• Journal of Life Science
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• v.11 no.6
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• pp.543-553
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• 2001

Lead poisoning is currently one of the major public health problems in industrialized countries. Several chelating agents have been developed and used to treat the lead poisoning. It was recently proposed that garlic, having a large quantity of S-S compounds, may react readily with lead, producing various sulfur componds, and thus provide curative and protective effects on the lead toxicity. The present study was undertaken to evaluate this possibility in experimental animals. The garlic treatment on rats pre-exposed to lead significantly enhanced urinary excretion of lead at a garlic dose of 500 mg/kg and decreased the bloon level of lead at both 250 and 500 mg/kg doses. The administration of grilic 500mg/kg along with lead significantly alleviated the renal histological alterations induced by lead. These results suggest that garilic has a curative as well as a protective effect against lead poisoning , thus it may act as a chelator of lead.

• Journal of the Korean Institute of Landscape Architecture
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• v.42 no.4
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• pp.37-47
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• 2014

This study aims to examine the usage of and satisfaction with neighborhood parks and university campuses and compare through the RPRS analysis of them to figure out how university campuses, as substitutive green spaces, play the role of curative environment for neighboring people. This study relied on two methods: a descriptive method of researching publications and related scholastic writings and an empirical study of researching how the park and campus has been utilized and researching whether the residents are satisfied with the currently existing space and the environment or not, and finally researching how the university campus open space as a curative environment impacts the satisfaction and utilization through reliability analysis. As a result, contribution of healing environment has a relatively high average contribution of 4 or more points, respectively. These results suggest that urban people think that a relationship between man and nature is very important in the overabundance of stress in modern society. It shows that neighborhoods are higher than university campuses in the explanatory of the Attention Restoration Theory, but the campus is higher than the neighborhood park in similarity of configuration. The result of RPRS analysis shows that the therapeutic qualities of the landscape may be very useful to evaluate a college campus open space in "the Revised Perceived Restoration Scale." The results showed that, in future studies, it will be a great help by widespread use of pre-evaluation of the characteristics of restorative environments in the planning, design and other works. To study the impact of the curative features on evaluating future research locations, the location should provide a variety of purposes and motives. At the same time, it should provide specific design ideas to design-related designers by using perceived restoration scale.

• Journal of Preventive Medicine and Public Health
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• v.15 no.1
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• pp.131-137
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• 1982

For the purpose of the curative effects of oral D-penicillamine in lead poisoning, D-penicillamine was orally administered to 7 lead poisoned workers which were employed in glaze product industry dealing with the lead oxide ($Pb_3O_4$). The doses of D-penicillamine was 1,200mg per day which was administered by oral 7days schedules, taking for 5 days and stopping for the following 2days, repeatedly during 3 months period. (All the poisoned workers started working again in that industry after 1 month treatment, and were treated by oral D-penicillamine for 2 months still being exposed to contaminated environment.) In order to evaluate the curative effects of D-penicillamine, 10gm of whole blood and 24 hours urine were collected every 14 days during the curative period for laboratory analysis(hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, urine coproporphyrin, and urine lead levels) with the observation of the clinical symptoms. The results were as follows; 1. Oral D-penicillamine effected good curative results as that hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, and urine coproporphyrin levels were decreased below the critical level within 1 month treatment. 2. After re-exposure, oral D-penicillamine effected to some extent as that urine lead level was decreased below the critical level after 3 months treatment with disappearence of the clinical symptoms after 2 months treatment. However, the curative effects of oral D-penicillamine in the lead exposure state is questionable since increasement of blood lead level and remarkable decreasement of urine lead level after 3 months treatment can be observed.

• Research in Plant Disease
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• v.23 no.2
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• pp.159-167
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• 2017

This study was conducted to evaluate the control efficacy of the organic farming materials on cucumber scab caused by Cladosporium cucumerinum PT1 (KACC 48094). The antifungal activities in vitro as well as the suppressive effect of 43 organic farming materials on the spore germination and germ tube growth by inoculating spore suspension on cucumber seedlings in vivo were investigated. Thirteen organic farming materials inhibited the mycelial growth of C. cucumerinum and nine of these were microbial agents. In the screening using cucumber seedlings, six organic farming materials were very effective with control efficacy value of 90%. Among them, Bacillus amyloliquefaciens M27 provided suppressive effect on both mycelial growth and spore germination against cucumber scab. Finally, nine organic farming materials were selected to test the protective and curative effects, and all chosen organic farming materials significantly suppressed disease incidence when applied in the preventive action, in comparison with the curative action. Especially, Bordeaux mixture I and III gave excellent protective control efficacy with control values of 96.7% and 73.3%, respectively, whereas its curative control effect was significant low. Among these, only Thymus quinquecostatus+Sophora extract showed curative activity, although the control value was as low as 50%. This study suggests that cucumber scab can be controlled by some organic farming materials in the farmhouses under comparatively cold and wet condition and protective treatment is more important and efficient.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.203-208
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• 2019

Medical color graphic research will serve as the basis for globally expanding and disseminating the design quality of the company's products through the era of production of medical robots. This study was based on technologies and contents suitable for the era of medical robot bed expansion, universal medical color application, ergonomic color, etc. In addition, the medical bed robot's color research direction was presented from the perspective of universal design. Accordingly, a universal color design was proposed, taking the functions of a medical robot under development by a domestic company as an example. The characteristics of this robot bed can be divided into three types of functions: first, treatment characteristics for prevention of pressure ulcers with curative, second, automatic seat exchange with cleanliness for medical environment, and third, Convenient, which can implement patient transport. The main idea is to present a combination of functional colors appropriate for this. The resulting color analysis and universal color design techniques could be a useful methodology for illustrating the appearance and function of a modern medical robot bed.

• Journal of Bio-Environment Control
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• v.22 no.4
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• pp.413-420
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• 2013

The purpose of this study was to evaluate the control efficacy of major environment-friendly control agents against powdery mildew, as affected by the application condition such as disease-developing stage and microclimate, as compared with the efficacy of pesticides in plug seedling of three Cucurbitaceae vegetables, including cucumber, melon, and oriental melon. Single or combined application of major six environment-friendly control agents was used in the experiment: two biofungicide (Ampelomyces quisqualis 94013 and Bacillus subtilis Y1336), two plant extracts (neem oil and extracts of Rheum undulatum), and two mineral materials (wettable sulfur powder and lime bordeaux mixture). These control agents were treated to the plug seedlings for preventing powdery mildew and curative applications for managing powdery mildew. In all treatments, the disease incidence declined as daily average temperatures increased to $30^{\circ}C$ for consecutive 6~8 days with maximum temperature over $40^{\circ}C$. In preventative application, the control efficacy against powdery mildew was the highest in the treatment of wettable sulfur powder, and lowest in the B. subtilis Y1336, with values of 20~40%. In cucumber seedlings, the preventive single application of neem oil or wettable sulfur powder was more effective than curative application of fungicides, while the control efficacy of these agents was similar to those of fungicides in melon seedlings. The single application of R. undulatum extracts was also effective in preventing the disease for both cucumber and melon seedlings, showing a higher control efficacy than those of biofungicides during seedling stage. The treatment of water spray was not effective and showed a higher disease incidence than the untreated control plot in the oriental melon and melon seedlings. The curative application with environment friendly control agents, after powdery mildew was first detected, could not successfully controlled the disease at the middle stage (5~10% of disease incidence) of disease development. The curative combined application of [R. undulatum extracts (1st application) + wettable sulfur powder (2nd) + neem oil (3rd)] showed the highest control efficacy among the other treatments, with control value over 80% at the early stage (less than 1% of disease incidence) of disease development.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2138-2140
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• 2016

The goal of this study was to identify a source of natural plant compounds with inhibitory activity against pepper mild mottle virus (PMMoV). We showed, using a half-leaf assay, that murrayafoline-A (1) and isomahanine (2) isolated from the aerial parts of Glycosmis stenocarpa have inhibitory activity against PMMoV through curative, inactivation, and protection effects. Using a leaf-disk assay, we confirmed that 2 inhibited virus replication in Nicotiana benthamiana. Using electron microscopy, we found that a mixture of the virus with 2 resulted in damage to the rod-shaped virus.

• Korean Institute of Interior Design Journal
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• v.20 no.4
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• pp.21-28
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• 2011

As people have paid much attention to their health along with increased interest in high quality of living, they have managed their health in organized manners. Space is a physical field which directly and indirectly interacts with human life, there is a little research on its therapeutic aspect and it is only negatively applied for development of products and alternative medicine. This study aims to identify research trends and flows targeting previous research on therapeutic approaches in domestic space design and present basic materials on space design approaches in a therapeutic view, which will be helpful in ultimate development of space design in theories and practices. As a result, it was discovered that there were only a few papers which were searched with direct key words on curative environment, which indicates that specific studies as therapeutic approaches are insufficient. When the studies were analysed according to annual publications, research on residential welfare and medical space was active, and research on design methodology, design techniques, and design plans was active, but research on psychology, behaviors, laws and institutions was relatively insufficient, which indicates studies on physical and psychological aspects of space design are necessary. In conclusion, it is suggested that further studies on therapeutic environment for direct and specific persons should be defined and classified although there have been relevant studies in various fields.

• The Korean Journal of Pesticide Science
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• v.18 no.2
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• pp.115-121
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• 2014

This study was performed to investigate the effect of conidial density, wetness period and temperature on conidial germination, appressoria formation and disease incidence. While there was not significantly correlated between conidial density and temperature, and conidial germination and appressoria formation, there was a significant correlation between those factors and disease incidence. The longer wetness period was, the higher the ratio of conidial germination, appressoria formation and the disease incidence was. The optimum conidial density, temperature and wetness period was $1{\times}10^6$ conidia $mL^{-1}$, $30^{\circ}C$ and 5 days, respectively. In case the wetness period was more than 5 days, the typical symptom was not found on pepper fruits because of the overgrowth of mycelia. Using this fruit assay method, which the pepper anthracnose pathogens were inoculated by spraying spore suspension on non-wounded or wounded pepper fruits, control effect of three fungicides were evaluated against pepper anthracnose by the protective and/or the curative application. Propineb showed high protective control activity, while it showed curative control activity on unwounded fruits, but did not showed curative control activity on wounded fruits. Tebuconazole, one of curative fungicide, showed higher control activity in non-wound inoculation than wound inoculation. Trifloxystrobin, one of strobilurin group, showed high both protective and control activity against anthracnose. In conclusion, we supposed that the newly developed in vitro pepper fruit assay can be used to evaluate antifungal activity of control agents against pepper anthracnose.

• Journal of Gastric Cancer
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• v.4 no.1
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• pp.27-31
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• 2004

Purpose: This study was designed to explore quality of life (QOL) in patients with stomach cancer by using the World Health Organization Quality of Life (WHOQOL) Instrument- Korean version. Materials and Methods: Thirty-one (31) patients with stomach cancer after curative resection were recruited with informed consent. Age- and gender-matched hospital staff served as controls. The 100-item WHOQOL Instrument, including physical domain, psychological domain, social domain, independence domain, environment domain, and spiritual domain, was employed for the all subjects. Results: In patients with stomach cancer after operation, only two domains, physical and independence, were associated with worse quality of life. In those domains, patients with advanced stage, with total gastrectomy, with adjuvant chemotherapy, and early or late postoperative period ($\leqq$2 years or >5 years after operation), could be perceived of having a worse quality of life. Conclusion: Not only scientific objective success but also individual subjective perception of condition could be important for managing patients with stomach carcinomas after curative resection. In this context, the WHOQOL reflecting multi-dimensional state of well being could be a useful tool across a variety of cultural and value systems in the world.