• Korean Journal of Environment and Ecology
• /
• v.25 no.4
• /
• pp.540-561
• /
• 2011

We carried out a study for ecological management and ideal vegetation structure selection on the shrine forest of 'Miwhang-sa' considering the species diversity and the vegetation structure analysis associated with global warming. We carried out the analyses of phytosociological vegetation structure, correlation between vegetation units and environmental variables, life form, species diversity, and species evenness. This study identified the vegetation units as 3 communities. The identified vegetation units are as follows: Quercus acuta community(DQ), Quercus serrata-Quercus variabilis community(QQ) and Celtis sinensis community(CS). According to the basis on the environmental variables; Ca, Mg and P, Celtis sinensis community and other communities were classified. Quecus serrata-Quercus variabilis comm. and Quercus acuta comm. were classified, according to the basis on the environmental variables; organic matter(OM), Ni and Zn. Sasa borealis as life form R1-2, dominated the herb layer and will dominate the herb and shrub layers. Species simplification is formed on herb layer and will be formed on shrub layer. The species diversity of Quercus serrata-Quercus variabilis community is higher than the one of Quercus acuta community, and the species diversity of shrine forest around Miwhang-sa was higher than the shrine forest around Nameun-sa where evergreen broad-leaved forests dominate. It is essential that the long-term vegetation management considering the vegetation units by phytosociological analysis, the species simplification problem of low layers by S. borealis and the species diversity and evenness in the shrine forest, Miwhang-sa.

• Polymer(Korea)
• /
• v.38 no.6
• /
• pp.702-707
• /
• 2014

Corneal endothelium is mono-inner cell layer of cornea and lay on Descmet's membrane which comprised of various proteins called extracellular matrix such as fibronectin, collagen, laminin, and proteoglycan, etc. In this study, we fabricated transparent poly(lactic-co-glycolic acid) (PLGA) film because PLGA is widely used for tissue engineering based on their properties. We investigated the behaviors of rabbit corneal endothelial cells (rCEnCs) on PLGA film surfaces coated with various cell-adhesive molecules like fibronectin, laminin, collagen type I and IV and FNC coating mix. The morphologic images, proliferation and adhesion assay, immunofluorescence for ZO-1 and $Na^+/K^+-ATPase$ and RT-PCR for expression of specific markers were conducted. These results showed that PLGA film plays a role as CEnC carriers in vitro and the cell-adhesive molecules give positive effects on the behaviors of rCEnC.

• Journal of Convergence for Information Technology
• /
• v.10 no.3
• /
• pp.7-15
• /
• 2020

As the paradigm shifts from treatment and provider-centered healthcare to prevention and consumer-centered healthcare, the integration of ICT convergence technology is calling for an era of digital healthcare industry revival in the Fourth Industrial Revolution. It is possible to provide individual customized medical services utilizing various medical data, and it is possible to provide various medical services that transcend time and space through integration with other industries. Such digital healthcare includes health, nutrition, exercise, and patient care, while the digital healthcare industry includes healthcare and IT related to medical devices, medical information systems, and healthcare platforms that can provide personal health and medical information. Due to the social demands of the aging and the increase of chronic diseases, digital healthcare is considered as an important policy in the fourth industrial revolution in Korea. In order for the digital healthcare industry to contribute to the prolongation of human life and the improvement of quality of life, it is urgent to develop related infrastructures, legal institutions, and prepare policies. In addition, it is important to activate convergent education to foster talents who will lead the digital healthcare industry. The purpose of this study was to examine the trends of the digital healthcare industry in the era of the fourth industrial revolution and the direction of government R & D policies, and to derive directions and suggestions for future development.

• Journal of Convergence for Information Technology
• /
• v.10 no.3
• /
• pp.48-57
• /
• 2020

This study focuses on the development of simple qualitative indicators for evaluating and selecting innovation leading companies that challenge National Award. Another purpose of this study is to complement the aspect in which the innovative or value of the companies' products, technologies, and services is only quantitatively evaluated. Existing evaluation indicators of national award have too many evaluation items and were not suitable for innovation-based company evaluation. The research approach is to select category for developing qualitative indicators based on previous studies and TF discussion. From the input-process-output-outcome point of view, we have set up an indicator system as a series of flows. Finally, five categories such as creativity, system excellence, customer value, performance, and ripple effects are selected as qualitative indicator. For these selected indicators, conceptual definitions and the main points of evaluation are described. And the system level evaluation and the ADLI approach are presented for reference. The appendix also includes examples of qualitative and quantitative evaluation of real companies using these indicators. However, this study implies the possibility that the evaluation results may vary depending on the level and perspective of the evaluator. We hoped that detailed research on candidate indicators that can be used as qualitative indicators and research on the development of mixed indicators(qualitative and quantitative) will continue in the future.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.32 no.2
• /
• pp.117-132
• /
• 2014

This paper had a purpose on analyzing result data from pan-sharpening, which have applied on the KOMPSAT-2 and -3 image. Particularly, the study focused on comparing each relative spectral response functions, which considers to cause color distortions of fused image. Two images from same time and location have been collected by KOMPSAT-2 and -3 to apply in the experiment. State-of-the-art algorithms of GIHS, GS1, GSA and GSA-CA were employed for analyzing the results in quantitatively and qualitatively. Following analysis of previous studies, GSA and GSA-CA methods resulted excellent quality in both of KOMPSAT-2/3 results, since they minimize spectral discordances between intensity and PAN image by the linear regression algorithm. It is notable that performances from KOMPSAT-2 and- 3 are not equal under same circumstances because of different spectral characteristics. In fact, KOMPSAT-2 is known as over-injection of low spatial resolution components of blue and green band, are greater than that of the PAN band. KOMPSAT-3, however, has been advanced in most of misperformances and weaknesses comparing from the KOMPSAT-2.

• Korean Journal of Clinical Pharmacy
• /
• v.20 no.1
• /
• pp.9-16
• /
• 2010

Purpose: 본 연구는 한국인 성인 조혈모세포이식환자를 대상으로 경구용 사이클로스포린의 집단약동학 분석을 통하여 사이클로스포린의 약동학적 파라미터에 영향을 미치는 요인 분석을 실시하고자 하였다. Methods: 2000년 12월부터 2006년 8월까지 서울대학교병원에서 동종조혈모세포이식을 받고 면역억제제로 사이클로스포린을 복용한 성인 백혈병환자를 대상으로 후향적으로 자료를 수집하였다. 사이클로스포린의 약동학에 영향을 미치는 인자로는 연령, 성별, 이식 후 날짜, 신기능, 공여자와의 관계, 질병의 종류, 혈중 빌리루빈 농도, 사이클로스포린의 대사를 유도하는 프레드니솔론의 투여량, 헤마토크리트, 사이클로스포린의 대사를 저해하는 약물의 병용여부 등을 검토하였다. 분석은 NONMEM$^{(R)}$ VI 프로그램을 이용하였으며, 변수를 추가하지 않은 기본 모형을 만든 후에 단계적인 요인의 추가와 제거를 통해 최종모형을 제작하였다. Results: 최종 상관 모형은 다음과 같다; CL/F (L/h) = $85.6{\times}e^{(0.646\;{\times}\;HCT/28.9\;+\;0.0464\;{\times}\;Gender)}$. 사이클로스포린의 겉보기 클리어런스는 환자의 성별이 남자일 때 또는 헤마토크릿이 감소할수록 증가하였다. 그 외 파라미터는 다음과 같이 계산되었다; $K_{\alpha}=0.0787\;(h^{-1})$; Q=57.1(L/kg/h); $V_{d-central\;compartment}$=1,100 (L); $V_{d-peripheral\;compartment}$ = 213,000(L). 개체간 편차는 40% 미만이었으며, 개체내 편차를 포함하는 잔차는 24.02%였다. Conclusions: 사이클로스포린의 약동학적 특징과 그 클리어런스에 영향을 끼칠 수 있는 임상적 요인을 이해하는 것은 환자 개개인의 용량과 용법의 결정 및 이상반응 발생의 예방에 유용할 수 있다. 한국인 조혈모세포이식환자에서 사이클로스포린의 약동학에 영향을 미치는 최종 파라미터를 구한 본 연구의 결과는 조혈모세포이식을 받은 한국인 성인환자에서 사이클로스포린의 모니터링 및 용량조절에 유용할 것으로 전망된다.

• Proceedings of the Korea Contents Association Conference
• /
• 2008.05a
• /
• pp.343-347
• /
• 2008

There are two kind of system in hotel for evaluating management. the first is infra system, for example Front management system - reservation system, C/I, C/O system, POS system , web system, call center management -, Back office system, interface system, and so on which manage direct control for hotel, and next is strategic system, for example BSC , CS . which is supporting hotel management. The purpose of this study was to find using the Balanced Scorecard to evaluate hotel management perfomance. Management performance is based on productivity, quality, time, effect, and responsiveness. Hotel economic value is not equal visual asset which is measured financial value. It is include hotel brand, image, customers who have good loyalty, employees who give customers special service, and systems which was affected by internal process. In conclusion, innovation, growth, internal system process, empioyee and customer have effect hotel performance. Therefore hotel has to know non-financial performance which has positively relate to financial performance.

• Weed & Turfgrass Science
• /
• v.1 no.4
• /
• pp.6-12
• /
• 2012

A fact-finding survey was conducted to obtain the basic information on nation-wide weed distribution and farmer's opinions to weed control strategy in paddy field. Most respondents considered Echinochloa spp., Monochloa vaginalis, Sagittaria trifolia, and Scirpus juncoides etc. as dominate weeds in paddy fields. And herbicide resistant weed species were M. vaginalis, S. juncoides, E. oryzicola and S. pygmaea etc. Purchase guidances for herbicide selection, experience of farmers was 34.0% and dealers recommendation was 33.9% at farmer's level. And paddy field herbicides application frequence were one time 15.6% but twice 75.6%. Preferred herbicides were ranked in the following order: oxadizone 12% EC, butachlor 5% GR, butachlor 33% CS, mefenacet pyrazodulfuron-ethyl 21.42% SC, and oxadiargyl 1.7% EC etc. in paddy fields. And in most preferred foliar herbicide were bentazone MCPA 38.6% SL and bentazone cyhalop-butyl 18.5% ME, 48.5% and 22.3%, respectively.

• Clinical and Experimental Reproductive Medicine
• /
• v.32 no.3
• /
• pp.231-242
• /
• 2005

연구목적: 본 연구는 아직 그 기능이 파악되지 않은 탈유비퀴틴효소 중 하나인 HIDE에 대한 기본적인 생화학적 특징과 고환에서의 발현 양상을 파악하고 있다. 연구재료 및 방법: 인간의 HIDE 유전자를 클로닝하여 효소활성이 있는지 세포 외 실험을 통해 확인하였고, 아미노산 서열을 분석하여 진화상 보존된 부분을 찾아 그 기능을 파악한 다음 HSP90과의 상호작용을 공동면역침전반응으로 확인하였다. HIDE의 조직별 발현양상을 파악하기 위해서 인간과 쥐의 RNA 블롯과 쥐의 단백질 블롯을 이용하여 각각 노던 블롯팅과 웨스턴 블롯팅을 수행하여 고환에서 많이 발현된다는 것을 알았고 이 사실을 바탕으로 쥐의 고환을 절개하여 면역조직화학반응으로써 고환 내의 HIDE 단백질의 발현양상을 파악하였다. 결　과: HIDE는 세포 외에서 유비퀴틴 잔기를 제거하는 탈유비퀴틴 활성이 있으나 세포 내에서 전체적인 유비퀴틴 복합체를 줄여주는 효과는 없었다. HIDE는 HSP90이라는 분자 샤페론과 상호작용한다. HIDE의 전사체는 고환에서 가장 많이 발현되며 다른 조직에서도 소량 발현된다. HIDE의 단백질은 웨스턴 블롯상에서 고환에서만 확인되었다. 고환 내에서의 HIDE의 발현양상은 왕성한 감수분열을 하는 정모세포에서 높았으며 지지세포나 정조세포에는 발현되지 않았다. 결　론: HIDE는 분자 샤페론 HSP90과 상호작용하며 고환 내의 감수분열 중인 세포에서 많이 발현되는 것으로 보아 감수분열이나 정자형성에 관여하는 것으로 보인다.

• Journal of Convergence for Information Technology
• /
• v.7 no.2
• /
• pp.91-99
• /
• 2017

The purpose of this study was to clarify the differences between the K-pop and B-boy dancers'characteristics based on the biomechanical variables through the isolation movement by independent variable t-test using spss 18.0. As a result, first, the CoM composite displacement of the K-pop dancer was larger than that of the B-boy(p<.05) in phase1 and phase2. Second, in phase2 and phase3, the movement speed of CoM was faster in K-pop dancer than in B-boy(p<.05). Third, in phase1, the planar angle between the body and pelvis was greater in the right planar angle of the K-pop dancer, while in the phase2 and phase3, the left planar angle of the B-boy was larger(p<.05). Fourth, the composite hip joint moments of B-boy were larger than those of K-pop in phase1, However, K-pop dancers showed greater moments in phase2, phase3 and phase4, and ankle joint moments in phase3(p<.05). Thus, even with the same isolation, we found that K-pop and B-boy dancers performed differently.