• Title/Summary/Keyword: Cumulative data

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Effects of Different Methods for Determining the Number of Transferable Embryos on Genetic Gain and Inbreeding Coefficient in a Japanese Holstein MOET Breeding Population

  • Terawaki, Y.;Asada, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제14권5호
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    • pp.597-602
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    • 2001
  • This study was conducted to examine the relationships between the methods used to determine the number of transferable embryos collected per flush and the estimated cumulative genetic improvements in the Japanese Holstein MOET breeding population. Cumulative genetic improvements were predicted by Monte Carlo simulation using three different determination methods (MODEL 1, MODEL 2, and MODEL 3), for calculating the number of embryos collected per flush. Moreover EBVs were estimated including or ignoring coefficients of inbreeding in MME. Inbreeding coefficients were also predicted. The number of transferable embryos was determined using normal, gamma, and Poisson distributions in MODEL 1, gamma and Poisson distributions in MODEL 2, and only the Poisson distribution in MODEL 3. The fitness of MODEL 2 in relation to field data from Hokkaido Japan was the best, and the results for MODEL3 indicated that this model is unsuitable for determining the number of transferable embryos. The largest cumulative genetic improvement (3.11) in the 10th generation was predicted by MODEL 3 and the smallest (2.83) by MODEL 2. Mean coefficients of correlation between the true and estimated breeding values were 0.738, 0.729, and 0.773 in MODELS 1, 2, and 3, respectively. It is suggested that the smallest genetic improvement in MODEL 2 resulted from the smallest correlation coefficient between the true and estimated breeding values. The differences in milk, fat, and protein yields between MODELS 2 and 3 were 182.0, 7.0, and 5.6 kg, respectively, in real units when each trait was independently selected. The inbreeding coefficient was the highest (0.374) in MODEL 2 and the lowest (0.357) in MODEL 3. The effects of different methods for determining the number of transferable embryos per flush on genetic improvements and inbreeding coefficients of the simulated populations were remarkable. The effects of including coefficients of inbreeding in MME, however, were unclear.

Percentage of motile spermatozoa at 22 hours after swim-up procedure: An indicator for intracytoplasmic sperm injection?

  • Inoue, Taketo;Yonezawa, Yukiko;Sugimoto, Hironobu;Uemura, Mikiko;Ono, Yuri;Kishi, Junji;Emi, Nobuyuki;Ono, Yoshiyuki
    • Clinical and Experimental Reproductive Medicine
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    • 제43권3호
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    • pp.157-163
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    • 2016
  • Objective: The decision to use in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), or split insemination (IVF-ICSI) in the first cycle is based on the number of motile sperm. Hence, total fertilization failure (TFF) often occurs during IVF cycles, despite normozoospermia. To investigate whether the cumulative motile swim-up spermatozoa percentage at 22 hours post-insemination (MSPPI) is an indicator for ICSI, we analyzed TFF, fertilization, blastocyst development, chemical pregnancy, clinical pregnancy, and live birth rates. Methods: This prospective study was performed using data obtained from 260 IVF cycles. At 22 hours after insemination, the remaining swim-up spermatozoa were observed and divided into six groups according to MSPPI (<10%, 10% to <30%, 30% to <50%, 50% to <70%, 70% to <90%, and 90% to 100%). Results: Regardless of the ejaculated motile sperm concentration ($0.6-280{\times}10^6/mL$ motile spermatozoa), the incidence of TFF significantly increased when MSPPI was <10%, and the fertilization rate significantly decreased when MSPPI was <30%. We found that cumulative MSPPI correlated with the cumulative fertilization rate (Spearman correlation, 0.508, p<0.001). Regarding embryo development, we observed no significant differences in the rates of blastocyst development, chemical pregnancy, clinical pregnancy, or live birth among all groups. Conclusion: Our findings suggest that MSPPI is a viable indicator for split IVF-ICSI and ICSI. Taken together, by employing the MSPPI test in advance before IVF, ICSI, or split IVF-ICSI cycles, unnecessary split IVF-ICSI and ICSI may be avoided.

Cumulative survival rate and associated risk factors of Implantium implants: A 10-year retrospective clinical study

  • Park, Jin-Hong;Kim, Young-Soo;Ryu, Jae-Jun;Shin, Sang-Wan;Lee, Jeong-Yol
    • The Journal of Advanced Prosthodontics
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    • 제9권3호
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    • pp.195-199
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    • 2017
  • PURPOSE. The objective of this study was to determine the cumulative survival rate (CSR) and associated risk factors of Implantium implants by retrospective clinical study. MATERIALS AND METHODS. Patients who received Implantium implants (Dentium Co., Seoul, Korea) at Korea University Guro Hospital from 2004 to 2011 were included. The period between the first surgery and the last hospital visit until December 2015 was set as the observation period for this study. Clinical and radiographic data were collected from patient records, including all complications observed during the follow-up period. Kaplan-Meier analysis was performed to examine CSR. Multiple Cox proportional hazard model was employed to assess the associations between potential risk factors and CSR. RESULTS. A total of 370 implants were placed in 121 patients (mean age, 56.1 years; range, 19 to 75 years). Of the 370 implants, 13 failed, including 7 implants that were lost before loading. The 10-year cumulative survival rate of implants was 94.8%. The multiple Cox proportional hazard model revealed that significant risk factor of implant failure were smoking and maxillary implant (P<.05). CONCLUSION. The 10-year CSR of Implantium implants was 94.8%. Risk factors of implant failure were smoking and maxillary implant.

Development of an Integrated Calorimeter Using Temperature Control Signals of a Bioreactor and On-line Measurement of Metabolic Heat of a Microbial Cultivation (발효조의 온도제어 신호를 이용한 직접열량계의 개발 및 대사열량의 온라인 측정)

  • Hong, Geon-Pyo;Heo, Won
    • KSBB Journal
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    • 제14권5호
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    • pp.543-549
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    • 1999
  • For development of an integrated calorimetric bio-reactor to measure the metabolic heat dissipated during cell growth, a 5 liter jar fermenter was modified to measure the pulse length of automatic temperature control signals to set heater on and off, and the to send them to computer to calculate the cumulative heat supplied. Cumulative heats for the calorimetric reactor in the absence of cell growth, were measured with varying conditions. The heat loss by the aeration was 30.9 kJ/vvm and the loss to ambient air was 10.5 kJ/L/hr/$^{\circ}C$. Cumulative heat was measued within $\pm$0.2% when testing with a small electri heater submerged in the reactor. Metabolic heat was measured to be 0.76 and 0.76 and 11.4kJ per g consumption of glucose during cultivation of S. cerevisiae and E. coli, respectively.

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Unconscious Response Characteristics of Pupils in the Observation toward to Spatial Image (공간이미지를 향한 주시에 나타난 동공의 무의식적 반응 특성)

  • Kim, Jong-Ha
    • Korean Institute of Interior Design Journal
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    • 제27권3호
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    • pp.136-144
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    • 2018
  • The purpose of this study is to examined the unconscious response of the pupil in the observation toward the image in the eye-tracking experiments that target on a large complex cultural space. Twenty-five men participated in this experiment and the observation data were analyzed in seconds per minute on watching time. It could examine the unconscious response of information searching in the change of pupil size in the process of observing the space. The results could be defined as following several points. First, it was possible to outline the unconscious response characteristics of pupil by analyzing sudden changes in pupil size as total, cumulative, and individual. The response characteristics using frequency and time can be utilized as the analytical method to examine the degree of interest of spatial components according to the purpose of analysis in the future. Second, according to the over ${\pm}5%$ of cumulative variation rate on the pupil size change, during in the 60 seconds, the continuous pupil dilation was used 25.2 seconds in 8.8 rounds and the pupil reduction was used 18.0 seconds in 7.0 rounds. Third, when the variation rate of ${\pm}5%$ or more was regarded as the sudden changes on pupil size by individual variation, the pupil dilation was 7.2 rounds of 8.6 seconds and pupil reduction was 6.0 seconds in 5.0 rounds. This means that the pupil increases 9.3% in one expansion and decreases -8.5% in the reduction process. As regarding pupil changes as cumulative rate, it appeared high change rate on pupil reduction but it became higher on pupil dilation in individual.

Association of Leptin Polymorphism with Production, Reproduction and Plasma Glucose Level in Iranian Holstein Cows

  • Moussavi, A. Heravi;Ahouei, M.;Nassiry, M.R.;Javadmanesh, A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제19권5호
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    • pp.627-631
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    • 2006
  • The objective of this study was to evaluate the association of genetic differences in the bovine leptin gene and milk yield, reproduction, body condition score (BCS), and plasma glucose level in Iranian Holstein cows. In total, two hundred and thirty eight cows were used and genotyped for a restricted fragment length polymorphism at the leptin gene locus. Two genotypes, AA and AB, have been distinguished which have the frequencies of 0.89 and 0.11, respectively. The genotypes were distributed according to the Hardy - Weinberg equilibrium ($x^2$ = 0.733). During the first 12 wk of lactation, milk yield and composition, live weight, BCS and plasma glucose were measured in 50 cows. Data were analyzed based on a repeated measures ANOVA. During this period, milk yield and composition, live weight, BCS and plasma glucose level were similar among the genotypes. The first cumulative 60-d milk yield, 305-d milk yield, days to first breeding, days open and days from first breeding to conception using previous lactation records were also analyzed using Standard Least Square within mixed models. Fixed effects were year, season, parity and age at calving, and sire. For the reproductive traits the cumulative first 60-d milk yield was also added to the model. Animal was fitted as a random effect. A significant association was detected between the RFLP-AB genotype and 305-d milk yield (p<0.05). The first 60-d cumulative milk yield was similar for the two genotypes (p = 0.21) and tended to be higher in the heterozygous cows. The heterozygous genotypes at the above mentioned locus had a trend to better reproductive performance than the homozygous. The results demonstrate that the RFLP B-allele can yield a higher 305-d milk production with a trend to better reproductive performance.

Measuring Fluid Balance in Patients with Cancers: Comparison between Cumulative Intake and Output Records and Body Weight Change (암환자의 수분 균형 상태 사정 방법 비교: 수분 섭취 및 배설량 측정법과 체중측정법)

  • Lee, Jin-Hong;Park, Hee-Jung;Kim, Jeong-Hwa;Suh, Eun-Young
    • Asian Oncology Nursing
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    • 제11권3호
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    • pp.247-253
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    • 2011
  • Purpose: The purpose of the study was to evaluate the accuracy of two different fluid intake measurement methods (fluid only vs. all dietary intake) in measuring fluid balance compared to body weight change among patients with cancers. Methods: A total of 60 cancer patients in an urban cancer center in South Korea participated in the study. Adult patients who were over 18 years old; having 24-hour I&O order; and taking either normal regular diet or soft blend diet were included. Demographic information and disease related information were also gathered. The data were analyzed using SPSS 18.0 program. Results: Measuring 'fluid only' for oral intake was a more accurate measure than measuring 'all dietary intake' (p=.026 vs. p=.094). Both methods had positive correlations with the amount of weight change (r=.329, p=.010; r=.303, p=.019). Measuring body weight was a more accurate and efficient way of evaluating the fluid balance than 24 hour cumulative I&O. Conclusion: Developing clinical manual for selecting proper patients who needs fluid balance monitoring is imperative. Administering weight check and/or 24 hour cumulative I&O should be considered thoroughly based on solid nursing evidence in future.

Prediction of HIV and AIDS Incidence Using a Back-calculation Model in Korea (후향연산 모형 (Back-calculation model)을 이용한 국내 HIV 감염자와 AIDS 환자의 추계)

  • Lee, Ju-Young;Goh, Un-Yeong;Kee, Mee-Kyung;Kim, Jee-Yun;Hwang, Jin-Soo
    • Journal of Preventive Medicine and Public Health
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    • 제35권1호
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    • pp.65-71
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    • 2002
  • Objective : To estimate the status of HIV infection and AIDS incidence using a back-calculation model in Korea. Methods : Back-calculation is a method for estimating the past infection rate using AIDS incidence data. The method has been useful for obtaining short-term projections of AIDS incidence and estimating previous HIV prevalence. If the density of the incubation periods is known, together with the AIDS incidence, we can estimate historical HIV infections and forecast AIDS incidence in any time period up to time t. In this paper, we estimated the number of HIV infections and AIDS incidence according to the distribution of various incubation periods Results : The cumulative numbers of HIV infection from 1991 to 1996 were $708{\sim}1,426$ in Weibull distribution and $918{\sim}1,980$ in Gamma distribution. The projected AIDS incidence in 1997 was $16{\sim}25$ in Weibull distribution and $13{\sim}26$ in Gamma distribution. Conclusions : The estimated cumulative HIV infections from 1991 to 1996 were $1.4{\sim}4.0$ times more than notified cumulative HIV infections. Additionally, the projected AIDS incidence in 1997 was less than the notified AIDS cases. The reason for this underestimation derives from the very low level of HIV prevalence in Korea, further research is required for the distribution of the incubation period of HIV infection in Korea, particularly for the effects of combination treatments.

Effect of Fiscal and Non-fiscal Variables on Regional Economy: The Case of 16 Wide-area Autonomous Communities in Korea (재정변수 및 비재정변수가 지역경제에 미치는 영향: 16개 시도를 중심으로)

  • Park, Wan Kyu;Kim, Du-Su
    • Journal of the Economic Geographical Society of Korea
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    • 제17권3호
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    • pp.554-566
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    • 2014
  • This paper analyses the relationship between regional economic power defined as GRDP per capita and various socioeconomic variables such as fiscal variables(revenue, expenditure, etc.) as well as nonfiscal variables(population, ratio of old population, unemployment rate, dependency ration) using the pooling data of 16 local governments from 1998 to 2012. To put it concretely, following the Granger causality test, regression analysis has been done with the regional economic power being the dependent and variables which have either one or two direction causality being independent variables. And test of cumulative effects has been done with variables showing statistical significance in the regression analysis. Local tax revenues per capita, expenditures of social development per capita and median age have positive effects, while dependency ratio has negative effect on regional economy. And national subsidy per capita, local tax revenues per capita, expenditures of social development per capita and median age all have cumulative effects on regional economy.

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Differences in Temperature between Korea and Japan, and its Inference in Rice Planting (한국(韓國)과 일본(日本)의 기온조건(氣溫條件)의 차이(差異)와 수도작(水稻作)에의 의미(意味))

  • Tani, Nobu Teru;Jung, Yeong-Sang
    • Korean Journal of Soil Science and Fertilizer
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    • 제18권4호
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    • pp.348-351
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    • 1985
  • Air temperature and its inference in rice planting were briefly analyzed to compare the difference in agricultural climatic condition in Korea and Japan. The results were as follows: 1. The mean air temperatures of August showed similar range at the same latitude in both countries but those of Korea in January were much lower than of Japan showing the greater annual range. 2. The daily fluctuations of air temperature during spring and autumn in Korea were greater than in Japan, and it was prominent in the daily minimum temperature. At the same cumulative temperature for maturing of rice plant, the cumulative cooling temperature lower than the certain marginal temperature, say $12^{\circ}C$ or $13^{\circ}C$, was greater in Korea than in Japan. Therefore, in analysis of temperature data relating to rice cropping, authors suggested that the cumulative cooling temperature be considered.

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