The purpose of this study was to evaluate whether wild ginseng (WG) administration could attenuate anxiety- and depression-like behaviors and expression of corticotrophin-releasing factor (CRF) and neuropeptide Y (NPY) following withdrawal from repeated morphine administration in rats. Male rats were administered daily doses of WG (50, 100, or 200 mg/kg, i.p.) for 5 days, 30 min before morphine injection (40 mg/kg, s.c). The anxiety- and depression-like behavioral responses were measured 72 h after the last morphine injection using an elevated plus maze (EPM) and forced swimming test (FST), respectively. Changes in hypothalamic CRF and NPY expressions were also examined by analyzing their immunoreactivities in the hypothalamus. Daily administration of WG significantly reduced anxiety- and depression-like behavior, and elicited the suppression of CRF expression and the stimulation of NPY expression in the hypothalamus. Our results demonstrated that WG extract might be effective at inhibiting the anxiety and depression responses due to morphine withdrawal by possibly modulating the hypothalamus CRF and NPY systems. Furthermore, these findings imply that WG extract can be used for developing new medication to cure or alleviate morphine withdrawal symptoms and to prevent relapses of morphine use.
Journal of the Korean Academy of Child and Adolescent Psychiatry
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v.4
no.1
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pp.27-38
/
1993
Pervasive developmental disorder is one of the most severe clinical disorder in child psychiatry and is associated with deviancies in multiple areas of development. Medication does not cure pervasive developmental disorder and its effectiveness is generally nonspecific. But psychopharmacological treatment can be important for some children with pervasive developmental disorder and can make many young autistics more amenable to behavior modification and education. Haloperidol, the most widely studied antipsychotics, was statistically and clinically superior to placebo, and furthermore, was known to facilitate the positive functioning such as, discrimination learning and imitative communication, without side effects. However, administration of haloperidol is associated with drug related dyskinesia, and it warrants the introduction and use of the other novel drugs. Several biochemical studies suggest that subgroups of children with pervasive developmental disorder show hyperserotonemia and increased endogenous opioid level as compared with controls. Psychopharmacological trials were conducted according to these findings(ex : fenfluramine, naltrexone), with mixed results till now. These and another drugs that have been used in children with pervasive developmental disorder and their effectiveness are reviewed.
The purpose of this study is to make clear the durability of the polymer films formed in the autoclaved polymer-modified mortars and concretes. The polymer films prepared with polymer dispersions such as a styrene-butadiene rubber (SBR) latex, a poly (ethylene-vinyl acetate)(EVA) emulsion and a polyacrylic ester (PAE) emulsion for polymeric admixtures are exposed to autoclaving at 18$0^{\circ}C$ in temperature and 1.01 MPa in vapor pressure, and subjected to tensile test and infrared spectroscopy. The durability of the polymer films is evaluated from the application of autoclaving to the polymer films under saturated Ca(OH)$_2$ solution immersion causes no degradation for SBR films and a significant degradation due to the saponification of the polymers for EVA and PAE films. Accordingly, in the application of autoclaving to polymer-modified mortars and concretes, it is suggested that SBR-modified mortars and concretes are hardly degraded but EVA- and PAE-modified mortars and concretes are markedly degraded by the saponification of the polymers.
Journal of Dental Rehabilitation and Applied Science
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v.30
no.1
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pp.36-44
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2014
Bruxism is a much-discussed clinical issue in dentistry. Although bruxism is not a life-threatening disorder, it can influence the quality of human life, especially through dental problems, such as, frequent fractures of dental restorations and pain in the orofacial region. This research has a goal to investigate the diagnostic methods of bruxism, to provide an appropriate information about various treatment in clinical situation, and to evaluate the effect and the usefulness of those methods. There is no certain remedy for bruxism that is a technically efficient and definitely reliable diagnosis and treatment. So, the primary purpose is to prevent the oral and maxilofacial tissue injuries from bruxism and to relieve the pain and symptom. Therefore, Combining various reversible treatments together, such as behavior modification, Oral appliances therapy and physiotherapy, is recommended. For a bruxism treatment in dental field, more researches about the factors influencing on diagnosis and cure are necessary.
Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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2018.10a
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pp.58-61
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2018
In Korea, current medical technology is the highest level in the world. As a result, many doctors have specialized knowledge of various disorders or diseases, and are proceeding in a better way. With such high medical technology, it is possible to increase the probability of success of surgery to provide high reliability to patients. Rehabilitation is also a form of medical treatment that reduces the side effects that occur after surgery that is done for quick cure. However, the situation in this section is slightly different. There are moves to develop rehabilitation devices and operations, but most of them are now dependent on foreign technology. Rehabilitation therapy, which we commonly know, is dominated by behavior. However, it is also a kind of rehabilitation to find out how much the patient's symptoms are improved or recovered. In this paper, we have studied the development of a program by using the Deeplearning method in order to detect the problem of the food swallowing operation by the severity.
Cotton fabrics were treated with gelatin to enhance dyeability and color strength when using Caesalpinia sappan dye. Gelatin was used as the protein and a pad-dry- cure method was used for the treatment process (2, 4, 6, 8, 10, 12, 14g/l concentration). Pretreated fabrics were mordanted with 10% alum. Fabrics were then dyed with freeze-dried sappan wood water extract powder form. Dyed samples were assessed in regards to dyeing behavior and color fastness. Comparing untreated and gelatin treated samples from the SEM images indicated that the Gelatin treatment (10g/l) resulted in an enhanced surface roughness that was relative to that of untreated cotton. Padding cotton with gelatin at 6g/l concentration afforded dyed fabrics with a 2 times increase in the K/S value over that of untreated fabrics. All dyed samples were red color with a significant enhancement in the sample color strength (K/S) being observed for pretreated samples. pH values favor dye absorption with pH 7 yielding the highest color strength. Dyeing at an elevated temperature resulted in a lower color strength and reddish-dull color. Longer dyeing times created greater color strengths for untreated and gelatin treated cotton. Increased dye concentrations resulted in higher K/S values for both gelatin treated and untreated cotton. As for color fastness, gelatin treated and untreated cotton fabrics dyed with sappan wood extract showed a relatively low rating in washing fastness (color change 1 rating), light fastness (1 rating), and rubbing fastness (wet:1-2, dry:3-4 rating).
Interstitial lung diseases (ILDs) are a diverse collection of lung disorders sharing similar features, such as inflammation and fibrosis. The diagnosis and management of ILD require a multidisciplinary approach using clinical, radiological, and pathological evaluation. Progressive pulmonary fibrosis (PPF) is a distinct form of progressive and fibrotic disease, occurring in ILD cases other than in idiopathic pulmonary fibrosis (IPF). It is defined based on clinical symptoms, lung function, and chest imaging, regardless of the underlying condition. The progression to PPF must be monitored through a combination of pulmonary function tests (forced vital capacity [FVC] and diffusing capacity of the lung for carbon monoxide), an assessment of symptoms, and computed tomography scans, with regular follow-up. Although the precise mechanisms of PPF remain unclear, there is evidence of shared pathogenetic mechanisms with IPF, contributing to similar disease behavior and worse prognosis compared to non-PPF ILD. Pharmacological treatment of PPF includes immunomodulatory agents to reduce inflammation and the use of antifibrotics to target progressive fibrosis. Nintedanib, a known antifibrotic agent, was found to be effective in slowing IPF progression and reducing the annual rate of decline in FVC among patients with PPF compared to placebos. Nonpharmacological treatment, including pulmonary rehabilitation, supplemental oxygen therapy, and vaccination, also play important roles in the management of PPF, leading to comprehensive care for patients with ILD. Although there is currently no cure for PPF, there are treatments that can help slow the progression of the disease and improve quality of life.
Although the officially confirmed incidence of the acquired immune deficiency syndrome(AIDS) has remained low thus far in Korea, the progression of the pandemic has been rapid, concerned about an eventual increase in transmission. Until a vaccine or cure is found, public information and education remain an important weapon against AIDS. For the year 2000, the current WHO projection is that there will be a cumulative total of 40 million HIV infections in man, woman and children, of which more than 90% will be in the developing countries. The incerased mortality among adults and children has raised concerns that AIDS may become so devastaing as to reverse positive population growth rates and wipe out entire population. In order to plan for the rising incidence of patient with AIDS, an assessment of AIDS-related cognition and behavior, attitude of the recognized high-risk groups is necessary. Considering that undergraduates have sexuality active and more oriented toward sexual concerns than other ages. Adolescents today are more sexually involved than in the past: The media, including films, music, and television, reinforce sexual concerns by preseating images of highly sexual adolescents. Incidence of both petting and sexual intercourse in higher and occurs at earlier ages, they are important reservoir of AIDS infection. Hence, it has become important to emymerats and describe the knowledge, attitude and behavior of them, I want.. This information will eventually guide the direction of change in public policies and education programs to meet the challenges of AIDS. The objective of this study were to identity Knowledge, Attitude, Experience of Sex and AIDS in Korea. The data were collected by survey at Korean Federation for AIDS Affairs, INC. and J university, K junior college. After October in 1993, surveyed with 507 student during their's college days in Seoul. The questionnaire was designed to provide information on sex and AIDS-related knowledge and attitudes and experience. AIDS-related knowledge was measured by using 26 questions on mode of transmission and AIDS-related attitudes were measured by 7 questions, AIDS-related experience was measured by 5 questions. There were the main dependent variables in our study, In conclusion, students during their university day need to develop AIDS-preventive education programs. Clearly, the many AIDS-prevention educational effort need to be guided by well trained health agents. Financial supports from all sectors (i.e., public and private) of our society are required to achieve that end. Further researches on AIDS-related Knowledge and Attitude and behaviors of undergraduates are needed for the development of comprehensive AIDS prevention programs.
This research carried out a survey for 569 students in a junior college of jeollanamdo to provide a needful basic data in developing suitable health promotion program and creating a direction of the oral hygiene education process to intial adult population after holding the oral cavity health action and a affecting factors to it. A collected data obtained the following conclusion. According to school grade, a difference of action factor is Chi-square and Pearson's correlation coeficient in actionfactor and acknowledgement-perception factor and a step-by-step recurrence analysis processed a related factor of the oral health action. 1. A related action factor of the oral health appeared meaningful difference of the oral cavity medical examination, the oral cavity clean device use or not, dental surgery prevention cure or not among the third grade who had the most experience of the oral hygiene education within one year recently. 2. A significant of the oral cavity health acknowledged and perceived and a concern of the oral cavity health, acknowledged the oral cavity health state distribution are the highest in the third grade. 3. According to monthly income, a large income is higher than a small income about self-effects in a relation between the oral cavity health action and acknowledgement-perception factor. the average of a large income is 30.59(${\pm}5.79$). The obstacle of the oral cavity health action is 12.51(${\pm}3.19$). a large income is highest. according to school career, under middle school layer obtained the highest average 16.33(${\pm}3.53$). according to a school year, acknowledge-perception factor of the oral cavity health control of the third grade is the highest(38.81(${\pm}6.25$). 4. In mutual relation between acknowledge-perception factor and the oral cavity health action, a variable constants of meaningful mutual relation are the oral cavity health perception, self-effects, the oral cavity health action obstacle, the oral cavity health action benefit, the oral health action control, aggressive. and they are self-effects, the oral cavity health action in the oral cavity health perception. A significant of the oral cavity health and the oral cavity health action obstacle are the oral cavity health action benefit and the oral cavity health action control. 5. The affecting factors to the oral health action are self-effects, action factor, acknowledged the oral health control.
This study aims to analyze effects of mothers' socioeconomic features, and knowledge and behavior of oral health on experience and purpose of using dentistry. By survey to 103 mothers of 5-6 year old children, who use day care centers in seoul, the results are obtained as follows: 1. As for the rate of experiencing dental care classified by its purpose, 56.7% for dental treatment, 23.3% for regular check-up and 20.0% for precaution 2. There was no significant difference of correlativity between mothers' socioeconomic features and knowledge of oral health and experience of using dental care, while the lower rate of using dental floss, the higher rate of experiencing dental care(p < 0.01). 3. In respect of correlativity between mother's socioeconomic features and purpose of using dental care, the purpose of regular checkup was high in a group of mothers between 33 and 35 years old(71.4%) by ages and in a group of mothers who graduated from college(57.1%) by academic background(p < 0.05). 4. In correlativity between mothers' behavior of oral health and purpose of using dental care, the result showed that the higher the rate of using dental floss was, the higher the rate of experiencing dental care for a regular check-up was(p < 0.001) and the higher the rate of using fluoride dentifrices was, the higher the rate of using dental care for cure was(p < 0.05). 5. Multiple regression based on dependent variable of experience in using dental care showed that average monthly income(less than 2,500,000 won) was significant explanatory factor with 65% of explanatory variance. On the other hand, multiple regression based on dependent variable of purpose of using dental care showed that vocation(professional job) and age(between 33 and 35 years old) was significant explanatory factor with 70% of explanatory variance for a regular check-up, age(between 33 and 35 years old) and average monthly income (less than 2,500,000 won) was significant factor with 78% of explanatory variance for precaution and age(less than 32 years old) was significant explanatory factor with 33% of explanatory variance for treatment.
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