. Objectives: There is a dearth of studies of reinfection by O. viverrini, and the aims of this study were to assess re-infection rates in a typical province of Northeastern Thailand where O. viverrini infection is likely and to investigate factors associated with reinfection. Materials and Methods: A total of infected 607 villagers were treated with PZQ, and those found to be no longer infected were followed up at six-monthly intervals over 12 months. Results: At the end of this period data on 457 subjects were available for analysis using descriptive statistics and logistic regression, and 50 were found to have become reinfected, giving a cumulative reinfection rate of 10.9%. The results of a multiple logistic regression analysis showed that the only factor found to be associated with reinfection was past use of PZQ. Conclusions: Recommendations are made for future larger scale and better designed reinfection studies in the light of limitations of the current study. Further efforts are needed to discourage people from eating fish dishes likely to contain viable metacariae.

낙동강 하구 해양환경 및 기상 요인이 김P(orphyra yezoensis) 생산량 변화에 미치는 영향 (Effects of Meteorological and Oceanographic Properties on Variability of Laver Production at Nakdong River Estuary, South Coast of Korea)

  • 권정노;심정희;이상용;조진대
    • 한국수산과학회지
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    • 제46권6호
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    • pp.868-877
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    • 2013
  • To understand the effects of marine environmental and meteorological parameters on laver Porphyra yezoensis production at Nakdong River Estuary, we analyzed marine environmental (water temperature, salinity, nutrients, etc.) and meteorological properties (air temperature, wind speed, precipitation, sunshine hours) with yearly and monthly variations in laver production over 10 years (2003-2013). Air and water temperature, wind speed, sunshine hours and precipitation were major factors affecting yearly variability in laver production at the Nakdong River Estuary. Lower air and water temperatures together with higher levels of nutrients and sunshine and stronger wind speeds resulted in higher laver harvests. Salinity and nitrogen did not show clear correlations with laver production, mainly due to the plentiful supply of nitrogen from river discharge and the low frequency of environmental measurements, which resulted in low statistical confidence. However, environmental factors affecting monthly laver production were related to the life cycle (culturing stage) of Porphyra yezoensis and were somewhat different from factors affecting annual laver production. In November, a young laver needs lower water temperatures for rapid growth, while a mature laver needs much stronger winds and more sunshine, as well as lower temperatures for massive production and effective photosynthesis, mostly in December and January. However, in spring (March), more stable environments with fewer fluctuations in air temperature are needed to sustain the production of newly deployed culture-nets ($2^{nd}$ time culture). These results indicate that rapid changes in weather and marine environments caused by global climate change will negatively affect laver production and, thus, to sustain the yield of and predict future variability in laver production at the Nakdong River estuary, environmental variation around laver culturing farms needs to be monitored with high resolution in space and time.

Synthesis and Characterization of Biodegradable Elastic Hydrogels Based on Poly(ethylene glycol) and Poly(${\varepsilon}-caprolactone$) Blocks

  • Im, Su-Jin;Choi, You-Mee;Subramanyam, Elango;Huh, Kang-Moo;Park, Ki-Nam
    • Macromolecular Research
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    • 제15권4호
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    • pp.363-369
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    • 2007
  • Novel biodegradable elastic hydrogels, based on hydrophilic and hydrophobic polymer blocks, were synthesized via the radical crosslinking reaction of diacrylates of poly(ethylene glycol) (PEG) and poly(${\varepsilon}-caprolactone$) (PCL). PEG and PCL diols were diacrylated with acryloyl chloride in the presence of triethylamine, with the reaction confirmed by FT-IR and $^1H-NMR$ measurements. The diacrylate polymers were used as building-blocks for the syntheses of a series of hydro gels, with different block compositions, by simply varying the feed ratios and molecular weights of the block components. The swelling ratio of the hydrogels was controlled by the balance between the hydrophilic and hydrophobic polymer blocks. Usually, the swelling ratio increases with increasing PEG content and decreasing block length within the network structure. The hydrogels exhibited negative thermo-sensitive swelling behavior due to the coexistence of hydrophilic and hydrophobic polymer components in their network structure, and such thermo-responsive swelling/deswelling behavior could be repeated using a temperature cycle, without any significant change in the swelling ratio. In vitro degradation tests showed that degradation occurred over a 3 to 8 month period. Due to their biodegradability, biocompatibility, elasticity and functionality, these hydrogels could be utilized in various biomedical applications, such as tissue engineering and drug delivery systems.

생애구술을 통해 본 주거의 의미와 사용 I : 주거의 의미를 중심으로 (Meaning and Use of Housing Through Life History I : Focused on the Meaning of Housing)

  • 홍형옥;양세화;전남일
    • 가정과삶의질연구
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    • 제27권1호
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    • pp.45-60
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    • 2009
  • This study was designed to examine the meaning of housing in modern Korea, and to draw the interrelationship of people and housing. In-depth interviews were conducted, and the qualitative research investigated various aspects of housing history among four individuals during the different phases of social and economic transitions. Each narratives showed the unique characteristics of life history, and the conceptual frameworks for interpretation were microsociological approach by Morris and Winter(1978) and pathway approach by Clapham(2005). One narrater named "K" had gone through various housing experiences since her birth in 1933 at a traditional Korean housing, and she moved to a traditional rural community. Another narrater called "S" was born in housing built during the Japanese colonization, gained wealth through the housing boom of the industrialization, and has lived in a suburban condominium. "G" spent her entire life in an urban area, had never owned a house, and lived in a house with poor quality. The other narrater named "L" had lived in a single-family home with a large yard since her childhood, and she has resided in multi-family housing by herself after having a lot of experiences of building houses. The results revealed that housing could play as a simple role as a shelter, be transformed over family life cycle, become prestige of extended family, social and family status, investment. Meaning of housing from the pathway approach were closely related to hometown, the relation to birth family at postmarriage, economic status, and housing experiences according to the social change. As a conclusion, the meaning of housing is vary, and housing conveys numerous implications including psychological, social and economic aspects.

산업체에서의 데이터와 신뢰성평가 (Data and reliability evaluation in industry)

  • 백재욱
    • 산업진흥연구
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    • 제2권1호
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    • pp.1-7
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    • 2017
  • 제조기업의 경우 여러 종류의 데이터가 수집된다. 이 중 많은 데이터는 약간만 변형하면 제품의 신뢰성 평가에 유용한 정보로 활용될 수 있다. 이 연구에서는 우선 제조기업에서 수집될 수 있는 데이터로 제품, 기술, 재무, 고객 등과 관련된 데이터는 어떤 것이 있는지 살펴본다. 다음으로 데이터가 발생할 수 있는 근원으로서 회사의 비즈니스 매니지먼트 시스템, 과학저널, 시험 및 마케팅조사 데이터 등에 대해 알아본다. 다음으로 제품의 신뢰성평가를 위해 제품수명주기에 걸쳐 어떤 종류의 데이터가 수집되는지 알아본다. 우선 제품의 개발단계에서는 구성요소별로 신뢰성시험을 실시하고, 서브시스템 및 시스템 차원에서도 신뢰성시험을 실시하여 신뢰성 관련 데이터를 수집한다. 한편, 제조단계에서는 제품의 기능시험 및 설계변경시험 등에 관한 데이터를 수집하고, 필드단계에서는 제품의 필드에서 어떤 문제가 일어나는지 파악하여 데이터의 형태로 수집한다. 마지막으로 데이터 수집 시 추후의 합리적인 분석을 위해 들어가야 할 내용이 무엇인지 살펴본다.

새만금 방조제 완공 이전 만경강 하구역 식물플랑크톤 군집의 주기적인 변동 (Cyclic Change of Phytoplankton Community in Mankyeong River Estuary prior to the Completion of the Saemankeum Seawall)

  • 김영길;박종우;장건강;이원호
    • Ocean and Polar Research
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    • 제31권1호
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    • pp.63-70
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    • 2009
  • Eutrophicated water fed through Mankyeong River and Dongjin River into the new Saemankeum Lakemight seriously affect the water quality and phytoplankton community in the lake. To obtain control reference data for the later studies on environmental changes due to the construction of the Saemankeum Sea Wall, we performed a monthly investigation on the physico-chemical properties of the water and phytoplankton community at 3 stations in the Mankyeong River Estuary over 14 months starting from September 1999. Water temperature ranged from $0.3{\sim}32.9^{\circ}C$ due to the typical seasonal variations in temperate on the coasts and salinity exhibited a wide annual range of $0.2{\sim}33.7$ psu along with regular and huge hourly variations according to tidal cycles. Inorganic nutrients were supplied from rivers to the monitoring station and the whole lake. The average concentration of total-N, $6.99\;mg{\cdot}l^{-1}$, was higher than the water quality for agricultural use with peak values occurring in winter. Species composition showed a seasonal succession pattern, where a high diversity was observedin summer and autumn and vice versa in winter. Hourly variations of water properties in the "Mankyeong bridge" Station were quite regular and well in accordance with the daily tidal cycles. The different degree of sea water intrusion during the flood tide at each of the 3 stations exhibited a different range and variation pattern of water temperature and salinity throughout a day. Hourly changes in species composition were in harmony with the daily tidal cycles, resulting in extremely variable spatio-temporal variation.

제주도 고산지역의 대기 라돈 배경농도 및 시계열 변동 (Background Level and Time Series Variation of Atmospheric Radon Concentrations at Gosan Site in Jeju Island)

  • 송정민;부준오;김원형;강창희;고희정
    • 한국대기환경학회지
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    • 제33권2호
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    • pp.174-183
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    • 2017
  • The background level and timely variation characteristics of atmospheric $^{222}Rn$ concentrations have been evaluated by the real time monitoring at Gosan site of Jeju Island, Korea, during 2008~2015. The average concentration of atmospheric radon was $2,480mBq\;m^{-3}$ for the study period. The cyclic seasonality of radon was characterized such as winter maximum and summer minimum, consistent with the reduction in terrestrial fetch going to summer. On monthly variations of radon, the mean concentration in October was the highest as $3,041mBq\;m^{-3}$, almost twice as that in July ($1,481mBq\;m^{-3}$). The diurnal radon concentrations increased throughout the nighttime approaching to the maximum ($2,819mBq\;m^{-3}$) at around 7 a.m., and then gradually decreased throughout the daytime by the minimum ($2,069mBq\;m^{-3}$) at around 3 p.m. The diurnal radon cycle in winter showed comparatively small amplitude due to little variability in atmospheric mixing depth, conversely, large amplitude was observed in summer due to relatively a big change in atmospheric mixing depth. The cluster back-trajectories of air masses showed that the high radon events occurred by the predominant continental fetch over through Asia continent, and the radon concentrations from China continent were about 1.9 times higher on the whole than those from the North Pacific Ocean. The concentrations of $PM_{10}$ also increased in proportion to the high radon concentrations, showing a good linear correlation between $PM_{10}$ and radon concentrations.

DEVELOPMENT OF LEAD SLOWING DOWN SPECTROMETER FOR ISOTOPIC FISSILE ASSAY

  • Lee, YongDeok;Park, Chang Je;Ahn, Sang Joon;Kim, Ho-Dong
    • Nuclear Engineering and Technology
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    • 제46권6호
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    • pp.837-846
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    • 2014
  • A lead slowing down spectrometer (LSDS) is under development for analysis of isotopic fissile material contents in pyro-processed material, or spent fuel. Many current commercial fissile assay technologies have a limitation in accurate and direct assay of fissile content. However, LSDS is very sensitive in distinguishing fissile fission signals from each isotope. A neutron spectrum analysis was conducted in the spectrometer and the energy resolution was investigated from 0.1eV to 100keV. The spectrum was well shaped in the slowing down energy. The resolution was enough to obtain each fissile from 0.2eV to 1keV. The detector existence in the lead will disturb the source neutron spectrum. It causes a change in resolution and peak amplitude. The intense source neutron production was designed for ~E12 n's/sec to overcome spent fuel background. The detection sensitivity of U238 and Th232 fission chamber was investigated. The first and second layer detectors increase detection efficiency. Thorium also has a threshold property to detect the fast fission neutrons from fissile fission. However, the detection of Th232 is about 76% of that of U238. A linear detection model was set up over the slowing down neutron energy to obtain each fissile material content. The isotopic fissile assay using LSDS is applicable for the optimum design of spent fuel storage to maximize burnup credit and quality assurance of the recycled nuclear material for safety and economics. LSDS technology will contribute to the transparency and credibility of pyro-process using spent fuel, as internationally demanded.

환측 신발 높이기가 편마비 환자의 보행 특성에 미치는 영향 (The Effect of Shoe Lift of the Paretic Limb on Gait Patterns in Hemiplegics)

  • 윤정규;박정미;김종만
    • 한국전문물리치료학회지
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    • 제9권2호
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    • pp.83-96
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    • 2002
  • The purpose of this study was to determine the effect of lift to the shoe of the affected limb on gait patterns in subjects with hemiplegia. The subjects of this study were 18 post-stroke hemiplegics. For the study, insole of the paretic side was lifted 10mm higher, and duration of static weight bearing, dynamic weight bearing and stance phase were measured from one cycle of the gait, before and after the lift application. For the measurement of carry-over effect of lift, we got data of those three items prior to and 3 weeks after lift application and 3 days after removal of the lift. Static weight bearing was significantly increased both just after and continuous application of lift for 3 weeks than before. Dynamic weight bearing was significantly decreased in heel contact and footflat phases only when just after application of the lift, without any change after 3 weeks application. In heel-off phase, dynamic weight bearing did not show any significant difference between before and just after application of lift whereas significantly decreased after 3 weeks application. Duration of stance phase was not changed among anytime of application. According to this study, lift applied to the shoe of the peretic limb was effective in inducing static weight bearing in the paretic limb, but did not significantly effect dynamic weight bearing on gait patterns. This study suggests that symmetry, induced by shoe lift applied to the paretic limb, could help correct abnormal posture that would be caused in standing and prevent development of abnormal muscle tone in subjects with hemiplegia caused by unilateral stroke.

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Spin-coating법에 의한 $TiO_2$의 광촉매 효율 (Photocatalytic Efficiency of $TiO_2$Thin Films by Spin-coating)

  • 김범준;변동진;이중기;박달근
    • 한국재료학회지
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    • 제10권4호
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    • pp.264-269
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    • 2000
  • $TiO_2$sol(30wt%, anatase)을 이용하여 스핀코팅으로 유리기판에 $TiO_2$박막을 제조하였다. 박막의 두께는 코팅주기의 횟수가 조절하였다. 한 코팅주기는 스핀코팅, 건조, 열처리를 포함한다. 박막의 반응성은 막 위에서의 자외선강도가 0.44와 2.mW/$\textrm{cm}^2$인 조건에서 벤젠기체의 광분해 속도를 통해 조사하였다. 박막의 두께가 증가할수록 표면적으로 증가로 인해 반응성은 증가하였으며, 0.44mW/$\textrm{cm}^2$일 때 4$\mu\textrm{m}$정도 이상의 두께에서 반응성은 더 이상 증가되지 않았다. porous한 $TiO_2$박막은 비교적 넓은 유효표면적을 가지고 있으며, 그것은 비교적 높은 자외선 강도하에서 박막두께에 따라 반응속도를 증가시키는 결과를 낳았다.

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