• Title/Summary/Keyword: Cyanohydrin trimethylsilyl

Search Result 2, Processing Time 0.016 seconds

Cyanosilylation of Carbonyl Compounds Catalyzed by Potassium L-Aspartate

  • George, Soney C.;Kim, Sung-Soo;Kim, Ho-Sub
    • Bulletin of the Korean Chemical Society
    • /
    • v.28 no.12
    • /
    • pp.2431-2434
    • /
    • 2007
  • Potassium L-aspartate has been used as a catalyst for the cyanosilylation of carbonyl compounds producing corresponding cyanohydrin trimethylsilyl ethers in excellent yield of up to 98%. Although the catalyst is chiral, the enantioselectivities observed are generally poor except for one case, α-naphthaldehyde, 89% ee.