• Biomolecules & Therapeutics
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• v.7 no.4
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• pp.322-328
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• 1999

In this study, it was tested whether the changes of catecholamines and its metabolites are related with the changes of blood pressure(BP) induced by different levels of lead exposure. Adult male SD rats were exposed to lead by giving drinking water containing 50(low doses), 200 and 1,000 ppm(high doses) of lead(as lead acetate) or sodium acetate(for control groups, supplying an identical amount of acetate) for 7 or 16 weeks. The systolic BP was measured in the unanesthetized state by the tail-cuff technique. Levels of catecholamines and its metabolites in urine were measured by HPLC-ECD. Rats receiving 200 and 1,000 ppm developed an elevation of systolic BP at 3 and 7 weeks compared with week 0, but blood pressure levels at 16 weeks returned to normal. For the 50 ppm lead treated group, systolic BP increased significantly at 7 weeks and 16 weeks. The concentrations of norepinephrine and VMA in the urine of lead exposed rats changed similarly to the changes of blood pressure, but blood viscosity levels in all lead treated rats increased continuously during all lead treatment periods. This result suggests that the changes of catecholamines and its metabolites in urine by lead intoxication may influence the changes of blood pressure.

• Journal of Sensor Science and Technology
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• v.24 no.4
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• pp.239-246
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• 2015

Blood pressure is possible to diagnose a disease associated with blood pressure and judgment the current health of patients. Automatic blood pressure monitor capable of measuring a blood pressure easily in hospital and at home have become spread. In this study, we developed the blood pressure simulator (BPS) that can test the arm-type automatic blood pressure monitor that is commonly used in hospital. BPS is to produce a pressure similar to the pressure wave generated in the human blood using a servo disk motor. Then, using the silicon tube, it implements the situations such as human blood vessels, and to output the generated pressure waveform. Simply the BPS's phantom put on the cuff and it is able to simulate blood pressure. So anyone can quickly test the blood pressure monitor within one minute and it is possible to shorten the test time required for the automatic blood pressure monitor. In Performance test, the trends and the standard deviation of the values measured in the BPS is similar to the value of the measured pressure from people with normal blood pressure. Thus, the development BPS showed a possibility of taking into account the actual blood pressure measurement environment simulator.

• The Journal of the Korea Contents Association
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• v.15 no.11
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• pp.307-312
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• 2015

Mammography improves image quality that is on the increase day by day and get a picture with the pressure it is essential to reduce the dose. However, because due to the thickness of the cuff itself may increase the dose scattering lines is necessary study on the cuff material. Material that is currently being used in clinical Polycarbonate is a plastic and family. If you try to reduce the exposure of patients than itgie need to consider for the better material in this study to compare against a radiolucent line for amorphous plastic material of the plastic. results radiolucent and half layer, transmitting dose Pixel values HIPS, GPPS, ABS, Tritan, PC, PMMA showed high results in the net.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2003.04a
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• pp.51-51
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• 2003

The present study examined the effect of alcohol extract of Isaria sinclairii on blood pressure in spontaneously hypertensive rats (SHR). The blood pressure and heart rate were measured after treatment of alcohol extract of I. sinclairii by indirect tail cuff method and direct tn vivo model. Male SHR were treated with extracts for 2 or 4 weeks starting at 12 weeks of age. (omitted)

• Korean Journal of Bronchoesophagology
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• v.3 no.1
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• pp.185-187
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• 1997

Acquired tracheal dilatation is a state of abnormal tracheal dilatation developing from various causes. Tracheomalacia and tracheal dilatation can develop in respiratory distress patients with prolonged endotracheal intubation with assisted positive-pressure ventilation due to positive airway pressure and high cuff pressure. The authors have recently experienced one case of respiratory failure, cardiac arrest, and whole body emphysema after tracheostomy and portex tube insertion were performed to patient with the endotracheal intubation with assisted positive-pressure ventilation for two weeks in the septic shock resulted from colon perforation, who developed tracheal dilatation. We summarize diagnostic and therapeutic strategies of acquired tracheal dilatation for the prevention of emergency status and the management for that patients.

• Biomedical Engineering Letters
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• v.8 no.4
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• pp.399-404
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• 2018

The purpose of this study was to evaluate the accuracy of a mobile wireless digital automatic blood pressure monitor for clinical use and mobile health (mHealth). In this study, a manual sphygmomanometer and a digital blood pressure monitor were tested in 100 participants in a repetitive and sequential manner to measure blood pressure. The guidelines for measurement used the Korea Food & Drug Administration protocol, which reflects international standards, such as the American National Standard Institution/Association for the Advancement of Medical Instrumentation SP 10: 1992 and the British Hypertension Society protocol. Measurements were generally consistent across observers according to the measured mean ${\pm}SD$, which ranged in $0.1{\pm}2.6mmHg$ for systolic blood pressure (SBP) and $0.5{\pm}2.2mmHg$ for diastolic blood pressure (DBP). For the device and the observer, the difference in average blood pressure (mean${\pm}$SD) was $2.3{\pm}4.7mmHg$ for SBP and $2.0{\pm}4.2mmHg$ for DBP. The SBP and DBP measured in this study showed accurate measurements that satisfied all criteria, including an average difference that did not exceed 5 mmHg and a standard deviation that did not exceed 8 mmHg. The mobile wireless digital blood pressure monitor has the potential for clinical use and managing one's own health.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.7
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• pp.917-927
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• 2018

High blood pressure causes various cardiovascular diseases and is associated with mortality. Periodic self-monitoring and recording of blood pressure is very helpful in preventing the occurrence of secondary diseases caused by hypertension. However, existing cuff-type blood pressure monitors have many limitations. As an alternative of that, a method of estimating the blood pressure by measuring the velocity change of the blood flow using the photo plethysmography is widely known. However, photo plethysmography have a low correlation with blood flow. So, we will propose an algorithm for estimating blood pressure using the relationship between velocity change of blood flow measured by magnetic field instead of photo plethysmography and electrocardiogram. For this purpose, First, we analyzed the correlation between photo plethysmography and magneto plethysmography. the correlation between MPG and PPG was r = 0.9449. Second, we compared estimated blood pressure and measured blood pressure. In the four experiment each result was r = 0.5737, r = 0.7863, r = 0.5669, and r = 0.7445.

• Journal of Sensor Science and Technology
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• v.17 no.2
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• pp.87-94
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• 2008

Blood pressure (BP), one of the most important vital signs, is used to identify an emergency state and reflects the blood flow characteristics of the cardiovascular system. The conventional noninvasive method of measuring BP is inconvenient because patients must wear a cuff on their arm and the measurement process takes time. This paper proposes an algorithm for estimating the BP using the pulse transit time (PTT) of the photoplethysmography (PPG) and pressure pulse from finger at the same time as a more convenient way to measure the BP. After recording the electrocardiogram (ECG), measuring the pressure pulse, and performing PPG, we calculated the PTT from the acquired signals. Then, we used a multiple regression analysis to measure the systolic and diastolic BP indirectly. Comparing the BP measured indirectly using the proposed algorithm and the real BP measured with a sphygmomanometer, the systolic pressure had a mean error of ${\pm}3.240$ mmHg and a standard deviation of 2.530 mmHg, while the diastolic pressure had a satisfactory result, i.e., a mean error of ${\pm}1.807$ mmHg and a standard deviation of 1.396 mmHg. These results are more superior than existing method estimating blood pressure using the one PTT and satisfy the ANSI/AAMI regulations for certifying a sphygmomanometer i.e., the measurement error should be within a mean error of ${\pm}5$ mmHg and a standard deviation of 8 mmHg. These results suggest the possibility of applying our method to a portable, long-term BP monitoring system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.8
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• pp.1926-1938
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• 2009

In this study, detection system of the blood flow variation rate was implemented using the variation effect of bio electric impedance at time of the blood pressure measurement by means of impedance method. The blood pressure measurement was performed by the oscillometric method. The mean arterial pressure was calculated using maximum amplitude algorithm. The systolic and diastolic pressure were estimated by establishment of the various characteristic ratio according to mean arterial pressure range. Alternative static current source and lock_in amplifier were introduced to impedance measurement. The variation of blood volume was measured using variation bio impedance according to induced cuff pressure at measuring area.

• Journal of Biomedical Engineering Research
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• v.25 no.6
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• pp.605-609
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• 2004

Blood pressure (BP) is one of the important physiological parameters for diagnosing cardiovascula diseases by means of noninvasive method. Existing noninvasive methods for measuring arterial BP have to use cuff and difficult in measuring arterial BP continuously. Systolic blood pressure (SBP) and pulse transit time (PTT) have a kind of inverse relationship. We acquired PTT data when subjects were in relaxation and also after exercise. We performed the linear regression analysis for making the regression equations for each subject and the regression equation for all subjects. We compared the estimated SBP with the measured SBP to check the accuracy of our regression equations. From the result, the regression equations for each subject was appropriate according to the American National Standards Institute of the Association of the Advancement of Medical Instrument (ANSI/AAMI) which says that BP devices should have ±5mmHg mean of error and 8mmHg standard deviation of error. However, the regression equation for all subjects was not proper to ANSI/AAMI recommendation. The result means that, without cuff, we can continuously estimate each subject's SBP through PTT and indivisual calibration.