• Journal of Microbiology and Biotechnology
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• v.25 no.10
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• pp.1634-1639
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• 2015

Cytochrome P450 hydroxylase (CYP) in actinomycetes plays an important role in the biosynthesis and bioconversion of various secondary metabolites. Two unique CYPs named CYP-sb21 and CYP-pa1, which were identified from Sebekia benihana and Pseudonocardia autotrophica, respectively, were proven to transfer a hydroxyl group at the 4^th or 9^th N-methyl leucine position of immunosuppressive agent cyclosporin A (CsA). Interestingly, these two homologous CYPs showed different CsA regio-selectivities. CYP-sb21 exhibited preferential hydroxylation activity at the 4^th position over the 9^th position, whereas CYP-pa1 showed the opposite preference. To narrow down the CYP domain critical for CsA regio-selectivity, each CYP was divided into four domains, and each domain was swapped with its counterpart from the other CYP. A total of 18 hybrid CYPs were then individually tested for CsA regio-selectivity. Although most of the hybrid CYPs failed to exhibit a significant change in regio-selectivity in the context of CsA hydroxylation, hybrid CYP-pa1 swapped with the second domain of CYP-sb21 showed a higher preference for the 9^th position. Moreover, hybrid CYPsb21 containing seven amino acids from the 2nd domain of CYP-pa1 showed higher preference for the 4^th position. These results imply that the 2nd domain of CsA-specific CYP plays a critical role in CsA regio-selectivity, thereby setting the stage for biotechnological application of CsA regio-selective hydroxylation.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.7 no.1
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• pp.117-125
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• 1997

Ferroelastic $CsPbCl_3$ crystals were grown by the Czochralski method and Bridgman method. From XRD, DTA and the dielectric measurements, we investigated the structure and confirmed the phase transition temperatures of it. Using the polarizing microscope, we observed the ferroelastic domains and the temperature dependence of the domains. For the orientation states, we obtained the consistent result with the theoretical investigation by the crystallographical consideration. For Aizu species m3mF2/m(p) 12 orientation states are represented crystallographically.

• Korean Journal of Crystallography
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• v.11 no.1
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• pp.34-41
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• 2000

The group-theoretical approach analyzing the domain structure and the domain wall orientations of the ferroelastic crystal was introduced. These theoretical results were investigated by comparing them with the experimental results of several ferroelastic crystals, CsPbCl₃, Pb₃(PO₄)₂, and LiCsSO₄, which were grown by the Czochralski and solution methods, respectively. both results were agreed well and also consistent with those of previous works such s the strain method and the geometrical consideration. The group-theoretical approach showed that the ferroelastic domain walls must be the crystallographical prominent planes with fixed indices and classified by the symmetry elements characterizing the permissible domain walls. So the group-theoretical approach could be suggested as a new method for analyzing the structure of the ferroelastic domain and domain walls.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.2
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• pp.23-30
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• 2010

The research presents moisture content measuring and calibration method of road pavement, especially asphalt concrete pavement for performance evaluation or remaining life prediction using Time Domain Reflectometry(TDR) sensor, CS616 made by campbell INC. Before calibration test of CS616, accomplished a sensor verification tests. Verification test items were covering depth and interference effect of two CS616 sensors, temperature effects between $5^{\circ}C\sim25^{\circ}C$ and compaction ratio effects. Covering depth and interference effects between two CS616 sensors were just small and the effects of temperature and compaction ratio effected a Volumetric Moisture Contents at $\pm6%$ under disregard appeared with the fact that was possible. Also, obtained the calibration equation of the subgrade and subbase course, $R^2$ showed above of all 0.9.

• ETRI Journal
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• v.34 no.3
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• pp.429-438
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• 2012

This study presents two reversible data hiding schemes based on the coefficient shifting (CS) algorithm. The first scheme uses the CS algorithm with a mean predictor in the spatial domain to provide a large payload while minimizing distortion. To guard against manipulations, the second scheme uses a robust version of the CS algorithm with feature embedding implemented in the integer wavelet transform domain. Simulations demonstrate that both the payload and peak signal-to-noise ratio generated by the CS algorithm with a mean predictor are better than those generated by existing techniques. In addition, the marked images generated by the variant of the CS algorithm are robust to various manipulations created by JPEG2000 compression, JPEG compression, noise additions, (edge) sharpening, low-pass filtering, bit truncation, brightness, contrast, (color) quantization, winding, zigzag and poster edge distortion, and inversion.

• Journal of Advanced Navigation Technology
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• v.13 no.4
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• pp.600-609
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• 2009

We provide indifferentiable security analyses of pfMD, MDP, WPH, EMD, NI and CS hash domain extensions and their truncated versions. Unlike previous analytic techniques, the analytic technique considered in this paper is simple and easy. Moreover, the analytic technique can be generally applied to any types of hash domain extensions. That means that the technique can be used as an analyzing tool for any new developed hash function.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.13 no.4
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• pp.109-127
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• 2003

In this paper, we analyze the network architecture, authentication, and key agreement of GSM and UMTS to compare the handover between the systems. And then, we divide authentication and key agreement procedure of mobile subscribers into several cases and finally analyze the key agreement procedure when a handover occurs in a CS-Domain and a PS-Domain.

• Journal of the Korean Geosynthetics Society
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• v.12 no.2
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• pp.1-11
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• 2013

Water content of subgrade soil in water supply systems has a large effect on performance. Many researchers lately make use of time-domain reflectometry (TDR) probes to measure the soil water content of subgrade soil from monitoring. The laboratory calibration test of TDR probe should be performed with soil field, because TDR probe can cause an error by type, gradation, density, and temperature of soil. This study shows the laboratory calibration test using TDR CS616, TDR-P3, TDR-T3. The calibration equations of TDR were then proposed. It was confirmed from the study that the data of TDR probe monitored in field could be used to estimate the freezing, unfrozen water content, and matric suction of soil.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.9
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• pp.138-144
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• 2012

In this paper, we introduce the time-domain equalizer in orthogonal frequency division multiplexing (OFDM) systems using orthogonal matching pursuit (OMP) algorithm. Since OFDM system inserts guard intervals, it shows robust performance against multi-path fading. However, in Doppler channel, inter-carrier interference (ICI) occurs because an orthogonality of sub-carriers does not maintain. A least squares (LS) algorithm is common method of time-domain equalizer, but if a channel length is longer, the performance deteriorates by noise. The multi-path fading is a summation of the different delay signal. And that has sparse properties in time-domain. Because the OMP algorithm of the compressive sensing (CS) algorithm restores the channel by choosing the important elements of sparse channel, it can reduce the influence of noise. We simulate the performance of time-domain equalizer in OFDM system with various channel environments using OMP algorithm compared with other equalization method.

• 한국방재학회:학술대회논문집
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• 2010.02a
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• pp.89.1-89.1
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• 2010

본 연구는 토양의 함수비를 측정하기 위하여 TDR(Time Domain Reflectometry, 시간영역 광전자파 분석기) 방식의 함수센서(CS616)에 대한 올바른 보정시험을 제안하기 위하여 피복두께, 센서간 간섭 영향, 온도의 영향 및 다짐율 변화에 대한 실내 시험을 수행하였다. 시험 결과 피복두께, 센서간 간섭 영향 및 온도의 영향은 체적함수비의 크기에 미치는 영향은 크지 않은 것으로 나타났으며, 오히려 보정시험시 정확한 체적함수비 조건을 유지하는 것이 중요할 것으로 사료된다. 또한 보정시험을 수행할 때 다짐율까지 고려한 시험을 수행하는 노력에 비하여 얻어지는 체적함수비의 정확도의 크기는 다짐율과 주기를 고려하여 얻어진 회귀식을 살펴보면 주기에 비하여 상대적으로 영향이 작은 것으로 사료된다.